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[188752_at] G-protein coupled receptor

Description D1022.6 /REP_DB=WormBase Gene ID /WP=CE02580 /GEN=sro-1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=G-protein coupled receptor
Cluster 6grp_highest_10_10 > 34      6grp_high1_10_10 > 32      4grp_highest_8_8 > 45      4grp_high_8_8 > 01      6grp_highest_nonorm > 80      6grp_total > 21      4grp_total > 15      6grp_highest_sub > 02_03      6grp_cgc > 44      6grp_high1_sub > 02_03      6grp_cgc_sub > 02      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 212
1 2 3 4 range
A 279.1
(2.6)
P 		159.7
(-2.8)
P 		154.2
(-3)
P 		287.2
(3)
P 		133
B 264.8
(2.4)
P 		136.7
(-3)
P 		139.3
(-2.9)
P 		278
(3)
P 		141
C 306.6
(3)
P 		94.8
(-3)
P 		148.7
(-1.5)
P 		288.7
(2.5)
P 		212
avr 283.5
(3) 		130.4
(-3) 		147.4
(-2.3) 		284.6
(3) 		154

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 123
1 2 3 4 5 6 range
A 289
(3)
P 		247.9
(0.9)
P 		289.2
(3)
P 		172
(-3)
P 		226.6
(-0.2)
P 		183.9
(-2.4)
P 		117
B 196.1
(-1.1)
P 		251.6
(3)
P 		206.4
(-0.3)
P 		188.2
(-1.6)
P 		171.3
(-2.9)
P 		169.4
(-3)
P 		82
C 166.2
(-3)
P 		260.9
(2.4)
P 		271
(3)
P 		220.7
(0.1)
P 		203.6
(-0.9)
P 		175.4
(-2.5)
P 		105
avr 217.1
(0.1) 		253.5
(2.8) 		255.5
(3) 		193.6
(-1.7) 		200.5
(-1.2) 		176.2
(-3) 		79
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 74
1 2 3 4 range
A 101.6
(3)
P 		34.7
(-3)
P 		40.3
(-2.5)
P 		42
(-2.3)
P 		67
B 84.5
(3)
P 		33.8
(-2.8)
P 		32.3
(-3)
P 		59.3
(0.1)
P 		52
C 101.5
(3)
P 		27.3
(-3)
P 		51.8
(-1)
P 		48.7
(-1.3)
P 		74
avr 95.9
(3) 		31.9
(-3) 		41.5
(-2.1) 		50
(-1.3) 		64

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 45
1 2 3 4 5 6 range
A 53.3
(-1.7)
P 		88.2
(3)
P 		63
(-0.4)
P 		43.6
(-3)
P 		68.4
(0.3)
P 		44.8
(-2.8)
P 		45
B 68.2
(0.2)
P 		83.8
(3)
P 		50.1
(-2.9)
P 		49.8
(-3)
P 		69.6
(0.5)
P 		63.2
(-0.6)
P 		34
C 61.6
(-0.1)
P 		79.6
(3)
P 		69
(1.2)
P 		44.4
(-3)
P 		65.9
(0.7)
P 		58.7
(-0.6)
P 		35
avr 61
(-0.6) 		83.9
(3) 		60.7
(-0.7) 		45.9
(-3) 		68
(0.5) 		55.6
(-1.5) 		38
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188752_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.5612
Sequence Type Exemplar sequence
Representative Public ID D1022.6 NCBI
Target Description D1022.6 /REP_DB=WormBase Gene ID /WP=CE02580 /GEN=sro-1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=G-protein coupled receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063163(10)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063163 NCBI Caenorhabditis elegans Serpentine Receptor, class O (opsin) family member (sro-1) (sro-1) mRNA, complete cds. 10/11 None
SNAP00000004647 ENSEMBL cdna:SNAP chromosome:CEL140:II:7460038:7461513:-1 10/11 None
GENEFINDER00000004657 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:7460038:7463542:-1 10/11 None
D1022.6 ENSEMBL cdna:known chromosome:CEL140:II:7460038:7463542:-1 gene:D1022.6 10/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:7460034-7463539(-) 88.35 100.0
Public Domain and Genome References
Gene Title G-protein coupled receptor
Gene Symbol sro-1
Ensembl D1022.6
Entrez Gene 191958 Entrez gene
SwissProt Q18929 EMBL-EBI
WormBase CE36812 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7186 G-protein coupled receptor protein signaling pathway inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
1584 rhodopsin-like receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_495564 Serpentine Receptor, class O (opsin) family member (sro-1) [Caenorhabditis elegans] gb|AAB93339.2| Serpentine receptor, class o (opsin) protein 1 [Caenorhabditis elegans] 0.0
blast 2123261AU chemosensory receptor 0.0
blast 2123261AU chemosensory receptor 1.0E-173
blast CAE67532 Hypothetical protein CBG13055 [Caenorhabditis briggsae] 1.0E-159
Protein Domains
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_495564.2 7 51-73,93-112,127-149,169-191,227-249,287-309,319-341
D1022.6 7 51-73,93-112,127-149,169-191,227-249,287-309,319-341
SNAP00000004647 4 61-83,119-141,179-201,211-233
GENEFINDER00000004657 7 51-73,93-112,127-149,169-191,227-249,287-309,319-341
Sequence
Target Sequence 
>C. ELEGANS:188752_AT
ggtattccaaagccagaagtctgcacatgggctccaaaaaatcatgttggaaaagttgga
ctcggatgtctccttgtatcggttgtcccgttcttcgcctactccattgtctgcctgaat
ccaatgaaatcaaatttccatcaaattcattatattgtgatacctgtaattgtcagtcga
gtaagtactcttctcaatccaattttctacgtgtggctcaatcctgaaataatcccaatc
aacgagttcattgcaaaacgagcaaagcctcgtccacaacgaccaatgcccgtctcgttt
aatttcaggatttcaacaaaaaaaattgcctattttgctacagtttttcacaaaatttct
acgagattgaagtttttgaacttatatgttacaattaaaatcaaattttctgaattttta
cataaagattcgagctttttcagaaaaaaactaatcgccgatgtccctggaatgtctttc
cctatcctgacaccaacaattccccgccgacaacttccaaaaatcccgcctcatctggca
tcaccgtcgagaccaagtctcaatgattttctg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGTATTCCAAAGCCAGAAGTCTGCA 151 505 817 Antisense
GAAGTCTGCACATGGGCTCCAAAAA 672 335 832 Antisense
TTGGACTCGGATGTCTCCTTGTATC 107 709 872 Antisense
CTCCATTGTCTGCCTGAATCCAATG 614 235 918 Antisense
AGTACTCTTCTCAATCCAATTTTCT 49 63 1000 Antisense
AATTTTCTACGTGTGGCTCAATCCT 358 175 1017 Antisense
GCTCAATCCTGAAATAATCCCAATC 102 303 1032 Antisense
AAACGAGCAAAGCCTCGTCCACAAC 328 127 1072 Antisense
ATGCCCGTCTCGTTTAATTTCAGGA 622 41 1102 Antisense
AAAACTAATCGCCGATGTCCCTGGA 61 131 1263 Antisense
GAGACCAAGTCTCAATGATTTTCTG 144 395 1365 Antisense
Sequence Source Affymetrix Proprietary Database