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[188875_at] 7TM receptor

Description T04A11.8 /REP_DB=WormBase Gene ID /WP=CE13134 /TR=O18019 /GB=CAB05611.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=7TM receptor
Cluster 6grp_total > 10      4grp_total > 0      6grp_cgc > 55      6grp_total_sub > Hat      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 113
1 2 3 4 range
A 7.2
(-3)
A 		8
(-3)
A 		46.9
(-0.9)
A 		119.2
(3)
A 		112
B 46.6
(1)
A 		11
(-3)
A 		47.8
(1.2)
A 		63.8
(3)
A 		53
C 9.2
(-2.5)
A 		10.4
(-2.3)
A 		5.9
(-3)
A 		46.5
(3)
A 		41
avr 21
(-2) 		9.8
(-3) 		33.5
(-0.9) 		76.5
(3) 		67

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 48
1 2 3 4 5 6 range
A 7.9
(-2.2)
A 		2.4
(-3)
A 		41.7
(3)
A 		7.7
(-2.2)
A 		10
(-1.8)
A 		9.5
(-1.9)
A 		39
B 6.4
(-3)
A 		46.9
(3)
A 		28.9
(0.3)
A 		6.4
(-3)
A 		25.8
(-0.1)
A 		6.5
(-3)
A 		41
C 6.5
(-2.7)
A 		42
(2)
A 		7.1
(-2.7)
A 		5.2
(-2.9)
A 		4.5
(-3)
A 		49.9
(3)
A 		45
avr 6.9
(-2.9) 		30.4
(3) 		25.9
(1.9) 		6.4
(-3) 		13.4
(-1.3) 		22
(0.9) 		24
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 16
1 2 3 4 range
A 2.6
(-2.7)
A 		1.7
(-3)
A 		12.3
(1.1)
A 		17.4
(3)
A 		16
B 14.9
(3)
A 		2.7
(-3)
A 		11.1
(1.1)
A 		13.6
(2.4)
A 		12
C 3
(-2.1)
A 		3
(-2.1)
A 		2.1
(-3)
A 		7.8
(3)
A 		6
avr 6.8
(-0.5) 		2.5
(-3) 		8.5
(0.5) 		12.9
(3) 		10

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 16
1 2 3 4 5 6 range
A 1.5
(-2.6)
A 		0.9
(-3)
A 		9.1
(3)
A 		1.9
(-2.3)
A 		3
(-1.5)
A 		2.3
(-2)
A 		8
B 2.2
(-2.8)
A 		15.6
(3)
A 		7
(-0.7)
A 		1.7
(-3)
A 		10.5
(0.8)
A 		2.4
(-2.7)
A 		14
C 2.4
(-2.5)
A 		12.8
(1.5)
A 		1.8
(-2.7)
A 		1
(-3)
A 		1.5
(-2.8)
A 		16.7
(3)
A 		16
avr 2
(-2.6) 		9.8
(3) 		6
(0.3) 		1.5
(-3) 		5
(-0.5) 		7.1
(1) 		8
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188875_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9212
Sequence Type Exemplar sequence
Representative Public ID T04A11.8 NCBI
Target Description T04A11.8 /REP_DB=WormBase Gene ID /WP=CE13134 /TR=O18019 /GB=CAB05611.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=7TM receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069991(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069991 NCBI Caenorhabditis elegans Serpentine Receptor, class U family member (sru-19) (sru-19) mRNA, complete cds. 11/11 None
SNAP00000015163 ENSEMBL cdna:SNAP chromosome:CEL140:IV:12498509:12500384:1 9/11 None
GENEFINDER00000015174 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:12498509:12509982:1 9/11 None
T04A11.8 ENSEMBL cdna:known chromosome:CEL140:IV:12498509:12500384:1 gene:T04A11.8 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:12498514-12500390(+) 100.0 100.0
Public Domain and Genome References
Gene Title 7TM receptor
Gene Symbol sru-19
Ensembl T04A11.8
Entrez Gene 188046 Entrez gene
SwissProt O18019 EMBL-EBI
WormBase CE13134 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAB05613 Hypothetical protein T04A11.10 [Caenorhabditis elegans] ref|NP_502394.2| Serpentine Receptor, class U family member (sru-17) [Caenorhabditis elegans] 1.0E-179
blast CAA16355 Hypothetical protein Y45F10B.4 [Caenorhabditis elegans] ref|NP_502616.2| Serpentine Receptor, class U family member (sru-16) [Caenorhabditis elegans] 1.0E-173
blast CAB05611 Hypothetical protein T04A11.8 [Caenorhabditis elegans] ref|NP_502392.1| Serpentine Receptor, class U family member (sru-19) [Caenorhabditis elegans] 1.0E-171
blast CAB05611 Hypothetical protein T04A11.8 [Caenorhabditis elegans] ref|NP_502392.1| Serpentine Receptor, class U family member (sru-19) [Caenorhabditis elegans] 1.0E-132
blast CAE59871 Hypothetical protein CBG03349 [Caenorhabditis briggsae] 1.0E-106
blast CAB05611 Hypothetical protein T04A11.8 [Caenorhabditis elegans] ref|NP_502392.1| Serpentine Receptor, class U family member (sru-19) [Caenorhabditis elegans] 2.0E-89
blast CAA16355 Hypothetical protein Y45F10B.4 [Caenorhabditis elegans] ref|NP_502616.2| Serpentine Receptor, class U family member (sru-16) [Caenorhabditis elegans] 6.0E-82
Protein Domains
Database ID Description E-Value
Pfam IPR003839 EMBL-EBI Protein of unknown function DUF215 9.7E-55
Pfam IPR003839 EMBL-EBI Protein of unknown function DUF215 1.3E-48
Pfam IPR003839 EMBL-EBI Protein of unknown function DUF215 2.2E-49
Pfam IPR003839 EMBL-EBI Protein of unknown function DUF215 3.5E-65
Pfam IPR003839 EMBL-EBI Protein of unknown function DUF215 3.9E-93
Pfam IPR006096 EMBL-EBI Glu/Leu/Phe/Val dehydrogenase, C terminal 5.8E-8
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_502392.1 7 24-46,67-89,117-139,160-178,205-227,253-275,285-307
T04A11.8 7 24-46,67-89,117-139,160-178,205-227,253-275,285-307
SNAP00000015163 5 32-54,84-106,121-143,148-170,180-199
GENEFINDER00000015174 16 24-46,67-89,117-139,160-178,183-202,250-272,292-310,323-345,375-394,424-446,499-521,542-564,588-610,631-653,711-733,760-782
Sequence
Target Sequence 
>C. ELEGANS:188875_AT
gttatgctatatccagttctcttttcaactgttcgtttggtaatcacctacttcccaaat
cgacacgaggaaataaatagaaaaatattgaaacgtgtcatcccattgatccacgtttac
ccactacctatgttattcttcatgtttccagctcttggagtttgccggcaacatcattat
ccttatcgtttaggagctgtttatgttcattttattggatcatttaatggaattatgagt
gcaccaattacaattttaaactcggctatttggctaacagtctgtttgattttaaattgg
atactatatagaaaactaagaaaaattaagctgtcacagagcatatctcaattgagccaa
gtcggaaaaagcagaaaaattgaaatatcattgtcacttactacaactgcaatgtttttc
gcatacactaccaatttattctttttgggttcattcatcattgactacaatatcgccacg
tatcttgtggttttccgtccctttggttatgatttggagctgtgcgttgttccgct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTTATGCTATATCCAGTTCTCTTTT 443 447 385 Antisense
GTTCTCTTTTCAACTGTTCGTTTGG 425 443 400 Antisense
TGGTAATCACCTACTTCCCAAATCG 14 553 422 Antisense
GTTTACCCACTACCTATGTTATTCT 382 447 499 Antisense
ATTCTTCATGTTTCCAGCTCTTGGA 505 11 519 Antisense
TTTGCCGGCAACATCATTATCCTTA 434 667 545 Antisense
CTCGGCTATTTGGCTAACAGTCTGT 209 227 645 Antisense
GTTTTTCGCATACACTACCAATTTA 301 449 798 Antisense
GACTACAATATCGCCACGTATCTTG 682 371 847 Antisense
TTTCCGTCCCTTTGGTTATGATTTG 91 669 876 Antisense
ATTTGGAGCTGTGCGTTGTTCCGCT 556 17 896 Antisense
Sequence Source Affymetrix Proprietary Database