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[188332_at] gelsolin

Description K06A4.3 /REP_DB=WormBase Gene ID /WP=CE06107 /TR=Q21253 /GB=CAA94782.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=gelsolin
Cluster 6grp_highest_10_10 > 27      6grp_high1_10_10 > 62      4grp_highest_8_8 > 25      4grp_high_8_8 > 59      6grp_highest_nonorm > 44      6grp_total > 62      4grp_total > 60      6grp_highest_sub > 03_04      6grp_high1_sub > 03      6grp_total_sub > Hat      6grp_rule_based > S3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1053
1 2 3 4 range
A 952.1
(2.3)
P 		1063.7
(3)
P 		965.8
(2.4)
P 		150.1
(-3)
P 		914
B 1020
(2.6)
P 		776.5
(1)
P 		1092.2
(3)
P 		125.5
(-3)
P 		967
C 1178
(3)
P 		1029.1
(2)
P 		1053.3
(2.1)
P 		318
(-3)
P 		860
avr 1050
(3) 		956.4
(2.3) 		1037.1
(2.9) 		197.9
(-3) 		852

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2608
1 2 3 4 5 6 range
A 941.9
(-1.6)
P 		1655.2
(0.2)
P 		2412
(2.2)
P 		2739.9
(3)
P 		1576.3
(-0)
P 		418.9
(-3)
P 		2321
B 1020
(-1.7)
P 		1286.8
(-1.1)
P 		3027.1
(3)
P 		2291.2
(1.3)
P 		1869.5
(0.3)
P 		448.9
(-3)
P 		2578
C 1028
(-1.8)
P 		1250.9
(-1.2)
P 		2890.1
(3)
P 		2058.5
(0.9)
P 		1792.9
(0.2)
P 		553.7
(-3)
P 		2336
avr 996.6
(-1.6) 		1397.6
(-0.6) 		2776.4
(3) 		2363.2
(1.9) 		1746.2
(0.3) 		473.8
(-3) 		2303
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 368
1 2 3 4 range
A 346.7
(3)
P 		230.9
(0.9)
P 		252.5
(1.3)
P 		22
(-3)
P 		325
B 325.3
(3)
P 		191.8
(0.3)
P 		253.1
(1.5)
P 		26.7
(-3)
P 		299
C 389.9
(3)
P 		295.9
(1.3)
P 		367.1
(2.6)
P 		53.6
(-3)
P 		336
avr 354
(3) 		239.5
(0.9) 		290.9
(1.8) 		34.1
(-3) 		320

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 658
1 2 3 4 5 6 range
A 173.6
(-2.3)
P 		588.7
(1.9)
P 		525.3
(1.3)
P 		694.9
(3)
P 		475.7
(0.8)
P 		102
(-3)
P 		593
B 354.9
(-1.1)
P 		428.3
(-0.4)
P 		735.1
(2.8)
P 		606.8
(1.5)
P 		759.5
(3)
P 		167.4
(-3)
P 		592
C 381.1
(-0.9)
P 		381.7
(-0.9)
P 		735.6
(3)
P 		414
(-0.5)
P 		580.2
(1.3)
P 		185.4
(-3)
P 		550
avr 303.2
(-1.2) 		466.2
(0.7) 		665.3
(3) 		571.9
(1.9) 		605.1
(2.3) 		151.6
(-3) 		514
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188332_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11693
Sequence Type Exemplar sequence
Representative Public ID K06A4.3 NCBI
Target Description K06A4.3 /REP_DB=WormBase Gene ID /WP=CE06107 /TR=Q21253 /GB=CAA94782.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=gelsolin
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073047(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073047 NCBI Caenorhabditis elegans K06A4.3 (gelsolin) mRNA, complete cds. 11/11 None
SNAP00000041746 ENSEMBL cdna:SNAP chromosome:CEL140:V:9499689:9501857:1 11/11 None
GENEFINDER00000041755 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:9499689:9502422:1 11/11 None
K06A4.3.2 ENSEMBL cdna:known chromosome:CEL140:V:9499164:9501952:1 gene:K06A4.3 11/11 None
K06A4.3.1 ENSEMBL cdna:known chromosome:CEL140:V:9499635:9501952:1 gene:K06A4.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:9499688-9501857(+) 99.79 100.0
Public Domain and Genome References
Gene Title gelsolin
Ensembl K06A4.3
Entrez Gene 179328 Entrez gene
SwissProt Q21253 EMBL-EBI
WormBase CE06107 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:18119_S_AT villin, putative at
ATH1-121501:253663_AT villin, putative at
CANINE:1585067_X_AT similar to Gelsolin precursor (Actin-depolymerizing factor) (ADF) (Brevin) (AGEL) cfa
CANINE:1585066_AT similar to Gelsolin precursor (Actin-depolymerizing factor) (ADF) (Brevin) (AGEL) cfa
CANINE_2:CFA.1238.3.A1_AT similar to Gelsolin precursor (Actin-depolymerizing factor) (ADF) (Brevin) (AGEL) cfa
CANINE_2:CFA.17575.1.S1_S_AT similar to Gelsolin precursor (Actin-depolymerizing factor) (ADF) (Brevin) (AGEL) cfa
CANINE_2:CFAAFFX.6450.1.S1_S_AT similar to Gelsolin precursor (Actin-depolymerizing factor) (ADF) (Brevin) (AGEL) cfa
DROSGENOME1:141697_AT Gelsolin dm
DROSOPHILA_2:1627060_S_AT Gelsolin dm
CHICKEN:GGA.4451.1.S1_AT gelsolin (amyloidosis, Finnish type) gga
HG-U133_PLUS_2:200696_S_AT gelsolin (amyloidosis, Finnish type) hs
HG-U133A:200696_S_AT gelsolin (amyloidosis, Finnish type) hs
HG-FOCUS:200696_S_AT gelsolin (amyloidosis, Finnish type) hs
HG-U133A_2:200696_S_AT gelsolin (amyloidosis, Finnish type) hs
HG-U133_PLUS_2:214040_S_AT gelsolin (amyloidosis, Finnish type) hs
HG-U133A_2:214040_S_AT gelsolin (amyloidosis, Finnish type) hs
HG-U133A:214040_S_AT gelsolin (amyloidosis, Finnish type) hs
HUGENEFL:X04412_AT gelsolin (amyloidosis, Finnish type) hs
U133_X3P:G4504164_3P_A_AT gelsolin (amyloidosis, Finnish type) hs
U133_X3P:HS2.334579.1.S1_3P_X_AT gelsolin (amyloidosis, Finnish type) hs
U133_X3P:HS.290070.3.A1_3P_X_AT gelsolin (amyloidosis, Finnish type) hs
U133_X3P:HS.290070.3.A1_3P_AT gelsolin (amyloidosis, Finnish type) hs
U133_X3P:HS.290070.3.A1_3P_A_AT gelsolin (amyloidosis, Finnish type) hs
HG-U95AV2:32612_AT gelsolin (amyloidosis, Finnish type) hs
HG-U95E:80383_S_AT gelsolin (amyloidosis, Finnish type) hs
HG-U95C:60664_AT Gelsolin (amyloidosis, Finnish type) hs
HG-U95E:86127_AT Gelsolin (amyloidosis, Finnish type) hs
MOUSE430A_2:1456312_X_AT gelsolin mm
MOE430A:1456312_X_AT gelsolin mm
MOUSE430_2:1456312_X_AT gelsolin mm
MU11KSUBA:J04953_F_AT gelsolin mm
MU11KSUBB:MSA.691.0_F_AT gelsolin mm
MG-U74AV2:93750_AT gelsolin mm
MOE430A:1436991_X_AT gelsolin mm
MOUSE430A_2:1436991_X_AT gelsolin mm
MOUSE430_2:1436991_X_AT gelsolin mm
MOE430A:1437171_X_AT gelsolin mm
MOUSE430A_2:1437171_X_AT gelsolin mm
MOUSE430_2:1437171_X_AT gelsolin mm
MOE430A:1456569_X_AT gelsolin mm
MOUSE430A_2:1456569_X_AT gelsolin mm
MOUSE430_2:1456569_X_AT gelsolin mm
MOE430A:1415812_AT gelsolin mm
MOUSE430A_2:1415812_AT gelsolin mm
MOUSE430_2:1415812_AT gelsolin mm
MOUSE430_2:1456568_AT Gelsolin (Gsn), mRNA mm
MOUSE430A_2:1456568_AT Gelsolin (Gsn), mRNA mm
MOE430A:1456568_AT Gelsolin (Gsn), mRNA mm
MG-U74AV2:161967_AT Gelsolin (Gsn), mRNA mm
MU19KSUBB:TC26870_AT Gelsolin (Gsn), mRNA mm
MU19KSUBC:TC39600_F_AT Gelsolin (Gsn), mRNA mm
MU19KSUBC:TC39601_AT Gelsolin (Gsn), mRNA mm
MU19KSUBC:TC39601_G_AT Gelsolin (Gsn), mRNA mm
RG-U34B:RC_AI009484_AT gelsolin rn
RAE230A:1371414_AT gelsolin rn
RAT230_2:1371414_AT gelsolin rn
RG-U34C:RC_AI234960_AT Gelsolin rn
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
3779 actin binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA94782 Hypothetical protein K06A4.3 [Caenorhabditis elegans] ref|NP_505448.1| K06A4.3 [Caenorhabditis elegans] 0.0
blast CAE72179 Hypothetical protein CBG19286 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR007123 EMBL-EBI Gelsolin region 9.5E-14
Pfam IPR007123 EMBL-EBI Gelsolin region 6.1E-7
Pfam IPR007123 EMBL-EBI Gelsolin region 6.5E-7
Pfam IPR007123 EMBL-EBI Gelsolin region 1.5E-16
Sequence
Target Sequence 
>C. ELEGANS:188332_AT
gcaacttgatcccaaggatgccttcattcttgatgcaattaatggtggaatcttcgtctg
gattggacatgaatgtactcttgaagaaagatcgaaggctcttatttgggggcagaacta
tttgaaacagcatcatcttccccgctggacacaagttactagagttctcgaatcagctga
atctactcaattcacccaatggttccgtgattgggttgatgagaaaaagaagaacacatt
cactccactccttttccaagtttccgatgaaagcggtcttcttcatgttgaggaaattgc
aaacttcactcaagaagatcttgatggagatgatgtcatgatcttggatgctttgaattc
catctacgtttgggttggagcaaatgctaatgcaaatgagaagaaagaagcattaaacac
tgcaaagttgtacttggaaaaagataagttgccacgtcacaagaaaacagctattgacac
gatcttccaaggaaaagaaccaccaactttcaagaaattcttcccatcctgggacgat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCAACTTGATCCCAAGGATGCCTTC 701 319 843 Antisense
AGGATGCCTTCATTCTTGATGCAAT 268 55 857 Antisense
GGTGGAATCTTCGTCTGGATTGGAC 179 499 886 Antisense
GATCGAAGGCTCTTATTTGGGGGCA 535 417 932 Antisense
TCCCCGCTGGACACAAGTTACTAGA 298 597 981 Antisense
GAGTTCTCGAATCAGCTGAATCTAC 42 399 1004 Antisense
ATCTACTCAATTCACCCAATGGTTC 382 29 1023 Antisense
GAAAGCGGTCTTCTTCATGTTGAGG 82 359 1111 Antisense
ATGCTTTGAATTCCATCTACGTTTG 13 43 1190 Antisense
AAACAGCTATTGACACGATCTTCCA 354 129 1307 Antisense
GAAATTCTTCCCATCCTGGGACGAT 484 361 1356 Antisense
Sequence Source Affymetrix Proprietary Database