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[188742_at] thioredoxin

Description B0024.9 /REP_DB=WormBase Gene ID /WP=CE05153 /TR=Q17424 /GB=CAA94881.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=thioredoxin
Cluster 6grp_highest_10_10 > 49      6grp_high1_10_10 > 94      4grp_highest_8_8 > 23      4grp_high_8_8 > 06      6grp_highest_nonorm > 64      6grp_total > 84      4grp_total > 02      6grp_highest_sub > 04_05_06      6grp_high1_sub > In      6grp_total_sub > Hat      6grp_rule_based > S5      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2191
1 2 3 4 range
A 719.9
(-2.7)
P 		638.8
(-3)
P 		653.1
(-2.9)
P 		2326.4
(3)
P 		1688
B 804
(-2.5)
P 		629.2
(-3)
P 		689.7
(-2.8)
P 		2648.5
(3)
P 		2019
C 673
(-2.8)
P 		590.8
(-3)
P 		762.5
(-2.5)
P 		2781.8
(3)
P 		2191
avr 732.3
(-2.7) 		619.6
(-3) 		701.8
(-2.7) 		2585.6
(3) 		1966

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 539
1 2 3 4 5 6 range
A 570.2
(-3)
P 		750.2
(-0.5)
P 		954.3
(2.3)
P 		1008.7
(3)
P 		944.8
(2.1)
P 		895.7
(1.5)
P 		439
B 586.5
(-3)
P 		874
(0.3)
P 		924.4
(0.9)
P 		1109.5
(3)
P 		1096.5
(2.9)
P 		1063.8
(2.5)
P 		523
C 685.8
(-2.4)
P 		816.6
(0.1)
P 		652.8
(-3)
P 		876.6
(1.2)
P 		971.7
(3)
P 		875.8
(1.2)
P 		319
avr 614.2
(-3) 		813.6
(0.1) 		843.8
(0.5) 		998.3
(2.9) 		1004.3
(3) 		945.1
(2.1) 		390
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 426
1 2 3 4 range
A 262.1
(0.7)
P 		138.7
(-3)
P 		170.7
(-2)
P 		340.5
(3)
P 		202
B 256.4
(-1.5)
P 		155.4
(-3)
P 		159.8
(-2.9)
P 		564.4
(3)
P 		409
C 222.8
(-1.9)
P 		169.9
(-3)
P 		265.8
(-1.1)
P 		469.1
(3)
P 		299
avr 247.1
(-1.2) 		154.7
(-3) 		198.8
(-2.1) 		458
(3) 		303

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 340
1 2 3 4 5 6 range
A 105.1
(-3)
P 		266.8
(2.4)
P 		207.8
(0.4)
P 		255.8
(2)
P 		285.1
(3)
P 		218.1
(0.8)
P 		180
B 204.1
(-3)
P 		290.9
(-0.8)
P 		224.5
(-2.5)
P 		293.9
(-0.8)
P 		445.5
(3)
P 		396.7
(1.8)
P 		241
C 254.2
(0.6)
P 		249.2
(0.4)
P 		166.2
(-3)
P 		176.3
(-2.6)
P 		314.4
(3)
P 		293.2
(2.1)
P 		148
avr 187.8
(-3) 		269
(0) 		199.5
(-2.6) 		242
(-1) 		348.3
(3) 		302.7
(1.3) 		161
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188742_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11431
Sequence Type Exemplar sequence
Representative Public ID B0024.9 NCBI
Target Description B0024.9 /REP_DB=WormBase Gene ID /WP=CE05153 /TR=Q17424 /GB=CAA94881.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=thioredoxin
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073250(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073250 NCBI Caenorhabditis elegans B0024.9 (thioredoxin) mRNA, complete cds. 11/11 A 
SNAP00000027135 ENSEMBL cdna:SNAP chromosome:CEL140:V:10317251:10317790:1 11/11 None
GENEFINDER00000027149 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:10317106:10317790:1 11/11 None
B0024.9.1 ENSEMBL cdna:known chromosome:CEL140:V:10317221:10317934:1 gene:B0024.9 11/11 A 
B0024.9.2 ENSEMBL cdna:known chromosome:CEL140:V:10317251:10317899:1 gene:B0024.9 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:10317328-10317790(+) 100.0 100.0
Public Domain and Genome References
Gene Title thioredoxin
Ensembl B0024.9
Entrez Gene 179434 Entrez gene
SwissProt Q17424 EMBL-EBI
WormBase CE05153 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1587612_AT similar to Thioredoxin, mitochondrial precursor (Mt-Trx) (MTRX) (Thioredoxin-2) cfa
CANINE:1586746_AT similar to Thioredoxin, mitochondrial precursor (Mt-Trx) (MTRX) (Thioredoxin-2) cfa
CANINE_2:CFA.10007.1.A1_S_AT similar to Thioredoxin, mitochondrial precursor (Mt-Trx) (MTRX) (Thioredoxin-2) cfa
CANINE_2:CFA.7630.1.S1_S_AT similar to Thioredoxin, mitochondrial precursor (Mt-Trx) (MTRX) (Thioredoxin-2) cfa
DROSOPHILA_2:1641655_AT dm
DROSGENOME1:148040_AT dm
HG-U133_PLUS_2:209078_S_AT thioredoxin 2 hs
HG-U133A:209078_S_AT thioredoxin 2 hs
HG-U133A_2:209078_S_AT thioredoxin 2 hs
HU35KSUBA:AA393581_AT thioredoxin 2 hs
HUGENEFL:U78678_AT thioredoxin 2 hs
U133_X3P:G9280552_3P_A_AT thioredoxin 2 hs
U133_X3P:HS.211929.0.S2_3P_AT thioredoxin 2 hs
HG-U133A_2:209077_AT thioredoxin 2 hs
HG-FOCUS:209077_AT thioredoxin 2 hs
HG-U133_PLUS_2:209077_AT thioredoxin 2 hs
HG-U133A:209077_AT thioredoxin 2 hs
HG-U95AV2:32852_AT thioredoxin 2 hs
MOUSE430_2:1421557_X_AT thioredoxin 2 mm
MOE430A:1421557_X_AT thioredoxin 2 mm
MOUSE430A_2:1421557_X_AT thioredoxin 2 mm
MU11KSUBA:U85089_S_AT thioredoxin 2 mm
MG-U74AV2:98130_AT thioredoxin 2 mm
MOE430A:1452782_A_AT thioredoxin 2 mm
MOUSE430A_2:1452782_A_AT thioredoxin 2 mm
MOUSE430_2:1452782_A_AT thioredoxin 2 mm
MOE430A:1455640_A_AT thioredoxin 2 mm
MOUSE430A_2:1455640_A_AT thioredoxin 2 mm
MOUSE430_2:1455640_A_AT thioredoxin 2 mm
MG-U74CV2:136451_AT Thioredoxin 2 (Txn2), mRNA mm
MU19KSUBB:TC30347_S_AT Thioredoxin 2 (Txn2), mRNA mm
RG-U34A:U73525_AT thioredoxin 2 rn
RAE230A:1398844_AT thioredoxin 2 rn
RAT230_2:1398844_AT thioredoxin 2 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6118 electron transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5489 electron transporter activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA94881 Hypothetical protein B0024.9 [Caenorhabditis elegans] ref|NP_505651.1| B0024.9 [Caenorhabditis elegans] sp|Q17424|THIO2_CAEEL Probable thioredoxin B0024.9 3.0E-63
blast CAA94881 Hypothetical protein B0024.9 [Caenorhabditis elegans] ref|NP_505651.1| B0024.9 [Caenorhabditis elegans] sp|Q17424|THIO2_CAEEL Probable thioredoxin B0024.9 7.0E-63
blast CAE64788 Hypothetical protein CBG09581 [Caenorhabditis briggsae] 1.0E-61
blast CAE64788 Hypothetical protein CBG09581 [Caenorhabditis briggsae] 2.0E-61
blast CAE64788 Hypothetical protein CBG09581 [Caenorhabditis briggsae] 1.0E-51
Protein Domains
Database ID Description E-Value
Pfam IPR006662 EMBL-EBI Thioredoxin type domain 1.2E-24
Pfam IPR006662 EMBL-EBI Thioredoxin type domain 1.2E-24
Pfam IPR006662 EMBL-EBI Thioredoxin type domain 1.2E-24
Sequence
Target Sequence 
>C. ELEGANS:188742_AT
gacacaattacgtcatttttctcacggcgcttctgttttcgacattgattctgttgaaga
tttcacagaaaaggtaattcaatcatcagttccagtcattgttgatttccacgcagaatg
gtgcggaccgtgccaggctttgggaccaagactcgaggaaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GACACAATTACGTCATTTTTCTCAC 131 367 15 Antisense
CAATTACGTCATTTTTCTCACGGCG 230 181 19 Antisense
GCGCTTCTGTTTTCGACATTGATTC 11 289 41 Antisense
GTTTTCGACATTGATTCTGTTGAAG 157 449 49 Antisense
CATTGATTCTGTTGAAGATTTCACA 9 217 57 Antisense
AAAAGGTAATTCAATCATCAGTTCC 71 133 83 Antisense
TCCAGTCATTGTTGATTTCCACGCA 117 589 105 Antisense
AGTCATTGTTGATTTCCACGCAGAA 311 61 108 Antisense
ATTTCCACGCAGAATGGTGCGGACC 281 17 119 Antisense
GTGCCAGGCTTTGGGACCAAGACTC 278 475 144 Antisense
GCTTTGGGACCAAGACTCGAGGAAA 624 303 151 Antisense
Sequence Source Affymetrix Proprietary Database