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[188712_s_at] 7TM chemoreceptor, srb family /// 7TM chemoreceptor, srb family

Description F37C12.16 /REP_DB=WormBase Gene ID /WP=CE26426 /GEN=srb-9 /TR=SW:P54143 /GB=AAC48304.2 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation
Cluster 6grp_total > 93      4grp_total > 03      6grp_cgc > 98      6grp_total_sub > Hat      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 66
1 2 3 4 range
A 4.4
(-2.8)
A 		7.9
(-2.5)
A 		2.4
(-3)
A 		66.5
(3)
A 		64
B 17.7
(0.6)
A 		1.3
(-3)
A 		3.7
(-2.5)
A 		28.5
(3)
A 		27
C 2.9
(-2.7)
A 		6.6
(-2.2)
A 		1
(-3)
A 		44.4
(3)
A 		43
avr 8.3
(-2.2) 		5.3
(-2.6) 		2.4
(-3) 		46.5
(3) 		44

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 25
1 2 3 4 5 6 range
A 4.4
(-2.6)
A 		3.3
(-2.9)
A 		13.9
(-0.1)
A 		2.8
(-3)
A 		26.1
(3)
A 		3.7
(-2.8)
A 		23
B 0.9
(-3)
A 		3
(2.3)
A 		2
(-0.3)
A 		2.5
(1)
A 		1.1
(-2.5)
A 		3.3
(3)
A 		2
C 4.3
(0.7)
A 		3.4
(-0.3)
A 		3
(-0.7)
A 		6.5
(3)
A 		4.7
(1.1)
A 		0.8
(-3)
A 		6
avr 3.2
(-2.6) 		3.2
(-2.6) 		6.3
(-0.2) 		3.9
(-2) 		10.6
(3) 		2.6
(-3) 		8
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 9
1 2 3 4 range
A 1.6
(-2.3)
A 		1.7
(-2.3)
A 		0.6
(-3)
A 		9.7
(3)
A 		9
B 5.7
(2.6)
A 		0.3
(-3)
A 		0.9
(-2.4)
A 		6.1
(3)
A 		6
C 0.9
(-2.6)
A 		1.9
(-1.7)
A 		0.4
(-3)
A 		7.5
(3)
A 		7
avr 2.7
(-1.3) 		1.3
(-2.4) 		0.6
(-3) 		7.8
(3) 		7

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 8
1 2 3 4 5 6 range
A 0.8
(-2.9)
A 		1.2
(-2.6)
A 		3
(-1.1)
A 		0.7
(-3)
A 		7.9
(3)
A 		0.9
(-2.8)
A 		7
B 0.3
(-3)
A 		1
(1.7)
A 		0.5
(-1.7)
A 		0.7
(-0.3)
A 		0.4
(-2.3)
A 		1.2
(3)
A 		1
C 1.6
(3)
A 		1
(0.2)
A 		0.8
(-0.7)
A 		1.3
(1.6)
A 		1.5
(2.5)
A 		0.3
(-3)
A 		1
avr 0.9
(-2.8) 		1.1
(-2.3) 		1.4
(-1.6) 		0.9
(-2.8) 		3.3
(3) 		0.8
(-3) 		3
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 188712_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6569
Sequence Type Exemplar sequence
Representative Public ID F37C12.16 NCBI
Target Description F37C12.16 /REP_DB=WormBase Gene ID /WP=CE26426 /GEN=srb-9 /TR=SW:P54143 /GB=AAC48304.2 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066168(11), NM_066169(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066168 NCBI Caenorhabditis elegans Serpentine Receptor, class B (beta) family member (srb-8) (srb-8) mRNA, complete cds. 11/11 None
NM_066169 NCBI Caenorhabditis elegans Serpentine Receptor, class B (beta) family member (srb-9) (srb-9) mRNA, complete cds. 11/11 None
GENEFINDER00000030612 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:7171893:7173616:1 11/11 None
GENEFINDER00000030606 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:7173931:7175618:-1 11/11 None
F37C12.15 ENSEMBL cdna:known chromosome:CEL140:III:7171781:7173514:1 gene:F37C12.15 11/11 None
F37C12.16 ENSEMBL cdna:known chromosome:CEL140:III:7173997:7175730:-1 gene:F37C12.16 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:7171778-7173512(+) 99.91 100.0
chrIII:7173994-7175728(-) 99.91 100.0
Public Domain and Genome References
Gene Title 7TM chemoreceptor, srb family
7TM chemoreceptor, srb family
Gene Symbol srb-8
srb-9
Ensembl F37C12.15
F37C12.16
Entrez Gene 191790 Entrez gene
191791 Entrez gene
SwissProt P83260 EMBL-EBI
WormBase CE26426 Wormbase
CE26426 Wormbase
Functional Annotations
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4888 transmembrane receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC48304 Serpentine receptor, class b (beta) protein 9 [Caenorhabditis elegans] gb|AAP68944.1| Serpentine receptor, class b (beta) protein 8 [Caenorhabditis elegans] ref|NP_498570.1| Serpentine Receptor, class B (beta) family member (srb-9) [Caenorhabditis elegans] ref|NP_498569.2| Serpentine Receptor, class B (beta) family member (srb-8) [Caenorhabditis elegans] sp|P83260|SRB8_CAEEL Serpentine receptor class beta-8/9 (Protein srb-8/Srb-9) 1.0E-163
blast T28830 hypothetical protein srb-8 and srb-9 - Caenorhabditis elegans prf||2123261W chemosensory receptor 1.0E-161
blast AAC48304 Serpentine receptor, class b (beta) protein 9 [Caenorhabditis elegans] gb|AAP68944.1| Serpentine receptor, class b (beta) protein 8 [Caenorhabditis elegans] ref|NP_498570.1| Serpentine Receptor, class B (beta) family member (srb-9) [Caenorhabditis elegans] ref|NP_498569.2| Serpentine Receptor, class B (beta) family member (srb-8) [Caenorhabditis elegans] sp|P83260|SRB8_CAEEL Serpentine receptor class beta-8/9 (Protein srb-8/Srb-9) 1.0E-149
blast T28830 hypothetical protein srb-8 and srb-9 - Caenorhabditis elegans prf||2123261W chemosensory receptor 1.0E-149
Protein Domains
Database ID Description E-Value
Pfam IPR002184 EMBL-EBI Integral membrane protein Srb, nematode type 1.0E-126
Pfam IPR002184 EMBL-EBI Integral membrane protein Srb, nematode type 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_498569.2 7 33-55,68-90,117-139,151-173,193-215,251-273,283-305
NP_498570.1 7 33-55,68-90,117-139,151-173,193-215,251-273,283-305
F37C12.15 7 33-55,68-90,117-139,151-173,193-215,251-273,283-305
F37C12.16 7 33-55,68-90,117-139,151-173,193-215,251-273,283-305
GENEFINDER00000030612 7 10-32,45-67,94-116,128-150,170-192,228-250,260-282
GENEFINDER00000030606 7 10-32,45-67,94-116,128-150,170-192,228-250,260-282
Sequence
Target Sequence 
>C. ELEGANS:188712_S_AT
aaactccagtaaagctgggcccaataatcacttttctcttaataataattgatttaacta
cggtttccatgatccatagaaactcaaattttgatgctggatcaatttcttttgttattt
ttccatctttggaagttggtttaacaatgatgaagtttttcataataattgttatattca
atgtgatcaactttttattcaatatcaaactcattagagataatgcaaaattgaaaagca
taaattccacattatccacaaaattccaactcgaagaagtatacttctcaacaatgtttg
tgattactgtagtgttttatcatgttgctttcttttgttcttatattattctagttttga
catttttagtcgttgggcctcttttatttaatccaatcgatgtatgggctggaaatggaa
ttttaatgactataatggccacttacaaccttgtta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAACTCCAGTAAAGCTGGGCCCAAT 309 127 455 Antisense
CTGGGCCCAATAATCACTTTTCTCT 707 239 469 Antisense
TTAACTACGGTTTCCATGATCCATA 235 661 508 Antisense
GATGCTGGATCAATTTCTTTTGTTA 131 415 547 Antisense
CATTATCCACAAAATTCCAACTCGA 704 215 704 Antisense
GAAGTATACTTCTCAACAATGTTTG 208 337 730 Antisense
GTAGTGTTTTATCATGTTGCTTTCT 151 457 763 Antisense
GTTGCTTTCTTTTGTTCTTATATTA 629 439 778 Antisense
GACATTTTTAGTCGTTGGGCCTCTT 54 371 813 Antisense
GGGCCTCTTTTATTTAATCCAATCG 575 491 829 Antisense
ATAATGGCCACTTACAACCTTGTTA 694 25 886 Antisense
Sequence Source Affymetrix Proprietary Database