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[188652_at] peptidase

Description F39E9.4 /REP_DB=WormBase Gene ID /WP=CE10104 /TR=O17110 /GB=AAB70368.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=peptidase
Cluster 6grp_total > 99      4grp_total > 18      6grp_total_sub > Increase      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 100
1 2 3 4 range
A 24.2
(-3)
A 		67.9
(0)
A 		46.6
(-1.5)
A 		111.3
(3)
A 		87
B 40.9
(-0.8)
A 		38
(-1)
A 		11.3
(-3)
A 		92.7
(3)
A 		81
C 12.8
(-3)
A 		52
(0.7)
A 		28.9
(-1.5)
A 		75.6
(3)
A 		63
avr 26
(-3) 		52.6
(-0.6) 		28.9
(-2.7) 		93.2
(3) 		67

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 61
1 2 3 4 5 6 range
A 8
(-3)
A 		19.3
(-1.6)
A 		58.2
(3)
A 		37.6
(0.5)
A 		33.8
(0.1)
A 		30.6
(-0.3)
A 		50
B 15.6
(-1.4)
A 		32.3
(0.5)
A 		25.6
(-0.3)
A 		2.2
(-3)
A 		53.5
(3)
A 		53.9
(3)
A 		52
C 28.5
(-1.4)
A 		38.1
(-0.2)
A 		35.8
(-0.5)
A 		15.6
(-3)
A 		63.2
(3)
A 		59
(2.5)
A 		48
avr 17.4
(-3) 		29.9
(-0.7) 		39.9
(1.1) 		18.5
(-2.8) 		50.2
(3) 		47.8
(2.6) 		33
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 17
1 2 3 4 range
A 8.8
(-3)
A 		14.7
(1.7)
A 		12.2
(-0.3)
A 		16.3
(3)
A 		8
B 13
(0.6)
A 		9.4
(-0.6)
A 		2.6
(-3)
A 		19.8
(3)
A 		17
C 4.2
(-3)
A 		14.9
(3)
A 		10.1
(0.3)
A 		12.7
(1.8)
A 		11
avr 8.7
(-2.7) 		13
(0.5) 		8.3
(-3) 		16.3
(3) 		8

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 21
1 2 3 4 5 6 range
A 1.5
(-3)
A 		6.9
(-0.1)
A 		12.7
(3)
A 		9.5
(1.3)
A 		10.2
(1.7)
A 		7.5
(0.2)
A 		11
B 5.4
(-1.6)
A 		10.7
(-0.1)
A 		6.2
(-1.4)
A 		0.6
(-3)
A 		21.7
(3)
A 		20.1
(2.5)
A 		21
C 10.6
(-0.4)
A 		11.6
(-0.1)
A 		9.1
(-0.9)
A 		3.1
(-3)
A 		20.4
(3)
A 		19.7
(2.8)
A 		17
avr 5.8
(-2.4) 		9.7
(-0.6) 		9.3
(-0.7) 		4.4
(-3) 		17.4
(3) 		15.8
(2.3) 		13
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188652_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.5624
Sequence Type Exemplar sequence
Representative Public ID F39E9.4 NCBI
Target Description F39E9.4 /REP_DB=WormBase Gene ID /WP=CE10104 /TR=O17110 /GB=AAB70368.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=peptidase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_062096(10)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_062096 NCBI Caenorhabditis elegans F39E9.4 (peptidase) mRNA, complete cds. 10/11 None
GENEFINDER00000020878 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:3284871:3292074:1 9/11 None
F39E9.4 ENSEMBL cdna:known chromosome:CEL140:II:3282649:3287148:1 gene:F39E9.4 10/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000020862 5/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:3284656-3287127(+) 100.0 100.0
Public Domain and Genome References
Gene Title peptidase
Ensembl F39E9.4
Entrez Gene 173672 Entrez gene
WormBase CE37371 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4245 neprilysin activity inferred from electronic annotation QuickGO AmiGO
8237 metallopeptidase activity inferred from electronic annotation QuickGO AmiGO
8270 zinc ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_494497 F39E9.4 [Caenorhabditis elegans] 0.0
blast AAZ91348 Hypothetical protein F39E9.4 [Caenorhabditis elegans] 0.0
blast AAB70367 Serpentine receptor, class i protein 63 [Caenorhabditis elegans] ref|NP_494498.1| Serpentine Receptor, class I family member (sri-63) [Caenorhabditis elegans] 1.0E-174
blast AAB66080 Hypothetical protein F18A12.1 [Caenorhabditis elegans] ref|NP_494537.1| F18A12.1 [Caenorhabditis elegans] 1.0E-136
Protein Domains
Database ID Description E-Value
Pfam IPR008753 EMBL-EBI Peptidase M13 5.5E-6
Pfam IPR008753 EMBL-EBI Peptidase M13 1.8E-8
Pfam IPR000718 EMBL-EBI Peptidase M13, neprilysin 6.1E-98
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 2.2E-77
Pfam IPR008753 EMBL-EBI Peptidase M13 1.8E-8
Pfam IPR000718 EMBL-EBI Peptidase M13, neprilysin 2.9E-88
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000020878 10 570-592,599-621,636-658,686-708,756-778,798-820,830-852,990-1012,1017-1039,1046-1068
Sequence
Target Sequence 
>C. ELEGANS:188652_AT
cgaaattccagatgtgctcgttccgtttctcgacaagccgctcttcgacttcaaataccc
ccgctacgtggcaatggctggagttggccgggtgttggctcacgagattggccacgcgtt
tgatataaatggccggcaaactgacgagattggcaggacgcgggactggtggacacggga
ggatacggaggagtatgataggcgaagtgaatgctttgcggagcaatttacaaacttcaa
ggatcctagttttaaagggaagcaaaacggaaccgaagttctcgctgaaatcattgcgga
tgctcttggaatggaagcttcatggattgcgttcaagaagatcaacctgactgaggaaca
gggtctcatacagtttgaggatcacgattttggaaagctatactttcaggttgccgcttt
ggatttctgtgctccgagccggatagaagagagatattctgatcagctgagccacccgac
caacaaattccgcataaatggagcattttccaactcacgagccttcgccgacacgtacaa
atgtccggttggctcgaagat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CGAAATTCCAGATGTGCTCGTTCCG 535 251 1410 Antisense
CCCGCTACGTGGCAATGGCTGGAGT 572 259 1469 Antisense
CGAGATTGGCCACGCGTTTGATATA 232 251 1512 Antisense
GACGAGATTGGCAGGACGCGGGACT 670 373 1552 Antisense
AAATCATTGCGGATGCTCTTGGAAT 425 117 1697 Antisense
ATACTTTCAGGTTGCCGCTTTGGAT 53 25 1809 Antisense
ATTTCTGTGCTCCGAGCCGGATAGA 659 13 1832 Antisense
GATATTCTGATCAGCTGAGCCACCC 490 427 1862 Antisense
TGGAGCATTTTCCAACTCACGAGCC 468 549 1908 Antisense
GCCTTCGCCGACACGTACAAATGTC 36 281 1930 Antisense
ACAAATGTCCGGTTGGCTCGAAGAT 11 113 1946 Antisense
Sequence Source Affymetrix Proprietary Database