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[188838_at] 7TM receptor

Description T21B4.9 /REP_DB=WormBase Gene ID /WP=CE16434 /TR=O18104 /GB=CAB03376.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=7TM receptor
Cluster 6grp_total > 83      4grp_total > 05      6grp_cgc > 86      6grp_cgc_sub > 04      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 118
1 2 3 4 range
A 60
(1.4)
A 		8.6
(-3)
A 		51.7
(0.7)
A 		79.3
(3)
A 		71
B 77.2
(3)
A 		69.9
(2.1)
A 		30.2
(-3)
A 		68.2
(1.9)
A 		47
C 38.2
(-2.4)
A 		31.4
(-2.8)
A 		27.8
(-3)
A 		126.7
(3)
P 		99
avr 58.5
(-0.6) 		36.6
(-3) 		36.6
(-3) 		91.4
(3) 		55

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 63
1 2 3 4 5 6 range
A 41.8
(-1.2)
A 		29.3
(-3)
A 		63.4
(1.9)
A 		63.3
(1.9)
A 		71
(3)
A 		69.6
(2.8)
A 		42
B 73.6
(3)
A 		61.1
(1.6)
A 		58.6
(1.3)
A 		69.6
(2.5)
A 		57.8
(1.2)
A 		21.5
(-3)
A 		52
C 10.7
(-3)
A 		46.6
(0.5)
A 		43.3
(0.2)
A 		67.1
(2.6)
A 		71.6
(3)
A 		45.6
(0.4)
A 		61
avr 42
(-3) 		45.7
(-2.1) 		55.1
(0.2) 		66.7
(3) 		66.8
(3) 		45.6
(-2.1) 		25
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 23
1 2 3 4 range
A 21.8
(3)
A 		1.9
(-3)
A 		13.5
(0.5)
A 		11.6
(-0.1)
A 		20
B 24.6
(3)
A 		17.3
(0.5)
A 		7
(-3)
A 		14.5
(-0.4)
A 		18
C 12.6
(-1.3)
A 		9
(-3)
A 		9.7
(-2.7)
A 		21.4
(3)
P 		12
avr 19.7
(3) 		9.4
(-3) 		10.1
(-2.6) 		15.8
(0.7) 		10

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 22
1 2 3 4 5 6 range
A 7.7
(-3)
A 		10.4
(-1.8)
A 		13.8
(-0.3)
A 		16
(0.6)
A 		21.4
(3)
A 		17
(1.1)
A 		14
B 25.6
(3)
A 		20.3
(1.2)
A 		14.2
(-0.9)
A 		18.4
(0.5)
A 		23.5
(2.3)
A 		8
(-3)
A 		18
C 4
(-3)
A 		14.2
(0.2)
A 		11
(-0.8)
A 		13.5
(-0)
A 		23.2
(3)
A 		15.3
(0.5)
A 		19
avr 12.4
(-3) 		15
(-1.5) 		13
(-2.7) 		16
(-0.9) 		22.7
(3) 		13.4
(-2.4) 		10
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188838_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3586
Sequence Type Exemplar sequence
Representative Public ID T21B4.9 NCBI
Target Description T21B4.9 /REP_DB=WormBase Gene ID /WP=CE16434 /TR=O18104 /GB=CAB03376.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=7TM receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064272(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_064272 NCBI Caenorhabditis elegans Serpentine Receptor, class H family member (srh-70) (srh-70) mRNA, complete cds. 11/11 None
GENEFINDER00000006704 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:12514888:12517350:-1 11/11 None
T21B4.9 ENSEMBL cdna:known chromosome:CEL140:II:12516656:12517761:-1 gene:T21B4.9 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:12516652-12517758(-) 100.0 100.0
Public Domain and Genome References
Gene Title 7TM receptor
Gene Symbol srh-70
Ensembl T21B4.9
Entrez Gene 188678 Entrez gene
SwissProt O18104 EMBL-EBI
WormBase CE16434 Wormbase
Functional Annotations
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4930 G-protein coupled receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB03376 Hypothetical protein T21B4.9 [Caenorhabditis elegans] ref|NP_496673.1| Serpentine Receptor, class H family member (srh-70) [Caenorhabditis elegans] 0.0
blast CAB03375 Hypothetical protein T21B4.8 [Caenorhabditis elegans] ref|NP_496672.1| Serpentine Receptor, class H family member (srh-61) [Caenorhabditis elegans] 1.0E-107
blast CAB03374 Hypothetical protein T21B4.7 [Caenorhabditis elegans] ref|NP_496671.1| Serpentine Receptor, class H family member (srh-69) [Caenorhabditis elegans] 2.0E-92
blast CAB03376 Hypothetical protein T21B4.9 [Caenorhabditis elegans] ref|NP_496673.1| Serpentine Receptor, class H family member (srh-70) [Caenorhabditis elegans] 2.0E-86
blast CAD56599 Hypothetical protein T21B4.14 [Caenorhabditis elegans] ref|NP_496670.2| Serpentine Receptor, class H family member (srh-73) [Caenorhabditis elegans] 2.0E-80
blast AAG45575 Serpentine receptor, class h protein 62 [Caenorhabditis elegans] ref|NP_503190.1| Serpentine Receptor, class H family member (srh-62) [Caenorhabditis elegans] 1.0E-38
Protein Domains
Database ID Description E-Value
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 1.2E-72
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 1.9E-62
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_496673.1 7 35-52,65-87,107-129,150-172,216-238,255-277,292-311
T21B4.9 7 35-52,65-87,107-129,150-172,216-238,255-277,292-311
GENEFINDER00000006704 6 29-51,95-117,134-156,258-280,300-322,337-359
Sequence
Target Sequence 
>C. ELEGANS:188838_AT
tagtgggcatagcctgcttagcccctatgacatttattattcccgagcaaaacaaagcga
agttagatatcttaaagacattcccctgtcccaccaaagaattcttcgcaacctcgacca
ccgtattcaccatcgacccatattgggagaccttcatcgcaaactccttcaaaatcaccc
gcctggtgtctggacttcaagttatatttttctcatcgtgttgcatatactacctatgca
tttcaaaaaccacaatatcacttcaaactcggcagtatcaaattcgttccttca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TAGTGGGCATAGCCTGCTTAGCCCC 518 653 485 Antisense
GCCCCTATGACATTTATTATTCCCG 345 285 505 Antisense
TATCTTAAAGACATTCCCCTGTCCC 428 567 552 Antisense
CAAAGAATTCTTCGCAACCTCGACC 333 191 579 Antisense
CGTATTCACCATCGACCCATATTGG 400 247 606 Antisense
CCCATATTGGGAGACCTTCATCGCA 213 259 621 Antisense
CTTCATCGCAAACTCCTTCAAAATC 388 221 636 Antisense
TCAAAATCACCCGCCTGGTGTCTGG 567 627 653 Antisense
CTCATCGTGTTGCATATACTACCTA 247 229 696 Antisense
ATATCACTTCAAACTCGGCAGTATC 697 19 739 Antisense
CGGCAGTATCAAATTCGTTCCTTCA 250 243 754 Antisense
Sequence Source Affymetrix Proprietary Database