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[187758_at]

Description Y43C5B.1 /REP_DB=WormBase Gene ID /WP=CE19156 /CHR=4 /FEA=Sanger Annotation /DEF=(HINXTON) TR:Q9XXE4 protein_id:CAA19512.1
Cluster 6grp_total > 82      4grp_total > 17      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 75
1 2 3 4 range
A 44.3
(-3)
A 		62.1
(0.1)
P 		79
(3)
P 		76.5
(2.6)
M 		35
B 42.9
(-0.5)
A 		58
(3)
P 		32
(-3)
A 		37.2
(-1.8)
A 		26
C 40.3
(-2.3)
A 		31.9
(-3)
A 		37.3
(-2.6)
A 		106.7
(3)
P 		75
avr 42.5
(-3) 		50.7
(-1.4) 		49.4
(-1.7) 		73.5
(3) 		31

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 64
1 2 3 4 5 6 range
A 11.7
(-3)
A 		27.4
(-1.1)
A 		58.4
(2.6)
A 		18.8
(-2.2)
A 		61.9
(3)
P 		27.3
(-1.1)
A 		50
B 27.5
(-0.9)
A 		28.5
(-0.7)
P 		43.3
(2.3)
A 		46.8
(3)
A 		44.2
(2.5)
A 		16.8
(-3)
A 		30
C 50.4
(0.9)
A 		49.3
(0.8)
P 		9
(-3)
A 		72.9
(3)
A 		34.1
(-0.6)
A 		34.5
(-0.6)
A 		64
avr 29.9
(-1.9) 		35.1
(-0.4) 		36.9
(0.1) 		46.2
(2.9) 		46.7
(3) 		26.2
(-3) 		21
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 13
1 2 3 4 range
A 16.1
(0.1)
A 		13.5
(-1.5)
P 		20.6
(3)
P 		11.2
(-3)
M 		9
B 13.7
(2.5)
A 		14.3
(3)
P 		7.4
(-3)
A 		7.9
(-2.6)
A 		7
C 13.3
(-0.2)
A 		9.2
(-3)
A 		13
(-0.4)
A 		18
(3)
P 		9
avr 14.4
(3) 		12.3
(-3) 		13.7
(1) 		12.4
(-2.7) 		2

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 17
1 2 3 4 5 6 range
A 2.2
(-3)
A 		9.7
(-0.3)
A 		12.7
(0.8)
A 		4.8
(-2.1)
A 		18.7
(3)
P 		6.6
(-1.4)
A 		17
B 9.6
(-1.3)
A 		9.5
(-1.4)
P 		10.5
(-0.8)
A 		12.4
(0.1)
A 		18
(3)
A 		6.3
(-3)
A 		12
C 18.7
(3)
A 		15.1
(1.7)
P 		2.3
(-3)
A 		14.7
(1.5)
A 		11
(0.2)
A 		11.5
(0.4)
A 		16
avr 10.2
(-1.4) 		11.4
(-0.5) 		8.5
(-2.7) 		10.6
(-1.1) 		15.9
(3) 		8.1
(-3) 		8
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 187758_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9383
Sequence Type Exemplar sequence
Representative Public ID Y43C5B.1 NCBI
Target Description Y43C5B.1 /REP_DB=WormBase Gene ID /WP=CE19156 /CHR=4 /FEA=Sanger Annotation /DEF=(HINXTON) TR:Q9XXE4 protein_id:CAA19512.1
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Genome Target Overlap based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade B annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001028125, NM_001028123
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
K11E8.1b.3 ENSEMBL cdna:known chromosome:CEL140:IV:10338670:10348943:-1 gene:K11E8.1 None
NM_001028123 NCBI Caenorhabditis elegans UNCoordinated family member (unc-43) (unc-43) mRNA, complete cds. None
K11E8.1b.2 ENSEMBL cdna:known chromosome:CEL140:IV:10338670:10340528:-1 gene:K11E8.1 A 
K11E8.1b.1 ENSEMBL cdna:known chromosome:CEL140:IV:10338670:10340529:-1 gene:K11E8.1 A 
NM_001028125 NCBI Caenorhabditis elegans UNCoordinated family member (unc-43) (unc-43) mRNA, complete cds. None
K11E8.1d ENSEMBL cdna:known chromosome:CEL140:IV:10324241:10340517:-1 gene:K11E8.1 A 
K11E8.1l ENSEMBL cdna:known chromosome:CEL140:IV:10324241:10340528:-1 gene:K11E8.1 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:10340083-10342286(-) 100.0 100.0
Public Domain and Genome References
Ensembl K11E8.1
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAC42326 Hypothetical protein K11E8.1d [Caenorhabditis elegans] emb|CAC42364.1| Hypothetical protein K11E8.1d [Caenorhabditis elegans] ref|NP_001023296.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] gb|AAD53949.1| calcium/calmodulin dependent protein kinase II [Caenorhabditis elegans] 0.0
blast CAC42323 Hypothetical protein K11E8.1g [Caenorhabditis elegans] emb|CAC42361.1| Hypothetical protein K11E8.1g [Caenorhabditis elegans] ref|NP_001023299.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] gb|AAF63320.1| calcium/calmodulin-dependent protein kinase II isoform B [Caenorhabditis elegans] 0.0
blast CAC42327 Hypothetical protein K11E8.1f [Caenorhabditis elegans] emb|CAC42365.1| Hypothetical protein K11E8.1f [Caenorhabditis elegans] ref|NP_001023298.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] gb|AAF63323.1| calcium/calmodulin-dependent protein kinase II isoform E [Caenorhabditis elegans] 0.0
blast CAC42329 Hypothetical protein K11E8.1l [Caenorhabditis elegans] emb|CAC42367.1| Hypothetical protein K11E8.1l [Caenorhabditis elegans] ref|NP_001023303.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] gb|AAF63325.1| calcium/calmodulin-dependent protein kinase II isoform G [Caenorhabditis elegans] 1.0E-175
blast CAA94244 Hypothetical protein K11E8.1c [Caenorhabditis elegans] emb|CAC42359.1| Hypothetical protein K11E8.1c [Caenorhabditis elegans] ref|NP_001023295.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] 1.0E-174
blast CAC42324 Hypothetical protein K11E8.1h [Caenorhabditis elegans] emb|CAC42362.1| Hypothetical protein K11E8.1h [Caenorhabditis elegans] ref|NP_001023300.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] gb|AAF63322.1| calcium/calmodulin-dependent protein kinase II isoform D [Caenorhabditis elegans] 1.0E-174
blast CAA94243 Hypothetical protein K11E8.1b [Caenorhabditis elegans] emb|CAC42357.1| Hypothetical protein K11E8.1b [Caenorhabditis elegans] ref|NP_001023294.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] 8.0E-75
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 6.0E-66
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-66
hanks 2.2.5 CaMK Group; CaMK II KIN1/SNF1/Nim1; SNF1 9.0E-22
hanks 2.1.5 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; DmCamKII 1.0E-137
hanks 2.1.5 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; DmCamKII 1.0E-138
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.3E-97
Pfam IPR000719 EMBL-EBI Protein kinase 8.6E-42
Sequence
Target Sequence 
>C. ELEGANS:187758_AT
tctgaagcttgccgctattttcatcgcatttttatccgtgtcctgtctgcctttcttctt
cttttttctcccttctgcttcttttgcgttagcaggagccagcagcgtatgtgtgagccc
atacacaccatgcacagacatacacacaaccaccacagaaaaaagagagagagcttcttc
caacacaattcatcctcttcgtcttctatttttttaatgttggttgtgtccaaaaaaatg
agatggtttgttggccccaagaaccacacac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCTGAAGCTTGCCGCTATTTTCATC 210 609 70 Antisense
TTTCATCGCATTTTTATCCGTGTCC 266 673 88 Antisense
CCTTCTGCTTCTTTTGCGTTAGCAG 605 269 140 Antisense
TGCGTTAGCAGGAGCCAGCAGCGTA 555 557 154 Antisense
GAGCCAGCAGCGTATGTGTGAGCCC 349 385 165 Antisense
TGTGTGAGCCCATACACACCATGCA 512 555 179 Antisense
CACACCATGCACAGACATACACACA 480 195 193 Antisense
AAGAGAGAGAGCTTCTTCCAACACA 625 151 232 Antisense
CTCTTCGTCTTCTATTTTTTTAATG 647 229 264 Antisense
AATGAGATGGTTTGTTGGCCCCAAG 496 163 306 Antisense
TTTGTTGGCCCCAAGAACCACACAC 180 667 316 Antisense
Sequence Source Affymetrix Proprietary Database