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[188040_at] lipase

Description T12A7.4 /REP_DB=WormBase Gene ID /WP=CE06436 /TR=Q22420 /GB=CAA98139.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=lipase
Cluster 6grp_high1_10_10 > 32      6grp_total > 21      4grp_total > 54      6grp_high1_sub > 02_03      6grp_total_sub > Hat      6grp_rule_based > S3      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 449
1 2 3 4 range
A 453.9
(3)
P 		197.4
(-0.7)
P 		156.7
(-1.3)
P 		34.5
(-3)
A 		419
B 429.5
(3)
P 		243.3
(0.1)
P 		175.4
(-0.9)
P 		39.2
(-3)
A 		390
C 482.5
(3)
P 		167.1
(-1.2)
P 		129.3
(-1.7)
P 		33.1
(-3)
A 		449
avr 455.3
(3) 		202.6
(-0.6) 		153.8
(-1.3) 		35.6
(-3) 		420

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 250
1 2 3 4 5 6 range
A 194.4
(1.9)
P 		208.5
(2.3)
P 		229.8
(3)
P 		114.5
(-0.7)
P 		129
(-0.3)
P 		45.1
(-3)
A 		185
B 129.8
(-1.3)
P 		186.6
(0.2)
P 		294.9
(3)
P 		141.4
(-1)
P 		128.8
(-1.3)
P 		65.3
(-3)
P 		230
C 193.7
(0.4)
P 		283.5
(3)
P 		159.4
(-0.5)
P 		197.2
(0.5)
P 		111.9
(-1.9)
P 		73.4
(-3)
P 		210
avr 172.6
(1) 		226.2
(2.9) 		228
(3) 		151
(0.2) 		123.2
(-0.8) 		61.3
(-3) 		167
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 160
1 2 3 4 range
A 165.3
(3)
P 		42.9
(-1.6)
P 		41
(-1.7)
P 		5
(-3)
A 		160
B 137
(3)
P 		60.1
(-0.6)
P 		40.6
(-1.5)
P 		8.4
(-3)
A 		129
C 159.7
(3)
P 		48
(-1.3)
P 		45.1
(-1.5)
P 		5.6
(-3)
A 		154
avr 154
(3) 		50.3
(-1.2) 		42.2
(-1.5) 		6.3
(-3) 		148

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 76
1 2 3 4 5 6 range
A 35.8
(-0.6)
P 		74.1
(3)
P 		50.1
(0.7)
P 		29
(-1.3)
P 		38.9
(-0.3)
P 		11
(-3)
A 		63
B 45.2
(-0.4)
P 		62.1
(1.8)
P 		71.6
(3)
P 		37.4
(-1.3)
P 		52.3
(0.5)
P 		24.4
(-3)
P 		47
C 71.8
(1.6)
P 		86.5
(3)
P 		40.6
(-1.4)
P 		39.7
(-1.5)
P 		36.2
(-1.9)
P 		24.6
(-3)
P 		62
avr 50.9
(0.4) 		74.2
(3) 		54.1
(0.8) 		35.4
(-1.3) 		42.5
(-0.5) 		20
(-3) 		54
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188040_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9316
Sequence Type Exemplar sequence
Representative Public ID T12A7.4 NCBI
Target Description T12A7.4 /REP_DB=WormBase Gene ID /WP=CE06436 /TR=Q22420 /GB=CAA98139.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=lipase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069829(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069829 NCBI Caenorhabditis elegans T12A7.4 (lipase) mRNA, complete cds. 11/11 None
SNAP00000004576 ENSEMBL cdna:SNAP chromosome:CEL140:IV:11769986:11772232:-1 9/11 None
GENEFINDER00000004582 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:11768844:11773606:-1 11/11 None
T12A7.4 ENSEMBL cdna:known chromosome:CEL140:IV:11768617:11773732:-1 gene:T12A7.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:11768849-11773738(-) 100.0 100.0
Public Domain and Genome References
Gene Title lipase
Ensembl T12A7.4
Entrez Gene 188437 Entrez gene
SwissProt Q22420 EMBL-EBI
WormBase CE06436 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
16042 lipid catabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
16298 lipase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA98139 Hypothetical protein T12A7.4 [Caenorhabditis elegans] ref|NP_502230.1| T12A7.4 [Caenorhabditis elegans] 0.0
blast CAE62125 Hypothetical protein CBG06167 [Caenorhabditis briggsae] 0.0
blast CAA98139 Hypothetical protein T12A7.4 [Caenorhabditis elegans] ref|NP_502230.1| T12A7.4 [Caenorhabditis elegans] 1.0E-129
blast CAE62125 Hypothetical protein CBG06167 [Caenorhabditis briggsae] 1.0E-121
blast CAE62401 Hypothetical protein CBG06488 [Caenorhabditis briggsae] 2.0E-89
blast CAE62401 Hypothetical protein CBG06488 [Caenorhabditis briggsae] 3.0E-89
Protein Domains
Database ID Description E-Value
Pfam IPR002918 EMBL-EBI Lipase, class 2 1.0E-126
Pfam IPR002918 EMBL-EBI Lipase, class 2 4.3E-125
Pfam IPR002918 EMBL-EBI Lipase, class 2 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_502230.1 1 34-56
T12A7.4 1 34-56
Sequence
Target Sequence 
>C. ELEGANS:188040_AT
caatgctgacgacggttcatgcaatattgggaaaccattaggaaacaaagtacgtgtaat
tttgggaatcgctggagccaattttggactatgtgcctgcgttggacactggcttggagt
tacgtggccaacatgcaatgatgataatggactgtggcccggagaaacgtgttatccaaa
tccaatgaacggacagtgtgctgcgtcaccattaccctcaccatgcaatggtttgactta
ttccaaatttttaatggatctcaacaactcgcgattcaaaccagcacagcacattttcag
catgtggagtatgggtgacgacttgatcggtgatggaaatatggtttggggtcgtccgac
aagtgagatcccattttc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CAATGCTGACGACGGTTCATGCAAT 551 181 651 Antisense
AATTTTGGACTATGTGCCTGCGTTG 588 175 730 Antisense
TGCCTGCGTTGGACACTGGCTTGGA 342 585 744 Antisense
GGAGTTACGTGGCCAACATGCAATG 479 515 766 Antisense
GACTGTGGCCCGGAGAAACGTGTTA 366 375 800 Antisense
TGAACGGACAGTGTGCTGCGTCACC 574 573 836 Antisense
AATGGATCTCAACAACTCGCGATTC 313 163 903 Antisense
AACTCGCGATTCAAACCAGCACAGC 235 141 916 Antisense
ACCAGCACAGCACATTTTCAGCATG 710 85 930 Antisense
ATATGGTTTGGGGTCGTCCGACAAG 405 17 989 Antisense
GTCCGACAAGTGAGATCCCATTTTC 361 475 1004 Antisense
Sequence Source Affymetrix Proprietary Database