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[188471_at] helicase

Description M03C11.8 /REP_DB=WormBase Gene ID /WP=CE16277 /TR=O45609 /GB=CAA88960.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=helicase
Cluster 6grp_total > 18      4grp_total > 55      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 114
1 2 3 4 range
A 86.6
(3)
P 		16
(-3)
A 		65
(1.2)
A 		20
(-2.7)
A 		71
B 95.5
(3)
P 		87.8
(2.2)
A 		36.8
(-3)
A 		52.8
(-1.4)
A 		59
C 128.2
(3)
P 		14.3
(-3)
A 		85.9
(0.8)
A 		109.3
(2)
A 		114
avr 103.4
(3) 		39.4
(-3) 		62.6
(-0.8) 		60.7
(-1) 		64

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 140
1 2 3 4 5 6 range
A 95.1
(0.1)
A 		96.8
(0.3)
P 		66.5
(-3)
P 		121
(3)
M 		90.7
(-0.3)
A 		92.2
(-0.2)
P 		55
B 60
(-3)
A 		65.3
(-2.2)
A 		62.4
(-2.7)
P 		73.4
(-1.1)
A 		66.9
(-2)
P 		101.9
(3)
A 		42
C 197.4
(3)
P 		74.7
(-2.3)
P 		118.3
(-0.4)
P 		57.2
(-3)
A 		85.6
(-1.8)
P 		73.3
(-2.3)
P 		140
avr 117.5
(3) 		78.9
(-3) 		82.4
(-2.5) 		83.9
(-2.2) 		81.1
(-2.7) 		89.1
(-1.4) 		39
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 40
1 2 3 4 range
A 31.5
(3)
P 		3.5
(-2.9)
A 		17
(-0)
A 		2.9
(-3)
A 		29
B 30.5
(3)
P 		21.7
(0.6)
A 		8.5
(-3)
A 		11.3
(-2.2)
A 		22
C 42.4
(3)
P 		4.1
(-3)
A 		30
(1.1)
A 		18.4
(-0.8)
A 		38
avr 34.8
(3) 		9.8
(-3) 		18.5
(-0.9) 		10.9
(-2.7) 		25

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 62
1 2 3 4 5 6 range
A 17.5
(-2.1)
A 		34.4
(3)
P 		14.5
(-3)
P 		30.7
(1.9)
M 		27.4
(0.9)
A 		22.5
(-0.6)
P 		20
B 20.9
(-1.5)
A 		21.7
(-1.3)
A 		15.1
(-3)
P 		19.4
(-1.9)
A 		27.2
(0.2)
P 		38
(3)
A 		23
C 73.2
(3)
P 		22.8
(-1.9)
P 		30.1
(-1.2)
P 		11.5
(-3)
A 		27.7
(-1.4)
P 		24.5
(-1.7)
P 		62
avr 37.2
(3) 		26.3
(-0.8) 		19.9
(-3) 		20.5
(-2.8) 		27.4
(-0.4) 		28.3
(-0.1) 		17
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188471_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.7488
Sequence Type Exemplar sequence
Representative Public ID M03C11.8 NCBI
Target Description M03C11.8 /REP_DB=WormBase Gene ID /WP=CE16277 /TR=O45609 /GB=CAA88960.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=helicase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066900(10)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066900 NCBI Caenorhabditis elegans M03C11.8 (helicase) mRNA, complete cds. 10/11 None
M03C11.8 ENSEMBL cdna:known chromosome:CEL140:III:10428238:10435865:-1 gene:M03C11.8 10/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000000551 3/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:10428702-10435861(-) 96.66 100.0
Public Domain and Genome References
Gene Title helicase
Ensembl M03C11.8
Entrez Gene 176462 Entrez gene
SwissProt O45609 EMBL-EBI
WormBase CE34059 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:17818_AT SNF2 domain-containing protein / helicase domain-containing protein at
ATH1-121501:266122_AT SNF2 domain-containing protein / helicase domain-containing protein at
CANINE:1606025_AT similar to SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 cfa
CANINE:1602463_AT similar to SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 cfa
CANINE_2:CFA.1741.1.S1_S_AT similar to SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 cfa
CANINE_2:CFA.9945.1.A1_AT similar to SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 cfa
CANINE_2:CFAAFFX.15733.1.S1_AT similar to SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 cfa
DROSOPHILA_2:1624673_AT dm
DROSGENOME1:151787_AT dm
CHICKEN:GGAAFFX.23225.1.S1_S_AT similar to hypothetical protein DKFZp762K2015 gga
HU35KSUBB:RC_W74507_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 hs
HU35KSUBD:RC_R59694_S_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 hs
HU35KSUBD:RC_AA446100_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 hs
U133_X3P:HS.21356.0.S1_3P_A_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 hs
HG-U133_PLUS_2:223197_S_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 hs
HG-U133B:223197_S_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 hs
HG-U95B:49457_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 hs
HG-U95B:56209_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 hs
HG-U95C:56522_R_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 hs
HG-U95D:76202_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 hs
HG-U95D:78837_R_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 hs
MU11KSUBB:X69942_S_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` mm
MG-U74AV2:98991_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` mm
MG-U74AV2:161920_R_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` mm
MOE430A:1435651_A_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` mm
MOUSE430A_2:1435651_A_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` mm
MOUSE430_2:1435651_A_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` mm
MOE430A:1452276_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` mm
MOUSE430A_2:1452276_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` mm
MOUSE430_2:1452276_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` mm
MG-U74CV2:165645_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` mm
MU19KSUBC:TC38281_S_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` mm
MOE430B:1440066_AT MRNA of enhancer-trap-locus 1 mm
MOUSE430_2:1440066_AT MRNA of enhancer-trap-locus 1 mm
MU19KSUBA:TC18070_S_AT MRNA of enhancer-trap-locus 1 mm
RAE230B:1384851_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` (predicted) rn
RAT230_2:1384851_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` (predicted) rn
RAE230A:1377012_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` (predicted) rn
RAT230_2:1377012_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` (predicted) rn
RAE230A:1390629_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` (predicted) rn
RAT230_2:1390629_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` (predicted) rn
RAE230B:1397253_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` (predicted) rn
RAT230_2:1397253_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` (predicted) rn
RG-U34C:RC_AI236127_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` (predicted) rn
RG-U34B:RC_AA965085_AT SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` (predicted) rn
YEAST_2:1779662_AT Protein whose overexpression affects chromosome stability, potential Cdc28p substrate; homolog of Snf2p Sc
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
3676 nucleic acid binding inferred from electronic annotation QuickGO AmiGO
3677 DNA binding inferred from electronic annotation QuickGO AmiGO
4386 helicase activity inferred from electronic annotation QuickGO AmiGO
5509 calcium ion binding inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
8026 ATP-dependent helicase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA88960 Hypothetical protein M03C11.8 [Caenorhabditis elegans] emb|CAA15960.2| Hypothetical protein M03C11.8 [Caenorhabditis elegans] ref|NP_499301.2| M03C11.8 [Caenorhabditis elegans] 0.0
blast CAE71470 Hypothetical protein CBG18388 [Caenorhabditis briggsae] 0.0
blast NP_001015697 MGC108253 protein [Xenopus tropicalis] gb|AAH89242.1| MGC108253 protein [Xenopus tropicalis] 1.0E-139
Protein Domains
Database ID Description E-Value
Pfam IPR000330 EMBL-EBI SNF2 related domain 1.9E-84
Pfam IPR001650 EMBL-EBI Helicase, C-terminal 4.5E-26
Sequence
Target Sequence 
>C. ELEGANS:188471_AT
gccggtggacttggaattaatctcacatcggctaatcatatcatcattcatgatattgat
ttcaacccgtataacgataaacaggcagaggacagatgtcatcgtatgggacaggaaaag
cctgtgcatgtcactcggcttgtgagtaagggtactgtagaagttggaatgttggcgttg
gcgaagaagaagttgcaattggagaaacaggttaccgatggtgtcaagggacagttggat
gaagtacatttcattgaaaactttaagtttttgttagaagaaatcgaaatttaccgaaaa
tttcgaaaattcgaccttttcaaaagtccaaatattccagaaattcaaaaaaaaaaatca
aagaactctgatttttttacaggaaaaaaatacgccctccgtgagctgaaagaagaagaa
ggcggtgaacaatgcggtggccgtgatctaagtaaacttctttcatcggcgatcagt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCCGGTGGACTTGGAATTAATCTCA 574 283 2500 Antisense
TAATCTCACATCGGCTAATCATATC 453 635 2517 Antisense
TATTGATTTCAACCCGTATAACGAT 14 665 2553 Antisense
GGAAAAGCCTGTGCATGTCACTCGG 275 525 2613 Antisense
GTGCATGTCACTCGGCTTGTGAGTA 460 477 2623 Antisense
GAAGTTGGAATGTTGGCGTTGGCGA 226 337 2659 Antisense
GAAACAGGTTACCGATGGTGTCAAG 1 353 2703 Antisense
TACGCCCTCCGTGAGCTGAAAGAAG 681 647 2890 Antisense
GGCGGTGAACAATGCGGTGGCCGTG 441 513 2920 Antisense
GGTGGCCGTGATCTAAGTAAACTTC 71 499 2935 Antisense
TAAACTTCTTTCATCGGCGATCAGT 63 641 2952 Antisense
Sequence Source Affymetrix Proprietary Database