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[187742_at]

Description D1014.9 /REP_DB=WormBase Gene ID /WP=CE07011 /CHR=5 /FEA=Sanger Annotation /DEF=(ST.LOUIS) TR:Q18920 protein_id:AAA96286.1
Cluster 6grp_highest_10_10 > 89      6grp_high1_10_10 > 99      4grp_high_8_8 > 25      6grp_highest_nonorm > 90      6grp_total > 94      4grp_total > 39      6grp_highest_sub > In      6grp_cgc > 78      6grp_cgc_sub > In      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 107
1 2 3 4 range
A 115.3
(3)
P 		48.3
(-3)
P 		77.2
(-0.4)
P 		85
(0.3)
A 		67
B 154.1
(3)
P 		69.8
(-1.7)
P 		46.8
(-3)
P 		84.3
(-0.9)
P 		107
C 136.2
(3)
P 		131.3
(2.2)
P 		97.1
(-3)
P 		98.7
(-2.8)
P 		39
avr 135.2
(3) 		83.1
(-2.1) 		73.7
(-3) 		89.3
(-1.5) 		62

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 137
1 2 3 4 5 6 range
A 106
(-3)
P 		138.5
(-0.8)
P 		152.5
(0.2)
P 		194.5
(3)
P 		170.9
(1.4)
P 		138.9
(-0.8)
P 		89
B 84.5
(-3)
P 		128.7
(-1.1)
P 		109.7
(-1.9)
P 		154.1
(0)
P 		221.6
(3)
P 		191.9
(1.7)
P 		137
C 160
(0.3)
P 		139.6
(-0.9)
P 		144
(-0.6)
P 		102.9
(-3)
P 		194.5
(2.3)
P 		207
(3)
P 		104
avr 116.8
(-3) 		135.6
(-1.6) 		135.4
(-1.6) 		150.5
(-0.4) 		195.7
(3) 		179.3
(1.8) 		79
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 39
1 2 3 4 range
A 42
(3)
P 		10.5
(-3)
P 		20.2
(-1.2)
P 		12.4
(-2.6)
A 		32
B 49.1
(3)
P 		17.2
(-2)
P 		10.8
(-3)
P 		18
(-1.9)
P 		38
C 45.1
(3)
P 		37.7
(1.4)
P 		33.8
(0.6)
P 		16.6
(-3)
P 		29
avr 45.4
(3) 		21.8
(-1.8) 		21.6
(-1.8) 		15.7
(-3) 		30

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 71
1 2 3 4 5 6 range
A 19.5
(-3)
P 		49.3
(2.6)
P 		33.2
(-0.4)
P 		49.3
(2.6)
P 		51.6
(3)
P 		33.8
(-0.3)
P 		32
B 29.4
(-2.7)
P 		42.8
(-1.5)
P 		26.6
(-3)
P 		40.8
(-1.7)
P 		90
(3)
P 		71.6
(1.3)
P 		63
C 59.3
(1.8)
P 		42.6
(-0.3)
P 		36.7
(-1)
P 		20.7
(-3)
P 		62.9
(2.2)
P 		69.3
(3)
P 		49
avr 36.1
(-2.4) 		44.9
(-0.9) 		32.2
(-3) 		36.9
(-2.2) 		68.2
(3) 		58.2
(1.3) 		36
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 187742_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.12341
Sequence Type Exemplar sequence
Representative Public ID D1014.9 NCBI
Target Description D1014.9 /REP_DB=WormBase Gene ID /WP=CE07011 /CHR=5 /FEA=Sanger Annotation /DEF=(ST.LOUIS) TR:Q18920 protein_id:AAA96286.1
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_072697(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_072697 NCBI Caenorhabditis elegans Suppressor of PResenilin defect family member (spr-1) (spr-1) mRNA, complete cds. 11/11 A 
SNAP00000031799 ENSEMBL cdna:SNAP chromosome:CEL140:V:8129482:8131940:-1 9/11 None
GENEFINDER00000031806 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:8129482:8131940:-1 11/11 None
D1014.8 ENSEMBL cdna:known chromosome:CEL140:V:8129336:8131943:-1 gene:D1014.8 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:8130783-8131941(-) 98.57 100.0
Public Domain and Genome References
Gene Title
Gene Symbol spr-1
Ensembl D1014.8
Entrez Gene 179192 Entrez gene
SwissProt Q18919 EMBL-EBI
WormBase CE27749 Wormbase
Functional Annotations
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3677 DNA binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_505098 Suppressor of PResenilin defect family member (spr-1) [Caenorhabditis elegans] gb|AAN59932.1| suppressor of presenilin defect [Caenorhabditis elegans] gb|AAA96286.2| Suppressor of presenilin defect protein 1 [Caenorhabditis elegans] sp|Q18919|SPR1_CAEEL Suppressor of presenilin 1 gb|AAN62581.1| suppressor of presenilin 1 [Caenorhabditis elegans] 0.0
blast T29614 hypothetical protein D1014.9 - Caenorhabditis elegans 1.0E-125
blast T29614 hypothetical protein D1014.9 - Caenorhabditis elegans 1.0E-104
blast AAF36052 Hypothetical protein Y74C9A.4a [Caenorhabditis elegans] ref|NP_490663.1| Y74C9A.4a [Caenorhabditis elegans] 8.0E-71
Protein Domains
Database ID Description E-Value
Pfam IPR001005 EMBL-EBI Myb DNA-binding domain 3.3E-7
Pfam IPR001005 EMBL-EBI Myb DNA-binding domain 6.9E-10
Pfam IPR000949 EMBL-EBI ELM2 domain 1.3E-11
Pfam IPR001005 EMBL-EBI Myb DNA-binding domain 6.9E-10
Pfam IPR001005 EMBL-EBI Myb DNA-binding domain 6.9E-10
Sequence
Target Sequence 
>C. ELEGANS:187742_AT
gaaaggcccactatcaaacacgaataaggaaatcaacgtaggaacagagtttcaagcgaa
aatcgcggatcttaatttaaatgataaagcatgtaatgaggatagagatgatcaagatga
actaatatggaatactccggaaactattgatgatgaaaagttagaagctttcatcagaga
atcatctgatcgatatcttattcctattgatagagctctgtatatcctaacaataaataa
cttcaattttgactcggccatagcagaagttgcacgacgtaatgaactgaaagatgtgtg
gacagatcaggaaattactctttttgagaattgttaccagattttcggcaaaaatttttc
acaaattagatcagcgctctgtcatcgatctcttcagtcaattgttcagttttattacga
atcaaaaaaacgtgtaaaatatctaaactttgtcaattcgaaatgtgatgatagtagtag
ttcggaagaaactgaaactccatctccatatcctgaagctattttcgagtcaatgtgtg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAAAGGCCCACTATCAAACACGAAT 93 361 306 Antisense
TCATCTGATCGATATCTTATTCCTA 56 621 487 Antisense
TAGAGCTCTGTATATCCTAACAATA 141 653 516 Antisense
CTTCAATTTTGACTCGGCCATAGCA 61 219 546 Antisense
GGCCATAGCAGAAGTTGCACGACGT 652 543 561 Antisense
GAGAATTGTTACCAGATTTTCGGCA 340 391 631 Antisense
TTCACAAATTAGATCAGCGCTCTGT 29 687 663 Antisense
CTCTGTCATCGATCTCTTCAGTCAA 78 233 682 Antisense
GATCTCTTCAGTCAATTGTTCAGTT 587 419 692 Antisense
CCATCTCCATATCCTGAAGCTATTT 475 271 805 Antisense
GAAGCTATTTTCGAGTCAATGTGTG 18 343 820 Antisense
Sequence Source Affymetrix Proprietary Database