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[188047_at]

Description F08G2.6 /REP_DB=WormBase Gene ID /WP=CE19778 /GEN=ins-37 /TR=Q9XVA1 /GB=CAB04062.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation
Cluster 6grp_total > 78      4grp_total > 42      6grp_cgc > 49      6grp_cgc_sub > Da      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 47
1 2 3 4 range
A 6.1
(-3)
A 		48.6
(3)
A 		8.5
(-2.7)
A 		9.2
(-2.6)
A 		43
B 7.1
(0.2)
A 		11.4
(3)
A 		8.5
(1.1)
A 		2.1
(-3)
A 		9
C 4.7
(-3)
A 		7.1
(-2.2)
A 		22.9
(3)
A 		7
(-2.2)
A 		18
avr 6
(-3) 		22.4
(3) 		13.3
(-0.3) 		6.1
(-3) 		16

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 238
1 2 3 4 5 6 range
A 6.2
(-3)
A 		10.3
(-2.9)
A 		6.9
(-3)
A 		14.8
(-2.8)
A 		79.7
(-1.1)
P 		240.5
(3)
P 		234
B 6.2
(-3)
A 		6.3
(-3)
A 		10.2
(-2.9)
A 		33.8
(-2.2)
A 		95.6
(-0.5)
P 		223
(3)
P 		217
C 6.4
(-2.9)
A 		5.5
(-2.9)
A 		4.5
(-3)
A 		2.8
(-3)
A 		91.8
(-0.5)
P 		214.7
(3)
P 		212
avr 6.3
(-3) 		7.4
(-3) 		7.2
(-3) 		17.1
(-2.7) 		89
(-0.7) 		226.1
(3) 		220
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 10
1 2 3 4 range
A 2.2
(-2.4)
A 		10.5
(3)
A 		2.2
(-2.4)
A 		1.3
(-3)
A 		9
B 2.3
(1.7)
A 		2.8
(3)
A 		2
(0.9)
A 		0.5
(-3)
A 		2
C 1.6
(-2.6)
A 		2
(-2.3)
A 		8
(3)
A 		1.2
(-3)
A 		7
avr 2
(-1.5) 		5.1
(3) 		4.1
(1.5) 		1
(-3) 		4

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 83
1 2 3 4 5 6 range
A 1.1
(-3)
A 		3.7
(-2.7)
A 		1.5
(-3)
A 		3.7
(-2.7)
A 		24.1
(-0.6)
P 		58.6
(3)
P 		58
B 2.1
(-3)
A 		2.1
(-3)
A 		2.5
(-3)
A 		8.9
(-2.5)
A 		38.9
(-0.3)
P 		83.2
(3)
P 		81
C 2.4
(-2.8)
A 		1.7
(-2.9)
A 		1.2
(-2.9)
A 		0.6
(-3)
A 		29.7
(-0.6)
P 		71.9
(3)
P 		71
avr 1.9
(-3) 		2.5
(-2.9) 		1.7
(-3) 		4.4
(-2.8) 		30.9
(-0.5) 		71.2
(3) 		70
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188047_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3856
Sequence Type Exemplar sequence
Representative Public ID F08G2.6 NCBI
Target Description F08G2.6 /REP_DB=WormBase Gene ID /WP=CE19778 /GEN=ins-37 /TR=Q9XVA1 /GB=CAB04062.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064501(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_064501 NCBI Caenorhabditis elegans INSulin related family member (ins-37) (ins-37) mRNA, complete cds. 11/11 None
SNAP00000034716 ENSEMBL cdna:SNAP chromosome:CEL140:II:13831274:13835555:-1 11/11 None
GENEFINDER00000034725 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:13834357:13835555:-1 11/11 None
F08G2.6 ENSEMBL cdna:known chromosome:CEL140:II:13835009:13835555:-1 gene:F08G2.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:13835005-13835552(-) 100.0 100.0
Public Domain and Genome References
Gene Title
Gene Symbol ins-37
Ensembl F08G2.6
Entrez Gene 191693 Entrez gene
SwissProt Q9XVA1 EMBL-EBI
WormBase CE19778 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7582 physiological process inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5576 extracellular region inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5179 hormone activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB04062 Hypothetical protein F08G2.6 [Caenorhabditis elegans] ref|NP_496902.1| INSulin related family member (ins-37) [Caenorhabditis elegans] 7.0E-85
blast CAB04062 Hypothetical protein F08G2.6 [Caenorhabditis elegans] ref|NP_496902.1| INSulin related family member (ins-37) [Caenorhabditis elegans] 6.0E-84
blast CAB04062 Hypothetical protein F08G2.6 [Caenorhabditis elegans] ref|NP_496902.1| INSulin related family member (ins-37) [Caenorhabditis elegans] 2.0E-82
blast CAB04059 Hypothetical protein F08G2.5 [Caenorhabditis elegans] ref|NP_496901.1| F08G2.5 [Caenorhabditis elegans] 2.0E-38
Protein Domains
Database ID Description E-Value
Pfam IPR003235 EMBL-EBI Nematode insulin-related peptide, beta type 1.5E-32
Sequence
Target Sequence 
>C. ELEGANS:188047_AT
tttcctgccaattgccttgagcattgctatgctcaccgtgctcaccaatgccaatccaat
tcacccggtcccaaatgcggccttccttccctatcgttcctgtggatcccatcttgttca
tcgcgcttttgaagcttgcagtgggaagaaagatcgcagcagtgatgtggatctttggaa
gatgtgctgcaaggacgagtgtaccgatctggacatcaaggagtctctgtgcaagtacgc
ttcgcaaggatatggagtaaagtttgaggaggaagccgaagaaatcgatatggtcagctt
tgcggcggagggttttaaaaagagctgtggacatgatattgttgtgaagacagtcaatgt
accgacgaaaatatcattgaagcaatgtgcccgaacaagggggtggcgccggcggcctag
aagaatcccggacaagttcaatcgagtgc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTTCCTGCCAATTGCCTTGAGCATT 383 669 21 Antisense
TGAGCATTGCTATGCTCACCGTGCT 173 567 38 Antisense
ATCTTGTTCATCGCGCTTTTGAAGC 44 31 131 Antisense
ATCGCAGCAGTGATGTGGATCTTTG 37 35 173 Antisense
AGATGTGCTGCAAGGACGAGTGTAC 471 65 200 Antisense
GACGAGTGTACCGATCTGGACATCA 382 379 214 Antisense
AGGAGTCTCTGTGCAAGTACGCTTC 186 57 239 Antisense
TCGATATGGTCAGCTTTGCGGCGGA 440 603 305 Antisense
TGTGCCCGAACAAGGGGGTGGCGCC 197 535 406 Antisense
CGGCGGCCTAGAAGAATCCCGGACA 552 203 430 Antisense
ATCCCGGACAAGTTCAATCGAGTGC 22 39 445 Antisense
Sequence Source Affymetrix Proprietary Database