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[188597_s_at]

Description T17E9.1 /REP_DB=WormBase Gene ID /WP=CE01405 /GEN=kin-18 /TR=SW:P46549 /GB=AAA19437.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 84      6grp_high1_10_10 > 57      4grp_highest_8_8 > 45      4grp_high_8_8 > 01      6grp_highest_nonorm > 81      6grp_total > 48      4grp_total > 23      6grp_highest_sub > Cu      6grp_cgc > 17      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 217
1 2 3 4 range
A 338.8
(2.8)
P 		130.2
(-3)
P 		147.7
(-2.5)
P 		347.5
(3)
P 		217
B 329.9
(3)
P 		150.4
(-3)
P 		201.5
(-1.3)
P 		298.1
(1.9)
P 		180
C 326
(3)
P 		177.1
(-3)
P 		198.8
(-2.1)
P 		266.2
(0.6)
P 		149
avr 331.6
(3) 		152.6
(-3) 		182.7
(-2) 		303.9
(2.1) 		179

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 200
1 2 3 4 5 6 range
A 274.6
(-0.2)
P 		272.1
(-0.3)
P 		182.1
(-3)
P 		230.5
(-1.5)
P 		237.5
(-1.3)
P 		382
(3)
P 		200
B 316.6
(2.4)
P 		255.1
(-0.2)
P 		186
(-3)
P 		224.9
(-1.4)
P 		234.5
(-1)
P 		332.2
(3)
P 		146
C 351.8
(3)
P 		211.4
(-3)
P 		253.1
(-1.2)
P 		260.7
(-0.9)
P 		211.8
(-3)
P 		325.4
(1.9)
P 		140
avr 314.3
(1.6) 		246.2
(-1.3) 		207.1
(-3) 		238.7
(-1.6) 		227.9
(-2.1) 		346.5
(3) 		139
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 95
1 2 3 4 range
A 123.4
(3)
P 		28.3
(-3)
P 		38.6
(-2.4)
P 		50.9
(-1.6)
P 		95
B 105.2
(3)
P 		37.2
(-3)
P 		46.7
(-2.2)
P 		63.5
(-0.7)
P 		68
C 107.9
(3)
P 		50.9
(-2.4)
P 		69.3
(-0.7)
P 		44.9
(-3)
P 		63
avr 112.2
(3) 		38.8
(-3) 		51.5
(-2) 		53.1
(-1.8) 		73

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 91
1 2 3 4 5 6 range
A 50.6
(-1.9)
P 		96.8
(3)
P 		39.7
(-3)
P 		58.5
(-1)
P 		71.7
(0.4)
P 		93
(2.6)
P 		57
B 110.2
(2)
P 		84.9
(0)
P 		45.2
(-3)
P 		59.6
(-1.9)
P 		95.3
(0.8)
P 		123.9
(3)
P 		79
C 130.4
(3)
P 		64.5
(-2.1)
P 		64.4
(-2.1)
P 		52.4
(-3)
P 		68.5
(-1.8)
P 		108.9
(1.3)
P 		78
avr 97.1
(1.8) 		82.1
(0.3) 		49.8
(-3) 		56.8
(-2.3) 		78.5
(-0.1) 		108.6
(3) 		59
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 188597_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6243
Sequence Type Exemplar sequence
Representative Public ID T17E9.1 NCBI
Target Description T17E9.1 /REP_DB=WormBase Gene ID /WP=CE01405 /GEN=kin-18 /TR=SW:P46549 /GB=AAA19437.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001027596(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001027596 NCBI Caenorhabditis elegans protein KINase family member (kin-18) (kin-18) mRNA, complete cds. 11/11 None
SNAP00000026956 ENSEMBL cdna:SNAP chromosome:CEL140:III:6118835:6123466:1 11/11 None
GENEFINDER00000026959 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:6118835:6123466:1 11/11 None
T17E9.1a ENSEMBL cdna:known chromosome:CEL140:III:6118567:6124006:1 gene:T17E9.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Splice Variants
Entrez Total Refseq Isoforms Total Detected By This Probeset Refseq Probesets
175862 2 1 NM_001027596 175743_at (11), 188597_s_at (11)
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:6118833-6123465(+) 100.0 100.0
Public Domain and Genome References
Ensembl T17E9.1
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast AAA19437 Protein kinase protein 18, isoform a [Caenorhabditis elegans] ref|NP_001022767.1| protein KINase family member (kin-18) [Caenorhabditis elegans] sp|P46549|SULU_CAEEL Serine/threonine-protein kinase SULU gb|AAA75370.1| serine-threonine kinase 0.0
blast AAM97951 Protein kinase protein 18, isoform b [Caenorhabditis elegans] ref|NP_741172.2| protein KINase family member (kin-18) [Caenorhabditis elegans] 0.0
blast CAE73617 Hypothetical protein CBG21107 [Caenorhabditis briggsae] 0.0
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-14
hanks 2.1.17 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; TWITCH 1.0E-64
hanks 1.9.1 AGC group; AGC Other; DM 3.0E-58
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.7E-69
Pfam IPR000719 EMBL-EBI Protein kinase 0.0089
Pfam IPR000719 EMBL-EBI Protein kinase 3.1E-59
Sequence
Target Sequence 
>C. ELEGANS:188597_S_AT
gtgaagactcagactcgccaatttaagctctaccttacacaaatggtgcaagtagttcca
aaagatgaacaaaaagagctcacgtctcgactaaaacaggatcaaatgcaaaaagtcgca
cttcttgcttcacaatacgaaagtcaaatcaaaaaaatggttcaggataagacagtgaag
ctcgagtcgtggcaagaagatgaacaacgggttcttagtgagaagttggagaaagaattg
gaagaattgattgcttatcagaagaagacgagagccacattagaagagcagattaaaaag
gaacgtacggcactcgaagaacgaattggcacacgacgtgcaatgcttgaacagaagatt
attgaagaacgcgaacaaatgggagaaatgcgtcgactaaagaaggagcaaatccgtgat
cgacacagtcaagaacgccatcgtctcgagaatcatttcgtacggacgggctcgacgagc
agaagttctggtgggatcgctcct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTGAAGACTCAGACTCGCCAATTTA 473 481 2419 Antisense
GACTCGCCAATTTAAGCTCTACCTT 417 373 2430 Antisense
AAAGAGCTCACGTCTCGACTAAAAC 98 123 2491 Antisense
CAAAAAGTCGCACTTCTTGCTTCAC 403 191 2527 Antisense
GACAGTGAAGCTCGAGTCGTGGCAA 472 369 2589 Antisense
GGAACGTACGGCACTCGAAGAACGA 493 527 2718 Antisense
GCACACGACGTGCAATGCTTGAACA 426 317 2747 Antisense
GAGCAAATCCGTGATCGACACAGTC 464 389 2824 Antisense
CAGTCAAGAACGCCATCGTCTCGAG 337 207 2844 Antisense
GAATCATTTCGTACGGACGGGCTCG 501 327 2868 Antisense
CAGAAGTTCTGGTGGGATCGCTCCT 18 205 2898 Antisense
Sequence Source Affymetrix Proprietary Database