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[188701_at] peptidase

Description F18A12.3 /REP_DB=WormBase Gene ID /WP=CE09456 /TR=O16792 /GB=AAB66075.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=peptidase
Cluster 6grp_total > 54      4grp_total > 34      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 17
1 2 3 4 range
A 3.1
(-3)
A 		15.1
(1.3)
A 		9.2
(-0.8)
A 		19.8
(3)
A 		17
B 3.7
(-3)
A 		9.2
(3)
A 		6.5
(0.1)
A 		5.9
(-0.6)
A 		6
C 4
(-2.6)
A 		16.8
(3)
A 		6.2
(-1.6)
A 		3
(-3)
A 		14
avr 3.6
(-3) 		13.7
(3) 		7.3
(-0.8) 		9.6
(0.6) 		10

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 9
1 2 3 4 5 6 range
A 5.7
(-0.6)
A 		8.2
(1.2)
A 		4.4
(-1.6)
A 		5.1
(-1)
A 		2.4
(-3)
A 		10.7
(3)
A 		8
B 2.6
(-3)
A 		4.1
(-1.5)
A 		8.8
(3)
A 		2.6
(-3)
A 		4
(-1.6)
A 		3.8
(-1.8)
A 		6
C 2
(-3)
A 		3.2
(-2.1)
A 		9.8
(3)
A 		6.1
(0.2)
A 		5.9
(0)
A 		4.3
(-1.2)
A 		8
avr 3.4
(-3) 		5.2
(-0.5) 		7.7
(3) 		4.6
(-1.3) 		4.1
(-2) 		6.3
(1) 		4
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 4
1 2 3 4 range
A 1.1
(-3)
A 		3.3
(3)
A 		2.4
(0.5)
A 		2.9
(1.9)
A 		2
B 1.2
(-3)
A 		2.3
(3)
A 		1.5
(-1.4)
A 		1.3
(-2.5)
A 		1
C 1.3
(-1.9)
A 		4.8
(3)
A 		2.2
(-0.6)
A 		0.5
(-3)
A 		4
avr 1.2
(-3) 		3.5
(3) 		2
(-0.9) 		1.6
(-2) 		2

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2
1 2 3 4 5 6 range
A 1
(-2.2)
A 		2.9
(3)
A 		1
(-2.2)
A 		1.3
(-1.4)
A 		0.7
(-3)
A 		2.6
(2.2)
A 		2
B 0.9
(-2.1)
A 		1.4
(-0)
A 		2.1
(3)
A 		0.7
(-3)
A 		1.6
(0.9)
A 		1.4
(-0)
A 		1
C 0.7
(-3)
A 		1
(-2)
A 		2.5
(3)
A 		1.2
(-1.3)
A 		1.9
(1)
A 		1.4
(-0.7)
A 		2
avr 0.9
(-3) 		1.8
(2.4) 		1.9
(3) 		1.1
(-1.8) 		1.4
(-0) 		1.8
(2.4) 		1
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188701_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.4162
Sequence Type Exemplar sequence
Representative Public ID F18A12.3 NCBI
Target Description F18A12.3 /REP_DB=WormBase Gene ID /WP=CE09456 /TR=O16792 /GB=AAB66075.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=peptidase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_062133(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_062133 NCBI Caenorhabditis elegans F18A12.3 (peptidase) mRNA, complete cds. 11/11 None
F18A12.3 ENSEMBL cdna:known chromosome:CEL140:II:3407142:3409769:1 gene:F18A12.3 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000014577 6/11 Cross Hyb Matching Probes None
GENEFINDER00000014588 6/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:3407140-3409794(+) 100.0 100.0
Public Domain and Genome References
Gene Title peptidase
Ensembl F18A12.3
Entrez Gene 184630 Entrez gene
SwissProt O16792 EMBL-EBI
WormBase CE35492 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8237 metallopeptidase activity inferred from electronic annotation QuickGO AmiGO
8270 zinc ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB66075 Hypothetical protein F18A12.3 [Caenorhabditis elegans] ref|NP_494534.2| F18A12.3 [Caenorhabditis elegans] 0.0
blast AAB66078 Hypothetical protein F18A12.6 [Caenorhabditis elegans] ref|NP_494532.1| F18A12.6 [Caenorhabditis elegans] 1.0E-90
blast AAB66076 Hypothetical protein F18A12.4 [Caenorhabditis elegans] ref|NP_494533.2| F18A12.4 [Caenorhabditis elegans] 2.0E-84
Protein Domains
Database ID Description E-Value
Pfam IPR000718 EMBL-EBI Peptidase M13, neprilysin 8.9E-17
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_494534.2 1 13-33
F18A12.3 1 13-33
Sequence
Target Sequence 
>C. ELEGANS:188701_AT
ttgatcctcctggaacattggacaaagagtttgaacacattgatttggactccaccgact
ccttctatagaatatctcaaaaacttcatcgactccgtactgaacaacaaatggagttca
tcgctggagagacccccatcagccctgtcgaaaatgttctagaagctgaatgtctgatag
atcaatatgataactacgctgatccggtctacggcaaaaagatgaatggaacacatacat
tcggagagatgattgctgattgggttggacatgaagtaacctggcgggcctataagaaga
tggatacttcaaaaatgcattcacttattggcctcaaggatatcaatatggatcagcttt
atttcagagttcagtcactgctatggtgcagttctcgtagtatgttgagcctggaagaag
ccctcgaagatgtacatccaacaaaacctttccgtgtcaatggagcatatgccaatatgc
cagagtttgcgaaagcattcagttgtcccgttggatcaccta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTGATCCTCCTGGAACATTGGACAA 295 705 1172 Antisense
GAACACATTGATTTGGACTCCACCG 219 353 1204 Antisense
TCCACCGACTCCTTCTATAGAATAT 405 589 1222 Antisense
AAAAACTTCATCGACTCCGTACTGA 24 131 1250 Antisense
CCCCATCAGCCCTGTCGAAAATGTT 384 261 1305 Antisense
TGATAACTACGCTGATCCGGTCTAC 449 563 1359 Antisense
GGACATGAAGTAACCTGGCGGGCCT 551 349 1438 Antisense
AAATGCATTCACTTATTGGCCTCAA 234 119 1484 Antisense
AGAAGCCCTCGAAGATGTACATCCA 67 75 1587 Antisense
CATCCAACAAAACCTTTCCGTGTCA 486 211 1606 Antisense
TTCAGTTGTCCCGTTGGATCACCTA 307 687 1669 Antisense
Sequence Source Affymetrix Proprietary Database