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[188887_s_at]

Description DC2.7 /REP_DB=WormBase Gene ID /WP=CE20636 /CHR=5 /FEA=Sanger Annotation /DEF=protein kinase (ST.LOUIS) TR:Q9UAW6 protein_id:AAD14728.1
Cluster 6grp_total > 47      4grp_total > 29      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 119
1 2 3 4 range
A 74.7
(2.2)
A 		59.4
(0.9)
A 		11.5
(-3)
A 		84.8
(3)
A 		73
B 117.9
(3)
A 		67.4
(0)
A 		29.4
(-2.2)
A 		15.3
(-3)
A 		103
C 38.6
(-1.6)
A 		84.3
(0.7)
A 		10.9
(-3)
A 		130.2
(3)
M 		119
avr 77.1
(3) 		70.4
(2.3) 		17.3
(-3) 		76.8
(3) 		60

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 85
1 2 3 4 5 6 range
A 112.8
(3)
A 		75.7
(-2.2)
A 		90.7
(-0.1)
A 		70.3
(-3)
A 		90.6
(-0.1)
A 		106.7
(2.1)
A 		43
B 87.1
(2.3)
M 		93.6
(3)
A 		41.5
(-3)
A 		53.7
(-1.6)
A 		62
(-0.6)
M 		93.6
(3)
P 		52
C 62
(-0.2)
A 		85.6
(1.7)
A 		62.9
(-0.1)
A 		78.5
(1.2)
A 		27.5
(-3)
A 		101
(3)
P 		74
avr 87.3
(1.1) 		85
(0.7) 		65
(-2.3) 		67.5
(-1.9) 		60
(-3) 		100.4
(3) 		40
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 35
1 2 3 4 range
A 27.2
(3)
A 		12.9
(-0.5)
A 		3
(-3)
A 		12.4
(-0.7)
A 		24
B 37.6
(3)
A 		16.6
(-0.7)
A 		6.8
(-2.4)
A 		3.3
(-3)
A 		34
C 12.8
(-0.4)
A 		24.2
(3)
A 		3.8
(-3)
A 		22
(2.4)
M 		20
avr 25.9
(3) 		17.9
(0.8) 		4.5
(-3) 		12.6
(-0.7) 		21

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 26
1 2 3 4 5 6 range
A 20.8
(-1.1)
A 		26.9
(2.7)
A 		19.8
(-1.7)
A 		17.8
(-3)
A 		27.3
(3)
A 		26
(2.2)
A 		10
B 30.3
(1.9)
M 		31.2
(2.1)
A 		10.1
(-3)
A 		14.2
(-2)
A 		25.2
(0.7)
M 		34.9
(3)
P 		25
C 23
(0.4)
A 		26.1
(1.1)
A 		16
(-1.3)
A 		15.8
(-1.3)
A 		8.9
(-3)
A 		33.8
(3)
P 		25
avr 24.7
(0.5) 		28.1
(1.7) 		15.3
(-3) 		15.9
(-2.8) 		20.5
(-1.1) 		31.6
(3) 		16
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 188887_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.15844
Sequence Type Exemplar sequence
Representative Public ID DC2.7 NCBI
Target Description DC2.7 /REP_DB=WormBase Gene ID /WP=CE20636 /CHR=5 /FEA=Sanger Annotation /DEF=protein kinase (ST.LOUIS) TR:Q9UAW6 protein_id:AAD14728.1
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001028589(11), NM_070758(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001028589 NCBI Caenorhabditis elegans DC2.7c (DC2.7) mRNA, complete cds. 11/11 None
NM_070758 NCBI Caenorhabditis elegans DC2.7a (DC2.7) mRNA, complete cds. 11/11 A 
DC2.7a ENSEMBL cdna:known chromosome:CEL140:V:228760:234497:-1 gene:DC2.7 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000026554 8/11 Cross Hyb Matching Probes None
Splice Variants
Entrez Total Refseq Isoforms Total Detected By This Probeset Refseq Probesets
178549 3 2 NM_001028589 188886_at (9), 188887_s_at (11)
NM_070758 188886_at (9), 188887_s_at (11)
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:227271-234497(-) 100.0 100.0
Public Domain and Genome References
Ensembl DC2.7
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast NP_001023760 DC2.7c [Caenorhabditis elegans] gb|AAX55694.1| Hypothetical protein DC2.7c [Caenorhabditis elegans] 0.0
blast NP_503159 DC2.7a [Caenorhabditis elegans] gb|AAD14728.2| Hypothetical protein DC2.7a [Caenorhabditis elegans] 0.0
blast NP_503160 DC2.7b [Caenorhabditis elegans] gb|AAK68289.1| Hypothetical protein DC2.7b [Caenorhabditis elegans] 1.0E-173
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-59
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 1.0E-62
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-37
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 5.0E-37
hanks 2.2.5 CaMK Group; CaMK II KIN1/SNF1/Nim1; SNF1 3.0E-62
hanks 1.4.7 AGC group; AGC IV GPCR kinases; DmGPRK1 4.0E-59
hanks 1.4.2 AGC group; AGC IV GPCR kinases; bARK2 4.0E-59
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 2.2E-59
Pfam IPR000719 EMBL-EBI Protein kinase 5.5E-70
Pfam IPR000719 EMBL-EBI Protein kinase 1.5E-70
Sequence
Target Sequence 
>C. ELEGANS:188887_S_AT
tcctacactcgctggttcaatgacgaatgcaccgaaagagatgcgtggtctgatcttggt
gctcgtgtaatcacacttctttgctcaattcttgctcacaacccaacacatcgagcgcca
attgagctcattgaacaggaccactggtttcagtttggtgatgaggaaactgttgaaatc
acttccgcttcatcaaccagttgcaactccgaagccaaatccagcaga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCCTACACTCGCTGGTTCAATGACG 375 591 1729 Antisense
GAGATGCGTGGTCTGATCTTGGTGC 64 395 1766 Antisense
GATCTTGGTGCTCGTGTAATCACAC 62 419 1780 Antisense
GTAATCACACTTCTTTGCTCAATTC 631 461 1795 Antisense
TCTTTGCTCAATTCTTGCTCACAAC 516 615 1806 Antisense
CCAACACATCGAGCGCCAATTGAGC 675 275 1831 Antisense
GAGCTCATTGAACAGGACCACTGGT 414 387 1852 Antisense
GGACCACTGGTTTCAGTTTGGTGAT 232 523 1866 Antisense
AAACTGTTGAAATCACTTCCGCTTC 334 127 1895 Antisense
TTCCGCTTCATCAACCAGTTGCAAC 427 697 1911 Antisense
CAACTCCGAAGCCAAATCCAGCAGA 227 187 1932 Antisense
Sequence Source Affymetrix Proprietary Database