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[188362_at]

Description C34D4.12 /REP_DB=WormBase Gene ID /WP=CE17506 /GEN=cyp-12 /TR=Q18445 /GB=AAB00697.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 87      6grp_high1_10_10 > 78      4grp_highest_8_8 > 01      4grp_high_8_8 > 53      6grp_highest_nonorm > 96      6grp_total > 78      4grp_total > 50      6grp_highest_sub > Da      6grp_cgc > 49      6grp_high1_sub > Cu      6grp_cgc_sub > Da      6grp_total_sub > Increase      6grp_rule_based > S6      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 593
1 2 3 4 range
A 812.1
(-0.4)
P 		881.4
(1.2)
P 		965.5
(3)
P 		691.4
(-3)
P 		274
B 660.6
(-3)
P 		877.9
(3)
P 		863.6
(2.6)
P 		707.9
(-1.7)
P 		217
C 851.9
(-0.7)
P 		1212.9
(3)
P 		960.6
(0.4)
P 		619.6
(-3)
P 		593
avr 774.9
(-1.1) 		990.7
(3) 		929.9
(1.9) 		673
(-3) 		318

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 702
1 2 3 4 5 6 range
A 795.9
(-0.4)
P 		590.6
(-3)
P 		755.4
(-0.9)
P 		620.9
(-2.6)
P 		809.7
(-0.3)
P 		1069
(3)
P 		478
B 769.4
(-1.9)
P 		927.4
(-0.4)
P 		846.9
(-1.1)
P 		648
(-3)
P 		1047.8
(0.7)
P 		1292.1
(3)
P 		644
C 632.1
(-2.7)
P 		711.7
(-1.9)
P 		597.2
(-3)
P 		796.6
(-1)
P 		850.8
(-0.5)
P 		1203.5
(3)
P 		606
avr 732.5
(-2.5) 		743.2
(-2.3) 		733.2
(-2.5) 		688.5
(-3) 		902.8
(-0.4) 		1188.2
(3) 		500
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 248
1 2 3 4 range
A 295.7
(3)
P 		191.3
(-0.2)
P 		252.4
(1.7)
P 		101.2
(-3)
P 		195
B 210.6
(2.4)
P 		216.8
(3)
P 		200.1
(1.5)
P 		150.9
(-3)
P 		66
C 282
(1.4)
P 		348.7
(3)
P 		334.8
(2.7)
P 		104.5
(-3)
P 		244
avr 262.8
(3) 		252.3
(2.6) 		262.4
(3) 		118.9
(-3) 		144

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 335
1 2 3 4 5 6 range
A 146.7
(-3)
P 		210.1
(0.3)
P 		164.5
(-2.1)
P 		157.5
(-2.4)
P 		244.3
(2.2)
P 		260.3
(3)
P 		114
B 267.7
(-1.1)
P 		308.7
(-0.3)
P 		205.6
(-2.3)
P 		171.6
(-3)
P 		425.7
(1.9)
P 		481.8
(3)
P 		310
C 234.3
(-1)
P 		217.2
(-1.4)
P 		152
(-3)
P 		160.2
(-2.8)
P 		275.3
(-0.1)
P 		402.9
(3)
P 		251
avr 216.2
(-1.5) 		245.3
(-0.7) 		174
(-2.7) 		163.1
(-3) 		315.1
(1.2) 		381.7
(3) 		219
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188362_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8727
Sequence Type Exemplar sequence
Representative Public ID C34D4.12 NCBI
Target Description C34D4.12 /REP_DB=WormBase Gene ID /WP=CE17506 /GEN=cyp-12 /TR=Q18445 /GB=AAB00697.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_068717(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_068717 NCBI Caenorhabditis elegans CYclophyliN family member (cyn-12) (cyn-12) mRNA, complete cds. 11/11 None
SNAP00000003800 ENSEMBL cdna:SNAP chromosome:CEL140:IV:7132207:7133197:-1 11/11 None
GENEFINDER00000003815 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:7132207:7133197:-1 11/11 None
C34D4.12 ENSEMBL cdna:known chromosome:CEL140:IV:7132115:7133197:-1 gene:C34D4.12 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:7132212-7133203(-) 100.0 100.0
Public Domain and Genome References
Gene Title
Gene Symbol cyn-12
Ensembl C34D4.12
Entrez Gene 191627 Entrez gene
SwissProt Q18445 EMBL-EBI
WormBase CE17506 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:12434_AT peptidyl-prolyl cis-trans isomerase, putative / cyclophilin, putative / rotamase, putative at
ATH1-121501:263288_AT peptidyl-prolyl cis-trans isomerase, putative / cyclophilin, putative / rotamase, putative at
CANINE:1590619_AT similar to Peptidyl-prolyl cis-trans isomerase like 1 (PPIase) (Rotamase) cfa
CANINE:1586616_AT similar to Peptidyl-prolyl cis-trans isomerase like 1 (PPIase) (Rotamase) cfa
CANINE_2:CFA.12015.1.S1_AT similar to Peptidyl-prolyl cis-trans isomerase like 1 (PPIase) (Rotamase) cfa
CANINE_2:CFA.9641.1.A1_AT similar to Peptidyl-prolyl cis-trans isomerase like 1 (PPIase) (Rotamase) cfa
CANINE_2:CFAAFFX.3039.1.S1_S_AT similar to Peptidyl-prolyl cis-trans isomerase like 1 (PPIase) (Rotamase) cfa
DROSOPHILA_2:1639357_AT Cyclophilin-like dm
DROSGENOME1:147931_AT Cyclophilin-like dm
HG-U133B:222500_AT peptidylprolyl isomerase (cyclophilin)-like 1 hs
HG-U133_PLUS_2:222500_AT peptidylprolyl isomerase (cyclophilin)-like 1 hs
HU35KSUBA:RC_AA610108_AT peptidylprolyl isomerase (cyclophilin)-like 1 hs
U133_X3P:G12804374_3P_AT peptidylprolyl isomerase (cyclophilin)-like 1 hs
HG-U95B:51169_AT peptidylprolyl isomerase (cyclophilin)-like 1 hs
HG-U95D:75054_AT peptidylprolyl isomerase (cyclophilin)-like 1 hs
HG-U95C:64011_S_AT Peptidylprolyl isomerase (cyclophilin)-like 1 hs
MG-U74BV2:106072_AT peptidylprolyl isomerase (cyclophilin)-like 1 mm
MOE430B:1428892_AT peptidylprolyl isomerase (cyclophilin)-like 1 mm
MOUSE430_2:1428892_AT peptidylprolyl isomerase (cyclophilin)-like 1 mm
MU19KSUBB:TC31671_AT Peptidylprolyl isomerase (cyclophilin)-like 1 (Ppil1), mRNA mm
RG-U34B:RC_AI012397_AT peptidylprolyl isomerase (cyclophilin)-like 1 (predicted) rn
RAE230A:1372517_AT peptidylprolyl isomerase (cyclophilin)-like 1 (predicted) rn
RAT230_2:1372517_AT peptidylprolyl isomerase (cyclophilin)-like 1 (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6457 protein folding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB00697 Cyclophilin family protein 12 [Caenorhabditis elegans] ref|NP_501118.1| CYclophyliN family member (cyn-12) [Caenorhabditis elegans] 1.0E-86
blast CAE61810 Hypothetical protein CBG05777 [Caenorhabditis briggsae] 1.0E-81
blast NP_081121 peptidylprolyl isomerase-like 1 [Mus musculus] gb|AAH58369.1| Peptidylprolyl isomerase-like 1 [Mus musculus] dbj|BAE30513.1| unnamed protein product [Mus musculus] dbj|BAE29731.1| unnamed protein product [Mus musculus] dbj|BAB23265.1| unnamed protein product [Mus musculus] sp|Q9D0W5|PPIL1_MOUSE Peptidyl-prolyl cis-trans isomerase-like 1 (PPIase) (Rotamase) 3.0E-52
Protein Domains
Database ID Description E-Value
Pfam IPR002130 EMBL-EBI Peptidyl-prolyl cis-trans isomerase, cyclophilin type 1.5E-72
Sequence
Target Sequence 
>C. ELEGANS:188362_AT
tgccagctccaatcaacgatcaagctccgtacgttattctcgacacaacaatgggaaaaa
ttgctctcgagttgtattggaatcacgctccacgaacttgccaaaatttttcacaattag
caaaacgaaactattacaacggaactattttccatagaattattgccgattttatgattc
agggaggagatccaaccggtacaggccgaggtggtgcttcaatttacggtgacaagtttt
ccgacgaaattgacgagcgtctcaagcacacaggagctggaattttatctatggcaaatg
caggaccaaatactaacggatctcagttcttcataactcttgcaccaacccaacatctcg
atggaaagcacacaatttttggacgagttgccgccggaatgaaggtcattgctaacatgg
gacgtgttgacactgacaatcatgatcgtccaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGCCAGCTCCAATCAACGATCAAGC 149 587 14 Antisense
GATCAAGCTCCGTACGTTATTCTCG 611 421 31 Antisense
GTATTGGAATCACGCTCCACGAACT 619 451 87 Antisense
AGATCCAACCGGTACAGGCCGAGGT 570 65 201 Antisense
CGAGGTGGTGCTTCAATTTACGGTG 325 241 220 Antisense
CGAGCGTCTCAAGCACACAGGAGCT 364 249 267 Antisense
TACTAACGGATCTCAGTTCTTCATA 617 645 324 Antisense
GTTCTTCATAACTCTTGCACCAACC 430 443 339 Antisense
CACCAACCCAACATCTCGATGGAAA 207 203 356 Antisense
ACAATTTTTGGACGAGTTGCCGCCG 556 113 385 Antisense
GACACTGACAATCATGATCGTCCAA 521 367 442 Antisense
Sequence Source Affymetrix Proprietary Database