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[188496_s_at] permease

Description T07G12.5 /REP_DB=WormBase Gene ID /WP=CE13395 /TR=O18057 /GB=CAB05270.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=permease
Cluster 6grp_total > 95      4grp_total > 10      6grp_total_sub > Increase      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 129
1 2 3 4 range
A 13.6
(-3)
A 		36.7
(3)
A 		28.5
(0.9)
A 		22.8
(-0.6)
A 		23
B 9
(-2.9)
A 		6.9
(-3)
A 		6.7
(-3)
A 		101.9
(3)
A 		95
C 10.1
(-2.6)
A 		11.8
(-2.6)
A 		2.5
(-3)
A 		131.1
(3)
A 		129
avr 10.9
(-3) 		18.5
(-2.4) 		12.6
(-2.9) 		85.3
(3) 		74

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 157
1 2 3 4 5 6 range
A 11.5
(-2.5)
A 		69.6
(0.7)
A 		3.5
(-3)
A 		69.8
(0.7)
A 		102.5
(2.6)
A 		109.9
(3)
A 		106
B 4.3
(-3)
A 		56
(-1)
A 		4.4
(-3)
A 		60.7
(-0.8)
A 		133.4
(2)
M 		160.1
(3)
P 		156
C 8
(-3)
A 		35.6
(-1.9)
A 		57.2
(-1)
A 		39.6
(-1.7)
A 		152.3
(3)
A 		104.5
(1)
P 		144
avr 7.9
(-3) 		53.7
(-0.7) 		21.7
(-2.3) 		56.7
(-0.6) 		129.4
(3) 		124.8
(2.8) 		122
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 21
1 2 3 4 range
A 5
(-0.8)
A 		8
(3)
A 		7.4
(2.2)
A 		3.3
(-3)
A 		5
B 2.9
(-2.6)
A 		1.7
(-3)
A 		1.6
(-3)
A 		21.7
(3)
A 		20
C 3.4
(-2.3)
A 		3.4
(-2.3)
A 		0.9
(-3)
A 		22.1
(3)
A 		21
avr 3.8
(-2.8) 		4.4
(-2.5) 		3.3
(-3) 		15.7
(3) 		12

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 59
1 2 3 4 5 6 range
A 2.1
(-2.7)
A 		24.7
(1.8)
A 		0.8
(-3)
A 		17.7
(0.4)
A 		30.9
(3)
A 		26.7
(2.2)
A 		30
B 1.5
(-3)
A 		18.6
(-1.2)
A 		1.1
(-3)
A 		16.1
(-1.5)
A 		54.2
(2.4)
M 		59.7
(3)
P 		59
C 3
(-3)
A 		10.9
(-2)
A 		14.6
(-1.5)
A 		8
(-2.4)
A 		49.3
(3)
A 		35
(1.1)
P 		46
avr 2.2
(-3) 		18.1
(-0.8) 		5.5
(-2.5) 		13.9
(-1.4) 		44.8
(3) 		40.5
(2.4) 		43
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 188496_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9167
Sequence Type Exemplar sequence
Representative Public ID T07G12.5 NCBI
Target Description T07G12.5 /REP_DB=WormBase Gene ID /WP=CE13395 /TR=O18057 /GB=CAB05270.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=permease
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069546(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069546 NCBI Caenorhabditis elegans T07G12.5 (permease) mRNA, complete cds. 11/11 None
SNAP00000026258 ENSEMBL cdna:SNAP chromosome:CEL140:IV:10541510:10544981:-1 11/11 None
GENEFINDER00000026269 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:10536708:10544981:-1 11/11 None
T07G12.5 ENSEMBL cdna:known chromosome:CEL140:IV:10541467:10545043:-1 gene:T07G12.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:10541515-10544987(-) 100.0 100.0
Public Domain and Genome References
Gene Title permease
Ensembl T07G12.5
Entrez Gene 177946 Entrez gene
SwissProt O18057 EMBL-EBI
WormBase CE13395 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:12653_AT xanthine/uracil permease family protein at
ATH1-121501:266254_AT xanthine/uracil permease family protein at
CANINE_2:CFAAFFX.5761.1.S1_AT similar to Solute carrier family 23, member 2 (Sodium-dependent vitamin C transporter 2) (mSVCT2) (Na(+)/L-ascorbic acid transporter 2) (Yolk sac permease-like molecule 2) cfa
DROSOPHILA_2:1625688_AT dm
DROSGENOME1:154546_AT dm
MOE430B:1455449_AT gene model 468, (NCBI) mm
MOUSE430_2:1455449_AT gene model 468, (NCBI) mm
MU19KSUBA:TC23864_AT Gene model 468, (NCBI), mRNA (cDNA clone MGC:99995 IMAGE:30541436) mm
RG-U34B:RC_C07059_AT similar to Solute carrier family 23, member 2 (Sodium-dependent vitamin C transporter 2) (mSVCT2) (Na(+)/L-ascorbic acid transporter 2) (Yolk sac permease-like molecule 2) rn
RG-U34C:RC_AA817799_AT similar to Solute carrier family 23, member 2 (Sodium-dependent vitamin C transporter 2) (mSVCT2) (Na(+)/L-ascorbic acid transporter 2) (Yolk sac permease-like molecule 2) rn
RAE230B:1380105_AT similar to Solute carrier family 23, member 2 (Sodium-dependent vitamin C transporter 2) (mSVCT2) (Na(+)/L-ascorbic acid transporter 2) (Yolk sac permease-like molecule 2) rn
RAT230_2:1380105_AT similar to Solute carrier family 23, member 2 (Sodium-dependent vitamin C transporter 2) (mSVCT2) (Na(+)/L-ascorbic acid transporter 2) (Yolk sac permease-like molecule 2) rn
RG-U34C:C07059_AT Similar to Solute carrier family 23, member 2 (Sodium-dependent vitamin C transporter 2) (mSVCT2) (Na(+)/L-ascorbic acid transporter 2) (Yolk sac permease-like molecule 2) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6810 transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5215 transporter activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB05270 Hypothetical protein T07G12.5 [Caenorhabditis elegans] ref|NP_501947.1| T07G12.5 [Caenorhabditis elegans] 0.0
blast CAE63814 Hypothetical protein CBG08364 [Caenorhabditis briggsae] 0.0
blast CAE63817 Hypothetical protein CBG08367 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR006043 EMBL-EBI Xanthine/uracil/vitamin C permease family 1.0E-126
Pfam IPR006043 EMBL-EBI Xanthine/uracil/vitamin C permease family 2.2E-66
Pfam IPR006043 EMBL-EBI Xanthine/uracil/vitamin C permease family 8.1E-68
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_501947.1 11 20-39,52-74,116-138,143-165,169-191,212-234,319-341,362-381,385-402,415-433,448-467
T07G12.5 11 20-39,52-74,116-138,143-165,169-191,212-234,319-341,362-381,385-402,415-433,448-467
SNAP00000026258 11 20-39,52-74,116-138,143-165,169-191,212-234,319-341,362-381,385-402,415-433,448-467
GENEFINDER00000026269 21 20-39,52-74,116-138,143-165,169-191,212-234,319-341,362-381,385-402,415-433,448-467,555-577,582-599,606-625,650-672,707-729,772-794,815-834,838-857,870-887,902-924
Sequence
Target Sequence 
>C. ELEGANS:188496_S_AT
gtcggtcacaaaggtcacaagtcgtatcacaatgcaaatggcgggagttttcctgattct
cgctggcgtcatctcaaagttcgcagcatttttatcaatgattcccgaaccgatcatcgg
cggactacttgccatgggagtatgtcttattaatggagtatcgttgagcaacttacaaac
cgtggatatgaagctatccagaaatttaacaattatcggtgtttcaattatcatgggatt
gacggtggcaacgcatttcgagaagactcccttaaatacaggaaatcaaatagttgatga
tgtattcggaacactactgacaatcagaatgctcatcggtggggtcatagcatttgtgct
agacaatataactggtggtgctacccgaagacagcgtggatttgtttctgaaattgatga
agacgatgatgttgaagaacaggcaactgtggaaatgaatggatatgcacttccatctaa
actcaatcaatttttcttgagatactcatggctcacatacttacc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTCGGTCACAAAGGTCACAAGTCGT 188 473 1053 Antisense
AATGGCGGGAGTTTTCCTGATTCTC 484 161 1089 Antisense
GCTGGCGTCATCTCAAAGTTCGCAG 247 295 1114 Antisense
GATTCCCGAACCGATCATCGGCGGA 429 433 1152 Antisense
CATCGGCGGACTACTTGCCATGGGA 102 211 1167 Antisense
GGGATTGACGGTGGCAACGCATTTC 273 497 1287 Antisense
AACGCATTTCGAGAAGACTCCCTTA 528 145 1302 Antisense
GAATGCTCATCGGTGGGGTCATAGC 78 331 1379 Antisense
TGGTGCTACCCGAAGACAGCGTGGA 644 549 1428 Antisense
ATGCACTTCCATCTAAACTCAATCA 466 43 1517 Antisense
GATACTCATGGCTCACATACTTACC 93 425 1553 Antisense
Sequence Source Affymetrix Proprietary Database