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[188303_s_at] cyclin

Description H14E04.5 /REP_DB=WormBase Gene ID /WP=CE20970 /TR=Q9TYP2 /GB=AAD12812.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=cyclin
Cluster 6grp_highest_10_10 > 98      6grp_high1_10_10 > 89      4grp_highest_8_8 > 51      4grp_high_8_8 > 32      6grp_highest_nonorm > 91      6grp_total > 99      4grp_total > 47      6grp_highest_sub > Cu      6grp_cgc > 79      6grp_high1_sub > Cu      6grp_cgc_sub > Da      6grp_total_sub > Increase      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 203
1 2 3 4 range
A 208.2
(3)
P 		166.9
(-0.3)
P 		133.6
(-3)
P 		148.6
(-1.8)
P 		75
B 321.3
(3)
P 		118
(-3)
P 		148.9
(-2.1)
P 		149.9
(-2.1)
P 		203
C 200.6
(3)
P 		161.7
(-2.1)
P 		179.6
(0.3)
P 		154.7
(-3)
P 		46
avr 243.4
(3) 		148.9
(-3) 		154
(-2.7) 		151.1
(-2.9) 		95

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 186
1 2 3 4 5 6 range
A 234.9
(0.1)
P 		203
(-2.2)
P 		205.6
(-2)
P 		192.4
(-3)
P 		236.5
(0.2)
P 		275.2
(3)
P 		83
B 228.5
(-0.6)
P 		198.9
(-1.7)
P 		166.4
(-3)
P 		195.7
(-1.9)
P 		319.7
(3)
P 		308.4
(2.6)
P 		153
C 203.8
(0.3)
P 		200.9
(0.2)
P 		133.3
(-3)
P 		206.2
(0.4)
P 		261.8
(3)
P 		260.6
(2.9)
P 		129
avr 222.4
(-0.1) 		200.9
(-1.3) 		168.4
(-3) 		198.1
(-1.4) 		272.7
(2.5) 		281.4
(3) 		113
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 81
1 2 3 4 range
A 75.8
(3)
P 		36.2
(-1.4)
P 		34.9
(-1.5)
P 		21.8
(-3)
P 		54
B 102.5
(3)
P 		29.2
(-3)
P 		34.5
(-2.6)
P 		31.9
(-2.8)
P 		73
C 66.4
(3)
P 		46.5
(0)
P 		62.6
(2.4)
P 		26.1
(-3)
P 		40
avr 81.6
(3) 		37.3
(-1.8) 		44
(-1.1) 		26.6
(-3) 		55

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 96
1 2 3 4 5 6 range
A 43.3
(-3)
P 		72.2
(3)
P 		44.8
(-2.7)
P 		48.8
(-1.9)
P 		71.4
(2.8)
P 		67
(1.9)
P 		29
B 79.5
(-0.4)
P 		66.2
(-1.3)
P 		40.4
(-3)
P 		51.8
(-2.2)
P 		129.9
(3)
P 		115
(2)
P 		90
C 75.5
(1.7)
P 		61.3
(0.1)
P 		33.9
(-3)
P 		41.5
(-2.1)
P 		84.7
(2.7)
P 		87.2
(3)
P 		53
avr 66.1
(-0.2) 		66.6
(-0.1) 		39.7
(-3) 		47.4
(-2.2) 		95.3
(3) 		89.7
(2.4) 		56
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 188303_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6076
Sequence Type Exemplar sequence
Representative Public ID H14E04.5 NCBI
Target Description H14E04.5 /REP_DB=WormBase Gene ID /WP=CE20970 /TR=Q9TYP2 /GB=AAD12812.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=cyclin
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_065147(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_065147 NCBI Caenorhabditis elegans H14E04.5 (cyclin) mRNA, complete cds. 11/11 None
SNAP00000039215 ENSEMBL cdna:SNAP chromosome:CEL140:III:2383795:2400954:-1 11/11 None
GENEFINDER00000039216 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:2394391:2401196:-1 10/11 None
H14E04.5 ENSEMBL cdna:known chromosome:CEL140:III:2394376:2401271:-1 gene:H14E04.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:2394390-2401196(-) 92.78 100.0
Public Domain and Genome References
Gene Title cyclin
Gene Symbol cic-1
Ensembl H14E04.5
Entrez Gene 175357 Entrez gene
SwissProt Q9TYP2 EMBL-EBI
WormBase CE34571 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:248666_AT cyclin family protein at
CANINE:1604601_AT similar to Cyclin C cfa
CANINE_2:CFA.389.1.S1_AT similar to Cyclin C cfa
CANINE_2:CFAAFFX.6224.1.S1_S_AT similar to Cyclin C cfa
CANINE_2:CFAAFFX.6227.1.S1_AT similar to Cyclin C cfa
CANINE_2:CFAAFFX.6227.1.S1_S_AT similar to Cyclin C cfa
DROSOPHILA_2:1630405_AT Cyclin C dm
DROSGENOME1:154741_AT Cyclin C dm
CHICKEN:GGA.9076.1.S1_A_AT cyclin C gga
CHICKEN:GGAAFFX.11563.1.S1_S_AT cyclin C gga
HG-U95AV2:1923_AT cyclin C hs
HC-G110:1923_AT cyclin C hs
HUGENEFL:M74091_AT cyclin C hs
U133_X3P:HS2.382730.1.S1_3P_AT cyclin C hs
U133_X3P:HS.118442.0.A2_3P_AT cyclin C hs
HG-U133_PLUS_2:1569126_AT cyclin C hs
HG-U133A_2:201955_AT cyclin C hs
HG-FOCUS:201955_AT cyclin C hs
HG-U133_PLUS_2:201955_AT cyclin C hs
HG-U133A:201955_AT cyclin C hs
HG-U95AV2:39251_AT cyclin C hs
HG-U95D:74582_S_AT cyclin C hs
HG-U95D:81732_AT cyclin C hs
HG-U95E:88037_AT cyclin C hs
HU35KSUBD:RC_AA609983_AT Cyclin C hs
U133_X3P:HS.112797.0.A1_3P_AT Cyclin C hs
HG-U133_PLUS_2:244212_AT Cyclin C hs
HG-U133B:244212_AT Cyclin C hs
HG-U95B:42458_AT Cyclin C hs
HG-U133_PLUS_2:242805_AT Cyclin C hs
HG-U133B:242805_AT Cyclin C hs
HG-U95D:84536_R_AT Cyclin C hs
U133_X3P:HS.270881.0.A1_3P_AT Cyclin C hs
MOUSE430_2:1428570_AT cyclin C mm
MOUSE430A_2:1428570_AT cyclin C mm
MOE430A:1428570_AT cyclin C mm
MOUSE430_2:1454144_A_AT cyclin C mm
MOE430A:1454144_A_AT cyclin C mm
MOUSE430A_2:1454144_A_AT cyclin C mm
MU11KSUBA:U62638_S_AT cyclin C mm
MG-U74AV2:99558_AT cyclin C mm
MG-U74BV2:163406_AT cyclin C mm
MOE430A:1417861_AT cyclin C mm
MOUSE430A_2:1417861_AT cyclin C mm
MOUSE430_2:1417861_AT cyclin C mm
MOUSE430_2:1454336_AT Cyclin C (Ccnc), mRNA mm
MOE430B:1454336_AT Cyclin C (Ccnc), mRNA mm
RT-U34:D14013_AT cyclin C rn
RG-U34A:D14013_AT cyclin C rn
RAE230A:1389101_AT cyclin C rn
RAT230_2:1389101_AT cyclin C rn
RAE230A:1390343_AT Cyclin C rn
RAT230_2:1390343_AT Cyclin C rn
RG-U34B:RC_AA998893_AT Cyclin C rn
Protein Similarities
Method ID Description E-Value
blast AAD12812 Cyclin c protein 1 [Caenorhabditis elegans] ref|NP_497548.2| H14E04.5 [Caenorhabditis elegans] 1.0E-165
blast AAD12812 Cyclin c protein 1 [Caenorhabditis elegans] ref|NP_497548.2| H14E04.5 [Caenorhabditis elegans] 1.0E-158
blast CAE69461 Hypothetical protein CBG15657 [Caenorhabditis briggsae] 1.0E-139
blast AAD12812 Cyclin c protein 1 [Caenorhabditis elegans] ref|NP_497548.2| H14E04.5 [Caenorhabditis elegans] 1.0E-134
blast CAE69461 Hypothetical protein CBG15657 [Caenorhabditis briggsae] 1.0E-132
blast CAE69461 Hypothetical protein CBG15657 [Caenorhabditis briggsae] 1.0E-111
blast XP_395475 PREDICTED: similar to ENSANGP00000013964 [Apis mellifera] 3.0E-52
Protein Domains
Database ID Description E-Value
Pfam IPR006671 EMBL-EBI Cyclin, N-terminal domain 2.7E-5
Pfam IPR006671 EMBL-EBI Cyclin, N-terminal domain 2.7E-5
Sequence
Target Sequence 
>C. ELEGANS:188303_S_AT
gagtgacatttgagacgacatcgacaaaaaatggagttgtctacgattccgagtttattc
tcgttgaaattcttgattgttgccttgttgtacatcatgcatcacgtccaatgtgccccc
ccccccccccccgggaaatttttgataaaaactggaacagtggaatttttttgatttttt
ttttgaattttttggtgaaaaaaatggaaaattgtggaatttttagtgaaaaattggaaa
attttgaatttttcaatctggaagcaattgaagctcaatgtcaaaaagtggcaaatgatt
cgctaagatgtgatgtttcattgatttttccaccacatgtcattggattatcaagtatta
tggttgcaatggaattaatgggccgtggagaagaattggaagcttggcttgtcgaagttg
acactgattttgaaaaggtaaccgactgcgttgagcaaatctacaaaatgtacacacttt
ggaagtcatttgatgagaaagaagaagtgaagaagttgatggcgaaattgccgaaaccga
atcagcaaccgcc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAGTGACATTTGAGACGACATCGAC 514 401 401 Antisense
TGTCTACGATTCCGAGTTTATTCTC 35 667 438 Antisense
GTTTATTCTCGTTGAAATTCTTGAT 592 449 453 Antisense
ATTCTTGATTGTTGCCTTGTTGTAC 597 11 469 Antisense
GTTGTACATCATGCATCACGTCCAA 444 437 487 Antisense
GTGGCAAATGATTCGCTAAGATGTG 239 491 688 Antisense
CATTGATTTTTCCACCACATGTCAT 57 217 719 Antisense
GGAAGCTTGGCTTGTCGAAGTTGAC 377 531 798 Antisense
AAAGGTAACCGACTGCGTTGAGCAA 654 121 834 Antisense
GTTGATGGCGAAATTGCCGAAACCG 308 439 915 Antisense
TGCCGAAACCGAATCAGCAACCGCC 454 585 929 Antisense
Sequence Source Affymetrix Proprietary Database