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[188763_at] tyrosinase

Description Y44E3B.2 /REP_DB=WormBase Gene ID /WP=CE18391 /TR=O76708 /GB=AAK21515.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=tyrosinase
Cluster 6grp_total > 68      4grp_total > 05      6grp_total_sub > Increase      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 277
1 2 3 4 range
A 97
(-0.8)
A 		8.6
(-3)
A 		10
(-3)
A 		252
(3)
P 		243
B 167.5
(0.5)
A 		3.7
(-3)
A 		6.4
(-2.9)
A 		280.9
(3)
P 		277
C 114.9
(0.3)
A 		46.6
(-1.8)
A 		7.6
(-3)
A 		202.9
(3)
P 		195
avr 126.5
(-0) 		19.6
(-2.7) 		8
(-3) 		245.3
(3) 		237

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 513
1 2 3 4 5 6 range
A 240.8
(-0.6)
A 		144.2
(-2.2)
A 		106.8
(-2.8)
A 		96.5
(-3)
A 		125.3
(-2.5)
P 		456.9
(3)
P 		360
B 206
(-1.1)
P 		202.9
(-1.1)
M 		42.3
(-3)
A 		116.3
(-2.1)
A 		162.8
(-1.6)
P 		555.4
(3)
P 		513
C 254.2
(-0.7)
M 		139.1
(-2.6)
A 		128.9
(-2.7)
A 		111
(-3)
A 		173.2
(-2)
P 		492.3
(3)
P 		381
avr 233.7
(-0.9) 		162.1
(-2) 		92.7
(-3) 		107.9
(-2.8) 		153.8
(-2.1) 		501.5
(3) 		409
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 59
1 2 3 4 range
A 35.3
(2.7)
A 		1.9
(-3)
A 		2.6
(-2.9)
A 		36.9
(3)
P 		35
B 53.4
(2.3)
A 		0.9
(-3)
A 		1.5
(-2.9)
A 		59.9
(3)
P 		59
C 38
(3)
A 		13.4
(-1.2)
A 		2.7
(-3)
A 		34.2
(2.4)
P 		35
avr 42.2
(2.8) 		5.4
(-2.6) 		2.3
(-3) 		43.7
(3) 		41

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 197
1 2 3 4 5 6 range
A 44.4
(-1.6)
A 		51.3
(-1.1)
A 		23.2
(-3)
A 		24.5
(-2.9)
A 		37.8
(-2)
P 		111.2
(3)
P 		88
B 71.7
(-1.1)
P 		67.6
(-1.3)
M 		10.3
(-3)
A 		30.8
(-2.4)
A 		66.1
(-1.3)
P 		207.1
(3)
P 		197
C 94.2
(0)
M 		42.4
(-2.2)
A 		32.8
(-2.6)
A 		22.3
(-3)
A 		56
(-1.6)
P 		164.8
(3)
P 		143
avr 70.1
(-0.9) 		53.8
(-1.6) 		22.1
(-3) 		25.9
(-2.8) 		53.3
(-1.7) 		161
(3) 		139
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188763_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.122
Sequence Type Exemplar sequence
Representative Public ID Y44E3B.2 NCBI
Target Description Y44E3B.2 /REP_DB=WormBase Gene ID /WP=CE18391 /TR=O76708 /GB=AAK21515.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=tyrosinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_058730(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_058730 NCBI Caenorhabditis elegans Y44E3B.2 (tyrosinase) mRNA, complete cds. 11/11 None
GENEFINDER00000016551 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:3261394:3264111:1 11/11 None
SNAP00000016548 ENSEMBL cdna:SNAP chromosome:CEL140:I:3261443:3264107:1 11/11 None
Y44E3B.2 ENSEMBL cdna:known chromosome:CEL140:I:3261394:3264111:1 gene:Y44E3B.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:3261393-3264111(+) 100.0 100.0
Public Domain and Genome References
Gene Title tyrosinase
Ensembl Y44E3B.2
Entrez Gene 189907 Entrez gene
SwissProt O76708 EMBL-EBI
WormBase CE18391 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8152 metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
16491 oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAK21515 Hypothetical protein Y44E3B.2 [Caenorhabditis elegans] ref|NP_491131.1| Y44E3B.2 [Caenorhabditis elegans] 0.0
blast CAE68995 Hypothetical protein CBG14982 [Caenorhabditis briggsae] 0.0
blast CAB04594 Hypothetical protein K08E3.1 [Caenorhabditis elegans] ref|NP_499836.1| K08E3.1 [Caenorhabditis elegans] 1.0E-76
Protein Domains
Database ID Description E-Value
Pfam IPR002227 EMBL-EBI Tyrosinase 6.9E-7
Pfam IPR002227 EMBL-EBI Tyrosinase 6.9E-7
Sequence
Target Sequence 
>C. ELEGANS:188763_AT
gggctaccatgccattatcgacgtgccccatgaaccatactcttgacgctcgaatgcttg
aattctcccatgattatgtgcactttttcgtcaacggtgacatgagcaaatcgtactcgt
catcgaatgatgtatgtttcgtgtatcatcacggaatgatcgattggatttttgagcact
ggcgccagaatatgcagagccgagaggaacggaaaactgagtacccaaagagtgatgaaa
gatgcttcccgttctggcataatggcgataattcgatgcctttgttgcagcctctgaaaa
acaaggacgcgttatcaaatgggtacacagataacatgtatgaatactatccgaggccaa
cttgcaccagagaaaaccccgattgtgattctccttatctattctgctacattcctccaa
ataacgagcatccgccgagctg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGGCTACCATGCCATTATCGACGTG 317 493 584 Antisense
GACGCTCGAATGCTTGAATTCTCCC 400 381 628 Antisense
GAATTCTCCCATGATTATGTGCACT 215 325 643 Antisense
GTGCACTTTTTCGTCAACGGTGACA 259 481 661 Antisense
GATTGGATTTTTGAGCACTGGCGCC 90 435 745 Antisense
CTTCCCGTTCTGGCATAATGGCGAT 299 219 828 Antisense
TAATTCGATGCCTTTGTTGCAGCCT 587 627 852 Antisense
AATACTATCCGAGGCCAACTTGCAC 281 171 926 Antisense
AGAAAACCCCGATTGTGATTCTCCT 399 71 954 Antisense
TCCTTATCTATTCTGCTACATTCCT 589 591 975 Antisense
CAAATAACGAGCATCCGCCGAGCTG 491 191 1001 Antisense
Sequence Source Affymetrix Proprietary Database