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[188632_at] tyrosinase

Description K08E3.1 /REP_DB=WormBase Gene ID /WP=CE18864 /TR=Q9XUS8 /GB=CAB04594.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=tyrosinase
Cluster 6grp_highest_10_10 > 09      6grp_high1_10_10 > 80      6grp_highest_nonorm > 55      6grp_total > 82      4grp_total > 57      6grp_cgc > 74      6grp_high1_sub > 02_03_04_05      6grp_cgc_sub > 02_03_04_05      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 4219
1 2 3 4 range
A 884.7
(-1.9)
P 		4321.9
(3)
P 		4335.6
(3)
P 		116.6
(-3)
A 		4219
B 894
(-1.9)
P 		3593.2
(2.1)
P 		4188.6
(3)
P 		129.1
(-3)
A 		4060
C 765.2
(-2)
P 		3639.8
(2.9)
P 		3715.3
(3)
P 		172.9
(-3)
A 		3542
avr 848
(-1.9) 		3851.6
(2.7) 		4079.8
(3) 		139.5
(-3) 		3940

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1212
1 2 3 4 5 6 range
A 1030.3
(-3)
P 		1868.1
(1.8)
P 		1462
(-0.5)
P 		1680.4
(0.7)
P 		2085.9
(3)
P 		1402.5
(-0.9)
P 		1056
B 946.9
(-3)
P 		1828
(2.3)
P 		1636.1
(1.1)
P 		1649.8
(1.2)
P 		1951.7
(3)
P 		954
(-3)
P 		1005
C 1113.8
(-2.1)
P 		1611.7
(0.3)
P 		2151
(3)
P 		1675.2
(0.6)
P 		2148.5
(3)
P 		939.3
(-3)
P 		1212
avr 1030.3
(-3) 		1769.3
(1.3) 		1749.7
(1.2) 		1668.5
(0.7) 		2062
(3) 		1098.6
(-2.6) 		1032
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1278
1 2 3 4 range
A 322.1
(-1.4)
P 		938.2
(2)
P 		1133.4
(3)
P 		17.1
(-3)
A 		1116
B 285.1
(-1.4)
P 		887.4
(2.5)
P 		970.6
(3)
P 		27.5
(-3)
A 		943
C 253.3
(-1.9)
P 		1046.5
(1.8)
P 		1294.9
(3)
P 		29.1
(-3)
A 		1266
avr 286.8
(-1.6) 		957.4
(2) 		1133
(3) 		24.6
(-3) 		1108

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 603
1 2 3 4 5 6 range
A 189.9
(-3)
P 		664.4
(3)
P 		318.4
(-1.4)
P 		426.2
(-0)
P 		629.4
(2.6)
P 		341.5
(-1.1)
P 		475
B 329.5
(-3)
P 		608.5
(0.6)
P 		397.3
(-2.1)
P 		437
(-1.6)
P 		793
(3)
P 		355.8
(-2.7)
P 		464
C 412.8
(-1.4)
P 		491.8
(-0.2)
P 		547.5
(0.7)
P 		336.9
(-2.6)
P 		695.2
(3)
P 		314.4
(-3)
P 		381
avr 310.7
(-3) 		588.2
(1.2) 		421.1
(-1.3) 		400
(-1.6) 		705.9
(3) 		337.2
(-2.6) 		395
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188632_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6013
Sequence Type Exemplar sequence
Representative Public ID K08E3.1 NCBI
Target Description K08E3.1 /REP_DB=WormBase Gene ID /WP=CE18864 /TR=Q9XUS8 /GB=CAB04594.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=tyrosinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_067435(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_067435 NCBI Caenorhabditis elegans K08E3.1 (tyrosinase) mRNA, complete cds. 11/11 None
SNAP00000031959 ENSEMBL cdna:SNAP chromosome:CEL140:III:13743743:13750784:1 11/11 None
GENEFINDER00000031977 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:13743743:13746591:1 11/11 None
K08E3.1.3 ENSEMBL cdna:known chromosome:CEL140:III:13743416:13746591:1 gene:K08E3.1 11/11 None
K08E3.1.1 ENSEMBL cdna:known chromosome:CEL140:III:13743736:13746803:1 gene:K08E3.1 11/11 None
K08E3.1.2 ENSEMBL cdna:known chromosome:CEL140:III:13743738:13746591:1 gene:K08E3.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:13743738-13746587(+) 100.0 100.0
Public Domain and Genome References
Gene Title tyrosinase
Gene Symbol tyr-2
Ensembl K08E3.1
Entrez Gene 176810 Entrez gene
SwissProt Q9XUS8 EMBL-EBI
WormBase CE18864 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8152 metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
16491 oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB04594 Hypothetical protein K08E3.1 [Caenorhabditis elegans] ref|NP_499836.1| K08E3.1 [Caenorhabditis elegans] 0.0
blast CAE71374 Hypothetical protein CBG18278 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002227 EMBL-EBI Tyrosinase 1.2E-5
Pfam IPR002227 EMBL-EBI Tyrosinase 2.6E-14
Pfam IPR003582 EMBL-EBI Metridin-like ShK toxin 1.3E-12
Pfam IPR003582 EMBL-EBI Metridin-like ShK toxin 4.3E-11
Pfam IPR002227 EMBL-EBI Tyrosinase 1.2E-5
Pfam IPR002227 EMBL-EBI Tyrosinase 2.6E-14
Pfam IPR003582 EMBL-EBI Metridin-like ShK toxin 1.3E-12
Pfam IPR003582 EMBL-EBI Metridin-like ShK toxin 4.3E-11
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000031977 2 4-23,129-151
Sequence
Target Sequence 
>C. ELEGANS:188632_AT
gacgcttgctacgcttcaagatgctggtggggaagatgtgtaaatgctaatttcgccgct
cgcatgaagggagcccgtacacacgctaactccaccttaatcgacttggaacttgccaag
gaagtctccgtgaatggaaccaaagtcgagcgtgtccccctagtcaaaagaatctccatc
aagatgactgctccattatttgtcgactgctacaaccgaatgccgtgctgcgattcatgg
gccaagaatggcgggtgtcaacgggaaccagaattcatgagtcagtattgccaggcctcg
tgtaacacctgcacaccatcctacaacacaactgatgcttgtatggatcgacatgtgaac
tgtgtcgcctggaaggcggacaaaatgtgcagcggaaagtcggcagactttatgtcagag
aattgtagaagcagctgcggaaagtgctctttaacgagagaatcgcaatgcttcaataat
ggaaagatcatcgtaatcccagtttccc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GACGCTTGCTACGCTTCAAGATGCT 233 381 1429 Antisense
TAAATGCTAATTTCGCCGCTCGCAT 546 641 1469 Antisense
GCATGAAGGGAGCCCGTACACACGC 335 309 1490 Antisense
GCTAACTCCACCTTAATCGACTTGG 77 303 1513 Antisense
TGGAACCAAAGTCGAGCGTGTCCCC 538 545 1563 Antisense
GTGTCCCCCTAGTCAAAAGAATCTC 443 483 1580 Antisense
GCTCCATTATTTGTCGACTGCTACA 167 299 1618 Antisense
ATGGCGGGTGTCAACGGGAACCAGA 208 49 1676 Antisense
GTCAGTATTGCCAGGCCTCGTGTAA 288 465 1709 Antisense
ACATGTGAACTGTGTCGCCTGGAAG 384 95 1779 Antisense
AAGATCATCGTAATCCCAGTTTCCC 565 155 1912 Antisense
Sequence Source Affymetrix Proprietary Database