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[188224_s_at] carboxylesterase /// carboxylesterase

Description C52A10.2 /REP_DB=WormBase Gene ID /WP=CE17583 /GB=AAK68262.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=carboxylesterase
Cluster 6grp_high1_10_10 > 85      6grp_total > 76      4grp_total > 12      6grp_total_sub > Increase      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 78
1 2 3 4 range
A 50.5
(-2.6)
P 		51.9
(-2.4)
A 		46.6
(-3)
A 		101.9
(3)
P 		55
B 39.3
(2.7)
P 		40.2
(3)
A 		29.4
(-0.9)
A 		23.6
(-3)
A 		17
C 48.4
(-0.9)
A 		26.3
(-3)
A 		28.1
(-2.8)
A 		89.3
(3)
P 		63
avr 46.1
(-1.1) 		39.5
(-2.2) 		34.7
(-3) 		71.6
(3) 		37

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 191
1 2 3 4 5 6 range
A 66.6
(-3)
A 		106.1
(-1.6)
P 		99.1
(-1.9)
P 		114.4
(-1.3)
P 		87.4
(-2.3)
P 		238.2
(3)
P 		172
B 70.5
(-2)
P 		47.1
(-3)
P 		117.2
(0)
P 		105.4
(-0.5)
P 		174.3
(2.5)
P 		185.3
(3)
P 		138
C 78.6
(-2.5)
P 		72.5
(-3)
P 		151.6
(3)
P 		135.2
(1.8)
P 		114.3
(0.2)
P 		126.9
(1.1)
P 		79
avr 71.9
(-3) 		75.2
(-2.8) 		122.6
(-0.3) 		118.3
(-0.5) 		125.3
(-0.1) 		183.5
(3) 		112
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 13
1 2 3 4 range
A 18.4
(3)
P 		11.3
(-3)
A 		12.2
(-2.2)
A 		14.9
(0)
P 		7
B 12.5
(3)
P 		9.9
(0.9)
A 		6.8
(-1.6)
A 		5
(-3)
A 		8
C 16
(3)
A 		7.6
(-3)
A 		9.8
(-1.4)
A 		15.1
(2.4)
P 		8
avr 15.6
(3) 		9.6
(-3) 		9.6
(-3) 		11.7
(-0.9) 		6

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 59
1 2 3 4 5 6 range
A 12.3
(-3)
A 		37.7
(0.3)
P 		21.6
(-1.8)
P 		29
(-0.8)
P 		26.4
(-1.1)
P 		58
(3)
P 		46
B 24.5
(-2)
P 		15.7
(-3)
P 		28.5
(-1.6)
P 		27.9
(-1.7)
P 		70.8
(3)
P 		69.1
(2.8)
P 		55
C 29.1
(-0.9)
P 		22.1
(-3)
P 		38.6
(1.9)
P 		27.2
(-1.5)
P 		37
(1.4)
P 		42.5
(3)
P 		20
avr 22
(-3) 		25.2
(-2.4) 		29.6
(-1.7) 		28
(-2) 		44.7
(0.9) 		56.5
(3) 		35
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 188224_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.12188
Sequence Type Exemplar sequence
Representative Public ID C52A10.2 NCBI
Target Description C52A10.2 /REP_DB=WormBase Gene ID /WP=CE17583 /GB=AAK68262.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=carboxylesterase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_071997(11), NM_072000(9)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_071997 NCBI Caenorhabditis elegans C52A10.2 (carboxylesterase) mRNA, complete cds. 11/11 None
NM_072000 NCBI Caenorhabditis elegans B0238.13 (carboxylesterase) mRNA, complete cds. 9/11 A 
SNAP00000017568 ENSEMBL cdna:SNAP chromosome:CEL140:V:5230331:5236923:-1 11/11 None
SNAP00000038868 ENSEMBL cdna:SNAP chromosome:CEL140:V:5243555:5249374:-1 11/11 None
GENEFINDER00000038878 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:5243435:5247833:-1 11/11 None
C52A10.2 ENSEMBL cdna:known chromosome:CEL140:V:5234657:5236937:-1 gene:C52A10.2 11/11 None
B0238.13 ENSEMBL cdna:known chromosome:CEL140:V:5243541:5247833:-1 gene:B0238.13 9/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000017570 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:5234656-5236923(-) 100.0 100.0
chrV:5243578-5245633(-) 89.39 89.39
Public Domain and Genome References
Gene Title carboxylesterase
carboxylesterase
Ensembl C52A10.2
B0238.13
Entrez Gene 178910 Entrez gene
178913 Entrez gene
SwissProt O16496 EMBL-EBI
Q95YC3 EMBL-EBI
WormBase CE29530 Wormbase
CE29234 Wormbase
Functional Annotations
Ortholog
ID Title Organism
MG-U74BV2:109159_F_AT expressed sequence AU018778 mm
MG-U74BV2:109158_AT expressed sequence AU018778 mm
MOE430A:1424266_S_AT expressed sequence AU018778 mm
MOUSE430A_2:1424266_S_AT expressed sequence AU018778 mm
MOUSE430_2:1424266_S_AT expressed sequence AU018778 mm
MU19KSUBC:TC41127_AT Expressed sequence AU018778 (AU018778), mRNA mm
RAE230A:1370352_AT similar to Liver carboxylesterase B-1 precursor (Liver microsomal carboxylesterase) rn
RAT230_2:1370352_AT similar to Liver carboxylesterase B-1 precursor (Liver microsomal carboxylesterase) rn
Protein Similarities
Method ID Description E-Value
blast AAK68262 Hypothetical protein C52A10.2 [Caenorhabditis elegans] ref|NP_504398.1| C52A10.2 [Caenorhabditis elegans] 0.0
blast AAB65983 Hypothetical protein B0238.1 [Caenorhabditis elegans] ref|NP_504400.1| B0238.1 [Caenorhabditis elegans] 0.0
blast H89045 protein B0238.13 [imported] - Caenorhabditis elegans 0.0
blast AAB65992 Hypothetical protein B0238.13 [Caenorhabditis elegans] ref|NP_504401.1| B0238.13 [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 1.0E-126
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 1.0E-126
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 1.0E-126
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 1.0E-126
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 1.0E-126
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 1.0E-126
Pfam IPR002651 EMBL-EBI Protein of unknown function DUF32 2.5E-28
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 4.6E-122
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
SNAP00000038868 3 11-30,57-79,96-118
Sequence
Target Sequence 
>C. ELEGANS:188224_S_AT
tttgaagacttctatgctggccagaaaacccctcaacaaatgctatcagcagctttgggt
cctgaagttgtaaggaacagggaagaggttgtcaagagagctgcagaatcttatttgaaa
aatggtggaaacgaaaatgaagaaaacattgccaagacattagttgagatatttggagac
tactacttcagtgtgggagcatttgatactgttcgatcacttgtcaagtatggaaatact
gtatatttgtattctttcaattatttcaatccgaacactccaattgtgtttggcaaaaac
aggccgttcaatgcagctaatcatggttctgatttaagatatatttttggagaagggact
ggagagttttcgaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTTGAAGACTTCTATGCTGGCCAGA 630 667 931 Antisense
TTCTATGCTGGCCAGAAAACCCCTC 4 689 940 Antisense
GCCAGAAAACCCCTCAACAAATGCT 652 275 950 Antisense
AACCCCTCAACAAATGCTATCAGCA 701 145 957 Antisense
CAAATGCTATCAGCAGCTTTGGGTC 572 191 967 Antisense
TGGAGACTACTACTTCAGTGTGGGA 496 549 1104 Antisense
GACTACTACTTCAGTGTGGGAGCAT 472 371 1108 Antisense
GTGTGGGAGCATTTGATACTGTTCG 119 489 1121 Antisense
TACTGTATATTTGTATTCTTTCAAT 596 647 1167 Antisense
AGATATATTTTTGGAGAAGGGACTG 65 63 1267 Antisense
GAGAAGGGACTGGAGAGTTTTCGAA 617 389 1280 Antisense
Sequence Source Affymetrix Proprietary Database