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[187920_at]

Description F46G10.7 /REP_DB=WormBase Gene ID /WP=CE02243 /TR=Q20480 /GB=CAA90546.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=SIR
Cluster 6grp_highest_10_10 > 21      6grp_high1_10_10 > 06      4grp_highest_8_8 > 11      4grp_high_8_8 > 47      6grp_highest_nonorm > 60      6grp_total > 14      4grp_total > 40      6grp_highest_sub > De      6grp_cgc > 30      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 152
1 2 3 4 range
A 388.2
(-3)
P 		392.2
(-2.5)
P 		436.4
(3)
P 		434.2
(2.7)
P 		48
B 325.4
(-3)
P 		440.9
(3)
P 		345
(-2)
P 		375.4
(-0.4)
P 		116
C 343.3
(-2.7)
P 		379
(-1.2)
P 		477.3
(3)
P 		337
(-3)
P 		140
avr 352.3
(-3) 		404
(1.6) 		419.6
(3) 		382.2
(-0.3) 		67

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 497
1 2 3 4 5 6 range
A 711.5
(3)
P 		340.3
(-1.6)
P 		393.2
(-1)
P 		431.4
(-0.5)
P 		303.7
(-2.1)
P 		228.6
(-3)
P 		483
B 488
(3)
P 		472.8
(2.6)
P 		305.2
(-2)
P 		387.3
(0.3)
P 		319.2
(-1.6)
P 		266.7
(-3)
P 		221
C 459.4
(1.8)
P 		521.5
(3)
P 		403.9
(0.7)
P 		303.8
(-1.3)
P 		214.2
(-3)
P 		226.9
(-2.8)
P 		307
avr 553
(3) 		444.9
(0.9) 		367.4
(-0.6) 		374.2
(-0.4) 		279
(-2.3) 		240.7
(-3) 		312
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 110
1 2 3 4 range
A 141.4
(3)
P 		85.1
(-1.3)
P 		114.1
(0.9)
P 		63.6
(-3)
P 		78
B 103.8
(1.9)
P 		108.9
(3)
P 		79.9
(-3)
P 		80
(-3)
P 		29
C 113.6
(0.1)
P 		109
(-0.1)
P 		166.3
(3)
P 		56.8
(-3)
P 		110
avr 119.6
(2.9) 		101
(0.8) 		120.1
(3) 		66.8
(-3) 		53

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 115
1 2 3 4 5 6 range
A 131.2
(3)
P 		121
(2.2)
P 		85.6
(-0.6)
P 		109.4
(1.3)
P 		91.6
(-0.1)
P 		55.7
(-3)
P 		76
B 169.8
(3)
P 		157.4
(2.2)
P 		74.1
(-3)
P 		102.6
(-1.2)
P 		129.7
(0.5)
P 		99.4
(-1.4)
P 		96
C 170.3
(3)
P 		159.1
(2.4)
P 		102.8
(-0.7)
P 		61.1
(-3)
P 		69.3
(-2.5)
P 		76
(-2.2)
P 		109
avr 157.1
(3) 		145.8
(2.2) 		87.5
(-2.2) 		91
(-2) 		96.9
(-1.5) 		77
(-3) 		80
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 187920_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17361
Sequence Type Exemplar sequence
Representative Public ID F46G10.7 NCBI
Target Description F46G10.7 /REP_DB=WormBase Gene ID /WP=CE02243 /TR=Q20480 /GB=CAA90546.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=SIR
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001029501(11), NM_001029502(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001029501 NCBI Caenorhabditis elegans F46G10.7a (SIR) mRNA, complete cds. 11/11 None
NM_001029502 NCBI Caenorhabditis elegans F46G10.7b (SIR) mRNA, complete cds. 11/11 None
SNAP00000042664 ENSEMBL cdna:SNAP chromosome:CEL140:X:13329184:13331022:1 11/11 None
F46G10.7a ENSEMBL cdna:known chromosome:CEL140:X:13329182:13331100:1 gene:F46G10.7 11/11 None
F46G10.7b ENSEMBL cdna:known chromosome:CEL140:X:13329184:13331022:1 gene:F46G10.7 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000042672 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:13329183-13331022(+) 100.0 100.0
Public Domain and Genome References
Ensembl F46G10.7
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAE46663 Hypothetical protein F46G10.7b [Caenorhabditis elegans] ref|NP_001024673.1| F46G10.7b [Caenorhabditis elegans] 1.0E-170
blast CAA90546 Hypothetical protein F46G10.7a [Caenorhabditis elegans] ref|NP_001024672.1| F46G10.7a [Caenorhabditis elegans] 1.0E-169
blast CAE46663 Hypothetical protein F46G10.7b [Caenorhabditis elegans] ref|NP_001024673.1| F46G10.7b [Caenorhabditis elegans] 1.0E-167
blast CAA90546 Hypothetical protein F46G10.7a [Caenorhabditis elegans] ref|NP_001024672.1| F46G10.7a [Caenorhabditis elegans] 1.0E-167
Protein Domains
Database ID Description E-Value
Pfam IPR003000 EMBL-EBI Silent information regulator protein Sir2 8.1E-101
Pfam IPR003000 EMBL-EBI Silent information regulator protein Sir2 2.5E-97
Sequence
Target Sequence 
>C. ELEGANS:187920_AT
tggtctcgcaattttttagcctggccgagatttggtcaagctgctcctaacatcaatcac
tacgcactatcgaaatgggaagcttccgatagattccaatggttaatcacacaaaacgtg
gatgggcttcacttaaaagcgggctcaaaaatggtaacggaacttcatggcagtgctctt
caagtaaaatgtacaacatgtgattacattgaatcaagacaaacgtaccaagaccgactt
gattacgcaaatcctgggtttaaagaagaacacgtggctccaggagagctggcgccagat
ggtgacattattctaccgttgggaactgagaaaggtttccaaattcccgagtgcccaagt
tgtgggggacttatgaagacagatgtcacgttttttggagagaacgttaacatggacaaa
gtcaatttttgttacgagaaagtgaatgaatgtgatgggattttatcacttggcacgtcg
ttggcggtgttatctggatttcggtttatccatcatgctaacatgaagaagaaaccaatt
ttcatagtcaatataggacctacaagagctgatcacatgg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGGTCTCGCAATTTTTTAGCCTGGC 39 547 247 Antisense
TAGCCTGGCCGAGATTTGGTCAAGC 93 627 263 Antisense
TTGGTCAAGCTGCTCCTAACATCAA 325 709 278 Antisense
TAACATCAATCACTACGCACTATCG 466 639 294 Antisense
CACGTGGCTCCAGGAGAGCTGGCGC 210 199 517 Antisense
GAGCTGGCGCCAGATGGTGACATTA 643 385 532 Antisense
AATTCCCGAGTGCCCAAGTTGTGGG 52 175 588 Antisense
GGATTTTATCACTTGGCACGTCGTT 647 509 704 Antisense
ACGTCGTTGGCGGTGTTATCTGGAT 389 95 721 Antisense
GATTTCGGTTTATCCATCATGCTAA 72 427 743 Antisense
GGACCTACAAGAGCTGATCACATGG 518 523 802 Antisense
Sequence Source Affymetrix Proprietary Database