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[187874_at] casein kinase

Description B0205.7 /REP_DB=WormBase Gene ID /WP=CE17321 /GB=AAC16993.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=casein kinase
Cluster 6grp_highest_10_10 > 82      6grp_high1_10_10 > 38      4grp_highest_8_8 > 23      4grp_high_8_8 > 06      6grp_highest_nonorm > 57      6grp_total > 18      4grp_total > 02      6grp_highest_sub > Cu      6grp_cgc > 01      6grp_high1_sub > Cu      6grp_total_sub > Decrease      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 8879
1 2 3 4 range
A 3438.6
(-2.5)
P 		2713
(-3)
P 		2945.8
(-2.8)
P 		11401.1
(3)
P 		8688
B 2873
(-2.8)
P 		2522.6
(-3)
P 		2710.1
(-2.9)
P 		11051.4
(3)
P 		8529
C 3467.7
(-2.6)
P 		3147
(-2.9)
P 		2988.6
(-3)
P 		9640.3
(3)
P 		6652
avr 3259.8
(-2.6) 		2794.2
(-3) 		2881.5
(-2.9) 		10697.6
(3) 		7903

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2341
1 2 3 4 5 6 range
A 2872.3
(1.3)
P 		3008.7
(2.1)
P 		2065.8
(-3)
P 		2616.4
(-0.1)
P 		2301.1
(-1.7)
P 		3186
(3)
P 		1120
B 2658.7
(2.3)
P 		2314.9
(-3)
P 		2704.9
(3)
P 		2562.1
(0.8)
P 		2681.5
(2.6)
P 		2393.4
(-1.8)
P 		390
C 4406.9
(3)
P 		2231
(-3)
P 		2541.8
(-2.1)
P 		2766.3
(-1.5)
P 		2765.6
(-1.5)
P 		2617.8
(-1.9)
P 		2176
avr 3312.6
(3) 		2518.2
(-2.4) 		2437.5
(-3) 		2648.3
(-1.6) 		2582.7
(-2) 		2732.4
(-1) 		875
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1766
1 2 3 4 range
A 1252
(0.7)
P 		588.9
(-3)
P 		770.1
(-2)
P 		1668.9
(3)
P 		1080
B 916.2
(-2)
P 		623
(-3)
P 		628
(-3)
P 		2355.1
(3)
P 		1732
C 1147.9
(-1)
P 		904.8
(-3)
P 		1041.6
(-1.9)
P 		1625.5
(3)
P 		721
avr 1105.4
(-1) 		705.6
(-3) 		813.2
(-2.5) 		1883.2
(3) 		1178

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1184
1 2 3 4 5 6 range
A 529.5
(-2.2)
P 		1070
(3)
P 		449.9
(-3)
P 		663.6
(-0.9)
P 		694.4
(-0.6)
P 		775.7
(0.2)
P 		620
B 925.1
(0.7)
P 		770.5
(-1.4)
P 		656.8
(-3)
P 		678.6
(-2.7)
P 		1089.5
(3)
P 		892.5
(0.3)
P 		433
C 1633.5
(3)
P 		680.7
(-2.3)
P 		646.9
(-2.5)
P 		556.3
(-3)
P 		894.9
(-1.1)
P 		876.3
(-1.2)
P 		1077
avr 1029.4
(3) 		840.4
(0.5) 		584.5
(-3) 		632.8
(-2.3) 		892.9
(1.2) 		848.2
(0.6) 		445
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 187874_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1841
Sequence Type Exemplar sequence
Representative Public ID B0205.7 NCBI
Target Description B0205.7 /REP_DB=WormBase Gene ID /WP=CE17321 /GB=AAC16993.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=casein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060410(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060410 NCBI Caenorhabditis elegans protein KINase family member (kin-3) (kin-3) mRNA, complete cds. 11/11 None
SNAP00000024670 ENSEMBL cdna:SNAP chromosome:CEL140:I:10742160:10744361:1 11/11 None
GENEFINDER00000024677 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:10742160:10744361:1 11/11 None
B0205.7.1 ENSEMBL cdna:known chromosome:CEL140:I:10742139:10744730:1 gene:B0205.7 11/11 None
B0205.7.2 ENSEMBL cdna:known chromosome:CEL140:I:10742143:10744730:1 gene:B0205.7 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:10742090-10744292(+) 100.0 100.0
Public Domain and Genome References
Gene Title casein kinase
Gene Symbol kin-3
Ensembl B0205.7
Entrez Gene 172978 Entrez gene
SwissProt P18334 EMBL-EBI
WormBase CE17321 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:16146_AT casein kinase II alpha chain 2 at
ATH1-121501:252192_AT casein kinase II alpha chain 2 at
CANINE:1587516_AT similar to casein kinase II alpha 1 subunit isoform a cfa
CANINE:1585359_AT similar to casein kinase II alpha 1 subunit isoform a cfa
CANINE_2:CFA.10060.1.A1_AT similar to casein kinase II alpha 1 subunit isoform a cfa
CANINE_2:CFAAFFX.11318.1.S1_AT similar to casein kinase II alpha 1 subunit isoform a cfa
CANINE_2:CFAAFFX.11318.1.S1_S_AT similar to casein kinase II alpha 1 subunit isoform a cfa
DROSOPHILA_2:1640051_S_AT Casein kinase II subunit dm
HG-U95AV2:594_S_AT casein kinase 2, alpha 1 polypeptide hs
HC-G110:594_S_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133A:212073_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133A_2:212073_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133_PLUS_2:212073_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133A:212072_S_AT casein kinase 2, alpha 1 polypeptide hs
HG-FOCUS:212072_S_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133A_2:212072_S_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133_PLUS_2:212072_S_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133A:206075_S_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133_PLUS_2:206075_S_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133A_2:206075_S_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133A_2:212075_S_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133_PLUS_2:212075_S_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133A:212075_S_AT casein kinase 2, alpha 1 polypeptide hs
HUGENEFL:M55265_AT casein kinase 2, alpha 1 polypeptide hs
U133_X3P:G4503094_3P_A_AT casein kinase 2, alpha 1 polypeptide hs
U133_X3P:HS.155140.3.S3_3P_AT casein kinase 2, alpha 1 polypeptide hs
U133_X3P:HS.155140.3.S2_3P_AT casein kinase 2, alpha 1 polypeptide hs
U133_X3P:HS.155140.3.S1_3P_A_AT casein kinase 2, alpha 1 polypeptide hs
HG-U95AV2:40258_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133_PLUS_2:229212_AT Casein kinase 2, alpha 1 polypeptide hs
HG-U133B:229212_AT Casein kinase 2, alpha 1 polypeptide hs
HG-U133_PLUS_2:237907_AT Casein kinase 2, alpha 1 polypeptide hs
HG-U133B:237907_AT Casein kinase 2, alpha 1 polypeptide hs
HG-U133_PLUS_2:239228_AT Casein kinase 2, alpha 1 polypeptide hs
HG-U133B:239228_AT Casein kinase 2, alpha 1 polypeptide hs
HG-U95AV2:36235_AT Casein kinase 2, alpha 1 polypeptide hs
HG-U95C:60425_AT Casein kinase 2, alpha 1 polypeptide hs
HG-U95E:74832_AT Casein kinase 2, alpha 1 polypeptide hs
HU35KSUBB:RC_D60799_AT Casein kinase 2, alpha 1 polypeptide hs
U133_X3P:HS.155140.2.A1_3P_AT Casein kinase 2, alpha 1 polypeptide hs
U133_X3P:HS.282945.0.A1_3P_AT Casein kinase 2, alpha 1 polypeptide hs
U133_X3P:HS.292385.0.A1_3P_AT Casein kinase 2, alpha 1 polypeptide hs
MOUSE430_2:1453427_AT casein kinase II, alpha 1 polypeptide mm
MOUSE430A_2:1453427_AT casein kinase II, alpha 1 polypeptide mm
MOE430A:1453427_AT casein kinase II, alpha 1 polypeptide mm
MOE430A:1419038_A_AT casein kinase II, alpha 1 polypeptide mm
MOUSE430A_2:1419038_A_AT casein kinase II, alpha 1 polypeptide mm
MOUSE430_2:1419038_A_AT casein kinase II, alpha 1 polypeptide mm
MU11KSUBA:AA266026_S_AT casein kinase II, alpha 1 polypeptide mm
MU11KSUBA:U51866_S_AT casein kinase II, alpha 1 polypeptide mm
MG-U74AV2:103441_AT casein kinase II, alpha 1 polypeptide mm
MG-U74AV2:104545_AT casein kinase II, alpha 1 polypeptide mm
MG-U74AV2:104546_G_AT casein kinase II, alpha 1 polypeptide mm
MG-U74AV2:160690_AT casein kinase II, alpha 1 polypeptide mm
MOE430A:1419037_AT casein kinase II, alpha 1 polypeptide mm
MOUSE430A_2:1419037_AT casein kinase II, alpha 1 polypeptide mm
MOUSE430_2:1419037_AT casein kinase II, alpha 1 polypeptide mm
MOE430A:1419035_S_AT casein kinase II, alpha 1 polypeptide mm
MOUSE430A_2:1419035_S_AT casein kinase II, alpha 1 polypeptide mm
MOUSE430_2:1419035_S_AT casein kinase II, alpha 1 polypeptide mm
MOE430A:1419034_AT casein kinase II, alpha 1 polypeptide mm
MOUSE430A_2:1419034_AT casein kinase II, alpha 1 polypeptide mm
MOUSE430_2:1419034_AT casein kinase II, alpha 1 polypeptide mm
MOE430A:1419036_AT casein kinase II, alpha 1 polypeptide mm
MOUSE430A_2:1419036_AT casein kinase II, alpha 1 polypeptide mm
MOUSE430_2:1419036_AT casein kinase II, alpha 1 polypeptide mm
MU19KSUBB:TC31462_AT Casein kinase II, alpha 1 polypeptide, mRNA (cDNA clone MGC:13987 IMAGE:4188101) mm
RG-U34A:L15618_AT casein kinase II, alpha 1 polypeptide rn
RG-U34B:RC_AI012245_AT casein kinase II, alpha 1 polypeptide rn
RAE230A:1387170_AT casein kinase II, alpha 1 polypeptide rn
RAT230_2:1387170_AT casein kinase II, alpha 1 polypeptide rn
RAE230B:1392650_AT casein kinase II, alpha 1 polypeptide rn
RAT230_2:1392650_AT casein kinase II, alpha 1 polypeptide rn
RAE230B:1384339_S_AT casein kinase II, alpha 1 polypeptide rn
RAT230_2:1384339_S_AT casein kinase II, alpha 1 polypeptide rn
RAE230A:1375636_AT Casein kinase II, alpha 1 polypeptide rn
RAT230_2:1375636_AT Casein kinase II, alpha 1 polypeptide rn
RAE230A:1376616_AT Casein kinase II, alpha 1 polypeptide rn
RAT230_2:1376616_AT Casein kinase II, alpha 1 polypeptide rn
RAE230A:1389974_AT Casein kinase II, alpha 1 polypeptide rn
RAT230_2:1389974_AT Casein kinase II, alpha 1 polypeptide rn
RG-U34A:RC_AA800210_AT Casein kinase II, alpha 1 polypeptide rn
RG-U34A:RC_AA875506_AT Casein kinase II, alpha 1 polypeptide rn
RG-U34B:RC_AA899254_AT Casein kinase II, alpha 1 polypeptide rn
RG-U34C:RC_AI179620_AT Casein kinase II, alpha 1 polypeptide rn
RG-U34A:RC_AI072089_AT Casein kinase II, alpha 1 polypeptide rn
YEAST_2:1771598_AT Alpha' catalytic subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKB1 and CKB2, the many substrates include transcription factors and all RNA polymerases Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC16993 Protein kinase protein 3 [Caenorhabditis elegans] ref|NP_492811.1| protein KINase family member (kin-3) [Caenorhabditis elegans] sp|P18334|CSK2A_CAEEL Casein kinase II, alpha chain (CK II alpha subunit) gb|AAA27984.1| casein kinase II-alpha 0.0
blast CAE67357 Hypothetical protein CBG12820 [Caenorhabditis briggsae] 1.0E-179
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-23
hanks 3.1.3 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; Cdk3 6.0E-30
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.7E-79
Sequence
Target Sequence 
>C. ELEGANS:187874_AT
ggactataatgttcgtgttgcttctagatatttcaagggacccgagcttcttgtcgatta
tcaatgttacgattattcgttggatatgtggagtttgggatgcatgttggctagtatgat
cttcaggaaggaaccattcttccacggccatgataactacgatcagctagtccgcattgc
aaaggtattgggaactgatgagctttacgagtacattgcgagatatcacattgatctcga
tccacgcttcaacgatattctcgggcgacactcaagaaaacgctgggaaagatttatcca
cgctgaaaatcaacatcttgtcaccccagaggctcttgatttccttgataaacttcttcg
ctacgatcacgcggaacgcctaactgctcaagaggccatgggtcacgaatacttccgccc
agttgttgaagcacatgc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGACTATAATGTTCGTGTTGCTTCT 284 525 567 Antisense
ACCCGAGCTTCTTGTCGATTATCAA 191 89 606 Antisense
ATTCTTCCACGGCCATGATAACTAC 568 11 702 Antisense
TACGATCAGCTAGTCCGCATTGCAA 590 647 724 Antisense
ATCACATTGATCTCGATCCACGCTT 621 27 791 Antisense
GATCCACGCTTCAACGATATTCTCG 343 415 805 Antisense
CCCCAGAGGCTCTTGATTTCCTTGA 194 261 890 Antisense
ACTTCTTCGCTACGATCACGCGGAA 516 103 918 Antisense
ACTGCTCAAGAGGCCATGGGTCACG 705 97 949 Antisense
CATGGGTCACGAATACTTCCGCCCA 215 209 963 Antisense
TCCGCCCAGTTGTTGAAGCACATGC 75 597 980 Antisense
Sequence Source Affymetrix Proprietary Database