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[188797_at] 7TM receptor

Description T21B4.7 /REP_DB=WormBase Gene ID /WP=CE16432 /TR=O18102 /GB=CAB03374.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=7TM receptor
Cluster 6grp_total > 33      4grp_total > 36      6grp_cgc > 80      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 41
1 2 3 4 range
A 51.5
(2)
P 		50.2
(1.8)
A 		27.6
(-3)
A 		56.1
(3)
A 		29
B 38.6
(-0)
A 		34.8
(-1.1)
A 		27.9
(-3)
A 		49.5
(3)
P 		22
C 37.9
(-0.7)
M 		63.4
(3)
A 		22.2
(-3)
A 		25.7
(-2.5)
A 		41
avr 42.7
(1.3) 		49.5
(3) 		25.9
(-3) 		43.8
(1.6) 		24

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 62
1 2 3 4 5 6 range
A 91.5
(3)
P 		32.8
(-2.7)
A 		58.5
(-0.2)
A 		39
(-2.1)
A 		36.7
(-2.3)
A 		29.7
(-3)
A 		62
B 38
(-3)
A 		52.3
(3)
P 		48.6
(1.4)
A 		51.5
(2.7)
M 		46.8
(0.7)
A 		44.1
(-0.4)
M 		14
C 43.4
(-1.2)
A 		54
(0.3)
P 		72.8
(3)
A 		45.2
(-0.9)
A 		30.3
(-3)
A 		43.2
(-1.2)
M 		43
avr 57.6
(2.3) 		46.4
(-0.7) 		60
(3) 		45.2
(-1) 		37.9
(-3) 		39
(-2.7) 		22
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 14
1 2 3 4 range
A 18.7
(3)
P 		10.9
(-1.1)
A 		7.2
(-3)
A 		8.2
(-2.5)
A 		12
B 12.3
(3)
A 		8.6
(-0.8)
A 		6.5
(-3)
A 		10.6
(1.2)
P 		6
C 12.5
(0.5)
M 		18.2
(3)
A 		7.7
(-1.5)
A 		4.3
(-3)
A 		14
avr 14.5
(3) 		12.6
(1.5) 		7.1
(-3) 		7.7
(-2.5) 		7

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 12
1 2 3 4 5 6 range
A 16.9
(3)
P 		11.7
(-0.2)
A 		12.7
(0.4)
A 		9.9
(-1.3)
A 		11.1
(-0.6)
A 		7.2
(-3)
A 		10
B 13.2
(-1.8)
A 		17.4
(1.7)
P 		11.8
(-3)
A 		13.6
(-1.5)
M 		19
(3)
A 		16.5
(0.9)
M 		7
C 16.1
(1.5)
A 		16.5
(1.7)
P 		18.5
(3)
A 		9.1
(-3)
A 		9.8
(-2.6)
A 		14.4
(0.4)
M 		9
avr 15.4
(3) 		15.2
(2.7) 		14.3
(1.5) 		10.9
(-3) 		13.3
(0.2) 		12.7
(-0.6) 		5
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188797_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3023
Sequence Type Exemplar sequence
Representative Public ID T21B4.7 NCBI
Target Description T21B4.7 /REP_DB=WormBase Gene ID /WP=CE16432 /TR=O18102 /GB=CAB03374.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=7TM receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064270(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_064270 NCBI Caenorhabditis elegans Serpentine Receptor, class H family member (srh-69) (srh-69) mRNA, complete cds. 11/11 None
SNAP00000006690 ENSEMBL cdna:SNAP chromosome:CEL140:II:12513535:12514618:-1 11/11 None
GENEFINDER00000006693 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:12513535:12514462:-1 11/11 None
T21B4.7 ENSEMBL cdna:known chromosome:CEL140:II:12513535:12514618:-1 gene:T21B4.7 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:12513531-12514615(-) 100.0 100.0
Public Domain and Genome References
Gene Title 7TM receptor
Gene Symbol srh-69
Ensembl T21B4.7
Entrez Gene 188676 Entrez gene
SwissProt O18102 EMBL-EBI
WormBase CE16432 Wormbase
Functional Annotations
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4930 G-protein coupled receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB03374 Hypothetical protein T21B4.7 [Caenorhabditis elegans] ref|NP_496671.1| Serpentine Receptor, class H family member (srh-69) [Caenorhabditis elegans] 0.0
blast CAB03374 Hypothetical protein T21B4.7 [Caenorhabditis elegans] ref|NP_496671.1| Serpentine Receptor, class H family member (srh-69) [Caenorhabditis elegans] 1.0E-157
blast CAB03376 Hypothetical protein T21B4.9 [Caenorhabditis elegans] ref|NP_496673.1| Serpentine Receptor, class H family member (srh-70) [Caenorhabditis elegans] 1.0E-102
blast CAD56599 Hypothetical protein T21B4.14 [Caenorhabditis elegans] ref|NP_496670.2| Serpentine Receptor, class H family member (srh-73) [Caenorhabditis elegans] 2.0E-88
Protein Domains
Database ID Description E-Value
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 1.0E-126
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 4.5E-123
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_496671.1 7 25-47,60-82,102-124,145-167,211-233,250-272,287-306
T21B4.7 7 25-47,60-82,102-124,145-167,211-233,250-272,287-306
SNAP00000006690 7 25-47,60-82,102-124,145-167,211-233,250-272,287-306
GENEFINDER00000006693 6 7-26,50-72,93-115,159-181,198-220,235-254
Sequence
Target Sequence 
>C. ELEGANS:188797_AT
aagttccgtttctcaataaatctgtatcgagttatttggattttcctgaacattcttggc
aacttcgcagttttcactccagtatttcttaatcttccggagcaaggaaaagctatactt
catttattgaaaacaataccctgccctaccaaaaaatactttctggaaccaagtgttgtg
ttcacccccggcacattttgggacacctacttaacatcatcgttcaagctgatattgtta
gccaccggcttacaagtactatttttctcctcctgctgtatatattacctattcgtgaaa
agcggaaaaatctcaatgtcaaatcaaactcggcgactacaaattcgatttttcatcgga
attatcattcaaacttttgttccaatcctgttggtcttaattccgtt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAGTTCCGTTTCTCAATAAATCTGT 283 155 415 Antisense
GAACATTCTTGGCAACTTCGCAGTT 258 351 462 Antisense
TTCGCAGTTTTCACTCCAGTATTTC 133 697 478 Antisense
CCAGTATTTCTTAATCTTCCGGAGC 60 273 493 Antisense
TGGAACCAAGTGTTGTGTTCACCCC 49 547 578 Antisense
CCCGGCACATTTTGGGACACCTACT 544 259 601 Antisense
GGGACACCTACTTAACATCATCGTT 46 495 614 Antisense
AGCTGATATTGTTAGCCACCGGCTT 531 81 641 Antisense
TACAAGTACTATTTTTCTCCTCCTG 602 641 665 Antisense
TTTCTCCTCCTGCTGTATATATTAC 689 671 678 Antisense
CAATCCTGTTGGTCTTAATTCCGTT 555 181 797 Antisense
Sequence Source Affymetrix Proprietary Database