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[188681_at] Sec1 family

Description F43D9.3 /REP_DB=WormBase Gene ID /WP=CE00993 /TR=Q20364 /GB=CAA84704.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Sec1 family
Cluster 6grp_high1_10_10 > 49      4grp_highest_8_8 > 07      4grp_high_8_8 > 28      6grp_total > 19      4grp_total > 27      6grp_high1_sub > Cu      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 85
1 2 3 4 range
A 87.9
(-1.6)
P 		80
(-2.2)
P 		68.3
(-3)
P 		152.8
(3)
P 		85
B 82.8
(-2.8)
P 		129.7
(3)
P 		81.5
(-3)
P 		104.4
(-0.1)
P 		48
C 102.2
(1.2)
P 		117.3
(3)
P 		68.2
(-3)
P 		102.2
(1.2)
P 		49
avr 91
(-0.7) 		109
(1.6) 		72.7
(-3) 		119.8
(3) 		47

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 61
1 2 3 4 5 6 range
A 91.3
(2.8)
M 		43.5
(-2.2)
A 		35.6
(-3)
P 		73.5
(1)
P 		67.5
(0.3)
P 		93.1
(3)
P 		58
B 89.7
(3)
A 		50.6
(-1.1)
A 		49.5
(-1.2)
A 		68.8
(0.8)
P 		80
(2)
P 		31.8
(-3)
P 		58
C 84.5
(3)
P 		54.1
(-1.4)
P 		43.5
(-3)
A 		64.3
(0)
P 		71.3
(1.1)
P 		65.1
(0.2)
P 		41
avr 88.5
(3) 		49.4
(-2.1) 		42.9
(-3) 		68.9
(0.4) 		72.9
(0.9) 		63.3
(-0.3) 		46
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 17
1 2 3 4 range
A 32
(3)
P 		17.4
(-3)
P 		17.8
(-2.8)
P 		22.4
(-0.9)
P 		15
B 26.4
(0.4)
P 		32
(3)
P 		18.9
(-3)
P 		22.2
(-1.5)
P 		13
C 33.8
(3)
P 		33.7
(3)
P 		23.8
(-0.6)
P 		17.2
(-3)
P 		17
avr 30.7
(3) 		27.7
(1.3) 		20.2
(-3) 		20.6
(-2.8) 		11

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 25
1 2 3 4 5 6 range
A 16.8
(0.6)
M 		15.5
(0.1)
A 		7.8
(-3)
P 		18.6
(1.3)
P 		20.4
(2.1)
P 		22.7
(3)
P 		15
B 31.2
(2.6)
A 		16.8
(-1.6)
A 		12
(-3)
A 		18.2
(-1.2)
P 		32.5
(3)
P 		11.9
(-3)
P 		21
C 31.3
(3)
P 		16.5
(-1.4)
P 		11.1
(-3)
A 		12.9
(-2.5)
P 		23.1
(0.6)
P 		21.8
(0.2)
P 		20
avr 26.4
(3) 		16.3
(-0.8) 		10.3
(-3) 		16.6
(-0.7) 		25.3
(2.6) 		18.8
(0.2) 		16
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188681_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.7103
Sequence Type Exemplar sequence
Representative Public ID F43D9.3 NCBI
Target Description F43D9.3 /REP_DB=WormBase Gene ID /WP=CE00993 /TR=Q20364 /GB=CAA84704.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Sec1 family
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066916(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066916 NCBI Caenorhabditis elegans F43D9.3 (F43D9.3) mRNA, complete cds. 11/11 None
F43D9.3 ENSEMBL cdna:known chromosome:CEL140:III:10506920:10512894:1 gene:F43D9.3 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000024073 6/11 Cross Hyb Matching Probes None
GENEFINDER00000024075 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:10506915-10512536(+) 100.0 100.0
Public Domain and Genome References
Gene Title Sec1 family
Ensembl F43D9.3
Entrez Gene 185707 Entrez gene
SwissProt Q20364 EMBL-EBI
WormBase CE00993 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:20552_AT sec1 family protein at
ATH1-121501:265822_AT sec1 family protein at
CANINE:1599093_AT similar to vesicle transport-related protein isoform a cfa
CANINE_2:CFAAFFX.19701.1.S1_AT similar to vesicle transport-related protein isoform a cfa
CANINE_2:CFAAFFX.19725.1.S1_AT similar to vesicle transport-related protein isoform a cfa
CANINE_2:CFAAFFX.19725.1.S1_S_AT similar to vesicle transport-related protein isoform a cfa
DROSOPHILA_2:1625208_AT SLY-1 homologous dm
DROSOPHILA_2:1636044_AT SLY-1 homologous dm
DROSGENOME1:143849_AT SLY-1 homologous dm
CHICKEN:GGAAFFX.6231.1.S1_AT similar to vesicle transport-related protein isoform a; vesicle transport-related protein; chromosome 14 open reading frame 163 gga
CHICKEN:GGAAFFX.6231.1.S1_S_AT similar to vesicle transport-related protein isoform a; vesicle transport-related protein; chromosome 14 open reading frame 163 gga
CHICKEN:GGAAFFX.6231.2.S1_AT similar to vesicle transport-related protein isoform a; vesicle transport-related protein; chromosome 14 open reading frame 163 gga
HG-U133_PLUS_2:233229_AT sec1 family domain containing 1 hs
HG-U133B:233229_AT sec1 family domain containing 1 hs
HG-U133_PLUS_2:215548_S_AT sec1 family domain containing 1 hs
HG-U133A_2:215548_S_AT sec1 family domain containing 1 hs
HG-FOCUS:215548_S_AT sec1 family domain containing 1 hs
HG-U133A:215548_S_AT sec1 family domain containing 1 hs
HU35KSUBA:RC_AA150088_AT sec1 family domain containing 1 hs
HU35KSUBA:AA458770_AT sec1 family domain containing 1 hs
U133_X3P:HS.283564.0.S1_3P_AT sec1 family domain containing 1 hs
U133_X3P:HS.27023.1.S1_3P_S_AT sec1 family domain containing 1 hs
HG-U95AV2:33930_AT sec1 family domain containing 1 hs
HG-U95D:82808_AT sec1 family domain containing 1 hs
HG-U95D:82811_G_AT sec1 family domain containing 1 hs
U133_X3P:HS.293093.0.A1_3P_AT Sec1 family domain containing 1 hs
HG-U133_PLUS_2:243525_AT Sec1 family domain containing 1 hs
HG-U133B:243525_AT Sec1 family domain containing 1 hs
HG-U133_PLUS_2:241775_AT Sec1 family domain containing 1 hs
HG-U133B:241775_AT Sec1 family domain containing 1 hs
HG-U95C:62218_AT Sec1 family domain containing 1 hs
HG-U95E:67733_AT Sec1 family domain containing 1 hs
HG-U95E:70026_AT Sec1 family domain containing 1 hs
HG-U95E:71340_R_AT Sec1 family domain containing 1 hs
HG-U95D:85739_AT Sec1 family domain containing 1 hs
HG-U95E:90853_AT Sec1 family domain containing 1 hs
HU35KSUBB:RC_R10759_AT Sec1 family domain containing 1 hs
U133_X3P:HS.202536.0.A1_3P_AT Sec1 family domain containing 1 hs
MG-U74BV2:114345_AT sec1 family domain containing 1 mm
MG-U74CV2:134518_AT sec1 family domain containing 1 mm
MOE430A:1428006_AT sec1 family domain containing 1 mm
MOUSE430A_2:1428006_AT sec1 family domain containing 1 mm
MOUSE430_2:1428006_AT sec1 family domain containing 1 mm
MOE430A:1428335_A_AT sec1 family domain containing 1 mm
MOUSE430A_2:1428335_A_AT sec1 family domain containing 1 mm
MOUSE430_2:1428335_A_AT sec1 family domain containing 1 mm
MOE430B:1444845_AT sec1 family domain containing 1 mm
MOUSE430_2:1444845_AT sec1 family domain containing 1 mm
MU19KSUBC:TC40383_AT Sec1 family domain containing 1, mRNA (cDNA clone MGC:38021 IMAGE:5151118) mm
RG-U34A:D79221_AT sec1 family domain containing 1 rn
RAE230A:1368158_AT sec1 family domain containing 1 rn
RAT230_2:1368158_AT sec1 family domain containing 1 rn
RAE230B:1381579_AT Sec1 family domain containing 1 rn
RAT230_2:1381579_AT Sec1 family domain containing 1 rn
RG-U34A:RC_AI071399_AT Sec1 family domain containing 1 rn
YEAST_2:1779575_AT Hydrophilic protein involved in vesicle trafficking between the ER and Golgi; SM (Sec1/Munc-18) family protein that binds the tSNARE Sed5p and stimulates its assembly into a trans-SNARE membrane-protein complex Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
9306 protein secretion inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8565 protein transporter activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA84704 Hypothetical protein F43D9.3 [Caenorhabditis elegans] ref|NP_499317.1| F43D9.3 [Caenorhabditis elegans] 0.0
blast CAE71453 Hypothetical protein CBG18370 [Caenorhabditis briggsae] 0.0
blast NP_878281 suppressor of ypt1 [Danio rerio] emb|CAD58746.1| suppressor of ypt1 [Danio rerio] emb|CAD61086.1| novel vesicle-transport related protein [Danio rerio] gb|AAN87034.1| Sly1 [Danio rerio] 1.0E-160
Protein Domains
Database ID Description E-Value
Pfam IPR001619 EMBL-EBI Sec1-like protein 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:188681_AT
gtgcagaagctcaaatccatttcccaacttggatcccgagccgccaactctgctcacaca
gaagagcatcaaggtgctggaacaaaaacgataagcatgttcggaaagcttctaagtcat
agttcgaaatttgtaatggaaggagtcaagaatttggtgccaaaagagcacaatttgcca
cttacaaaaatgattgattcactgaatacgccaccatcatcaactggaatatcatcagct
gttggaattaatcaaatgattggaggatcatcacaaggacctgatattgatgatatttat
tgctttttcgatccaaaattgatgcatcagccgacgaaggaaaccatcctgcttgcccgt
caacaatctgcccaagacgtcattcttttcgttgttggaggtggaaactacgtggaatat
caaaatcttgtggattacggtaaacgaaaaaatctgatgcgagtcacctacggatgcacg
gagctcgtgaatcccgcacaattctgcgatcaggttagttgttgctctctctctctcccg
ttgactgacttatctggcga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTGCAGAAGCTCAAATCCATTTCCC 402 481 1540 Antisense
CGCCAACTCTGCTCACACAGAAGAG 675 257 1581 Antisense
AATACGCCACCATCATCAACTGGAA 341 173 1744 Antisense
GACGAAGGAAACCATCCTGCTTGCC 503 379 1872 Antisense
AACAATCTGCCCAAGACGTCATTCT 254 135 1901 Antisense
CGTCATTCTTTTCGTTGTTGGAGGT 88 245 1917 Antisense
TGATGCGAGTCACCTACGGATGCAC 474 565 1994 Antisense
GATGCACGGAGCTCGTGAATCCCGC 334 413 2012 Antisense
AATCCCGCACAATTCTGCGATCAGG 176 169 2029 Antisense
CGATCAGGTTAGTTGTTGCTCTCTC 182 249 2046 Antisense
TCCCGTTGACTGACTTATCTGGCGA 494 597 2075 Antisense
Sequence Source Affymetrix Proprietary Database