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[188809_at] 7TM receptor

Description T21B4.6 /REP_DB=WormBase Gene ID /WP=CE16431 /TR=O18100 /GB=CAB03372.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=7TM receptor
Cluster 6grp_total > 40      4grp_total > 18      6grp_cgc > 82      6grp_cgc_sub > 03      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 75
1 2 3 4 range
A 9.8
(-3)
A 		41.5
(-0.5)
A 		19.5
(-2.2)
A 		84.5
(3)
P 		75
B 17.3
(-3)
A 		33.1
(3)
A 		23.8
(-0.5)
A 		25.8
(0.2)
P 		16
C 30.9
(0.6)
A 		31.2
(0.7)
A 		12.3
(-3)
A 		43.2
(3)
A 		31
avr 19.3
(-2.9) 		35.3
(0.1) 		18.5
(-3) 		51.2
(3) 		33

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 32
1 2 3 4 5 6 range
A 15.1
(-0.4)
A 		18.8
(0.6)
A 		10.4
(-1.6)
A 		28.1
(3)
A 		5.2
(-3)
A 		18.9
(0.6)
A 		23
B 22.4
(0.7)
A 		25.7
(1.4)
A 		33.1
(3)
A 		19.9
(0.2)
A 		5.2
(-3)
A 		6.5
(-2.7)
A 		28
C 22.5
(-0)
A 		23.2
(0.1)
A 		37.6
(3)
A 		7.6
(-3)
A 		20.2
(-0.5)
A 		25.3
(0.5)
A 		30
avr 20
(0.5) 		22.6
(1.4) 		27
(3) 		18.5
(-0) 		10.2
(-3) 		16.9
(-0.6) 		17
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 9
1 2 3 4 range
A 3.6
(-3)
A 		9
(0.7)
A 		5.1
(-2)
A 		12.4
(3)
P 		9
B 5.5
(-3)
A 		8.2
(3)
A 		5.5
(-3)
A 		5.5
(-3)
P 		3
C 10.2
(3)
A 		9
(1.8)
A 		4.3
(-3)
A 		7.3
(0.1)
A 		6
avr 6.4
(-0.7) 		8.7
(3) 		5
(-3) 		8.4
(2.5) 		4

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 8
1 2 3 4 5 6 range
A 2.8
(-1.7)
A 		6.7
(2.6)
A 		2.3
(-2.2)
A 		7.1
(3)
A 		1.6
(-3)
A 		4.6
(0.3)
A 		6
B 7.8
(2.3)
A 		8.5
(3)
A 		8
(2.5)
A 		5.3
(-0)
A 		2.1
(-3)
A 		2.4
(-2.7)
A 		6
C 8.3
(2)
A 		7.1
(1.1)
A 		9.6
(3)
A 		1.5
(-3)
A 		6.5
(0.7)
A 		8.5
(2.2)
A 		8
avr 6.3
(1.4) 		7.4
(3) 		6.6
(1.8) 		4.6
(-1.2) 		3.4
(-3) 		5.2
(-0.3) 		4
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188809_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2743
Sequence Type Exemplar sequence
Representative Public ID T21B4.6 NCBI
Target Description T21B4.6 /REP_DB=WormBase Gene ID /WP=CE16431 /TR=O18100 /GB=CAB03372.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=7TM receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064268(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_064268 NCBI Caenorhabditis elegans Serpentine Receptor, class H family member (srh-67) (srh-67) mRNA, complete cds. 11/11 None
GENEFINDER00000006702 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:12508853:12510038:1 11/11 None
T21B4.6 ENSEMBL cdna:known chromosome:CEL140:II:12508853:12510038:1 gene:T21B4.6 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000006688 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:12508849-12510035(+) 100.0 100.0
Public Domain and Genome References
Gene Title 7TM receptor
Gene Symbol srh-67
Ensembl T21B4.6
Entrez Gene 188675 Entrez gene
SwissProt O18100 EMBL-EBI
WormBase CE16431 Wormbase
Functional Annotations
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4930 G-protein coupled receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB03372 Hypothetical protein T21B4.6 [Caenorhabditis elegans] ref|NP_496669.1| Serpentine Receptor, class H family member (srh-67) [Caenorhabditis elegans] 0.0
blast CAB03372 Hypothetical protein T21B4.6 [Caenorhabditis elegans] ref|NP_496669.1| Serpentine Receptor, class H family member (srh-67) [Caenorhabditis elegans] 1.0E-172
blast CAB03373 Hypothetical protein T21B4.5 [Caenorhabditis elegans] ref|NP_496668.1| Serpentine Receptor, class H family member (srh-68) [Caenorhabditis elegans] 1.0E-148
blast CAB03373 Hypothetical protein T21B4.5 [Caenorhabditis elegans] ref|NP_496668.1| Serpentine Receptor, class H family member (srh-68) [Caenorhabditis elegans] 1.0E-135
blast T25056 hypothetical protein T21B4.10 - Caenorhabditis elegans 1.0E-110
blast T25056 hypothetical protein T21B4.10 - Caenorhabditis elegans 1.0E-108
Protein Domains
Database ID Description E-Value
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 3.9E-123
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_496669.1 7 29-51,70-92,107-129,150-172,216-238,255-277,287-309
T21B4.6 7 29-51,70-92,107-129,150-172,216-238,255-277,287-309
GENEFINDER00000006702 6 54-76,91-113,134-156,200-222,239-261,271-293
Sequence
Target Sequence 
>C. ELEGANS:188809_AT
acgtattggtttctcgccaacttcttcgcatttatgattttttcggtcataaatttcctg
aatatcccggatccagatcaggcaagaatagatatcttggagatccttccatgccccacc
aaagagttcttcacagagcccttctttgtgctcgccgctccaggattctgggaagactat
atggttacgatctcttcattgctaaacctggcgattatatttcaaatttcattgttctcc
acctgctgcatttattacctattcattgatagaagctcatttacttcggcgcaaactcaa
aaagttcaagctcgatcgtttattggaattgtcctgcaaaccttcttgcctatactttta
gtggttttggctttggtgacacttttgaagaagaacggaggatatgatcaagtggccaat
aatcttacgtttattttctcgaattttcatagtggtgttgcgagttcgtcgattcttc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ACGTATTGGTTTCTCGCCAACTTCT 572 33 460 Antisense
CCAACTTCTTCGCATTTATGATTTT 31 277 476 Antisense
AATTTCCTGAATATCCCGGATCCAG 558 173 511 Antisense
AAAGAGTTCTTCACAGAGCCCTTCT 166 121 580 Antisense
GACTATATGGTTACGATCTCTTCAT 304 373 634 Antisense
GATCTCTTCATTGCTAAACCTGGCG 555 417 648 Antisense
TTCAAATTTCATTGTTCTCCACCTG 33 687 680 Antisense
CACCTGCTGCATTTATTACCTATTC 687 201 699 Antisense
GAAGCTCATTTACTTCGGCGCAAAC 267 343 731 Antisense
TAATCTTACGTTTATTTTCTCGAAT 24 637 879 Antisense
GGTGTTGCGAGTTCGTCGATTCTTC 246 501 913 Antisense
Sequence Source Affymetrix Proprietary Database