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[187805_at] dehydrogenase

Description F49E10.6 /REP_DB=WormBase Gene ID /WP=CE07267 /CHR=X /FEA=Sanger Annotation /DEF=(ST.LOUIS) TR:Q20595 protein_id:AAC69110.1
Cluster 6grp_total > 19      4grp_total > 37      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 103
1 2 3 4 range
A 107.3
(3)
A 		41.7
(-1.3)
A 		76.9
(1)
A 		14.9
(-3)
A 		92
B 85.1
(3)
A 		85.4
(3)
A 		10.8
(-3)
A 		27.6
(-1.6)
A 		75
C 77
(0.8)
A 		74.8
(0.6)
A 		14.1
(-3)
A 		114.1
(3)
A 		100
avr 89.8
(3) 		67.3
(0.6) 		33.9
(-3) 		52.2
(-1) 		56

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 69
1 2 3 4 5 6 range
A 7.6
(-3)
A 		11.1
(-2.3)
A 		14
(-1.8)
A 		30.9
(1.5)
A 		38.8
(3)
A 		14.8
(-1.6)
A 		31
B 64.1
(3)
A 		43
(0.8)
A 		47.2
(1.3)
A 		29.2
(-0.6)
A 		52.3
(1.8)
A 		5.9
(-3)
A 		58
C 74.5
(3)
A 		60.2
(1.4)
A 		19.9
(-3)
A 		38.9
(-0.9)
A 		36.8
(-1.1)
A 		33.5
(-1.5)
A 		55
avr 48.7
(3) 		38.1
(0.9) 		27
(-1.3) 		33
(-0.1) 		42.6
(1.8) 		18.1
(-3) 		31
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 37
1 2 3 4 range
A 39.1
(3)
A 		9.1
(-1.9)
A 		20.1
(-0.1)
A 		2.2
(-3)
A 		37
B 27.2
(3)
A 		21.1
(1.5)
A 		2.5
(-3)
A 		5.9
(-2.2)
A 		25
C 25.5
(3)
A 		21.5
(1.8)
A 		4.9
(-3)
A 		19.2
(1.2)
A 		21
avr 30.6
(3) 		17.2
(-0.7) 		9.2
(-3) 		9.1
(-3) 		22

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 26
1 2 3 4 5 6 range
A 1.4
(-3)
A 		3.9
(-1.5)
A 		3.1
(-2)
A 		7.8
(0.7)
A 		11.7
(3)
A 		3.6
(-1.7)
A 		10
B 22.3
(3)
A 		14.3
(0.6)
A 		11.5
(-0.2)
A 		7.7
(-1.4)
A 		21.2
(2.7)
A 		2.2
(-3)
A 		20
C 27.6
(3)
A 		18.4
(0.5)
A 		5.1
(-3)
A 		7.8
(-2.3)
A 		11.9
(-1.2)
A 		11.2
(-1.4)
A 		23
avr 17.1
(3) 		12.2
(0.4) 		6.6
(-2.5) 		7.8
(-1.9) 		14.9
(1.8) 		5.7
(-3) 		11
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 187805_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17279
Sequence Type Exemplar sequence
Representative Public ID F49E10.6 NCBI
Target Description F49E10.6 /REP_DB=WormBase Gene ID /WP=CE07267 /CHR=X /FEA=Sanger Annotation /DEF=(ST.LOUIS) TR:Q20595 protein_id:AAC69110.1
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076582(10)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_076582 NCBI Caenorhabditis elegans F49E10.5 (dehydrogenase) mRNA, complete cds. 10/11 A 
SNAP00000004443 ENSEMBL cdna:SNAP chromosome:CEL140:X:5862715:5863365:1 10/11 None
GENEFINDER00000004450 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:5862715:5863955:1 11/11 None
F49E10.5 ENSEMBL cdna:known chromosome:CEL140:X:5862715:5873278:1 gene:F49E10.5 10/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:5862714-5863955(+) 100.0 100.0
Public Domain and Genome References
Gene Title dehydrogenase
Ensembl F49E10.5
Entrez Gene 180853 Entrez gene
SwissProt Q20595 EMBL-EBI
WormBase CE29966 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:259438_AT C-terminal binding protein (ANGUSTIFOLIA) at
ATGENOME1:20504_AT C-terminal binding protein (ANGUSTIFOLIA) at
CANINE_2:CFAAFFX.25521.1.S1_AT similar to C-terminal binding protein 1 (CtBP1) (C-terminal binding protein 3) (CtBP3) (50 kDa BFA-dependent ADP-ribosylation substrate) (BARS-50) cfa
CANINE_2:CFAAFFX.25525.1.S1_S_AT similar to C-terminal binding protein 1 (CtBP1) (C-terminal binding protein 3) (CtBP3) (50 kDa BFA-dependent ADP-ribosylation substrate) (BARS-50) cfa
DROSOPHILA_2:1623869_AT C-terminal Binding Protein dm
DROSOPHILA_2:1623106_S_AT C-terminal Binding Protein dm
DROSGENOME1:152826_AT C-terminal Binding Protein dm
CHICKEN:GGA.3495.1.S1_S_AT C-terminal binding protein 1 gga
CHICKEN:GGAAFFX.12741.1.S1_AT C-terminal binding protein 1 gga
HG-U133A_2:203392_S_AT C-terminal binding protein 1 hs
HG-U133A:203392_S_AT C-terminal binding protein 1 hs
HG-U133_PLUS_2:203392_S_AT C-terminal binding protein 1 hs
HG-FOCUS:203392_S_AT C-terminal binding protein 1 hs
HU35KSUBA:RC_AA258801_I_AT C-terminal binding protein 1 hs
HU35KSUBA:RC_AA258801_S_AT C-terminal binding protein 1 hs
HU35KSUBA:U37408_AT C-terminal binding protein 1 hs
HUGENEFL:U37408_AT C-terminal binding protein 1 hs
U133_X3P:G4557496_3P_A_AT C-terminal binding protein 1 hs
U133_X3P:HS2.431402.1.S1_3P_AT C-terminal binding protein 1 hs
U133_X3P:HS.239737.2.A1_3P_X_AT C-terminal binding protein 1 hs
U133_X3P:HS.239737.2.A1_3P_A_AT C-terminal binding protein 1 hs
HG-U133_PLUS_2:1557714_AT C-terminal binding protein 1 hs
HG-U133A_2:212863_X_AT C-terminal binding protein 1 hs
HG-U133_PLUS_2:212863_X_AT C-terminal binding protein 1 hs
HG-U133A:212863_X_AT C-terminal binding protein 1 hs
HG-U133A_2:213980_S_AT C-terminal binding protein 1 hs
HG-U133_PLUS_2:213980_S_AT C-terminal binding protein 1 hs
HG-U133A:213980_S_AT C-terminal binding protein 1 hs
HG-U95AV2:41308_AT C-terminal binding protein 1 hs
HG-U95AV2:41309_G_AT C-terminal binding protein 1 hs
HG-U95B:43382_S_AT C-terminal binding protein 1 hs
HG-U95C:55310_AT C-terminal binding protein 1 hs
HG-U133A_2:213979_S_AT Hypothetical protein LOC285463 hs
HG-U133_PLUS_2:213979_S_AT Hypothetical protein LOC285463 hs
HG-U133A:213979_S_AT Hypothetical protein LOC285463 hs
HG-U133_PLUS_2:243180_AT Hypothetical protein LOC285463 hs
HG-U133B:243180_AT Hypothetical protein LOC285463 hs
HG-U95C:61328_AT Hypothetical protein LOC285463 hs
HG-U95C:61329_G_AT Hypothetical protein LOC285463 hs
HG-U95D:70136_R_AT Hypothetical protein LOC285463 hs
HU35KSUBD:RC_R87296_AT Hypothetical protein LOC285463 hs
U133_X3P:HS.239737.1.A1_3P_AT Hypothetical protein LOC285463 hs
U133_X3P:HS.252854.0.A1_3P_AT Hypothetical protein LOC285463 hs
MOUSE430_2:1415702_A_AT C-terminal binding protein 1 mm
MOE430B:1415702_A_AT C-terminal binding protein 1 mm
MOE430A:1415702_A_AT C-terminal binding protein 1 mm
MOUSE430A_2:1415702_A_AT C-terminal binding protein 1 mm
MG-U74AV2:101081_AT C-terminal binding protein 1 mm
MU11KSUBA:AA271294_S_AT C-terminal binding protein 1 mm
MU19KSUBB:TC29839_AT C-terminal binding protein 1, mRNA (cDNA clone MGC:6995 IMAGE:3155102) mm
RG-U34A:AF067795_AT C-terminal binding protein 1 rn
RG-U34A:AF067795_G_AT C-terminal binding protein 1 rn
RAE230A:1370029_AT C-terminal binding protein 1 rn
RAT230_2:1370029_AT C-terminal binding protein 1 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6564 L-serine biosynthesis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3676 nucleic acid binding inferred from electronic annotation QuickGO AmiGO
16616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC69110 Hypothetical protein F49E10.5 [Caenorhabditis elegans] ref|NP_508983.2| F49E10.5 [Caenorhabditis elegans] 0.0
blast CAE68813 Hypothetical protein CBG14767 [Caenorhabditis briggsae] 0.0
blast T34290 hypothetical protein F49E10.5 - Caenorhabditis elegans 0.0
blast AAC69110 Hypothetical protein F49E10.5 [Caenorhabditis elegans] ref|NP_508983.2| F49E10.5 [Caenorhabditis elegans] 2.0E-63
blast AAC69110 Hypothetical protein F49E10.5 [Caenorhabditis elegans] ref|NP_508983.2| F49E10.5 [Caenorhabditis elegans] 1.0E-62
blast CAE68813 Hypothetical protein CBG14767 [Caenorhabditis briggsae] 5.0E-62
blast CAE68813 Hypothetical protein CBG14767 [Caenorhabditis briggsae] 2.0E-61
Protein Domains
Database ID Description E-Value
Pfam IPR006612 EMBL-EBI Zinc-finger protein of unknown function DM3 2.5E-16
Pfam IPR006140 EMBL-EBI D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 1.3E-54
Pfam IPR006139 EMBL-EBI D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2.1E-20
Sequence
Target Sequence 
>C. ELEGANS:187805_AT
gacgacttgtggatttccgaactgcaaatttcgctctcggtatcgtggtcttgaagacaa
tcgccatttctatcgaatcccaaaaagaccgcttattttacgacagaggtggctcaccgc
aattggaagaactgaagagacggttgtttcacagcttcgaatttgctcggctcactttga
aggaggcgagaagaaagaaggagatattccagttcctgatccgacggtggataagcagat
caagattgagctgcctccaaaagaaagtaagaacagtgatcgacgaaggaagcaaaacat
tccggctagatttcctagaccagagtcgccgtcaga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GACGACTTGTGGATTTCCGAACTGC 525 379 18 Antisense
AACTGCAAATTTCGCTCTCGGTATC 582 141 37 Antisense
CGCTCTCGGTATCGTGGTCTTGAAG 553 253 49 Antisense
AATCGCCATTTCTATCGAATCCCAA 108 169 76 Antisense
AAGACCGCTTATTTTACGACAGAGG 340 153 102 Antisense
GGTGGCTCACCGCAATTGGAAGAAC 416 499 125 Antisense
AGAGACGGTTGTTTCACAGCTTCGA 71 69 153 Antisense
TTCGAATTTGCTCGGCTCACTTTGA 707 691 173 Antisense
GAGATATTCCAGTTCCTGATCCGAC 434 397 218 Antisense
GCAAAACATTCCGGCTAGATTTCCT 38 319 309 Antisense
TTCCTAGACCAGAGTCGCCGTCAGA 662 693 329 Antisense
Sequence Source Affymetrix Proprietary Database