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[188913_at] 7TM receptor

Description C33A12.8 /REP_DB=WormBase Gene ID /WP=CE05354 /TR=Q18363 /GB=CAA92792.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=7TM receptor
Cluster 6grp_total > 10      4grp_total > 10      6grp_cgc > 54      6grp_total_sub > Hat      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 147
1 2 3 4 range
A 2.8
(-3)
A 		29.2
(-1.9)
A 		25.9
(-2.1)
A 		148.7
(3)
P 		146
B 24.9
(-3)
A 		26.5
(-2.7)
A 		37.2
(-0.6)
A 		55.1
(3)
A 		30
C 23.4
(-2)
A 		34.8
(-1.4)
A 		1.9
(-3)
A 		125
(3)
P 		123
avr 17
(-3) 		30.2
(-2.1) 		21.7
(-2.7) 		109.6
(3) 		93

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 77
1 2 3 4 5 6 range
A 9
(-1)
A 		1.5
(-3)
A 		24
(3)
A 		7
(-1.5)
A 		5.7
(-1.9)
A 		1.7
(-2.9)
A 		23
B 2.1
(-3)
A 		50.2
(3)
A 		30.6
(0.6)
A 		6.3
(-2.5)
A 		27.1
(0.1)
A 		3.7
(-2.8)
A 		48
C 3.2
(-2.9)
A 		78.7
(3)
M 		6.8
(-2.6)
A 		14.9
(-2)
A 		1.8
(-3)
A 		18
(-1.7)
A 		77
avr 4.8
(-3) 		43.5
(3) 		20.5
(-0.6) 		9.4
(-2.3) 		11.5
(-2) 		7.8
(-2.5) 		39
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 21
1 2 3 4 range
A 1
(-3)
A 		6.3
(-1.5)
A 		6.8
(-1.3)
A 		21.8
(3)
P 		21
B 7.9
(-1.5)
A 		6.6
(-3)
A 		8.6
(-0.6)
A 		11.7
(3)
A 		5
C 7.8
(-0.9)
A 		10
(-0.3)
A 		0.7
(-3)
A 		21.1
(3)
P 		20
avr 5.6
(-2.9) 		7.6
(-2) 		5.4
(-3) 		18.2
(3) 		13

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 24
1 2 3 4 5 6 range
A 1.7
(-1.4)
A 		0.5
(-2.9)
A 		5.2
(3)
A 		1.8
(-1.3)
A 		1.7
(-1.4)
A 		0.4
(-3)
A 		5
B 0.7
(-3)
A 		16.7
(3)
A 		7.4
(-0.5)
A 		1.7
(-2.6)
A 		11
(0.9)
A 		1.4
(-2.7)
A 		16
C 1.2
(-2.8)
A 		24
(3)
M 		1.7
(-2.7)
A 		3
(-2.4)
A 		0.6
(-3)
A 		6
(-1.6)
A 		23
avr 1.2
(-3) 		13.7
(3) 		4.8
(-1.3) 		2.2
(-2.5) 		4.4
(-1.5) 		2.6
(-2.3) 		13
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188913_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8688
Sequence Type Exemplar sequence
Representative Public ID C33A12.8 NCBI
Target Description C33A12.8 /REP_DB=WormBase Gene ID /WP=CE05354 /TR=Q18363 /GB=CAA92792.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=7TM receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069276(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069276 NCBI Caenorhabditis elegans Serpentine Receptor, class U family member (sru-6) (sru-6) mRNA, complete cds. 11/11 None
GENEFINDER00000009040 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:9490759:9492720:1 11/11 None
C33A12.8 ENSEMBL cdna:known chromosome:CEL140:IV:9490597:9491968:1 gene:C33A12.8 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:9490602-9491974(+) 100.0 100.0
Public Domain and Genome References
Gene Title 7TM receptor
Gene Symbol sru-6
Ensembl C33A12.8
Entrez Gene 183142 Entrez gene
SwissProt Q18363 EMBL-EBI
WormBase CE05354 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAA92792 Hypothetical protein C33A12.8 [Caenorhabditis elegans] ref|NP_501677.1| Serpentine Receptor, class U family member (sru-6) [Caenorhabditis elegans] 0.0
blast CAA92792 Hypothetical protein C33A12.8 [Caenorhabditis elegans] ref|NP_501677.1| Serpentine Receptor, class U family member (sru-6) [Caenorhabditis elegans] 1.0E-154
blast CAE74028 Hypothetical protein CBG21677 [Caenorhabditis briggsae] 1.0E-142
blast CAE74028 Hypothetical protein CBG21677 [Caenorhabditis briggsae] 1.0E-115
blast CAE74032 Hypothetical protein CBG21682 [Caenorhabditis briggsae] 1.0E-111
blast CAE74032 Hypothetical protein CBG21682 [Caenorhabditis briggsae] 3.0E-90
Protein Domains
Database ID Description E-Value
Pfam IPR003839 EMBL-EBI Protein of unknown function DUF215 4.2E-90
Pfam IPR003839 EMBL-EBI Protein of unknown function DUF215 4.2E-90
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_501677.1 7 31-53,65-87,115-137,158-180,208-230,251-273,288-310
C33A12.8 7 31-53,65-87,115-137,158-180,208-230,251-273,288-310
GENEFINDER00000009040 8 15-37,67-89,104-126,154-176,204-226,233-255,275-297,327-349
Sequence
Target Sequence 
>C. ELEGANS:188913_AT
ggttgtggtcggttttcctatgagcaattttaggttaaactcagttttattgaaaattgg
agttcctctaatttggatatatccgttgtttttcacatttttccttattccggctgtagg
tgtctgtcgtcaactgagttcaccttatccacttggagctgttcacatttactacgcaaa
tgctgcctttgggatgagaaactcctatttatacctctacaacactgttgcttggttaag
tctatccattttggccaacattctactctttttgaaagttttacaagcaaaatctcaaat
agtgagcttacaaaaacaaagtgtttcttataaagctgaattgtcaataacaataactac
tattgttatgattattttttatgttattaatggaggatttattttgatgtatcttctttt
ctatggcacaaactcttacttttcattacttgtcgttatcaaaccatttgctaatgattt
gcaaacttgtgtggttccgtggatt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGTTGTGGTCGGTTTTCCTATGAGC 366 507 429 Antisense
TATTCCGGCTGTAGGTGTCTGTCGT 388 665 534 Antisense
GTCTGTCGTCAACTGAGTTCACCTT 327 471 550 Antisense
AGTTCACCTTATCCACTTGGAGCTG 4 65 565 Antisense
GGAGCTGTTCACATTTACTACGCAA 418 521 583 Antisense
TACTACGCAAATGCTGCCTTTGGGA 655 645 598 Antisense
GAAACTCCTATTTATACCTCTACAA 548 357 626 Antisense
TTGGCCAACATTCTACTCTTTTTGA 587 695 679 Antisense
TGATGTATCTTCTTTTCTATGGCAC 113 567 833 Antisense
GGCACAAACTCTTACTTTTCATTAC 547 535 853 Antisense
GCAAACTTGTGTGGTTCCGTGGATT 517 315 909 Antisense
Sequence Source Affymetrix Proprietary Database