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[188438_s_at] Profilin

Description K03E6.6 /REP_DB=WormBase Gene ID /WP=CE07332 /TR=Q21193 /GB=AAC69045.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=Profilin
Cluster 6grp_highest_10_10 > 05      6grp_high1_10_10 > 41      4grp_highest_8_8 > 09      4grp_high_8_8 > 54      6grp_highest_nonorm > 43      6grp_total > 31      4grp_total > 58      6grp_highest_sub > 03_04      6grp_cgc > 83      6grp_high1_sub > 03      6grp_cgc_sub > 03      6grp_total_sub > Hat      6grp_rule_based > S3      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1460
1 2 3 4 range
A 497.9
(-1.7)
P 		1631.3
(3)
P 		1485.4
(2.4)
P 		171.1
(-3)
P 		1460
B 603.3
(-1.5)
P 		1423.9
(2.2)
P 		1606.6
(3)
P 		256.8
(-3)
P 		1350
C 552.2
(-1.4)
P 		1510.8
(3)
P 		1403.2
(2.5)
P 		200
(-3)
P 		1311
avr 551.1
(-1.4) 		1522
(3) 		1498.4
(2.9) 		209.3
(-3) 		1313

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1102
1 2 3 4 5 6 range
A 1010.7
(0.2)
P 		1158.3
(1)
P 		1508.2
(3)
P 		1131.2
(0.9)
P 		888.1
(-0.5)
P 		441
(-3)
P 		1067
B 930.7
(-0.6)
P 		1264.3
(1.4)
P 		1542.7
(3)
P 		1222.7
(1.1)
P 		895.1
(-0.8)
P 		523.4
(-3)
P 		1019
C 1116.6
(1.8)
P 		1270.8
(3)
P 		1204.3
(2.5)
P 		1194.1
(2.4)
P 		869.4
(-0.2)
P 		529.1
(-3)
P 		742
avr 1019.3
(0.4) 		1231.1
(1.8) 		1418.4
(3) 		1182.7
(1.5) 		884.2
(-0.5) 		497.8
(-3) 		921
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 464
1 2 3 4 range
A 181.3
(-0.4)
P 		354.1
(2.4)
P 		388.3
(3)
P 		25
(-3)
P 		363
B 192.4
(-0.4)
P 		351.7
(2.6)
P 		372.3
(3)
P 		54.7
(-3)
P 		318
C 182.8
(-1)
P 		434.4
(2.3)
P 		489
(3)
P 		33.7
(-3)
P 		455
avr 185.5
(-0.7) 		380.1
(2.4) 		416.5
(3) 		37.8
(-3) 		379

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 313
1 2 3 4 5 6 range
A 186.3
(-1.4)
P 		412
(3)
P 		328.4
(1.4)
P 		286.9
(0.5)
P 		268
(0.2)
P 		107.4
(-3)
P 		305
B 323.8
(0.4)
P 		420.8
(3)
P 		374.6
(1.8)
P 		323.9
(0.4)
P 		363.7
(1.5)
P 		195.2
(-3)
P 		226
C 413.9
(3)
P 		387.8
(2.3)
P 		306.5
(0.3)
P 		240.1
(-1.4)
P 		281.3
(-0.4)
P 		177.1
(-3)
P 		237
avr 308
(0.6) 		406.9
(3) 		336.5
(1.3) 		283.6
(0) 		304.3
(0.5) 		159.9
(-3) 		247
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 188438_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18346
Sequence Type Exemplar sequence
Representative Public ID K03E6.6 NCBI
Target Description K03E6.6 /REP_DB=WormBase Gene ID /WP=CE07332 /TR=Q21193 /GB=AAC69045.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=Profilin
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_075804(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_075804 NCBI Caenorhabditis elegans K03E6.6 (Profilin) mRNA, complete cds. 11/11 None
SNAP00000010592 ENSEMBL cdna:SNAP chromosome:CEL140:X:1079543:1080622:-1 11/11 None
GENEFINDER00000010598 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:1079543:1080622:-1 11/11 None
K03E6.6 ENSEMBL cdna:known chromosome:CEL140:X:1079489:1080622:-1 gene:K03E6.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:1079542-1080622(-) 100.0 100.0
Public Domain and Genome References
Gene Title Profilin
Gene Symbol pfn-3
Ensembl K03E6.6
Entrez Gene 180460 Entrez gene
SwissProt Q21193 EMBL-EBI
WormBase CE07332 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:12411_S_AT profilin 4 (PRO4) (PFN4) at
ATH1-121501:266697_AT profilin 4 (PRO4) (PFN4) at
DROSOPHILA_2:1640251_S_AT chickadee dm
DROSGENOME1:153858_AT chickadee dm
YEAST_2:1774161_AT Profilin, actin- and phosphatidylinositol 4,5-bisphosphate-binding protein, plays a role in cytoskeleton organization, required for normal timing of actin polymerization in response to thermal stress; localizes to plasma membrane and cytosol Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7010 cytoskeleton organization and biogenesis inferred from electronic annotation QuickGO AmiGO
30036 actin cytoskeleton organization and biogenesis inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
15629 actin cytoskeleton inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3779 actin binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC69045 Profilin protein 3 [Caenorhabditis elegans] ref|NP_508205.1| K03E6.6 [Caenorhabditis elegans] sp|Q21193|PROF3_CAEEL Profilin-3 gb|AAT01435.1| profilin-3 [Caenorhabditis elegans] 7.0E-66
blast CAE63575 Hypothetical protein CBG08063 [Caenorhabditis briggsae] 1.0E-58
blast EAL39221 ENSANGP00000029546 [Anopheles gambiae str. PEST] ref|XP_553744.1| ENSANGP00000029546 [Anopheles gambiae str. PEST] 1.0E-20
Protein Domains
Database ID Description E-Value
Pfam IPR002097 EMBL-EBI Profilin/allergen 2.0E-31
Sequence
Target Sequence 
>C. ELEGANS:188438_S_AT
caacaataaccttatcgggtctggaaatgtgagcaaggctgccattcttggattcgacgg
agctgtatgggcaaagagtgataactttaatatctccgtcgaagaagccgtcgccgcagg
aaaagccttcacctccttggatgctcttcttggaaccggcctccgcttggaaggacaaaa
attcttggtcctcaacgcagataatgacagaataattggaaagcaaggaggatctggatt
tttcatctacaaaactatccaagccgttattatttccatctacgagaaaggactccaacc
agaaatgtgcagcaagaccaccggagc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CAACAATAACCTTATCGGGTCTGGA 245 189 33 Antisense
AAATGTGAGCAAGGCTGCCATTCTT 231 121 57 Antisense
GCCATTCTTGGATTCGACGGAGCTG 85 281 73 Antisense
GACGGAGCTGTATGGGCAAAGAGTG 48 375 88 Antisense
AAATTCTTGGTCCTCAACGCAGATA 423 115 211 Antisense
GGAGGATCTGGATTTTTCATCTACA 157 517 259 Antisense
CATCTACAAAACTATCCAAGCCGTT 297 211 276 Antisense
CCAAGCCGTTATTATTTCCATCTAC 187 277 291 Antisense
TTCCATCTACGAGAAAGGACTCCAA 32 697 306 Antisense
AGGACTCCAACCAGAAATGTGCAGC 328 55 321 Antisense
AAATGTGCAGCAAGACCACCGGAGC 202 121 335 Antisense
Sequence Source Affymetrix Proprietary Database