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[188854_s_at] Thioredoxin

Description Y49E10.4 /REP_DB=WormBase Gene ID /WP=CE22222 /TR=Q9XTU8 /GB=CAB11548.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Thioredoxin
Cluster 6grp_total > 95      4grp_total > 48      6grp_total_sub > Increase      6grp_rule_based > S5      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 90
1 2 3 4 range
A 60.7
(-3)
A 		93.3
(0.2)
A 		121.4
(3)
A 		116
(2.5)
A 		61
B 86.5
(-1.2)
A 		137.5
(2.2)
A 		149.8
(3)
A 		60.3
(-3)
A 		90
C 79
(-3)
A 		104.4
(-0.8)
A 		149.6
(3)
A 		100.6
(-1.2)
A 		71
avr 75.4
(-3) 		111.7
(0.4) 		140.3
(3) 		92.3
(-1.4) 		65

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 608
1 2 3 4 5 6 range
A 15
(-3)
A 		85.9
(-2.3)
A 		117.8
(-2)
A 		293.7
(-0.3)
M 		467.7
(1.5)
P 		623.2
(3)
P 		608
B 66.1
(-3)
A 		104
(-2.6)
A 		168.3
(-1.8)
A 		249.8
(-0.9)
P 		599.1
(3)
P 		437.8
(1.2)
P 		533
C 38.8
(-3)
A 		113.1
(-2.1)
A 		166.9
(-1.4)
A 		210.5
(-0.8)
A 		516.2
(3)
P 		440.4
(2)
P 		477
avr 40
(-3) 		101
(-2.2) 		151
(-1.6) 		251.3
(-0.4) 		527.7
(3) 		500.5
(2.7) 		488
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 39
1 2 3 4 range
A 22.1
(-0.9)
A 		20.3
(-1.7)
A 		31.7
(3)
A 		17
(-3)
A 		15
B 27.6
(1)
A 		34
(2.8)
A 		34.7
(3)
A 		12.9
(-3)
A 		22
C 26.1
(-1.4)
A 		30
(-0.8)
A 		52.1
(3)
A 		17
(-3)
A 		35
avr 25.3
(-0.6) 		28.1
(0.1) 		39.5
(3) 		15.6
(-3) 		24

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 241
1 2 3 4 5 6 range
A 2.8
(-3)
A 		30.5
(-1.9)
A 		25.7
(-2.1)
A 		74.5
(-0.1)
M 		141.1
(2.6)
P 		151.7
(3)
P 		149
B 23
(-3)
A 		34.6
(-2.7)
A 		40.9
(-2.5)
A 		66.2
(-1.8)
P 		243.4
(3)
P 		163.2
(0.8)
P 		220
C 14.4
(-3)
A 		34.5
(-2.2)
A 		42.5
(-1.9)
A 		42.3
(-1.9)
A 		167
(3)
P 		147.4
(2.2)
P 		153
avr 13.4
(-3) 		33.2
(-2.3) 		36.4
(-2.2) 		61
(-1.3) 		183.8
(3) 		154.1
(2) 		170
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 188854_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6712
Sequence Type Exemplar sequence
Representative Public ID Y49E10.4 NCBI
Target Description Y49E10.4 /REP_DB=WormBase Gene ID /WP=CE22222 /TR=Q9XTU8 /GB=CAB11548.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Thioredoxin
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_067212(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_067212 NCBI Caenorhabditis elegans Y49E10.4 (Thioredoxin) mRNA, complete cds. 11/11 None
SNAP00000016073 ENSEMBL cdna:SNAP chromosome:CEL140:III:12378917:12380437:-1 11/11 None
GENEFINDER00000016115 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:12378917:12380437:-1 11/11 None
Y49E10.4 ENSEMBL cdna:known chromosome:CEL140:III:12378917:12380464:-1 gene:Y49E10.4 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:12378912-12380433(-) 100.0 100.0
Public Domain and Genome References
Gene Title Thioredoxin
Ensembl Y49E10.4
Entrez Gene 176664 Entrez gene
SwissProt Q9XTU8 EMBL-EBI
WormBase CE22222 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6118 electron transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5489 electron transporter activity inferred from electronic annotation QuickGO AmiGO
16853 isomerase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB11548 Hypothetical protein Y49E10.4 [Caenorhabditis elegans] ref|NP_499613.1| Y49E10.4 [Caenorhabditis elegans] 0.0
blast CAE66488 Hypothetical protein CBG11768 [Caenorhabditis briggsae] 1.0E-171
blast CAE65837 Hypothetical protein CBG10962 [Caenorhabditis briggsae] 1.0E-131
Protein Domains
Database ID Description E-Value
Pfam IPR006662 EMBL-EBI Thioredoxin type domain 5.6E-38
Pfam IPR006662 EMBL-EBI Thioredoxin type domain 8.0E-43
Sequence
Target Sequence 
>C. ELEGANS:188854_S_AT
gacgatcaaattcttcgctccaggtacatcatcagcttccgatgcagaggattatcaagg
tggacgtacttcaaccgatctgatttcctacgcagaatccaagtatgatgactttggagc
agctccagaagttgttgagggaaccggcaaagctgtagttgaaaccgtgtgcaaggacaa
gcaattgtgcattttcacattccttccgagcattttcgactgccaatccaagtgccgaaa
acaaaaaatcgatatgctgaatgaattagcgacgatcttcaaaaaacgatcattcggatg
ggtttggatggaaggcggagcacaggaaaacgtccagagagcatttgaaattggagatta
cggattcccggtgctcatcgcgatgagcccgaagaaaatgatgtatagcacacaaattgg
acaattttctgttgatgggatcaaggaattcttgaatgcggtcaattatggaaaaggaag
agttctagaaattaagcccacgcatctttcc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GACGATCAAATTCTTCGCTCCAGGT 66 379 696 Antisense
CTCCAGGTACATCATCAGCTTCCGA 654 235 713 Antisense
AAGGTGGACGTACTTCAACCGATCT 476 159 752 Antisense
TCAACCGATCTGATTTCCTACGCAG 500 631 766 Antisense
AGTATGATGACTTTGGAGCAGCTCC 287 63 797 Antisense
GAGGGAACCGGCAAAGCTGTAGTTG 637 401 832 Antisense
CACATTCCTTCCGAGCATTTTCGAC 122 197 891 Antisense
TCGACTGCCAATCCAAGTGCCGAAA 101 601 911 Antisense
GGAGATTACGGATTCCCGGTGCTCA 539 517 1048 Antisense
CCGGTGCTCATCGCGATGAGCCCGA 535 265 1063 Antisense
AGAAATTAAGCCCACGCATCTTTCC 249 71 1182 Antisense
Sequence Source Affymetrix Proprietary Database