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[188525_at]

Description F42G9.2 /REP_DB=WormBase Gene ID /WP=CE01301 /GEN=cyp-6 /TR=SW:P52014 /GB=AAA91355.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 28      6grp_high1_10_10 > 71      4grp_highest_8_8 > 02      4grp_high_8_8 > 46      6grp_highest_nonorm > 45      6grp_total > 70      4grp_total > 49      6grp_highest_sub > 04      6grp_cgc > 85      6grp_high1_sub > 04      6grp_cgc_sub > 04      6grp_total_sub > Hat      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1948
1 2 3 4 range
A 378.3
(-3)
P 		2110.6
(3)
P 		1735.2
(1.7)
P 		408.4
(-2.9)
P 		1732
B 289.1
(-3)
P 		1963.3
(2.2)
P 		2236.7
(3)
P 		382.8
(-2.7)
P 		1948
C 418
(-2.8)
P 		1959.1
(3)
P 		1957.5
(3)
P 		365.2
(-3)
P 		1594
avr 361.8
(-3) 		2011
(3) 		1976.5
(2.9) 		385.5
(-2.9) 		1649

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 3220
1 2 3 4 5 6 range
A 1799.1
(-1.5)
P 		1333.5
(-2.4)
P 		2588.4
(0.1)
P 		4123
(3)
P 		1885.8
(-1.3)
P 		1001.5
(-3)
P 		3122
B 1896.3
(-0.8)
P 		1194.2
(-2.3)
P 		2864.1
(1.4)
P 		3574.7
(3)
P 		2552.4
(0.7)
P 		903.5
(-3)
P 		2671
C 1960.5
(-0.7)
P 		1107.9
(-2.8)
P 		2338.7
(0.2)
P 		3529.4
(3)
P 		2210
(-0.1)
P 		1004.4
(-3)
P 		2525
avr 1885.3
(-1) 		1211.9
(-2.5) 		2597.1
(0.5) 		3742.4
(3) 		2216.1
(-0.3) 		969.8
(-3) 		2773
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 622
1 2 3 4 range
A 137.7
(-1.8)
P 		458.1
(3)
P 		453.6
(2.9)
P 		59.8
(-3)
P 		398
B 92.2
(-2.9)
P 		484.9
(2.5)
P 		518.3
(3)
P 		81.6
(-3)
P 		437
C 138.4
(-2.3)
P 		563.2
(1.8)
P 		682.2
(3)
P 		61.6
(-3)
P 		621
avr 122.8
(-2.3) 		502.1
(2.4) 		551.4
(3) 		67.7
(-3) 		484

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 802
1 2 3 4 5 6 range
A 331.6
(-2.3)
P 		474.3
(-1.3)
P 		563.7
(-0.6)
P 		1045.7
(3)
P 		569
(-0.6)
P 		243.8
(-3)
P 		802
B 659.8
(-0.2)
P 		397.5
(-2.5)
P 		695.5
(0.1)
P 		946.8
(2.2)
P 		1037
(3)
P 		336.9
(-3)
P 		700
C 726.7
(3)
P 		338
(-3)
P 		595.2
(1)
P 		709.8
(2.7)
P 		715.1
(2.8)
P 		336.2
(-3)
P 		391
avr 572.7
(-0.3) 		403.3
(-2) 		618.1
(0.2) 		900.8
(3) 		773.7
(1.7) 		305.6
(-3) 		595
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188525_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8252
Sequence Type Exemplar sequence
Representative Public ID F42G9.2 NCBI
Target Description F42G9.2 /REP_DB=WormBase Gene ID /WP=CE01301 /GEN=cyp-6 /TR=SW:P52014 /GB=AAA91355.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064856(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_064856 NCBI Caenorhabditis elegans CYclophyliN family member (cyn-6) (cyn-6) mRNA, complete cds. 11/11 None
SNAP00000038495 ENSEMBL cdna:SNAP chromosome:CEL140:III:773409:774060:1 11/11 None
GENEFINDER00000038510 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:773409:774060:1 11/11 None
F42G9.2 ENSEMBL cdna:known chromosome:CEL140:III:773398:774155:1 gene:F42G9.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:773408-774060(+) 100.0 100.0
Public Domain and Genome References
Gene Title
Gene Symbol cyn-6
Ensembl F42G9.2
Entrez Gene 175231 Entrez gene
SwissProt P52014 EMBL-EBI
WormBase CE01301 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:20350_S_AT peptidyl-prolyl cis-trans isomerase / cyclophilin (CYP5) / rotamase at
ATH1-121501:266804_AT peptidyl-prolyl cis-trans isomerase / cyclophilin (CYP5) / rotamase at
CANINE:1584030_AT similar to Peptidyl-prolyl cis-trans isomerase C (PPIase) (Rotamase) (Cyclophilin C) cfa
CANINE_2:CFA.6446.1.A1_AT similar to Peptidyl-prolyl cis-trans isomerase C (PPIase) (Rotamase) (Cyclophilin C) cfa
CANINE_2:CFAAFFX.1740.1.S1_AT similar to Peptidyl-prolyl cis-trans isomerase C (PPIase) (Rotamase) (Cyclophilin C) cfa
HG-U133A:204518_S_AT peptidylprolyl isomerase C (cyclophilin C) hs
HG-U133_PLUS_2:204518_S_AT peptidylprolyl isomerase C (cyclophilin C) hs
HG-U133A_2:204518_S_AT peptidylprolyl isomerase C (cyclophilin C) hs
HU35KSUBA:S71018_AT peptidylprolyl isomerase C (cyclophilin C) hs
HUGENEFL:S71018_AT peptidylprolyl isomerase C (cyclophilin C) hs
HU35KSUBC:RC_N69331_AT peptidylprolyl isomerase C (cyclophilin C) hs
U133_X3P:G4505990_3P_A_AT peptidylprolyl isomerase C (cyclophilin C) hs
U133_X3P:HS.110364.0.S2_3P_AT peptidylprolyl isomerase C (cyclophilin C) hs
HG-U133A_2:204517_AT peptidylprolyl isomerase C (cyclophilin C) hs
HG-FOCUS:204517_AT peptidylprolyl isomerase C (cyclophilin C) hs
HG-U133_PLUS_2:204517_AT peptidylprolyl isomerase C (cyclophilin C) hs
HG-U133A:204517_AT peptidylprolyl isomerase C (cyclophilin C) hs
HG-U95AV2:37422_AT peptidylprolyl isomerase C (cyclophilin C) hs
MU11KSUBA:M74227_S_AT peptidylprolyl isomerase C mm
MG-U74AV2:100089_AT peptidylprolyl isomerase C mm
MOE430A:1416498_AT peptidylprolyl isomerase C mm
MOUSE430A_2:1416498_AT peptidylprolyl isomerase C mm
MOUSE430_2:1416498_AT peptidylprolyl isomerase C mm
MU19KSUBA:TC23975_I_AT Peptidylprolyl isomerase C, mRNA (cDNA clone MGC:31015 IMAGE:5026674) mm
MU19KSUBA:TC23976_AT Peptidylprolyl isomerase C, mRNA (cDNA clone MGC:31015 IMAGE:5026674) mm
RAE230A:1375267_AT peptidylprolyl isomerase C rn
RAT230_2:1375267_AT peptidylprolyl isomerase C rn
YEAST_2:1770201_AT Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; has a potential role in the secretory pathway Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6457 protein folding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA91355 Cyclophylin protein 6 [Caenorhabditis elegans] ref|NP_497257.1| CYclophyliN family member (cyn-6) [Caenorhabditis elegans] sp|P52014|CYP6_CAEEL Peptidyl-prolyl cis-trans isomerase 6 precursor (PPIase) (Rotamase) (Cyclophilin-6) gb|AAC47124.1| cyclophilin 1.0E-94
blast CAE69202 Hypothetical protein CBG15242 [Caenorhabditis briggsae] 1.0E-88
blast CAE72552 Hypothetical protein CBG19736 [Caenorhabditis briggsae] 6.0E-71
Protein Domains
Database ID Description E-Value
Pfam IPR002130 EMBL-EBI Peptidyl-prolyl cis-trans isomerase, cyclophilin type 8.9E-106
Sequence
Target Sequence 
>C. ELEGANS:188525_AT
ttctcgccattctggctttgtcagccgaggcacgtggaccacgtgtcactgacaaggtct
tctttgacatggagatcggaggaagacctgttgggaaaatcgtcatcggacttttcggag
aggtcgtgccgaagacagtgaagaatttcgttgagttggcacagagagctgagggagaag
gatacgttggtagcaagttccaccgtgtcatcgaaaacttcatgattcaaggtggagact
tcacacgtggcgacggaaccggtggacgatcgatctacggcgagcgctttgaagatgaga
acttcaagcttcaacactacggaccaggatggttgtcaatggccaacgctggagaagata
ccaatggatctcaatttttcatcactaccgccaaaacctcatggctcgatggaaagcatg
tggtgttcggtaagatcctggaaggaatggacgtagttcgtgagatcgaggctacaccaa
aaggagctggagatcggccaattgaggatgttgtcatcgccaacgctggacatattc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTCTCGCCATTCTGGCTTTGTCAGC 34 693 38 Antisense
TTTGTCAGCCGAGGCACGTGGACCA 561 667 54 Antisense
CGTGGACCACGTGTCACTGACAAGG 291 245 70 Antisense
ACGTTGGTAGCAAGTTCCACCGTGT 449 91 221 Antisense
TCCACCGTGTCATCGAAAACTTCAT 361 587 236 Antisense
AGACTTCACACGTGGCGACGGAACC 506 69 273 Antisense
GACGGAACCGGTGGACGATCGATCT 264 377 289 Antisense
ATCGATCTACGGCGAGCGCTTTGAA 421 35 306 Antisense
AAGCTTCAACACTACGGACCAGGAT 596 149 343 Antisense
CTACCGCCAAAACCTCATGGCTCGA 418 225 422 Antisense
GTCATCGCCAACGCTGGACATATTC 428 467 550 Antisense
Sequence Source Affymetrix Proprietary Database