[Home] | [Total List]

[187866_at] potassium channel

Description M02A10.2 /REP_DB=WormBase Gene ID /WP=CE07387 /GEN=irk-2 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=potassium channel
Cluster 6grp_total > 09      4grp_total > 20      6grp_cgc > 0      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 179
1 2 3 4 range
A 114.9
(0.3)
P 		71.3
(-1.2)
A 		16.5
(-3)
A 		195.3
(3)
P 		179
B 108
(1.1)
A 		39.4
(-2.6)
A 		32.8
(-3)
A 		142.7
(3)
P 		110
C 49.7
(-2.1)
A 		95.2
(-0.4)
A 		24.3
(-3)
A 		185.7
(3)
P 		161
avr 90.9
(-0.3) 		68.6
(-1.2) 		24.5
(-3) 		174.6
(3) 		150

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 127
1 2 3 4 5 6 range
A 177.2
(3)
P 		102.1
(-1.8)
A 		99.2
(-2)
A 		91.9
(-2.4)
A 		82.7
(-3)
P 		122.6
(-0.5)
P 		95
B 115
(3)
P 		50
(-3)
A 		62.9
(-1.8)
A 		75.1
(-0.7)
A 		105.6
(2.1)
P 		59.6
(-2.1)
M 		65
C 96
(-1)
A 		105.9
(-0)
A 		83.9
(-2.1)
A 		138.6
(3)
M 		73.9
(-3)
A 		100.6
(-0.5)
A 		65
avr 129.4
(3) 		86
(-2.5) 		82
(-3) 		101.9
(-0.5) 		87.4
(-2.3) 		94.3
(-1.4) 		47
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 38
1 2 3 4 range
A 41.8
(3)
P 		15.5
(-1.2)
A 		4.3
(-3)
A 		28.6
(0.9)
P 		38
B 34.5
(3)
A 		9.7
(-2.5)
A 		7.6
(-3)
A 		30.4
(2.1)
P 		27
C 16.4
(-0.9)
A 		27.4
(2)
A 		8.5
(-3)
A 		31.3
(3)
P 		23
avr 30.9
(3) 		17.5
(-0.3) 		6.8
(-3) 		30.1
(2.8) 		24

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 28
1 2 3 4 5 6 range
A 32.7
(1.5)
P 		36.3
(3)
A 		21.6
(-3)
A 		23.3
(-2.3)
A 		25
(-1.6)
P 		29.8
(0.3)
P 		15
B 40
(2.4)
P 		16.6
(-2.7)
A 		15.3
(-3)
A 		19.9
(-2)
A 		42.9
(3)
P 		22.2
(-1.5)
M 		28
C 35.6
(3)
A 		32.3
(1.6)
A 		21.4
(-3)
A 		27.9
(-0.3)
M 		23.9
(-1.9)
A 		33.7
(2.2)
A 		14
avr 36.1
(3) 		28.4
(0.2) 		19.4
(-3) 		23.7
(-1.5) 		30.6
(1) 		28.6
(0.3) 		17
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 187866_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18275
Sequence Type Exemplar sequence
Representative Public ID M02A10.2 NCBI
Target Description M02A10.2 /REP_DB=WormBase Gene ID /WP=CE07387 /GEN=irk-2 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=potassium channel
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_075742(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_075742 NCBI Caenorhabditis elegans Inward Rectifying K (potassium) channel family member (irk-2) (irk-2) mRNA, complete cds. 11/11 None
GENEFINDER00000002292 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:703844:706700:-1 11/11 None
M02A10.2 ENSEMBL cdna:known chromosome:CEL140:X:703248:710151:-1 gene:M02A10.2 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000002287 5/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:703843-710151(-) 100.0 100.0
Public Domain and Genome References
Gene Title potassium channel
Gene Symbol irk-2
Ensembl M02A10.2
Entrez Gene 191695 Entrez gene
SwissProt Q21458 EMBL-EBI
WormBase CE07387 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.16030.1.S1_AT similar to G protein-activated inward rectifier potassium channel 4 (GIRK4) (Potassium channel, inwardly rectifying, subfamily J, member 5) (Inward rectifier K(+) channel Kir3.4) (Heart KATP channel) (KATP-1) (Cardiac inward rectifier) (CIR)... cfa
DROSOPHILA_2:1627795_AT Inwardly rectifying potassium channel dm
DROSGENOME1:150431_AT Inwardly rectifying potassium channel dm
CHICKEN:GGA.546.1.S1_S_AT potassium inwardly-rectifying channel, subfamily J, member 5 gga
CHICKEN:GGAAFFX.23423.1.S1_AT potassium inwardly-rectifying channel, subfamily J, member 5 gga
CHICKEN:GGAAFFX.23423.2.S1_S_AT potassium inwardly-rectifying channel, subfamily J, member 5 gga
CHICKEN:GGA.546.1.S1_AT potassium inwardly-rectifying channel, subfamily J, member 5 gga
HG-U133_PLUS_2:208404_X_AT potassium inwardly-rectifying channel, subfamily J, member 5 hs
HG-U133A:208404_X_AT potassium inwardly-rectifying channel, subfamily J, member 5 hs
HG-U133A_2:208404_X_AT potassium inwardly-rectifying channel, subfamily J, member 5 hs
HG-U133_PLUS_2:208397_X_AT potassium inwardly-rectifying channel, subfamily J, member 5 hs
HG-U133A:208397_X_AT potassium inwardly-rectifying channel, subfamily J, member 5 hs
HG-U133A_2:208397_X_AT potassium inwardly-rectifying channel, subfamily J, member 5 hs
HG-U133_PLUS_2:211304_X_AT potassium inwardly-rectifying channel, subfamily J, member 5 hs
HG-U133A:211304_X_AT potassium inwardly-rectifying channel, subfamily J, member 5 hs
HG-U133A_2:211304_X_AT potassium inwardly-rectifying channel, subfamily J, member 5 hs
HG-U133_PLUS_2:211817_S_AT potassium inwardly-rectifying channel, subfamily J, member 5 hs
HG-FOCUS:211817_S_AT potassium inwardly-rectifying channel, subfamily J, member 5 hs
HG-U133A:211817_S_AT potassium inwardly-rectifying channel, subfamily J, member 5 hs
HG-U133A_2:211817_S_AT potassium inwardly-rectifying channel, subfamily J, member 5 hs
HU35KSUBA:HUM_ALU_AT potassium inwardly-rectifying channel, subfamily J, member 5 hs
HU35KSUBB:HUM_ALU_AT potassium inwardly-rectifying channel, subfamily J, member 5 hs
HU35KSUBC:HUM_ALU_AT potassium inwardly-rectifying channel, subfamily J, member 5 hs
HU35KSUBD:HUM_ALU_AT potassium inwardly-rectifying channel, subfamily J, member 5 hs
HUGENEFL:HUM_ALU_AT potassium inwardly-rectifying channel, subfamily J, member 5 hs
HC-G110:HUM_ALU_AT potassium inwardly-rectifying channel, subfamily J, member 5 hs
HUGENEFL:U52154_AT potassium inwardly-rectifying channel, subfamily J, member 5 hs
U133_X3P:G4826799_3P_X_AT potassium inwardly-rectifying channel, subfamily J, member 5 hs
U133_X3P:G1890045_3P_X_AT potassium inwardly-rectifying channel, subfamily J, member 5 hs
U133_X3P:G1326052_3P_A_AT potassium inwardly-rectifying channel, subfamily J, member 5 hs
HG-U95AV2:32356_AT potassium inwardly-rectifying channel, subfamily J, member 5 hs
U133_X3P:HS2.382929.1.S1_3P_AT Potassium inwardly-rectifying channel, subfamily J, member 5 hs
HG-U133_PLUS_2:1570531_AT Potassium inwardly-rectifying channel, subfamily J, member 5 hs
MG-U74AV2:99376_AT potassium inwardly-rectifying channel, subfamily J, member 5 mm
MU11KSUBB:MSA.2733.0_S_AT potassium inwardly-rectifying channel, subfamily J, member 5 mm
MOE430A:1421762_AT potassium inwardly-rectifying channel, subfamily J, member 5 mm
MOUSE430A_2:1421762_AT potassium inwardly-rectifying channel, subfamily J, member 5 mm
MOUSE430_2:1421762_AT potassium inwardly-rectifying channel, subfamily J, member 5 mm
MOE430B:1441590_AT Potassium inwardly-rectifying channel, subfamily J, member 5 (Kcnj5), mRNA mm
MOUSE430_2:1441590_AT Potassium inwardly-rectifying channel, subfamily J, member 5 (Kcnj5), mRNA mm
RN-U34:L35771_AT potassium inwardly-rectifying channel, subfamily J, member 5 rn
RG-U34A:L35771_AT potassium inwardly-rectifying channel, subfamily J, member 5 rn
RAE230A:1387248_AT potassium inwardly-rectifying channel, subfamily J, member 5 rn
RAT230_2:1387248_AT potassium inwardly-rectifying channel, subfamily J, member 5 rn
RAE230A:1368560_AT potassium inwardly-rectifying channel, subfamily J, member 5 rn
RAT230_2:1368560_AT potassium inwardly-rectifying channel, subfamily J, member 5 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6813 potassium ion transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5242 inward rectifier potassium channel activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC48058 Inward rectifying k (potassium) channel family protein 2 [Caenorhabditis elegans] ref|NP_508143.1| Inward Rectifying K (potassium) channel family member (irk-2) [Caenorhabditis elegans] 0.0
blast CAE63630 Hypothetical protein CBG08126 [Caenorhabditis briggsae] 0.0
blast AAC48058 Inward rectifying k (potassium) channel family protein 2 [Caenorhabditis elegans] ref|NP_508143.1| Inward Rectifying K (potassium) channel family member (irk-2) [Caenorhabditis elegans] 1.0E-142
blast CAE63630 Hypothetical protein CBG08126 [Caenorhabditis briggsae] 1.0E-138
blast XP_392010 PREDICTED: similar to CG6747-PA [Apis mellifera] 1.0E-108
blast XP_392010 PREDICTED: similar to CG6747-PA [Apis mellifera] 5.0E-42
Protein Domains
Database ID Description E-Value
Pfam IPR001838 EMBL-EBI K+ channel, inward rectifier 1.0E-126
Pfam IPR001838 EMBL-EBI K+ channel, inward rectifier 4.2E-101
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_508143.1 1 121-143
M02A10.2 1 121-143
Sequence
Target Sequence 
>C. ELEGANS:187866_AT
gagcccgctttgggagattggagcagatgatttaaaaagcgcaaaatttgagattattgc
aattttggaaggagtggtggaaagcgtcggttcaactacccaagcacggacaagctacct
tccgtcggaaatattatgggggcacaggtttgaaaaactggtgcactacaagaaggaaaa
tggccagtataacattgactttggcaaatttcacaacgtgtactctgtaaataccccgac
atgctcagcagcggaaattgaaaggcttaggtcagaagggatattcaacgagtcggagta
ccaaatgtacccaccgtcagacaataagctcaatcttcttgataatgatgaaatgtcacc
ggttcgcgactcgatagatctcaatcaggtaccacagatacaaattttgcgaagagacag
tgatgaagaccctgatgctggagaggaaagtatggaattggttgaccttggaattcacca
caagtgctcaattcgctctcaatctcccatcatcaactcgacctctcaccttcttcagcc
aatgcacaaga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAGCCCGCTTTGGGAGATTGGAGCA 266 385 954 Antisense
TGGAAAGCGTCGGTTCAACTACCCA 345 545 1031 Antisense
AAGCACGGACAAGCTACCTTCCGTC 184 151 1055 Antisense
GTGTACTCTGTAAATACCCCGACAT 523 485 1171 Antisense
CCCCGACATGCTCAGCAGCGGAAAT 601 261 1187 Antisense
GTCGGAGTACCAAATGTACCCACCG 125 473 1245 Antisense
GTACCCACCGTCAGACAATAAGCTC 656 457 1260 Antisense
GATGAAATGTCACCGGTTCGCGACT 318 411 1300 Antisense
GTTCGCGACTCGATAGATCTCAATC 247 441 1315 Antisense
TCACCACAAGTGCTCAATTCGCTCT 528 625 1428 Antisense
CACCTTCTTCAGCCAATGCACAAGA 598 201 1480 Antisense
Sequence Source Affymetrix Proprietary Database