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[187885_at] Isovaleryl-CoA dehydrogenase

Description C02D5.1 /REP_DB=WormBase Gene ID /WP=CE24778 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=Isovaleryl-CoA dehydrogenase
Cluster 6grp_total > 83      4grp_total > 49      6grp_total_sub > Hat      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 300
1 2 3 4 range
A 12.3
(-3)
A 		252.1
(3)
P 		235.2
(2.6)
P 		47.2
(-2.1)
A 		240
B 8
(-3)
A 		232.7
(1.5)
P 		307.7
(3)
P 		8.6
(-3)
A 		300
C 37.9
(-3)
A 		303
(3)
P 		301.5
(3)
P 		40.5
(-2.9)
A 		265
avr 19.4
(-3) 		262.6
(2.6) 		281.5
(3) 		32.1
(-2.7) 		262

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 882
1 2 3 4 5 6 range
A 58.9
(-3)
A 		276.1
(-1.3)
P 		274.6
(-1.3)
P 		586.5
(1.1)
P 		826.8
(3)
P 		202
(-1.9)
P 		768
B 75.3
(-3)
A 		257.5
(-1.7)
P 		240.5
(-1.8)
P 		658.2
(1.1)
P 		931.8
(3)
P 		178.4
(-2.3)
P 		857
C 50.2
(-3)
A 		325.7
(-0.5)
P 		229.5
(-1.4)
P 		520.2
(1.3)
P 		708.6
(3)
P 		190.4
(-1.7)
P 		658
avr 61.5
(-3) 		286.4
(-1.2) 		248.2
(-1.5) 		588.3
(1.2) 		822.4
(3) 		190.3
(-2) 		761
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 103
1 2 3 4 range
A 4.5
(-3)
A 		54.7
(2.3)
P 		61.5
(3)
P 		6.9
(-2.7)
A 		57
B 2.6
(-2.9)
A 		57.5
(1.8)
P 		71.3
(3)
P 		1.8
(-3)
A 		70
C 12.5
(-2.7)
A 		87.1
(1.9)
P 		105.1
(3)
P 		6.8
(-3)
A 		98
avr 6.5
(-2.9) 		66.4
(2) 		79.3
(3) 		5.2
(-3) 		74

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 368
1 2 3 4 5 6 range
A 10.9
(-3)
A 		98.2
(-0.8)
P 		59.8
(-1.8)
P 		148.7
(0.5)
P 		249.5
(3)
P 		49.2
(-2)
P 		239
B 26.2
(-3)
A 		85.7
(-2)
P 		58.4
(-2.5)
P 		174.3
(-0.5)
P 		378.6
(3)
P 		66.5
(-2.3)
P 		352
C 18.6
(-3)
A 		99.4
(-0.7)
P 		58.4
(-1.9)
P 		104.6
(-0.6)
P 		229.3
(3)
P 		63.7
(-1.7)
P 		211
avr 18.6
(-3) 		94.4
(-1.3) 		58.9
(-2.1) 		142.5
(-0.2) 		285.8
(3) 		59.8
(-2.1) 		267
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 187885_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6191
Sequence Type Exemplar sequence
Representative Public ID C02D5.1 NCBI
Target Description C02D5.1 /REP_DB=WormBase Gene ID /WP=CE24778 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=Isovaleryl-CoA dehydrogenase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066484(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066484 NCBI Caenorhabditis elegans C02D5.1 (C02D5.1) mRNA, complete cds. 11/11 None
GENEFINDER00000012230 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:8559645:8562819:1 11/11 None
SNAP00000012228 ENSEMBL cdna:SNAP chromosome:CEL140:III:8561089:8562876:1 11/11 None
C02D5.1 ENSEMBL cdna:known chromosome:CEL140:III:8561089:8562876:1 gene:C02D5.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:8561083-8562871(+) 100.0 100.0
Public Domain and Genome References
Gene Title Isovaleryl-CoA dehydrogenase
Ensembl C02D5.1
Entrez Gene 182112 Entrez gene
SwissProt P34275 EMBL-EBI
WormBase CE24778 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CHICKEN:GGA.2954.1.S1_AT similar to Hypothetical protein zgc:85777 gga
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6118 electron transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3995 acyl-CoA dehydrogenase activity inferred from electronic annotation QuickGO AmiGO
16491 oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA27913 Hypothetical protein C02D5.1 [Caenorhabditis elegans] ref|NP_498885.1| C02D5.1 [Caenorhabditis elegans] sp|P34275|IVD_CAEEL Probable isovaleryl-CoA dehydrogenase (IVD) 0.0
blast CAE71237 Hypothetical protein CBG18107 [Caenorhabditis briggsae] 0.0
blast AAB52448 Hypothetical protein C37A2.3 [Caenorhabditis elegans] ref|NP_491942.1| C37A2.3 [Caenorhabditis elegans] 0.0
Protein Families
Method ID Description E-Value
ec ACDL_HUMAN (P28330) Acyl-CoA dehydrogenase, long-chain specific, mitochondrial precursor (EC 1.3.99.13) (LCAD) 1.0E-128
ec ACDL_HUMAN (P28330) Acyl-CoA dehydrogenase, long-chain specific, mitochondrial precursor (EC 1.3.99.13) (LCAD) 1.0E-130
Protein Domains
Database ID Description E-Value
Pfam IPR006090 EMBL-EBI Acyl-CoA dehydrogenase, C-terminal 1.6E-57
Pfam IPR006091 EMBL-EBI Acyl-CoA dehydrogenase, central domain 7.0E-63
Pfam IPR006092 EMBL-EBI Acyl-CoA dehydrogenase, N-terminal 8.8E-11
Pfam IPR006090 EMBL-EBI Acyl-CoA dehydrogenase, C-terminal 7.7E-53
Pfam IPR006091 EMBL-EBI Acyl-CoA dehydrogenase, central domain 7.0E-63
Pfam IPR006092 EMBL-EBI Acyl-CoA dehydrogenase, N-terminal 8.8E-11
Sequence
Target Sequence 
>C. ELEGANS:187885_AT
gtcgctggtgtgtattccactggactcaattggtgtacatcgatcaactccgttggataa
attaggaatgagaagctccgatacagttcaactattttttgaagatgttagggttccctc
gtcatacataataggcgaagaaggacgtggatttgcatatcaaatgaatcaattcaatga
tgagcgccttgtaacagttgctgttgggcttctcccacttcaaaaatgtataaatgagac
gattgagtatgcaagagaacgattaatatttggaaagacacttctcgatcagcaatatgt
tcaatttcggttagccgagttggaggctgaactggaggcaacccgttctttgctctatcg
aacagtgctggcacgttgccaaggcgaggatgtgagcatgttgactgcgatggcgaaatt
gaaaattggaagactggcaagaaaagttactgatcagtgtctacagatctggggaggtgc
tggatatctgaatgacaatggaatatcgagagccttcagagatttccgtatattttcgat
tggcgct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTCGCTGGTGTGTATTCCACTGGAC 518 475 624 Antisense
TGGTGTACATCGATCAACTCCGTTG 43 553 654 Antisense
GAGAAGCTCCGATACAGTTCAACTA 54 393 693 Antisense
GATGTTAGGGTTCCCTCGTCATACA 412 405 727 Antisense
GAGCGCCTTGTAACAGTTGCTGTTG 372 385 805 Antisense
AAGACACTTCTCGATCAGCAATATG 251 153 898 Antisense
TGGAGGCTGAACTGGAGGCAACCCG 138 547 944 Antisense
ACCCGTTCTTTGCTCTATCGAACAG 628 89 964 Antisense
GTGCTGGCACGTTGCCAAGGCGAGG 385 477 988 Antisense
GAGAGCCTTCAGAGATTTCCGTATA 290 395 1131 Antisense
TTTCCGTATATTTTCGATTGGCGCT 389 669 1146 Antisense
Sequence Source Affymetrix Proprietary Database