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[187876_at] ubiquitin-conjugating enzyme

Description B0403.2 /REP_DB=WormBase Gene ID /WP=CE03882 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=ubiquitin-conjugating enzyme
Cluster 6grp_highest_10_10 > 84      6grp_high1_10_10 > 48      4grp_highest_8_8 > 47      4grp_high_8_8 > 11      6grp_highest_nonorm > 90      6grp_total > 48      4grp_total > 13      6grp_highest_sub > Cu      6grp_cgc > 17      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 259
1 2 3 4 range
A 180.4
(0.8)
P 		94.6
(-2)
P 		65.5
(-3)
P 		246.5
(3)
P 		181
B 214.1
(0.7)
P 		89.3
(-2.5)
P 		69.3
(-3)
P 		304.2
(3)
P 		235
C 188.6
(0.1)
P 		53.7
(-3)
P 		55.4
(-3)
P 		312.6
(3)
P 		259
avr 194.4
(0.5) 		79.2
(-2.6) 		63.4
(-3) 		287.8
(3) 		224

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 111
1 2 3 4 5 6 range
A 128.1
(2.9)
P 		99.3
(-3)
P 		102.6
(-2.3)
P 		105.3
(-1.8)
P 		109.2
(-1)
P 		128.4
(3)
P 		29
B 184.4
(3)
P 		143.2
(0.2)
P 		116.9
(-1.6)
P 		95.9
(-3)
P 		122.2
(-1.2)
P 		166.4
(1.8)
P 		89
C 144.4
(1.1)
P 		114.7
(-0.6)
P 		73
(-3)
P 		129.1
(0.2)
P 		94.5
(-1.8)
P 		177.1
(3)
P 		104
avr 152.3
(2.5) 		119.1
(-0.8) 		97.5
(-3) 		110.1
(-1.7) 		108.6
(-1.9) 		157.3
(3) 		60
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 53
1 2 3 4 range
A 65.7
(3)
P 		20.5
(-2.6)
P 		17.1
(-3)
P 		36.1
(-0.7)
P 		49
B 68.3
(3)
P 		22.1
(-2.3)
P 		16.1
(-3)
P 		64.8
(2.6)
P 		52
C 62.4
(3)
P 		15.4
(-3)
P 		19.3
(-2.5)
P 		52.7
(1.8)
P 		47
avr 65.5
(3) 		19.3
(-2.8) 		17.5
(-3) 		51.2
(1.2) 		48

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 46
1 2 3 4 5 6 range
A 23.6
(-2.4)
P 		35.3
(3)
P 		22.3
(-3)
P 		26.7
(-1)
P 		33
(1.9)
P 		31.3
(1.2)
P 		13
B 64.1
(3)
P 		47.7
(0.5)
P 		28.4
(-2.5)
P 		25.4
(-3)
P 		49.7
(0.8)
P 		62
(2.7)
P 		39
C 53.5
(2.1)
P 		35
(-0.6)
P 		18.6
(-3)
P 		26
(-1.9)
P 		30.6
(-1.2)
P 		59.3
(3)
P 		41
avr 47.1
(2.2) 		39.3
(0.5) 		23.1
(-3) 		26
(-2.4) 		37.8
(0.2) 		50.9
(3) 		28
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 187876_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16618
Sequence Type Exemplar sequence
Representative Public ID B0403.2 NCBI
Target Description B0403.2 /REP_DB=WormBase Gene ID /WP=CE03882 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=ubiquitin-conjugating enzyme
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076787(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_076787 NCBI Caenorhabditis elegans UBiquitin Conjugating enzyme family member (ubc-17) (ubc-17) mRNA, complete cds. 11/11 None
GENEFINDER00000026990 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:7050575:7055321:1 11/11 None
SNAP00000026983 ENSEMBL cdna:SNAP chromosome:CEL140:X:7052959:7055321:1 11/11 None
B0403.2 ENSEMBL cdna:known chromosome:CEL140:X:7050575:7055321:1 gene:B0403.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:7053198-7055320(+) 100.0 100.0
Public Domain and Genome References
Gene Title ubiquitin-conjugating enzyme
Gene Symbol ubc-17
Ensembl B0403.2
Entrez Gene 181979 Entrez gene
SwissProt Q11076 EMBL-EBI
WormBase CE37602 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1604272_AT similar to Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon) cfa
CANINE:1590100_AT similar to Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon) cfa
CANINE:1588860_AT similar to Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon) cfa
CANINE_2:CFA.1008.1.A1_S_AT similar to Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon) cfa
CANINE_2:CFA.19755.1.S1_S_AT similar to Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon) cfa
CANINE_2:CFA.9179.1.A1_AT similar to Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon) cfa
CANINE_2:CFAAFFX.9668.1.S1_AT similar to Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon) cfa
DROSOPHILA_2:1634454_AT dm
DROSGENOME1:149628_AT dm
CHICKEN:GGA.13770.1.S1_S_AT baculoviral IAP repeat-containing 6 (apollon) gga
CHICKEN:GGAAFFX.6664.1.S1_AT baculoviral IAP repeat-containing 6 (apollon) gga
HG-U133_PLUS_2:224635_S_AT baculoviral IAP repeat-containing 6 (apollon) hs
HG-U133B:224635_S_AT baculoviral IAP repeat-containing 6 (apollon) hs
HG-U133_PLUS_2:233093_S_AT baculoviral IAP repeat-containing 6 (apollon) hs
HG-U133B:233093_S_AT baculoviral IAP repeat-containing 6 (apollon) hs
HU35KSUBC:RC_AA479961_AT baculoviral IAP repeat-containing 6 (apollon) hs
HU35KSUBD:RC_N23031_AT baculoviral IAP repeat-containing 6 (apollon) hs
HU35KSUBD:RC_AA609134_AT baculoviral IAP repeat-containing 6 (apollon) hs
U133_X3P:HS.250646.1.S1_3P_A_AT baculoviral IAP repeat-containing 6 (apollon) hs
U133_X3P:HS.250646.0.S2_3P_A_AT baculoviral IAP repeat-containing 6 (apollon) hs
HG-U95B:45215_AT baculoviral IAP repeat-containing 6 (apollon) hs
HG-U95C:65603_AT baculoviral IAP repeat-containing 6 (apollon) hs
HG-U95E:67284_R_AT baculoviral IAP repeat-containing 6 (apollon) hs
HG-U133_PLUS_2:242068_AT Baculoviral IAP repeat-containing 6 (apollon) hs
HG-U133B:242068_AT Baculoviral IAP repeat-containing 6 (apollon) hs
HG-U95B:46558_AT Baculoviral IAP repeat-containing 6 (apollon) hs
HG-U95C:57462_R_AT Baculoviral IAP repeat-containing 6 (apollon) hs
HG-U95B:58806_AT Baculoviral IAP repeat-containing 6 (apollon) hs
HG-U95E:67542_AT Baculoviral IAP repeat-containing 6 (apollon) hs
HG-U95D:69892_R_AT Baculoviral IAP repeat-containing 6 (apollon) hs
HG-U95D:82994_AT Baculoviral IAP repeat-containing 6 (apollon) hs
HG-U95D:84266_AT Baculoviral IAP repeat-containing 6 (apollon) hs
HU35KSUBD:RC_AA608794_AT Baculoviral IAP repeat-containing 6 (apollon) hs
HU35KSUBD:RC_H91679_AT Baculoviral IAP repeat-containing 6 (apollon) hs
U133_X3P:HS.112592.0.A1_3P_AT Baculoviral IAP repeat-containing 6 (apollon) hs
MOUSE430_2:1442959_AT baculoviral IAP repeat-containing 6 mm
MOE430B:1442959_AT baculoviral IAP repeat-containing 6 mm
MOUSE430_2:1427488_A_AT baculoviral IAP repeat-containing 6 mm
MOUSE430A_2:1427488_A_AT baculoviral IAP repeat-containing 6 mm
MOE430A:1427488_A_AT baculoviral IAP repeat-containing 6 mm
MG-U74AV2:102754_AT baculoviral IAP repeat-containing 6 mm
MOE430A:1419563_AT baculoviral IAP repeat-containing 6 mm
MOUSE430A_2:1419563_AT baculoviral IAP repeat-containing 6 mm
MOUSE430_2:1419563_AT baculoviral IAP repeat-containing 6 mm
MOE430A:1419562_AT baculoviral IAP repeat-containing 6 mm
MOUSE430A_2:1419562_AT baculoviral IAP repeat-containing 6 mm
MOUSE430_2:1419562_AT baculoviral IAP repeat-containing 6 mm
MOE430B:1437789_AT baculoviral IAP repeat-containing 6 mm
MOUSE430_2:1437789_AT baculoviral IAP repeat-containing 6 mm
MG-U74BV2:114610_AT Baculoviral IAP repeat-containing 6 (Birc6), mRNA mm
MG-U74CV2:129335_AT Baculoviral IAP repeat-containing 6 (Birc6), mRNA mm
MG-U74CV2:137595_AT Baculoviral IAP repeat-containing 6 (Birc6), mRNA mm
MOE430B:1442495_AT Baculoviral IAP repeat-containing 6 (Birc6), mRNA mm
MOUSE430_2:1442495_AT Baculoviral IAP repeat-containing 6 (Birc6), mRNA mm
MU19KSUBA:TC16441_AT Baculoviral IAP repeat-containing 6 (Birc6), mRNA mm
MU19KSUBC:TC38002_AT Baculoviral IAP repeat-containing 6 (Birc6), mRNA mm
RAE230B:1382236_AT Similar to hypothetical protein FLJ20272 (predicted) rn
RAT230_2:1382236_AT Similar to hypothetical protein FLJ20272 (predicted) rn
RG-U34B:RC_AA963239_AT Similar to hypothetical protein FLJ20272 (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6464 protein modification inferred from electronic annotation QuickGO AmiGO
6512 ubiquitin cycle inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4840 ubiquitin conjugating enzyme activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC47063 Ubiquitin conjugating enzyme protein 17 [Caenorhabditis elegans] ref|NP_509188.2| UBiquitin Conjugating enzyme family member (ubc-17) [Caenorhabditis elegans] sp|Q11076|UBC17_CAEEL Probable ubiquitin-conjugating enzyme protein 0.0
blast CAE65834 Hypothetical protein CBG10959 [Caenorhabditis briggsae] 0.0
blast XP_419512 PREDICTED: similar to baculoviral IAP repeat-containing 6 [Gallus gallus] 9.0E-81
blast EAA08209 ENSANGP00000002826 [Anopheles gambiae str. PEST] ref|XP_312274.2| ENSANGP00000002826 [Anopheles gambiae str. PEST] 3.0E-63
Protein Domains
Database ID Description E-Value
Pfam IPR000608 EMBL-EBI Ubiquitin-conjugating enzymes 1.2E-35
Pfam IPR000608 EMBL-EBI Ubiquitin-conjugating enzymes 1.3E-36
Pfam IPR000608 EMBL-EBI Ubiquitin-conjugating enzymes 2.1E-32
Sequence
Target Sequence 
>C. ELEGANS:187876_AT
tggggacgtgggaagggcgaccagaggaaaaatggaatccatactgctctttgatgcagg
ttttagtaagcattcaggaagttattgagaaacatttgtggctgaaacgggaagcaattc
tgaaacaggctcaagcttggattgacaatgttagtaacgactttggagatgacaagatga
gcaaaagaaaagatgtttttgcatttgaaactggatttaatcctgctactcaggagcgcg
tgattcacaacttgattcaagaattacaagcaatgcagtcaccgtttgcaaaagaagaag
ctgaagaatccgaacggctgaaacgggaacagagtgaaaaagaagaaaaacaaaaaaaag
aagccgctgcgttagctgaaattgaacgagaaaagcgagagcttgaattagattttcaac
gtcggagatccagtgttttagcaactcatgttgcagtgattagaacacaaccaactggtg
attactctgtccc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGGGGACGTGGGAAGGGCGACCAGA 124 553 761 Antisense
TGGAATCCATACTGCTCTTTGATGC 351 547 793 Antisense
GAAACAGGCTCAAGCTTGGATTGAC 13 355 882 Antisense
ACTGGATTTAATCCTGCTACTCAGG 638 93 970 Antisense
GCTACTCAGGAGCGCGTGATTCACA 123 303 985 Antisense
GCGCGTGATTCACAACTTGATTCAA 489 285 996 Antisense
CAAGCAATGCAGTCACCGTTTGCAA 700 185 1027 Antisense
GAAGCCGCTGCGTTAGCTGAAATTG 368 343 1120 Antisense
GATTTTCAACGTCGGAGATCCAGTG 165 429 1171 Antisense
GATCCAGTGTTTTAGCAACTCATGT 501 415 1187 Antisense
AACCAACTGGTGATTACTCTGTCCC 305 135 1229 Antisense
Sequence Source Affymetrix Proprietary Database