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[188513_at]

Description M142.1 /REP_DB=WormBase Gene ID /WP=CE06203 /GEN=unc-119 /TR=SW:Q10658 /GB=CAA97807.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 51      6grp_high1_10_10 > 03      4grp_highest_8_8 > 54      4grp_high_8_8 > 10      6grp_highest_nonorm > 50      6grp_total > 25      4grp_total > 22      6grp_highest_sub > De      6grp_cgc > 24      6grp_high1_sub > De      6grp_cgc_sub > Cu      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 306
1 2 3 4 range
A 631
(3)
P 		422.8
(-1.1)
P 		325.5
(-3)
P 		624.7
(2.9)
P 		306
B 600.9
(3)
P 		342.7
(-3)
P 		431.4
(-0.9)
P 		539.2
(1.6)
P 		258
C 600.2
(2.1)
P 		562.5
(1.1)
P 		409.7
(-3)
P 		631.9
(3)
P 		222
avr 610.7
(3) 		442.7
(-1.5) 		388.9
(-3) 		598.6
(2.7) 		222

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 591
1 2 3 4 5 6 range
A 852.3
(3)
P 		616.5
(0.2)
P 		384.1
(-2.6)
P 		353
(-3)
P 		358.2
(-2.9)
P 		390.6
(-2.5)
P 		499
B 577.4
(3)
P 		537.4
(2.2)
P 		556.9
(2.6)
P 		326.6
(-1.9)
P 		270.5
(-3)
P 		320.6
(-2)
P 		307
C 721.8
(3)
P 		646.9
(2)
P 		512.3
(0.3)
P 		426
(-0.9)
P 		261.8
(-3)
P 		416
(-1)
P 		460
avr 717.2
(3) 		600.3
(1.3) 		484.4
(-0.3) 		368.5
(-2) 		296.8
(-3) 		375.7
(-1.9) 		420
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 145
1 2 3 4 range
A 229.8
(3)
P 		91.8
(-2.7)
P 		85.1
(-3)
P 		91.4
(-2.7)
P 		145
B 191.6
(3)
P 		84.7
(-3)
P 		100
(-2.1)
P 		114.9
(-1.3)
P 		107
C 198.7
(3)
P 		161.7
(0.6)
P 		142.8
(-0.6)
P 		106.5
(-3)
P 		92
avr 206.7
(3) 		112.7
(-2.5) 		109.3
(-2.7) 		104.3
(-3) 		102

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 184
1 2 3 4 5 6 range
A 157.1
(0.2)
P 		219.3
(3)
P 		83.6
(-3)
P 		89.5
(-2.7)
P 		108.1
(-1.9)
P 		95.1
(-2.5)
P 		136
B 200.9
(3)
P 		178.9
(1.8)
P 		135.2
(-0.4)
P 		86.5
(-3)
P 		109.9
(-1.8)
P 		119.6
(-1.3)
P 		114
C 267.5
(3)
P 		197.4
(0.7)
P 		130.4
(-1.5)
P 		85.7
(-3)
P 		84.7
(-3)
P 		139.3
(-1.2)
P 		183
avr 208.5
(3) 		198.5
(2.5) 		116.4
(-1.6) 		87.2
(-3) 		100.9
(-2.3) 		118
(-1.5) 		121
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188513_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6818
Sequence Type Exemplar sequence
Representative Public ID M142.1 NCBI
Target Description M142.1 /REP_DB=WormBase Gene ID /WP=CE06203 /GEN=unc-119 /TR=SW:Q10658 /GB=CAA97807.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066998(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066998 NCBI Caenorhabditis elegans UNCoordinated family member (unc-119) (unc-119) mRNA, complete cds. 11/11 None
SNAP00000000571 ENSEMBL cdna:SNAP chromosome:CEL140:III:10907475:10916434:1 11/11 None
GENEFINDER00000000578 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:10907475:10908631:1 11/11 None
M142.1 ENSEMBL cdna:known chromosome:CEL140:III:10906347:10908737:1 gene:M142.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:10906342-10908627(+) 100.0 100.0
Public Domain and Genome References
Gene Title
Gene Symbol unc-119
Ensembl M142.1
Entrez Gene 176519 Entrez gene
SwissProt Q10658 EMBL-EBI
WormBase CE06203 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.16288.1.S1_AT similar to Unc119c cfa
DROSOPHILA_2:1628148_AT dm
DROSGENOME1:155038_AT dm
CHICKEN:GGA.20064.1.S1_S_AT similar to expressed sequence AA407659 gga
MU11KSUBA:AA407659_RC_S_AT expressed sequence AA407659 mm
MG-U74AV2:104434_AT expressed sequence AA407659 mm
MOE430A:1460688_S_AT expressed sequence AA407659 mm
MOUSE430A_2:1460688_S_AT expressed sequence AA407659 mm
MOUSE430_2:1460688_S_AT expressed sequence AA407659 mm
MOE430A:1460733_AT expressed sequence AA407659 mm
MOUSE430A_2:1460733_AT expressed sequence AA407659 mm
MOUSE430_2:1460733_AT expressed sequence AA407659 mm
MOUSE430_2:1437961_X_AT Expressed sequence AA407659, mRNA (cDNA clone IMAGE:3588380) mm
MOE430B:1437961_X_AT Expressed sequence AA407659, mRNA (cDNA clone IMAGE:3588380) mm
MU19KSUBA:TC16087_AT Expressed sequence AA407659, mRNA (cDNA clone IMAGE:3588380) mm
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
30424 axon inferred from direct assay QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA97806 Hypothetical protein M142.2 [Caenorhabditis elegans] ref|NP_499400.2| M142.2 [Caenorhabditis elegans] 0.0
blast CAE71373 Hypothetical protein CBG18277 [Caenorhabditis briggsae] 1.0E-171
blast AAT12434 UNC-119 [Cloning vector pWormgate2] emb|CAA97807.1| Hypothetical protein M142.1 [Caenorhabditis elegans] ref|NP_499399.1| UNCoordinated family member (unc-119) [Caenorhabditis elegans] sp|Q10658|UN119_CAEEL Unc-119 protein gb|AAC46919.1| unc-119 gene product 1.0E-125
blast AAT12434 UNC-119 [Cloning vector pWormgate2] emb|CAA97807.1| Hypothetical protein M142.1 [Caenorhabditis elegans] ref|NP_499399.1| UNCoordinated family member (unc-119) [Caenorhabditis elegans] sp|Q10658|UN119_CAEEL Unc-119 protein gb|AAC46919.1| unc-119 gene product 1.0E-114
blast Q17297 Unc-119 protein emb|CAE71384.1| Hypothetical protein CBG18291 [Caenorhabditis briggsae] 1.0E-111
blast AAB41283 UNC-119 1.0E-110
blast CAE71372 Hypothetical protein CBG18276 [Caenorhabditis briggsae] 1.0E-103
Protein Domains
Database ID Description E-Value
Pfam IPR002035 EMBL-EBI von Willebrand factor, type A 5.3E-58
Pfam IPR001507 EMBL-EBI Endoglin/CD105 antigen 7.4E-54
Pfam IPR008015 EMBL-EBI GMP-PDE, delta subunit 5.8E-78
Pfam IPR008015 EMBL-EBI GMP-PDE, delta subunit 1.4E-103
Pfam IPR008015 EMBL-EBI GMP-PDE, delta subunit 1.4E-103
Sequence
Target Sequence 
>C. ELEGANS:188513_AT
cgaacaggctataaccaccgaggcggagcttctcgcgaaaaatcaaattacaccaaatga
tgtgctagctcttccaggaatcactcaaggattcctatgctccccatcggcaaacgtcta
taacattgagttcaccaaattccaaatccgtgacctcgacacggaacacgtgctcttcga
aattgcaaaaccggaaaatgagacggaagagaatctgcaggcgcaagccgaatcggcaag
atatgtccgatatcgatttgcgccgaattttctgaaattaaagacggtcggcgcgacggt
cgagttcaaggtcggcgat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CGAACAGGCTATAACCACCGAGGCG 411 253 96 Antisense
GAGGCGGAGCTTCTCGCGAAAAATC 375 403 115 Antisense
AATGATGTGCTAGCTCTTCCAGGAA 571 163 151 Antisense
TCACTCAAGGATTCCTATGCTCCCC 301 627 176 Antisense
TCCCCATCGGCAAACGTCTATAACA 646 595 196 Antisense
CAAATTCCAAATCCGTGACCTCGAC 123 193 231 Antisense
GACCTCGACACGGAACACGTGCTCT 442 381 247 Antisense
GAATCTGCAGGCGCAAGCCGAATCG 125 329 306 Antisense
ATGTCCGATATCGATTTGCGCCGAA 48 49 338 Antisense
TAAAGACGGTCGGCGCGACGGTCGA 468 641 374 Antisense
GACGGTCGAGTTCAAGGTCGGCGAT 279 281 390 Antisense
Sequence Source Affymetrix Proprietary Database