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[188779_at] G-protein coupled receptor, srg family

Description F15A4.7 /REP_DB=WormBase Gene ID /WP=CE15844 /TR=O17820 /GB=CAB02949.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=7TM receptor
Cluster 6grp_total > 01      4grp_total > 19      6grp_cgc > 03      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 83
1 2 3 4 range
A 16.5
(-3)
A 		29.6
(1)
A 		36
(3)
A 		32.8
(2)
A 		20
B 24.3
(-0.5)
A 		36.3
(1.7)
A 		11
(-3)
A 		43.4
(3)
A 		32
C 39.5
(-0.8)
M 		21.2
(-2.1)
A 		8.7
(-3)
A 		91.8
(3)
P 		83
avr 26.8
(-1.7) 		29
(-1.3) 		18.6
(-3) 		56
(3) 		37

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 44
1 2 3 4 5 6 range
A 38.3
(1.8)
A 		25.1
(-0)
A 		3.8
(-3)
A 		6.8
(-2.6)
A 		47.1
(3)
A 		28.4
(0.4)
A 		43
B 19.9
(0.8)
A 		24.9
(2.1)
A 		28.5
(3)
A 		4.6
(-3)
A 		13.5
(-0.8)
A 		20.5
(1)
A 		24
C 20.2
(-1)
A 		47.4
(3)
A 		6.2
(-3)
A 		29.3
(0.4)
A 		19
(-1.1)
A 		6.4
(-3)
A 		41
avr 26.1
(1.1) 		32.5
(3) 		12.8
(-3) 		13.6
(-2.8) 		26.5
(1.2) 		18.4
(-1.3) 		20
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 13
1 2 3 4 range
A 6
(-1.4)
A 		6.4
(-0.9)
A 		9.4
(3)
A 		4.8
(-3)
A 		5
B 7.7
(1.6)
A 		9
(2.7)
A 		2.5
(-3)
A 		9.3
(3)
A 		7
C 13.1
(1.8)
M 		6.1
(-1.5)
A 		3
(-3)
A 		15.5
(3)
P 		13
avr 8.9
(1.8) 		7.2
(-0.3) 		5
(-3) 		9.9
(3) 		5

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 14
1 2 3 4 5 6 range
A 7.1
(-0.2)
A 		8.9
(0.6)
A 		0.8
(-3)
A 		1.7
(-2.6)
A 		14.2
(3)
A 		6.9
(-0.3)
A 		13
B 6.9
(1.8)
A 		8.3
(3)
A 		6.9
(1.8)
A 		1.2
(-3)
A 		5.5
(0.6)
A 		7.6
(2.4)
A 		7
C 7.5
(-0.3)
A 		14.5
(3)
A 		1.6
(-3)
A 		5.9
(-1)
A 		6.1
(-0.9)
A 		2.1
(-2.8)
A 		13
avr 7.2
(0.4) 		10.6
(3) 		3.1
(-2.8) 		2.9
(-3) 		8.6
(1.4) 		5.5
(-1) 		8
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188779_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3953
Sequence Type Exemplar sequence
Representative Public ID F15A4.7 NCBI
Target Description F15A4.7 /REP_DB=WormBase Gene ID /WP=CE15844 /TR=O17820 /GB=CAB02949.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=7TM receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064258(9)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_064258 NCBI Caenorhabditis elegans Serpentine Receptor, class G (gamma) family member (srg-17) (srg-17) mRNA, complete cds. 9/11 None
GENEFINDER00000042558 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:12471380:12475137:1 9/11 None
F15A4.7 ENSEMBL cdna:known chromosome:CEL140:II:12473609:12475137:1 gene:F15A4.7 9/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000042551 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:12473605-12475134(+) 100.0 100.0
Public Domain and Genome References
Gene Title G-protein coupled receptor, srg family
Gene Symbol srg-17
Ensembl F15A4.7
Entrez Gene 184514 Entrez gene
SwissProt O17820 EMBL-EBI
WormBase CE33051 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7165 signal transduction inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4888 transmembrane receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB02949 Hypothetical protein F15A4.7 [Caenorhabditis elegans] ref|NP_496659.2| Serpentine Receptor, class G (gamma) family member (srg-17) [Caenorhabditis elegans] sp|O17820|SRG17_CAEEL Serpentine receptor class gamma-17 (Protein srg-17) 0.0
blast CAB02949 Hypothetical protein F15A4.7 [Caenorhabditis elegans] ref|NP_496659.2| Serpentine Receptor, class G (gamma) family member (srg-17) [Caenorhabditis elegans] sp|O17820|SRG17_CAEEL Serpentine receptor class gamma-17 (Protein srg-17) 1.0E-120
blast CAE73524 Hypothetical protein CBG20987 [Caenorhabditis briggsae] 1.0E-101
blast CAE73525 Hypothetical protein CBG20988 [Caenorhabditis briggsae] 2.0E-79
blast CAE73524 Hypothetical protein CBG20987 [Caenorhabditis briggsae] 1.0E-65
blast CAE73525 Hypothetical protein CBG20988 [Caenorhabditis briggsae] 5.0E-56
Protein Domains
Database ID Description E-Value
Pfam IPR003582 EMBL-EBI Metridin-like ShK toxin 1.5E-15
Pfam IPR003582 EMBL-EBI Metridin-like ShK toxin 0.0057
Pfam IPR000609 EMBL-EBI Integral membrane protein Srg, nematode type 1.0E-54
Pfam IPR000609 EMBL-EBI Integral membrane protein Srg, nematode type 1.2E-86
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_496659.2 7 26-48,61-83,88-110,152-174,197-219,235-257,267-289
F15A4.7 7 26-48,61-83,88-110,152-174,197-219,235-257,267-289
GENEFINDER00000042558 4 167-189,212-234,250-272,282-304
Sequence
Target Sequence 
>C. ELEGANS:188779_AT
gaatgtcatgtgtcctgatgccagcgacatataaccagttttggaacaaaatcacaccaa
ttgctagttttattatgctaattctcccgtttgccggtctctggaacattatgatatctc
aagttattgcatcaagtgtacgcggtggatttggggtggattatataaaagcagcttcac
tgtcactgttccagtccatctgcatcctgactgctttgggcttcacaatagtttgcacct
ctgtaacattttacaaactagcatgtctatcagatcgtgtacgatcaattgaaagatcgc
tttgttttacgagcatctcgatttcctgcacatttttactggtcgccggtactcagctga
cttttgctacatgcgctagctgcaaaactgatgctatgtatattctacaatttcttgcat
ttgacactttcaatgttgggttagtttttttccacctcttcatttcaaata

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAATGTCATGTGTCCTGATGCCAGC 275 331 407 Antisense
GTTTGCCGGTCTCTGGAACATTATG 564 449 495 Antisense
GTGTACGCGGTGGATTTGGGGTGGA 203 487 542 Antisense
AAAAGCAGCTTCACTGTCACTGTTC 96 133 573 Antisense
GGGCTTCACAATAGTTTGCACCTCT 619 491 624 Antisense
GATCGCTTTGTTTTACGAGCATCTC 592 417 701 Antisense
TTACGAGCATCTCGATTTCCTGCAC 623 681 713 Antisense
TTCCTGCACATTTTTACTGGTCGCC 454 699 729 Antisense
CCGGTACTCAGCTGACTTTTGCTAC 234 265 752 Antisense
GACTTTTGCTACATGCGCTAGCTGC 191 371 765 Antisense
TTTTTCCACCTCTTCATTTCAAATA 40 675 853 Antisense
Sequence Source Affymetrix Proprietary Database