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[188841_at] xanthine dehydrogenase

Description B0222.9 /REP_DB=WormBase Gene ID /WP=CE06700 /GB=AAK71353.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=xanthine dehydrogenase
Cluster 4grp_highest_8_8 > 53      4grp_high_8_8 > 17      6grp_total > 24      4grp_total > 31      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 101
1 2 3 4 range
A 156.8
(3)
P 		109.9
(-1.9)
P 		99.8
(-3)
P 		121
(-0.8)
P 		57
B 167.4
(3)
P 		74.2
(-3)
P 		123.6
(0.2)
P 		161.8
(2.6)
P 		93
C 175.3
(3)
P 		139
(0.2)
P 		97.4
(-3)
P 		143.6
(0.6)
P 		78
avr 166.5
(3) 		107.7
(-2.9) 		106.9
(-3) 		142.1
(0.5) 		60

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 57
1 2 3 4 5 6 range
A 77.6
(3)
A 		68
(1.8)
P 		76.2
(2.8)
P 		47.5
(-0.8)
M 		29.7
(-3)
M 		43.3
(-1.3)
A 		48
B 72.9
(1.5)
M 		83.8
(3)
P 		67.4
(0.8)
P 		39.6
(-3)
A 		56
(-0.8)
A 		50.7
(-1.5)
P 		44
C 86.3
(3)
P 		54.5
(-1.7)
P 		64.6
(-0.2)
P 		67.8
(0.3)
A 		59.6
(-0.9)
P 		45.5
(-3)
P 		41
avr 78.9
(3) 		68.8
(1.1) 		69.4
(1.2) 		51.6
(-2.1) 		48.4
(-2.6) 		46.5
(-3) 		32
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 40
1 2 3 4 range
A 57.1
(3)
P 		23.9
(-2.1)
P 		26.1
(-1.7)
P 		17.7
(-3)
P 		39
B 53.4
(3)
P 		18.3
(-3)
P 		28.6
(-1.2)
P 		34.5
(-0.2)
P 		35
C 58
(3)
P 		40
(-0.2)
P 		33.9
(-1.3)
P 		24.2
(-3)
P 		34
avr 56.2
(3) 		27.4
(-2.6) 		29.5
(-2.2) 		25.5
(-3) 		31

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 23
1 2 3 4 5 6 range
A 14.3
(-0.9)
A 		24.2
(3)
P 		16.6
(0)
P 		12
(-1.8)
M 		9
(-3)
M 		10.5
(-2.4)
A 		15
B 25.4
(2.1)
M 		27.9
(3)
P 		16.4
(-1)
P 		10.5
(-3)
A 		22.8
(1.2)
A 		18.9
(-0.1)
P 		17
C 32
(3)
P 		16.6
(-2)
P 		16.5
(-2.1)
P 		13.6
(-3)
A 		19.3
(-1.1)
P 		15.2
(-2.5)
P 		18
avr 23.9
(3) 		22.9
(2.5) 		16.5
(-0.7) 		12
(-3) 		17
(-0.5) 		14.9
(-1.5) 		12
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188841_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11457
Sequence Type Exemplar sequence
Representative Public ID B0222.9 NCBI
Target Description B0222.9 /REP_DB=WormBase Gene ID /WP=CE06700 /GB=AAK71353.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=xanthine dehydrogenase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Genome Target Overlap based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade B annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_072976
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
GENEFINDER00000040468 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:9171029:9175586:-1 None
SNAP00000040461 ENSEMBL cdna:SNAP chromosome:CEL140:V:9171029:9175586:-1 None
B0222.9 ENSEMBL cdna:known chromosome:CEL140:V:9170987:9175586:-1 gene:B0222.9 A 
NM_072976 NCBI Caenorhabditis elegans B0222.9 (B0222.9) mRNA, complete cds. A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:9168516-9175587(-) 100.0 100.0
Public Domain and Genome References
Gene Title xanthine dehydrogenase
Ensembl B0222.9
Entrez Gene 179299 Entrez gene
SwissProt Q960A1 EMBL-EBI
WormBase CE32787 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6118 electron transport inferred from electronic annotation QuickGO AmiGO
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
5489 electron transporter activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
16491 oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAK71353 Hypothetical protein B0222.9 [Caenorhabditis elegans] ref|NP_505377.2| B0222.9 [Caenorhabditis elegans] 0.0
blast NP_500531 F15E6.6 [Caenorhabditis elegans] gb|AAB92058.2| Hypothetical protein F15E6.6 [Caenorhabditis elegans] 0.0
blast CAE72122 Hypothetical protein CBG19218 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR008274 EMBL-EBI Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding 1.0E-126
Pfam IPR002346 EMBL-EBI Molybdopterin dehydrogenase, FAD-binding 9.8E-4
Pfam IPR000674 EMBL-EBI Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead 8.9E-31
Pfam IPR002888 EMBL-EBI [2Fe-2S]-binding 1.7E-57
Pfam IPR001041 EMBL-EBI Ferredoxin 1.5E-11
Pfam IPR008274 EMBL-EBI Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding 1.0E-126
Pfam IPR000674 EMBL-EBI Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead 5.2E-55
Sequence
Target Sequence 
>C. ELEGANS:188841_AT
gacacaacaatctactgcaacactaaacaactgcaaaactaaacaatgccgtgattgcta
taaagatctcagaagccagttgcgaaaagtcggtcttcttccaggaaccattgaccaggt
gtttcacaatcagcggaacttcacaacttgtcaaaaatatagatttgcaagacaggataa
aggagtctatgagaagaaaaagaaagccaaacaacattatgattgggattatgtagaata
tgatgaagatgaagatgatgattacttttgggatggattattttggaagaagaagagaaa
tgtattaaagaaaattgtaaaacgagacgttgaagctactactgcaatttcacaaccacc
taacagtacagcaatgaactcaaccggaattataggatacgcgtcatgccaaactggaac
ccaacagttgaatgtgctacgaaatgacagcgggaaattgattccaatatcggtatcagc
tggaatcaattgtgaatgtagattagcagttggatcaacacttgaatcactcgtacttgg
acaaggaatttccaaagcaatgccgccaattgacacaactagtac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GACACAACAATCTACTGCAACACTA 103 367 3675 Antisense
GTTGCGAAAAGTCGGTCTTCTTCCA 586 437 3753 Antisense
CTTCTTCCAGGAACCATTGACCAGG 78 221 3769 Antisense
GACCAGGTGTTTCACAATCAGCGGA 365 383 3787 Antisense
ATCAGCGGAACTTCACAACTTGTCA 260 29 3803 Antisense
AACGAGACGTTGAAGCTACTACTGC 198 145 3995 Antisense
ACTACTGCAATTTCACAACCACCTA 480 101 4012 Antisense
ACAACCACCTAACAGTACAGCAATG 84 107 4026 Antisense
GGATACGCGTCATGCCAAACTGGAA 318 509 4069 Antisense
ACACTTGAATCACTCGTACTTGGAC 698 107 4192 Antisense
TGCCGCCAATTGACACAACTAGTAC 526 583 4235 Antisense
Sequence Source Affymetrix Proprietary Database