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[187759_s_at]

Description Y43C5B.1 /REP_DB=WormBase Gene ID /WP=CE19156 /CHR=4 /FEA=Sanger Annotation /DEF=(HINXTON) TR:Q9XXE4 protein_id:CAA19512.1
Cluster 6grp_highest_10_10 > 40      6grp_high1_10_10 > 16      4grp_highest_8_8 > 50      4grp_high_8_8 > 41      6grp_highest_nonorm > 40      6grp_total > 15      4grp_total > 46      6grp_highest_sub > De      6grp_cgc > 22      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 591
1 2 3 4 range
A 926.5
(3)
P 		513.6
(-1.5)
P 		378
(-3)
P 		438.9
(-2.3)
P 		549
B 818.7
(3)
P 		553
(-0.3)
P 		471.6
(-1.3)
P 		336
(-3)
P 		483
C 914.4
(3)
P 		551.8
(-1.2)
P 		521
(-1.6)
P 		397.5
(-3)
P 		517
avr 886.5
(3) 		539.5
(-1.2) 		456.9
(-2.2) 		390.8
(-3) 		496

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 872
1 2 3 4 5 6 range
A 635.7
(1.4)
P 		728.6
(3)
P 		489.1
(-1.1)
P 		374
(-3)
P 		450.6
(-1.7)
P 		468.2
(-1.4)
P 		355
B 777.6
(3)
P 		713.9
(2)
P 		589.5
(-0)
P 		472.4
(-1.9)
P 		478
(-1.8)
P 		402.5
(-3)
P 		375
C 1211.7
(3)
P 		696.3
(-0.5)
P 		549.9
(-1.6)
P 		340.8
(-3)
P 		479.7
(-2)
P 		339.3
(-3)
P 		872
avr 875
(3) 		712.9
(1) 		542.8
(-1.2) 		395.7
(-3) 		469.4
(-2.1) 		403.3
(-2.9) 		479
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 273
1 2 3 4 range
A 337.4
(3)
P 		111.5
(-2)
P 		98.8
(-2.2)
P 		64.2
(-3)
P 		273
B 261.1
(3)
P 		136.6
(-0.9)
P 		109.3
(-1.8)
P 		71.6
(-3)
P 		190
C 302.7
(3)
P 		158.6
(-0.7)
P 		181.6
(-0.1)
P 		67
(-3)
P 		236
avr 300.4
(3) 		135.6
(-1.2) 		129.9
(-1.4) 		67.6
(-3) 		233

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 381
1 2 3 4 5 6 range
A 117.2
(-2.2)
P 		259.1
(3)
P 		106.5
(-2.6)
P 		94.9
(-3)
P 		136
(-1.5)
P 		114
(-2.3)
P 		164
B 270.6
(3)
P 		237.6
(1.6)
P 		143.1
(-2.3)
P 		125.1
(-3)
P 		194.2
(-0.2)
P 		150.1
(-2)
P 		146
C 449.1
(3)
P 		212.5
(-0.7)
P 		140
(-1.9)
P 		68.5
(-3)
P 		155.2
(-1.6)
P 		113.6
(-2.3)
P 		381
avr 279
(3) 		236.4
(1.6) 		129.9
(-1.9) 		96.2
(-3) 		161.8
(-0.8) 		125.9
(-2) 		183
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 187759_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9383
Sequence Type Exemplar sequence
Representative Public ID Y43C5B.1 NCBI
Target Description Y43C5B.1 /REP_DB=WormBase Gene ID /WP=CE19156 /CHR=4 /FEA=Sanger Annotation /DEF=(HINXTON) TR:Q9XXE4 protein_id:CAA19512.1
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001028125(11), NM_001028123(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001028125 NCBI Caenorhabditis elegans UNCoordinated family member (unc-43) (unc-43) mRNA, complete cds. 11/11 None
NM_001028123 NCBI Caenorhabditis elegans UNCoordinated family member (unc-43) (unc-43) mRNA, complete cds. 11/11 None
K11E8.1d ENSEMBL cdna:known chromosome:CEL140:IV:10324241:10340517:-1 gene:K11E8.1 11/11 A 
K11E8.1l ENSEMBL cdna:known chromosome:CEL140:IV:10324241:10340528:-1 gene:K11E8.1 11/11 A 
K11E8.1b.2 ENSEMBL cdna:known chromosome:CEL140:IV:10338670:10340528:-1 gene:K11E8.1 11/11 A 
K11E8.1b.1 ENSEMBL cdna:known chromosome:CEL140:IV:10338670:10340529:-1 gene:K11E8.1 11/11 A 
K11E8.1b.3 ENSEMBL cdna:known chromosome:CEL140:IV:10338670:10348943:-1 gene:K11E8.1 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000005324 8/11 Cross Hyb Matching Probes None
GENEFINDER00000005327 8/11 Cross Hyb Matching Probes None
Splice Variants
Entrez Total Refseq Isoforms Total Detected By This Probeset Refseq Probesets
177921 12 2 NM_001028122 172058_x_at (11), 175821_s_at (11), 193459_s_at (11), 193463_s_at (11)
NM_001028123 187759_s_at (11), 193459_s_at (11)
NM_001028124 172058_x_at (9), 175820_s_at (11), 175821_s_at (11), 193459_s_at (11), 193463_s_at (11)
NM_001028125 172058_x_at (11), 175821_s_at (11), 175824_s_at (11), 187759_s_at (11), 193459_s_at (11)
NM_001028126 172058_x_at (11), 175820_s_at (11), 175821_s_at (11), 193459_s_at (11)
NM_001028127 172058_x_at (11), 175821_s_at (11), 193459_s_at (11), 193463_s_at (11)
NM_001028128 172058_x_at (11), 175821_s_at (11), 193459_s_at (11), 193463_s_at (11)
NM_001028129 172058_x_at (11), 175820_s_at (11), 175821_s_at (11), 193459_s_at (11), 193463_s_at (11)
NM_001028130 172058_x_at (11), 173423_at (11), 193459_s_at (11)
NM_001028131 175821_s_at (11), 175824_s_at (11), 193459_s_at (11), 193463_s_at (11)
NM_001028132 172058_x_at (9), 175821_s_at (11), 175824_s_at (11), 193459_s_at (11)
NM_001028133 175821_s_at (11), 193463_s_at (11)
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:10340083-10342286(-) 100.0 100.0
Public Domain and Genome References
Ensembl K11E8.1
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAC42326 Hypothetical protein K11E8.1d [Caenorhabditis elegans] emb|CAC42364.1| Hypothetical protein K11E8.1d [Caenorhabditis elegans] ref|NP_001023296.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] gb|AAD53949.1| calcium/calmodulin dependent protein kinase II [Caenorhabditis elegans] 0.0
blast CAC42323 Hypothetical protein K11E8.1g [Caenorhabditis elegans] emb|CAC42361.1| Hypothetical protein K11E8.1g [Caenorhabditis elegans] ref|NP_001023299.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] gb|AAF63320.1| calcium/calmodulin-dependent protein kinase II isoform B [Caenorhabditis elegans] 0.0
blast CAC42327 Hypothetical protein K11E8.1f [Caenorhabditis elegans] emb|CAC42365.1| Hypothetical protein K11E8.1f [Caenorhabditis elegans] ref|NP_001023298.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] gb|AAF63323.1| calcium/calmodulin-dependent protein kinase II isoform E [Caenorhabditis elegans] 0.0
blast CAC42329 Hypothetical protein K11E8.1l [Caenorhabditis elegans] emb|CAC42367.1| Hypothetical protein K11E8.1l [Caenorhabditis elegans] ref|NP_001023303.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] gb|AAF63325.1| calcium/calmodulin-dependent protein kinase II isoform G [Caenorhabditis elegans] 1.0E-175
blast CAA94244 Hypothetical protein K11E8.1c [Caenorhabditis elegans] emb|CAC42359.1| Hypothetical protein K11E8.1c [Caenorhabditis elegans] ref|NP_001023295.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] 1.0E-174
blast CAC42324 Hypothetical protein K11E8.1h [Caenorhabditis elegans] emb|CAC42362.1| Hypothetical protein K11E8.1h [Caenorhabditis elegans] ref|NP_001023300.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] gb|AAF63322.1| calcium/calmodulin-dependent protein kinase II isoform D [Caenorhabditis elegans] 1.0E-174
blast CAA94243 Hypothetical protein K11E8.1b [Caenorhabditis elegans] emb|CAC42357.1| Hypothetical protein K11E8.1b [Caenorhabditis elegans] ref|NP_001023294.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] 8.0E-75
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 6.0E-66
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-66
hanks 2.2.5 CaMK Group; CaMK II KIN1/SNF1/Nim1; SNF1 9.0E-22
hanks 2.1.5 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; DmCamKII 1.0E-137
hanks 2.1.5 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; DmCamKII 1.0E-138
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.3E-97
Pfam IPR000719 EMBL-EBI Protein kinase 8.6E-42
Sequence
Target Sequence 
>C. ELEGANS:187759_S_AT
aaccacacaccgcgttcagaaatttcgaagcgcaagtgggcatccgaggaatgttatata
ggtgagaagcgtcaacgggcaacacaaatccagtcgaaccttctcacccaattacaagaa
ggatcatcaaactatcatcatcagcagtatcgtccaccacttccattacttccaccacca
actgtagatcagcactatcttcagcaattagccatg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AACCACACACCGCGTTCAGAAATTT 365 147 331 Antisense
ATTTCGAAGCGCAAGTGGGCATCCG 393 17 352 Antisense
GCGCAAGTGGGCATCCGAGGAATGT 440 287 360 Antisense
GAAGCGTCAACGGGCAACACAAATC 397 343 396 Antisense
AACACAAATCCAGTCGAACCTTCTC 538 135 411 Antisense
GAACCTTCTCACCCAATTACAAGAA 597 345 426 Antisense
GGATCATCAAACTATCATCATCAGC 15 513 451 Antisense
TATCATCATCAGCAGTATCGTCCAC 247 659 463 Antisense
TACTTCCACCACCAACTGTAGATCA 484 645 497 Antisense
ACTGTAGATCAGCACTATCTTCAGC 576 97 511 Antisense
GCACTATCTTCAGCAATTAGCCATG 155 317 522 Antisense
Sequence Source Affymetrix Proprietary Database