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[187695_at]

Description Y110A2AL.13 /REP_DB=WormBase Gene ID /WP=CE25189 /TR=Q9N492 /GB=AAF60409.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation
Cluster 6grp_total > 29      4grp_total > 33      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 94
1 2 3 4 range
A 4.3
(-3)
A 		58.4
(3)
A 		25.5
(-0.6)
A 		11.9
(-2.2)
A 		54
B 10.1
(-3)
A 		98.2
(3)
A 		76.3
(1.5)
A 		70.5
(1.1)
A 		88
C 69.1
(2.1)
A 		30.2
(-3)
A 		64
(1.4)
A 		76
(3)
A 		46
avr 27.8
(-3) 		62.3
(3) 		55.3
(1.8) 		52.8
(1.3) 		35

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 113
1 2 3 4 5 6 range
A 60.1
(-3)
A 		95.9
(0.2)
P 		128.1
(3)
P 		75.8
(-1.6)
P 		64.3
(-2.6)
A 		100.3
(0.5)
A 		68
B 101.1
(3)
A 		87.3
(2)
A 		70.8
(0.9)
A 		14.8
(-3)
A 		88.9
(2.2)
P 		63
(0.4)
A 		86
C 86.8
(2.4)
A 		56.9
(-0.5)
A 		30.5
(-3)
A 		85.8
(2.3)
A 		93.3
(3)
A 		60.3
(-0.2)
A 		63
avr 82.7
(3) 		80
(2.3) 		76.5
(1.4) 		58.8
(-3) 		82.2
(2.9) 		74.5
(0.9) 		24
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 23
1 2 3 4 range
A 1.6
(-3)
A 		12.7
(3)
A 		6.7
(-0.2)
A 		1.7
(-2.9)
A 		11
B 3.2
(-3)
A 		24.2
(3)
A 		17.7
(1.1)
A 		15
(0.4)
A 		21
C 22.9
(3)
A 		8.7
(-3)
A 		22.3
(2.7)
A 		12.8
(-1.3)
A 		14
avr 9.2
(-3) 		15.2
(2.6) 		15.6
(3) 		9.8
(-2.4) 		6

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 32
1 2 3 4 5 6 range
A 11.1
(-3)
A 		34.1
(3)
P 		27.9
(1.4)
P 		19.2
(-0.9)
P 		19.4
(-0.8)
A 		24.4
(0.5)
A 		23
B 35.2
(2.8)
A 		29
(1.7)
A 		17.2
(-0.5)
A 		3.9
(-3)
A 		36.1
(3)
P 		23.5
(0.7)
A 		32
C 32.2
(3)
A 		17.4
(-0.6)
A 		7.8
(-3)
A 		17.2
(-0.7)
A 		30.2
(2.5)
A 		20.2
(0)
A 		24
avr 26.2
(2.1) 		26.8
(2.3) 		17.6
(-1.3) 		13.4
(-3) 		28.6
(3) 		22.7
(0.7) 		15
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 187695_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.4972
Sequence Type Exemplar sequence
Representative Public ID Y110A2AL.13 NCBI
Target Description Y110A2AL.13 /REP_DB=WormBase Gene ID /WP=CE25189 /TR=Q9N492 /GB=AAF60409.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_061992(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_061992 NCBI Caenorhabditis elegans Y110A2AL.13 (Y110A2AL.13) mRNA, complete cds. 11/11 None
SNAP00000036291 ENSEMBL cdna:SNAP chromosome:CEL140:II:2878953:2889002:-1 11/11 None
Y110A2AL.13 ENSEMBL cdna:known chromosome:CEL140:II:2886389:2889002:-1 gene:Y110A2AL.13 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000036304 1/11 Cross Hyb Matching Probes None
GENEFINDER00000036306 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:2886387-2889001(-) 100.0 100.0
Public Domain and Genome References
Gene Title
Ensembl Y110A2AL.13
Entrez Gene 190941 Entrez gene
SwissProt Q9N492 EMBL-EBI
WormBase CE25189 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:18233_AT peptidyl-prolyl cis-trans isomerase (PIN1) / cyclophilin / rotamase at
ATH1-121501:265818_AT peptidyl-prolyl cis-trans isomerase (PIN1) / cyclophilin / rotamase at
CANINE:1583802_AT similar to Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Rotamase Pin1) (PPIase Pin1) cfa
CANINE_2:CFA.6071.1.A1_AT similar to Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Rotamase Pin1) (PPIase Pin1) cfa
CANINE_2:CFAAFFX.27516.1.S1_S_AT similar to Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Rotamase Pin1) (PPIase Pin1) cfa
DROSOPHILA_2:1636396_AT dodo dm
DROSGENOME1:143804_AT dodo dm
HG-U133_PLUS_2:202927_AT protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 hs
HG-U133A:202927_AT protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 hs
HG-FOCUS:202927_AT protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 hs
HG-U133A_2:202927_AT protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 hs
HU35KSUBD:RC_AA399542_F_AT protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 hs
HU35KSUBD:RC_AA399542_R_AT protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 hs
HUGENEFL:U49070_AT protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 hs
U133_X3P:G5453897_3P_X_AT protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 hs
U133_X3P:G5453897_3P_S_AT protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 hs
U133_X3P:G5453897_3P_AT protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 hs
U133_X3P:202927_3P_AT protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 hs
HG-U95AV2:40421_AT protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 hs
HG-U95C:63705_F_AT protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 hs
HG-U95D:80754_AT protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 hs
HG-U95D:85979_AT Protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 hs
MU11KSUBB:MSA.14362.0_S_AT protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 mm
MU11KSUBB:W45768_S_AT protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 mm
MG-U74AV2:101492_AT protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 mm
MOE430A:1416228_AT protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 mm
MOUSE430A_2:1416228_AT protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 mm
MOUSE430_2:1416228_AT protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 mm
RG-U34A:RC_AA800175_AT protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 (predicted) rn
RG-U34B:RC_AA962972_AT protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 (predicted) rn
RAE230A:1371449_AT protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 (predicted) rn
RAT230_2:1371449_AT protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 (predicted) rn
YEAST_2:1773302_AT Peptidylprolyl-cis/trans-isomerase (PPIase) specific for phosphorylated serine and threonine residues N-terminal to proline; regulates phosphorylation of the RNA polymerase II large subunit (Rpo21p) C-terminal domain Sc
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
16853 isomerase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAF60407 Hypothetical protein Y110A2AL.12a [Caenorhabditis elegans] ref|NP_001022407.1| Y110A2AL.12a [Caenorhabditis elegans] 1.0E-154
blast AAF60406 Hypothetical protein Y110A2AL.12b [Caenorhabditis elegans] ref|NP_001022408.1| Y110A2AL.12b [Caenorhabditis elegans] 1.0E-126
blast AAF60409 Hypothetical protein Y110A2AL.13 [Caenorhabditis elegans] ref|NP_494393.1| Y110A2AL.13 [Caenorhabditis elegans] 7.0E-94
blast CAE72445 Hypothetical protein CBG19615 [Caenorhabditis briggsae] 7.0E-89
blast CAE72446 Hypothetical protein CBG19616 [Caenorhabditis briggsae] 4.0E-78
blast AAH59553 Protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 [Danio rerio] ref|NP_957042.1| protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 [Danio rerio] 4.0E-45
Protein Domains
Database ID Description E-Value
Pfam IPR000297 EMBL-EBI PpiC-type peptidyl-prolyl cis-trans isomerase 3.3E-30
Pfam IPR001202 EMBL-EBI WW/Rsp5/WWP domain 1.5E-12
Pfam IPR000297 EMBL-EBI PpiC-type peptidyl-prolyl cis-trans isomerase 7.0E-33
Pfam IPR009447 EMBL-EBI GWT1 2.2E-82
Trans Membrane
ID Number Of Domains Domain Boundaries
SNAP00000036291 6 182-204,219-238,269-291,311-333,353-370,385-404
Sequence
Target Sequence 
>C. ELEGANS:187695_AT
attcgctgccagccggatgggaaaagcgtcagagccgctcgaatgatcgcgtctactact
tcaacacggccaccggccgcagccaatgggagcgcccagacgagtcggcgtttggaaaag
gaagcgagctaaaatccgtccaatgccttcatttgctcgtaaaacacgatggaagccgta
atccatcgtcttggcggtccgatcacatcacaagatccaaggatgacgcgattaacatcc
tcaaaagtgcggatttgcggaattttcattacgaaaaggagctgaaagatgcgtcgaaca
ttgagggaaaattccgtgaactcgccaaacaattcagcgattgcagttcggcaaaacgtg
gcggagatcttgggccattcgaacgtcgtcaaatgcagaaaccattcgaagacgcctcat
ttgcactg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATTCGCTGCCAGCCGGATGGGAAAA 581 7 23 Antisense
AGAGCCGCTCGAATGATCGCGTCTA 34 71 53 Antisense
GCCCAGACGAGTCGGCGTTTGGAAA 45 287 116 Antisense
AGCGAGCTAAAATCCGTCCAATGCC 116 73 145 Antisense
AATGCCTTCATTTGCTCGTAAAACA 311 167 164 Antisense
TCTTGGCGGTCCGATCACATCACAA 551 617 211 Antisense
GAAAATTCCGTGAACTCGCCAAACA 480 353 329 Antisense
TGCAGTTCGGCAAAACGTGGCGGAG 561 569 364 Antisense
CGTGGCGGAGATCTTGGGCCATTCG 360 243 379 Antisense
GGGCCATTCGAACGTCGTCAAATGC 134 491 394 Antisense
ATTCGAAGACGCCTCATTTGCACTG 416 7 426 Antisense
Sequence Source Affymetrix Proprietary Database