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[188520_at] protease

Description C11D2.2 /REP_DB=WormBase Gene ID /WP=CE16843 /TR=O45072 /GB=AAC02571.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=protease
Cluster 6grp_total > 87      4grp_total > 02      6grp_total_sub > Increase      6grp_rule_based > S6      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1614
1 2 3 4 range
A 73.6
(-2.8)
A 		44.3
(-2.9)
A 		29.7
(-3)
A 		1170.4
(3)
P 		1141
B 45.8
(-2.9)
M 		22.4
(-3)
A 		45.3
(-2.9)
A 		1636.1
(3)
P 		1614
C 65.4
(-2.9)
M 		47
(-3)
A 		39
(-3)
A 		1350.6
(3)
P 		1312
avr 61.6
(-2.9) 		37.9
(-3) 		38
(-3) 		1385.7
(3) 		1348

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2098
1 2 3 4 5 6 range
A 63.2
(-2.9)
A 		44.9
(-3)
A 		58.3
(-2.9)
A 		277.5
(-2)
P 		998.5
(1.3)
P 		1384.4
(3)
P 		1340
B 73.4
(-2.9)
A 		52
(-3)
A 		88.4
(-2.9)
A 		350.7
(-1.9)
P 		1056.1
(0.6)
P 		1714.1
(3)
P 		1662
C 63.1
(-2.9)
M 		23
(-3)
A 		60.3
(-2.9)
M 		409.8
(-1.9)
P 		812.4
(-0.7)
P 		2120.7
(3)
P 		2098
avr 66.6
(-2.9) 		40
(-3) 		69
(-2.9) 		346
(-1.9) 		955.7
(0.2) 		1739.7
(3) 		1700
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 343
1 2 3 4 range
A 26.8
(-2.3)
A 		9.6
(-2.9)
A 		7.8
(-3)
A 		171.3
(3)
P 		164
B 14.6
(-2.8)
M 		5.5
(-3)
A 		10.5
(-2.9)
A 		348.7
(3)
P 		343
C 21.7
(-2.8)
M 		13.5
(-3)
A 		13.6
(-3)
A 		227.7
(3)
P 		214
avr 21
(-2.7) 		9.5
(-3) 		10.6
(-3) 		249.2
(3) 		240

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 703
1 2 3 4 5 6 range
A 11.7
(-3)
A 		16
(-2.9)
A 		12.7
(-3)
A 		70.4
(-1.9)
P 		301.3
(2.3)
P 		337.1
(3)
P 		325
B 25.5
(-2.9)
A 		17.3
(-3)
A 		21.5
(-3)
A 		92.9
(-2.3)
P 		429.1
(1)
P 		639.2
(3)
P 		622
C 23.4
(-2.9)
M 		7
(-3)
A 		15.4
(-2.9)
M 		82.4
(-2.4)
P 		262.9
(-0.8)
P 		709.9
(3)
P 		703
avr 20.2
(-2.9) 		13.4
(-3) 		16.5
(-3) 		81.9
(-2.3) 		331.1
(0.5) 		562.1
(3) 		549
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188520_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.10794
Sequence Type Exemplar sequence
Representative Public ID C11D2.2 NCBI
Target Description C11D2.2 /REP_DB=WormBase Gene ID /WP=CE16843 /TR=O45072 /GB=AAC02571.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=protease
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_068527(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_068527 NCBI Caenorhabditis elegans C11D2.2 (protease) mRNA, complete cds. 11/11 None
SNAP00000030433 ENSEMBL cdna:SNAP chromosome:CEL140:IV:6185873:6189189:1 11/11 None
GENEFINDER00000030435 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:6185873:6189189:1 11/11 None
C11D2.2 ENSEMBL cdna:known chromosome:CEL140:IV:6185136:6189189:1 gene:C11D2.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:6185141-6189195(+) 100.0 100.0
Public Domain and Genome References
Gene Title protease
Ensembl C11D2.2
Entrez Gene 182511 Entrez gene
SwissProt O45072 EMBL-EBI
WormBase CE16843 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4190 aspartic-type endopeptidase activity inferred from electronic annotation QuickGO AmiGO
4194 pepsin A activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC02571 Hypothetical protein C11D2.2 [Caenorhabditis elegans] ref|NP_500928.1| C11D2.2 [Caenorhabditis elegans] 0.0
blast CAE61591 Hypothetical protein CBG05505 [Caenorhabditis briggsae] 1.0E-180
blast CAE61591 Hypothetical protein CBG05505 [Caenorhabditis briggsae] 1.0E-174
blast CAE61591 Hypothetical protein CBG05505 [Caenorhabditis briggsae] 1.0E-168
blast AAO25990 Aspartyl protease protein 2, isoform b [Caenorhabditis elegans] ref|NP_872129.1| ASpartyl Protease family member (asp-2) [Caenorhabditis elegans] 2.0E-84
blast CAE66088 Hypothetical protein CBG11305 [Caenorhabditis briggsae] 1.0E-83
Protein Domains
Database ID Description E-Value
Pfam IPR001461 EMBL-EBI Peptidase A1, pepsin 2.9E-84
Pfam IPR001461 EMBL-EBI Peptidase A1, pepsin 2.9E-84
Pfam IPR001461 EMBL-EBI Peptidase A1, pepsin 1.0E-10
Pfam IPR001461 EMBL-EBI Peptidase A1, pepsin 2.5E-69
Sequence
Target Sequence 
>C. ELEGANS:188520_AT
tttagcagtccatagtgtacctcctccatttgtgaatgcagttgagcagggtcttgttga
tgaaccaatattcacagtttatcttgaacatcatggaatcaaaaaagaggcaagcggtgg
atatttcacttatggtggagaagatcctgatcattgcggggagattattacatggattcc
gttgacaaaagcagcatattggcagtttagaatgcaaggaattggaatcgacaacgtcaa
tgaacacaaaaatggttgggaagtcatctcagataccggaacttctttcattggaggccc
aggaaaagttattcaggatattgcaaataaatatggagcaacttatgatgagtatagtga
ctcctacgtgataccatgctctgaaattaaaaatcttcgttcattgaaaatgaaaatcaa
cgatctcacgtttgaaattgatccaatcaatttggtggctcatcctgactccagcgaatg
tgatttgactcttttcgatatgtatggtggaggtttcggaccatcatggatccttggtga
tccatttattcgtcaattct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTTAGCAGTCCATAGTGTACCTCCT 279 673 579 Antisense
GCAGTTGAGCAGGGTCTTGTTGATG 553 311 616 Antisense
GGCAAGCGGTGGATATTTCACTTAT 186 531 687 Antisense
GAAGATCCTGATCATTGCGGGGAGA 150 339 718 Antisense
AAGTCATCTCAGATACCGGAACTTC 649 155 839 Antisense
CGGAACTTCTTTCATTGGAGGCCCA 584 241 855 Antisense
TCCTACGTGATACCATGCTCTGAAA 671 589 940 Antisense
ATCAATTTGGTGGCTCATCCTGACT 645 25 1024 Antisense
CTCATCCTGACTCCAGCGAATGTGA 625 227 1037 Antisense
GGACCATCATGGATCCTTGGTGATC 243 523 1096 Antisense
GGTGATCCATTTATTCGTCAATTCT 279 501 1114 Antisense
Sequence Source Affymetrix Proprietary Database