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[187692_at]

Description C05D10.2 /REP_DB=WormBase Gene ID /WP=CE01125 /TR=SW:Q11179 /GB=AAA20987.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 60      6grp_high1_10_10 > 07      4grp_highest_8_8 > 62      4grp_high_8_8 > 18      6grp_highest_nonorm > 70      6grp_total > 08      4grp_total > 29      6grp_highest_sub > De      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 174
1 2 3 4 range
A 361.5
(0.5)
P 		349.7
(-0)
P 		281.8
(-3)
P 		419.9
(3)
P 		138
B 361.9
(3)
P 		245.7
(-3)
P 		312.6
(0.5)
P 		284.8
(-1)
P 		116
C 334
(1.2)
P 		370.3
(3)
P 		250.3
(-3)
P 		331.1
(1)
P 		120
avr 352.5
(3) 		321.9
(0.4) 		281.6
(-3) 		345.3
(2.4) 		71

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 341
1 2 3 4 5 6 range
A 481.4
(3)
P 		241.1
(-1.5)
P 		195.1
(-2.3)
P 		160
(-3)
P 		329.8
(0.2)
P 		222.1
(-1.8)
P 		321
B 394.1
(3)
P 		262.5
(-0.3)
P 		251.1
(-0.5)
P 		349.2
(1.9)
P 		180.8
(-2.3)
P 		151.5
(-3)
P 		243
C 304.9
(2.8)
P 		310.6
(3)
P 		211.7
(-0.5)
P 		263.6
(1.3)
P 		145.6
(-2.8)
P 		140.3
(-3)
P 		170
avr 393.5
(3) 		271.4
(-0.3) 		219.3
(-1.7) 		257.6
(-0.7) 		218.7
(-1.7) 		171.3
(-3) 		222
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 76
1 2 3 4 range
A 131.6
(3)
P 		75.9
(-1.8)
P 		73.7
(-2)
P 		61.5
(-3)
P 		70
B 115.4
(3)
P 		60.7
(-3)
P 		72.4
(-1.7)
P 		60.7
(-3)
P 		55
C 110.6
(3)
P 		106.5
(2.6)
P 		87.2
(0.4)
P 		55.8
(-3)
P 		55
avr 119.2
(3) 		81
(-0.8) 		77.8
(-1.1) 		59.3
(-3) 		60

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 97
1 2 3 4 5 6 range
A 88.7
(1.9)
P 		85.8
(1.6)
P 		42.5
(-2.8)
P 		40.6
(-3)
P 		99.5
(3)
P 		54.1
(-1.6)
P 		59
B 137.1
(3)
P 		87.4
(-0.7)
P 		61
(-2.7)
P 		92.5
(-0.3)
P 		73.5
(-1.7)
P 		56.5
(-3)
P 		81
C 113
(3)
P 		94.8
(1.3)
P 		53.9
(-2.4)
P 		53
(-2.5)
P 		47.1
(-3)
P 		47
(-3)
P 		66
avr 112.9
(3) 		89.3
(0.7) 		52.5
(-3) 		62
(-2.1) 		73.4
(-0.9) 		52.5
(-3) 		60
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 187692_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.7759
Sequence Type Exemplar sequence
Representative Public ID C05D10.2 NCBI
Target Description C05D10.2 /REP_DB=WormBase Gene ID /WP=CE01125 /TR=SW:Q11179 /GB=AAA20987.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_171144(11), NM_171145(10)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_171144 NCBI Caenorhabditis elegans C05D10.2a (C05D10.2) mRNA, complete cds. 11/11 None
NM_171145 NCBI Caenorhabditis elegans C05D10.2c (C05D10.2) mRNA, complete cds. 10/11 None
GENEFINDER00000011504 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:6067832:6071733:1 11/11 None
SNAP00000011484 ENSEMBL cdna:SNAP chromosome:CEL140:III:6069995:6071733:1 11/11 None
C05D10.2a ENSEMBL cdna:known chromosome:CEL140:III:6067798:6072017:1 gene:C05D10.2 11/11 None
C05D10.2c ENSEMBL cdna:known chromosome:CEL140:III:6067832:6072009:1 gene:C05D10.2 10/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Splice Variants
Entrez Total Refseq Isoforms Total Detected By This Probeset Refseq Probesets
175857 3 2 NM_171144 187692_at (11)
NM_171145 187692_at (10)
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:6067830-6071732(+) 100.0 100.0
Public Domain and Genome References
Ensembl C05D10.2
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast AAA20987 Hypothetical protein C05D10.2a [Caenorhabditis elegans] ref|NP_741165.1| C05D10.2a [Caenorhabditis elegans] sp|Q11179|YPC2_CAEEL Putative serine/threonine-protein kinase C05D10.2 in chromosome III 0.0
blast H88473 protein C05D10.2 [imported] - Caenorhabditis elegans 0.0
blast CAE73644 Hypothetical protein CBG21144 [Caenorhabditis briggsae] 0.0
blast AAM15543 Hypothetical protein C05D10.2c [Caenorhabditis elegans] ref|NP_741166.1| C05D10.2c [Caenorhabditis elegans] 0.0
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 1.0E-65
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 4.0E-66
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 6.0E-67
hanks 3.1.1 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; CDC2Hs 1.0E-70
hanks 3.1.1 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; CDC2Hs 9.0E-71
hanks 3.1.1 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; CDC2Hs 4.0E-72
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.9E-84
Pfam IPR000719 EMBL-EBI Protein kinase 2.6E-82
Pfam IPR000719 EMBL-EBI Protein kinase 3.8E-30
Sequence
Target Sequence 
>C. ELEGANS:187692_AT
gttgaacaatgcttggtacatccatatgtggtacaatttcataatccatcagaagaacca
gtactcaactatgaagtttatccaccacttccggatcatattcaattgagtattgacgat
tatcgtgatcgattgtatgagatgattgatgaaaagaaggccagttttaagaggatacaa
catgaaaagatccgaccttacggcgaagataagagtcgtgctccgattgctcaggctgaa
tgcagtgatactgattacgatacggcaagaagcttacaaagaacaacaagcatggataag
aataatagtagttcgcatgatagtagttctggaactttaagagagcgagccgcttcagct
gaaagtcgaacctcaaaagatagcaacggagagatgagaaatgggaatgggaatactcca
agtagtatcaagcaacgtcgtcgttctgtcgaaagagctcgattatttgcaaatatcaag
ccttccaagatcctt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTTGAACAATGCTTGGTACATCCAT 487 437 913 Antisense
TTTATCCACCACTTCCGGATCATAT 127 675 989 Antisense
AAAGATCCGACCTTACGGCGAAGAT 499 121 1098 Antisense
GATAAGAGTCGTGCTCCGATTGCTC 547 421 1120 Antisense
GCTCCGATTGCTCAGGCTGAATGCA 216 297 1132 Antisense
GCAGTGATACTGATTACGATACGGC 259 311 1154 Antisense
TAAGAGAGCGAGCCGCTTCAGCTGA 423 635 1250 Antisense
GCTTCAGCTGAAAGTCGAACCTCAA 255 303 1264 Antisense
GTAGTATCAAGCAACGTCGTCGTTC 159 453 1334 Antisense
GTCGTCGTTCTGTCGAAAGAGCTCG 277 473 1349 Antisense
AAATATCAAGCCTTCCAAGATCCTT 567 115 1383 Antisense
Sequence Source Affymetrix Proprietary Database