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[188733_at] Bromodomain

Description C01H6.7 /REP_DB=WormBase Gene ID /WP=CE05190 /TR=Q17581 /GB=CAA95779.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=Bromodomain
Cluster 6grp_highest_10_10 > 65      6grp_high1_10_10 > 56      4grp_highest_8_8 > 47      4grp_high_8_8 > 11      6grp_highest_nonorm > 84      6grp_total > 56      4grp_total > 13      6grp_cgc > 36      6grp_high1_sub > Cu      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 432
1 2 3 4 range
A 770.1
(1)
P 		709.4
(-0.2)
P 		572
(-3)
P 		865.7
(3)
P 		294
B 700.5
(-0.9)
P 		655.5
(-1.6)
P 		552.2
(-3)
P 		984.2
(3)
P 		432
C 806
(2)
P 		560
(-3)
P 		637.6
(-1.4)
P 		854.8
(3)
P 		295
avr 758.9
(0.3) 		641.6
(-2) 		587.3
(-3) 		901.6
(3) 		314

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 510
1 2 3 4 5 6 range
A 572.8
(0.1)
P 		725.6
(2.4)
P 		547.5
(-0.3)
P 		566.6
(0)
P 		359.8
(-3)
P 		769.5
(3)
P 		410
B 747.3
(1.5)
P 		563.1
(-1.1)
P 		636
(-0.1)
P 		489.9
(-2.1)
P 		427.2
(-3)
P 		854.9
(3)
P 		428
C 651.2
(0.5)
P 		602.3
(-0)
P 		706.4
(1.2)
P 		633.9
(0.3)
P 		351
(-3)
P 		860.9
(3)
P 		510
avr 657.1
(0.7) 		630.3
(0.4) 		630
(0.3) 		563.5
(-0.5) 		379.3
(-3) 		828.4
(3) 		449
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 154
1 2 3 4 range
A 280.4
(3)
P 		154
(-1.9)
P 		149.5
(-2.1)
P 		126.7
(-3)
P 		154
B 223.4
(3)
P 		161.9
(-0.9)
P 		128
(-3)
P 		209.7
(2.1)
P 		95
C 266.8
(3)
P 		161
(-2.2)
P 		222.2
(0.8)
P 		144.1
(-3)
P 		123
avr 256.9
(3) 		159
(-3) 		166.6
(-2.5) 		160.2
(-2.9) 		98

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 213
1 2 3 4 5 6 range
A 105.6
(-3)
P 		258.1
(3)
P 		119.2
(-2.5)
P 		143.7
(-1.5)
P 		108.6
(-2.9)
P 		187.3
(0.2)
P 		153
B 260
(1.1)
P 		187.4
(-1.2)
P 		154.4
(-2.2)
P 		129.8
(-3)
P 		173.5
(-1.6)
P 		318.8
(3)
P 		189
C 241.4
(1.4)
P 		183.8
(-0.6)
P 		179.8
(-0.7)
P 		127.5
(-2.5)
P 		113.6
(-3)
P 		288.2
(3)
P 		175
avr 202.3
(0.2) 		209.8
(0.5) 		151.1
(-2.1) 		133.7
(-2.9) 		131.9
(-3) 		264.8
(3) 		133
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188733_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1150
Sequence Type Exemplar sequence
Representative Public ID C01H6.7 NCBI
Target Description C01H6.7 /REP_DB=WormBase Gene ID /WP=CE05190 /TR=Q17581 /GB=CAA95779.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=Bromodomain
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059640(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059640 NCBI Caenorhabditis elegans C01H6.7 (Bromodomain) mRNA, complete cds. 11/11 None
SNAP00000008121 ENSEMBL cdna:SNAP chromosome:CEL140:I:7232965:7235673:1 11/11 None
GENEFINDER00000008132 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:7232965:7235673:1 11/11 None
C01H6.7 ENSEMBL cdna:known chromosome:CEL140:I:7232909:7235883:1 gene:C01H6.7 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:7232895-7235604(+) 100.0 100.0
Public Domain and Genome References
Gene Title Bromodomain
Gene Symbol tag-298
Ensembl C01H6.7
Entrez Gene 172461 Entrez gene
SwissProt Q17581 EMBL-EBI
WormBase CE05190 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1604887_AT similar to bromodomain containing 7 cfa
CANINE:1592319_S_AT similar to bromodomain containing 7 cfa
CANINE_2:CFAAFFX.15480.1.S1_S_AT similar to bromodomain containing 7 cfa
DROSOPHILA_2:1632589_AT dm
DROSGENOME1:154113_AT dm
CHICKEN:GGA.6338.1.S1_S_AT bromodomain containing 7 gga
CHICKEN:GGA.6338.2.S1_AT bromodomain containing 7 gga
HU35KSUBA:R76185_S_AT bromodomain containing 7 hs
HU35KSUBA:RC_AA292066_I_AT bromodomain containing 7 hs
U133_X3P:HS.279762.1.S1_3P_A_AT bromodomain containing 7 hs
U133_X3P:HS.279762.0.A1_3P_A_AT bromodomain containing 7 hs
HG-U133A_2:221776_S_AT bromodomain containing 7 hs
HG-FOCUS:221776_S_AT bromodomain containing 7 hs
HG-U133_PLUS_2:221776_S_AT bromodomain containing 7 hs
HG-U133A:221776_S_AT bromodomain containing 7 hs
HG-U133_PLUS_2:222737_S_AT bromodomain containing 7 hs
HG-U133B:222737_S_AT bromodomain containing 7 hs
HG-U95E:91003_AT bromodomain containing 7 hs
HG-U133_PLUS_2:238545_AT Bromodomain containing 7 hs
HG-U133B:238545_AT Bromodomain containing 7 hs
HG-U95C:63521_AT Bromodomain containing 7 hs
MG-U74AV2:100544_AT bromodomain containing 7 mm
MU11KSUBA:AA620184_G_AT bromodomain containing 7 mm
MU11KSUBA:AA620184_AT bromodomain containing 7 mm
MG-U74AV2:100543_S_AT bromodomain containing 7 mm
MG-U74AV2:161290_R_AT bromodomain containing 7 mm
MOE430A:1448521_AT bromodomain containing 7 mm
MOUSE430A_2:1448521_AT bromodomain containing 7 mm
MOUSE430_2:1448521_AT bromodomain containing 7 mm
MOE430B:1436469_AT Bromodomain containing 7 (Brd7), mRNA mm
MOUSE430_2:1436469_AT Bromodomain containing 7 (Brd7), mRNA mm
MU19KSUBC:TC40148_AT Bromodomain containing 7 (Brd7), mRNA mm
RG-U34C:RC_AI137298_AT bromodomain containing 7 (predicted) rn
RAE230A:1399055_AT bromodomain containing 7 (predicted) rn
RAT230_2:1399055_AT bromodomain containing 7 (predicted) rn
Protein Similarities
Method ID Description E-Value
blast CAA95779 Hypothetical protein C01H6.7 [Caenorhabditis elegans] ref|NP_492041.1| C01H6.7 [Caenorhabditis elegans] 0.0
blast CAE74243 Hypothetical protein CBG21928 [Caenorhabditis briggsae] 0.0
blast XP_394586 PREDICTED: similar to CG7154-PA [Apis mellifera] 3.0E-53
Protein Domains
Database ID Description E-Value
Pfam IPR001487 EMBL-EBI Bromodomain 2.6E-36
Sequence
Target Sequence 
>C. ELEGANS:188733_AT
tgcgtcgatttgttggagattgccccgagttctcagagattattggaagcttattggata
cacttactgacggcgagcactcgaaaacaatgaaagaacttgaaaatgcagggaaagaag
ttaaggaggaagttgataatgatgagtacaagaatgaaactgttctttccttgattgatg
acgtcagttccatctccaacttgggtattgaaactggatttttgaatgacattcgccagc
aagttctagttccagctgtggaaagcaacattgagaacaatataccggaattcatgaatg
aagtgaatcatatgaatgttcaacaacagctcaatcactctggacaaaaagttaaagatc
ttgctcatatccaagaacatcgtcttgtccagcaaccacctcctatgatcatgtccgtac
aaggcgcaggacaaattgaacaaaagcttgctgagaatttgcagcaacatttggctcatc
aaatgacaacacacgctgccccagaagcctttgtaaacga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGCGTCGATTTGTTGGAGATTGCCC 647 583 1328 Antisense
AGATTGCCCCGAGTTCTCAGAGATT 437 65 1344 Antisense
ATACACTTACTGACGGCGAGCACTC 304 25 1385 Antisense
GAATGAAACTGTTCTTTCCTTGATT 427 331 1479 Antisense
TGATGACGTCAGTTCCATCTCCAAC 259 567 1503 Antisense
CATTCGCCAGCAAGTTCTAGTTCCA 320 217 1557 Antisense
ACAACAGCTCAATCACTCTGGACAA 192 113 1650 Antisense
TGATCATGTCCGTACAAGGCGCAGG 114 565 1733 Antisense
TTTGCAGCAACATTTGGCTCATCAA 668 667 1785 Antisense
CATCAAATGACAACACACGCTGCCC 162 213 1804 Antisense
CTGCCCCAGAAGCCTTTGTAAACGA 185 233 1823 Antisense
Sequence Source Affymetrix Proprietary Database