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[188713_at] isomerase

Description Y17G9B.4 /REP_DB=WormBase Gene ID /WP=CE21394 /TR=Q9N579 /GB=AAF60445.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=isomerase
Cluster 6grp_total > 97      4grp_total > 27      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 52
1 2 3 4 range
A 20.1
(-2.8)
A 		26.3
(-1.8)
A 		18.9
(-3)
A 		56.6
(3)
A 		38
B 18.1
(-1.4)
A 		22.2
(-0.5)
A 		10.6
(-3)
A 		39
(3)
A 		28
C 15.5
(-1.6)
A 		49.4
(3)
A 		4.7
(-3)
A 		16.8
(-1.4)
A 		45
avr 17.9
(-1.5) 		32.6
(1.9) 		11.4
(-3) 		37.5
(3) 		26

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 92
1 2 3 4 5 6 range
A 13.3
(-2.7)
A 		10.2
(-3)
A 		21.9
(-2)
A 		9.7
(-3)
A 		62.3
(1.5)
A 		80.3
(3)
A 		71
B 8.9
(-2.9)
A 		7.7
(-3)
A 		10.6
(-2.8)
A 		68.3
(1)
A 		67
(0.9)
A 		99.3
(3)
A 		92
C 33.6
(-0.6)
A 		45.3
(0.7)
A 		24.3
(-1.7)
A 		13.3
(-3)
A 		41.1
(0.2)
A 		64.8
(3)
A 		52
avr 18.6
(-3) 		21.1
(-2.8) 		18.9
(-3) 		30.4
(-1.9) 		56.8
(0.6) 		81.5
(3) 		63
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 13
1 2 3 4 range
A 7.3
(1.2)
A 		5.7
(-1.6)
A 		4.9
(-3)
A 		8.3
(3)
A 		3
B 5.8
(0.4)
A 		5.5
(0.1)
A 		2.5
(-3)
A 		8.3
(3)
A 		6
C 5.1
(-1.3)
A 		14.2
(3)
A 		1.6
(-3)
A 		2.8
(-2.4)
A 		13
avr 6.1
(0.4) 		8.5
(3) 		3
(-3) 		6.5
(0.8) 		6

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 35
1 2 3 4 5 6 range
A 2.4
(-3)
A 		3.6
(-2.6)
A 		4.8
(-2.2)
A 		2.5
(-3)
A 		18.8
(2.8)
A 		19.5
(3)
A 		17
B 3.1
(-2.9)
A 		2.6
(-3)
A 		2.6
(-3)
A 		18.1
(-0.3)
A 		27.2
(1.3)
A 		37
(3)
A 		34
C 12.5
(0.1)
A 		13.8
(0.5)
A 		6.2
(-1.9)
A 		2.7
(-3)
A 		13.3
(0.3)
A 		21.7
(3)
A 		19
avr 6
(-2.6) 		6.7
(-2.4) 		4.5
(-3) 		7.8
(-2.1) 		19.8
(1.3) 		26.1
(3) 		22
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188713_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.10543
Sequence Type Exemplar sequence
Representative Public ID Y17G9B.4 NCBI
Target Description Y17G9B.4 /REP_DB=WormBase Gene ID /WP=CE21394 /TR=Q9N579 /GB=AAF60445.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=isomerase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_068231(10)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_068231 NCBI Caenorhabditis elegans Y17G9B.4 (isomerase) mRNA, complete cds. 10/11 None
SNAP00000043795 ENSEMBL cdna:SNAP chromosome:CEL140:IV:4752110:4753112:1 10/11 None
GENEFINDER00000043815 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:4752110:4753112:1 10/11 None
Y17G9B.4 ENSEMBL cdna:known chromosome:CEL140:IV:4752110:4753143:1 gene:Y17G9B.4 10/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:4752115-4753118(+) 100.0 100.0
Public Domain and Genome References
Gene Title isomerase
Ensembl Y17G9B.4
Entrez Gene 177245 Entrez gene
SwissProt Q9N579 EMBL-EBI
WormBase CE34606 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6457 protein folding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_500632 Y17G9B.4 [Caenorhabditis elegans] gb|AAF60445.3| Hypothetical protein Y17G9B.4 [Caenorhabditis elegans] 1.0E-141
blast NP_500632 Y17G9B.4 [Caenorhabditis elegans] gb|AAF60445.3| Hypothetical protein Y17G9B.4 [Caenorhabditis elegans] 1.0E-136
blast AAC47127 cyclophilin isoform 2 (cyp-2) 5.0E-24
blast CAB07303 Hypothetical protein ZK520.5 [Caenorhabditis elegans] ref|NP_499828.1| CYclophyliN family member (cyn-2) [Caenorhabditis elegans] sp|P52010|CYP2_CAEEL Peptidyl-prolyl cis-trans isomerase 2 (PPIase) (Rotamase) (Cyclophilin-2) pir||T27882 peptidylprolyl isomerase (EC 5.2.1.8) ZK520.5 [similarity] - Caenorhabditis elegans 7.0E-24
Protein Domains
Database ID Description E-Value
Pfam IPR002130 EMBL-EBI Peptidyl-prolyl cis-trans isomerase, cyclophilin type 6.3E-12
Pfam IPR002130 EMBL-EBI Peptidyl-prolyl cis-trans isomerase, cyclophilin type 6.4E-6
Pfam IPR002130 EMBL-EBI Peptidyl-prolyl cis-trans isomerase, cyclophilin type 6.3E-12
Pfam IPR002130 EMBL-EBI Peptidyl-prolyl cis-trans isomerase, cyclophilin type 6.4E-6
Sequence
Target Sequence 
>C. ELEGANS:188713_AT
tcggcagtgcatcgaagtcttccacgtgatgctcgtaaggattacttgtccagagttcgg
ggaaaagtcgaacatctctacaaagctattcaaggtaacaaaaaaccagaaatcaatttc
gaagtttcactggaagaagccaaactcgctgataaatatctaaaagatgcaaagaaactc
ttcaacgatatcgtcccaagaaccgcacaaaatttcgaatcttggtgcacaggagagaaa
cggggaaaatatggagagccgctgcacttaaaggaatgtgaaattaagatgattttaccc
ggttccgtcatcggttttggagattttgaagaaaattgtgaatacttcgatgatgaaaag
tcaaaagaaaatcactgcaaaaatgtcctttccatgaacattgacaaatcagaaaactca
tccgctccgttgttcaatatggaactctcagatggcgtcgaccgcgctggaaaagccatc
gtttttgggaaagttgtgatgggaaatcgtgtcattgagaaagttctccttgccggatcc
agagacggaattccagaacaaactgtgaaaatctcggactgcggg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCGGCAGTGCATCGAAGTCTTCCAC 186 607 49 Antisense
AGGATTACTTGTCCAGAGTTCGGGG 154 55 86 Antisense
AAGTCGAACATCTCTACAAAGCTAT 226 159 113 Antisense
GAAACTCTTCAACGATATCGTCCCA 524 357 222 Antisense
ATCGTCCCAAGAACCGCACAAAATT 692 33 238 Antisense
GGAGAGCCGCTGCACTTAAAGGAAT 249 519 301 Antisense
CATCCGCTCCGTTGTTCAATATGGA 490 211 467 Antisense
TATGGAACTCTCAGATGGCGTCGAC 520 655 486 Antisense
TCGACCGCGCTGGAAAAGCCATCGT 68 603 506 Antisense
CTCCTTGCCGGATCCAGAGACGGAA 377 235 574 Antisense
AACTGTGAAAATCTCGGACTGCGGG 174 143 609 Antisense
Sequence Source Affymetrix Proprietary Database