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[188543_s_at] lipase

Description R11G11.14 /REP_DB=WormBase Gene ID /WP=CE12766 /TR=O16956 /GB=AAC69088.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=lipase
Cluster 6grp_total > 93      4grp_total > 01      6grp_total_sub > Hat      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 144
1 2 3 4 range
A 13.5
(-3)
A 		14.7
(-2.9)
A 		38.9
(-1.9)
A 		153.6
(3)
A 		140
B 24.6
(-1.6)
A 		20.9
(-2.1)
A 		14.9
(-3)
A 		56.3
(3)
A 		41
C 11.3
(-2.9)
A 		17.3
(-2.5)
A 		9.4
(-3)
A 		100.7
(3)
A 		91
avr 16.5
(-3) 		17.6
(-2.9) 		21.1
(-2.7) 		103.5
(3) 		87

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 188
1 2 3 4 5 6 range
A 130.6
(-1.1)
A 		126.4
(-1.3)
A 		205.6
(2.5)
A 		89.3
(-3)
A 		216.8
(3)
A 		130.4
(-1.1)
A 		128
B 119.6
(-2)
A 		94.9
(-3)
A 		157.9
(-0.5)
A 		102.9
(-2.7)
A 		249.1
(3)
A 		142.3
(-1.2)
A 		154
C 133.6
(-0.1)
A 		107.3
(-1.2)
A 		165.3
(1.1)
A 		83.7
(-2.1)
A 		211.9
(3)
M 		60.9
(-3)
A 		151
avr 127.9
(-1.4) 		109.5
(-2.2) 		176.3
(0.8) 		92
(-3) 		225.9
(3) 		111.2
(-2.1) 		134
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 19
1 2 3 4 range
A 4.9
(-2.5)
A 		3.2
(-3)
A 		10.2
(-0.8)
A 		22.5
(3)
A 		19
B 7.8
(0.1)
A 		5.1
(-1.8)
A 		3.4
(-3)
A 		12
(3)
A 		9
C 3.7
(-2.8)
A 		5
(-2.3)
A 		3.3
(-3)
A 		17
(3)
A 		14
avr 5.5
(-2.5) 		4.4
(-3) 		5.6
(-2.4) 		17.2
(3) 		13

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 84
1 2 3 4 5 6 range
A 24.1
(-2.8)
A 		45
(0.1)
A 		44.8
(0.1)
A 		22.6
(-3)
A 		65.4
(3)
A 		31.7
(-1.7)
A 		43
B 41.6
(-1.8)
A 		31.6
(-2.7)
A 		38.3
(-2.1)
A 		27.3
(-3)
A 		101.2
(3)
A 		53
(-0.9)
A 		74
C 49.5
(0.8)
A 		32.7
(-1.2)
A 		42.1
(-0.1)
A 		16.8
(-3)
A 		68.6
(3)
M 		20.4
(-2.6)
A 		52
avr 38.4
(-1.3) 		36.4
(-1.5) 		41.7
(-0.9) 		22.2
(-3) 		78.4
(3) 		35
(-1.6) 		56
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 188543_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14794
Sequence Type Exemplar sequence
Representative Public ID R11G11.14 NCBI
Target Description R11G11.14 /REP_DB=WormBase Gene ID /WP=CE12766 /TR=O16956 /GB=AAC69088.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=lipase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_070832(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_070832 NCBI Caenorhabditis elegans R11G11.14 (lipase) mRNA, complete cds. 11/11 None
SNAP00000021488 ENSEMBL cdna:SNAP chromosome:CEL140:V:521641:524042:-1 11/11 None
GENEFINDER00000021499 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:521551:524969:-1 11/11 None
R11G11.14 ENSEMBL cdna:known chromosome:CEL140:V:521531:524047:-1 gene:R11G11.14 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:521640-524042(-) 100.0 100.0
Public Domain and Genome References
Gene Title lipase
Ensembl R11G11.14
Entrez Gene 178572 Entrez gene
SwissProt O16956 EMBL-EBI
WormBase CE28762 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:250199_AT lipase family protein at
ATH1-121501:250219_AT lipase family protein at
CANINE_2:CFAAFFX.24089.1.S1_AT similar to lipase A precursor cfa
DROSOPHILA_2:1634515_AT dm
DROSGENOME1:147235_AT dm
CHICKEN:GGA.14426.1.S1_AT lipase A, lysosomal acid, cholesterol esterase (Wolman disease) gga
CHICKEN:GGA.9879.1.S1_AT lipase A, lysosomal acid, cholesterol esterase (Wolman disease) gga
CHICKEN:GGA.9879.1.S1_S_AT lipase A, lysosomal acid, cholesterol esterase (Wolman disease) gga
CHICKEN:GGAAFFX.11785.1.S1_AT lipase A, lysosomal acid, cholesterol esterase (Wolman disease) gga
CHICKEN:GGAAFFX.11785.1.S1_S_AT lipase A, lysosomal acid, cholesterol esterase (Wolman disease) gga
HG-U133_PLUS_2:236156_AT lipase A, lysosomal acid, cholesterol esterase (Wolman disease) hs
HG-U133B:236156_AT lipase A, lysosomal acid, cholesterol esterase (Wolman disease) hs
HU35KSUBC:RC_D80411_AT lipase A, lysosomal acid, cholesterol esterase (Wolman disease) hs
HUGENEFL:Z31690_S_AT lipase A, lysosomal acid, cholesterol esterase (Wolman disease) hs
HUGENEFL:U04285_S_AT lipase A, lysosomal acid, cholesterol esterase (Wolman disease) hs
HG-U133A:201847_AT lipase A, lysosomal acid, cholesterol esterase (Wolman disease) hs
HG-U133_PLUS_2:201847_AT lipase A, lysosomal acid, cholesterol esterase (Wolman disease) hs
HG-FOCUS:201847_AT lipase A, lysosomal acid, cholesterol esterase (Wolman disease) hs
HG-U133A_2:201847_AT lipase A, lysosomal acid, cholesterol esterase (Wolman disease) hs
U133_X3P:G4557720_3P_AT lipase A, lysosomal acid, cholesterol esterase (Wolman disease) hs
U133_X3P:HS.45172.0.A1_3P_AT lipase A, lysosomal acid, cholesterol esterase (Wolman disease) hs
HG-U95AV2:38745_AT lipase A, lysosomal acid, cholesterol esterase (Wolman disease) hs
HG-U95B:53607_AT lipase A, lysosomal acid, cholesterol esterase (Wolman disease) hs
MG-U74AV2:102123_AT lysosomal acid lipase 1 mm
MOE430A:1423140_AT lysosomal acid lipase 1 mm
MOUSE430A_2:1423140_AT lysosomal acid lipase 1 mm
MOUSE430_2:1423140_AT lysosomal acid lipase 1 mm
MOE430A:1450872_S_AT lysosomal acid lipase 1 mm
MOUSE430A_2:1450872_S_AT lysosomal acid lipase 1 mm
MOUSE430_2:1450872_S_AT lysosomal acid lipase 1 mm
MOE430A:1423141_AT lysosomal acid lipase 1 mm
MOUSE430A_2:1423141_AT lysosomal acid lipase 1 mm
MOUSE430_2:1423141_AT lysosomal acid lipase 1 mm
MU19KSUBB:TC29156_AT Lysosomal acid lipase 1 (Lip1), mRNA mm
MU19KSUBB:TC31169_AT Lysosomal acid lipase 1 (Lip1), mRNA mm
RG-U34A:S81497_S_AT lipase A, lysosomal acid rn
RG-U34A:S81497_I_AT lipase A, lysosomal acid rn
RG-U34A:RC_AA874784_S_AT lipase A, lysosomal acid rn
RAE230A:1368075_AT lipase A, lysosomal acid rn
RAT230_2:1368075_AT lipase A, lysosomal acid rn
RG-U34B:RC_AJ007475_AT Lipase A, lysosomal acid rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6629 lipid metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3824 catalytic activity inferred from electronic annotation QuickGO AmiGO
16789 carboxylic ester hydrolase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_503233 R11G11.14 [Caenorhabditis elegans] gb|AAC69088.2| Hypothetical protein R11G11.14 [Caenorhabditis elegans] 0.0
blast CAE65482 Hypothetical protein CBG10449 [Caenorhabditis briggsae] 0.0
blast CAE58265 Hypothetical protein CBG01370 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR006693 EMBL-EBI Ab-hydrolase associated lipase region 2.7E-44
Pfam IPR006693 EMBL-EBI Ab-hydrolase associated lipase region 2.7E-44
Sequence
Target Sequence 
>C. ELEGANS:188543_S_AT
tgagttcctgccaaacaactgggcgatgaagctcgccgccaaggacatttgcggcggcct
gaaaatcgaatcggatctctgtgacaatgtgtgcttcctgattgccggaccggaaagtga
tcagtggaactccacacgagttccggtctacgcatcccatgatccagctggtactgccac
acagaatattgtgcattggattcagatggttcggcacggaggtgtcccggcgtatgattg
ggggagtaaggagaataagaagaatgtgaattttcaggcaaatccaccagagtacgactt
taccgctatcaagggaactcaaatttatctgtactggagtgatgcagattggctagctga
taagactgatatcaccaattacttgctgactcgcttgaatcctgctataattgcgcagaa
caactacttcactgactacaatcatttcgattttgtcttcgggctccgagctccaaatga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGAGTTCCTGCCAAACAACTGGGCG 304 567 699 Antisense
AACTGGGCGATGAAGCTCGCCGCCA 428 143 715 Antisense
GCGGCGGCCTGAAAATCGAATCGGA 496 291 749 Antisense
GATCTCTGTGACAATGTGTGCTTCC 378 419 772 Antisense
GAACTCCACACGAGTTCCGGTCTAC 340 335 825 Antisense
CATCCCATGATCCAGCTGGTACTGC 98 211 851 Antisense
GATTCAGATGGTTCGGCACGGAGGT 122 431 897 Antisense
GGCAAATCCACCAGAGTACGACTTT 434 535 975 Antisense
TTACTTGCTGACTCGCTTGAATCCT 419 683 1077 Antisense
CATTTCGATTTTGTCTTCGGGCTCC 597 193 1141 Antisense
TCTTCGGGCTCCGAGCTCCAAATGA 552 617 1154 Antisense
Sequence Source Affymetrix Proprietary Database