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[187442_s_at]

Description Y37D8A.1 /REP_DB=WormBase Gene ID /WP=CE20206 /TR=SW:Q9XWV3 /GB=CAA21538.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 91      6grp_high1_10_10 > 08      4grp_highest_8_8 > 16      4grp_high_8_8 > 60      6grp_highest_nonorm > 75      6grp_total > 19      4grp_total > 59      6grp_cgc > 0      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 587
1 2 3 4 range
A 783.5
(1.6)
P 		872.7
(2.8)
P 		889.9
(3)
P 		424
(-3)
P 		466
B 718.8
(0.6)
P 		790.6
(1.4)
P 		932.4
(3)
P 		388
(-3)
P 		544
C 811.4
(2)
P 		885.9
(2.8)
P 		902.2
(3)
P 		345.7
(-3)
P 		557
avr 771.2
(1.4) 		849.7
(2.3) 		908.2
(3) 		385.9
(-3) 		522

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 327
1 2 3 4 5 6 range
A 895.3
(1.5)
P 		866.4
(0.7)
P 		729
(-3)
P 		949
(3)
P 		802.7
(-1)
P 		805.5
(-0.9)
P 		220
B 819.6
(0.2)
P 		701.3
(-3)
P 		796.3
(-0.4)
P 		790.3
(-0.6)
P 		924
(3)
P 		727.3
(-2.3)
P 		223
C 999.1
(3)
P 		672.6
(-3)
P 		834.8
(-0)
P 		803.6
(-0.6)
P 		840.7
(0.1)
P 		845.5
(0.2)
P 		327
avr 904.7
(3) 		746.8
(-3) 		786.7
(-1.5) 		847.6
(0.8) 		855.8
(1.1) 		792.8
(-1.3) 		158
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 256
1 2 3 4 range
A 285.3
(3)
P 		189.4
(0.4)
P 		232.6
(1.6)
P 		62.1
(-3)
P 		223
B 229.2
(3)
P 		195.3
(1.6)
P 		216.1
(2.5)
P 		82.7
(-3)
P 		147
C 268.6
(1.9)
P 		254.7
(1.6)
P 		314.4
(3)
P 		58.3
(-3)
P 		256
avr 261
(3) 		213.1
(1.5) 		254.4
(2.8) 		67.7
(-3) 		193

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 217
1 2 3 4 5 6 range
A 165
(-2.8)
P 		308.1
(3)
P 		158.8
(-3)
P 		240.7
(0.3)
P 		242.2
(0.4)
P 		196.1
(-1.5)
P 		149
B 285.2
(0)
P 		233.4
(-1.7)
P 		193.4
(-3)
P 		209.3
(-2.5)
P 		375.4
(3)
P 		271.2
(-0.4)
P 		182
C 370.3
(3)
P 		205.2
(-1.7)
P 		212.5
(-1.5)
P 		161.6
(-3)
P 		272
(0.2)
P 		283
(0.5)
P 		209
avr 273.5
(1.7) 		248.9
(0.4) 		188.2
(-3) 		203.9
(-2.1) 		296.5
(3) 		250.1
(0.4) 		108
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 187442_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.7386
Sequence Type Exemplar sequence
Representative Public ID Y37D8A.1 NCBI
Target Description Y37D8A.1 /REP_DB=WormBase Gene ID /WP=CE20206 /TR=SW:Q9XWV3 /GB=CAA21538.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_067266(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_067266 NCBI Caenorhabditis elegans ARp2/3 compleX component family member (arx-5) (arx-5) mRNA, complete cds. 11/11 None
SNAP00000028768 ENSEMBL cdna:SNAP chromosome:CEL140:III:12816799:12817969:-1 11/11 None
GENEFINDER00000028791 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:12817521:12817969:-1 9/11 None
Y37D8A.1 ENSEMBL cdna:known chromosome:CEL140:III:12816711:12817975:-1 gene:Y37D8A.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:12816794-12817965(-) 100.0 100.0
Public Domain and Genome References
Gene Title
Gene Symbol arx-5
Ensembl Y37D8A.1
Entrez Gene 176697 Entrez gene
SwissProt Q9XWV3 EMBL-EBI
WormBase CE20206 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:264220_AT ARP2/3 complex 21 kDa subunit family at
ATGENOME1:12014_AT ARP2/3 complex 21 kDa subunit family at
CANINE:1599909_AT similar to Actin-related protein 2/3 complex subunit 3 (ARP2/3 complex 21 kDa subunit) (p21-ARC) cfa
CANINE:1586960_AT similar to Actin-related protein 2/3 complex subunit 3 (ARP2/3 complex 21 kDa subunit) (p21-ARC) cfa
CANINE_2:CFAAFFX.13399.1.S1_S_AT similar to Actin-related protein 2/3 complex subunit 3 (ARP2/3 complex 21 kDa subunit) (p21-ARC) cfa
DROSOPHILA_2:1636821_AT dm
DROSOPHILA_2:1638092_A_AT dm
DROSOPHILA_2:1626556_AT dm
DROSGENOME1:149979_AT dm
CHICKEN:GGA.12641.1.S1_AT actin related protein 2/3 complex, subunit 3, 21kDa gga
HG-U95AV2:35810_AT actin related protein 2/3 complex, subunit 3, 21kDa hs
HG-U133A:208736_AT actin related protein 2/3 complex, subunit 3, 21kDa hs
HG-U133_PLUS_2:208736_AT actin related protein 2/3 complex, subunit 3, 21kDa hs
HG-U133A_2:208736_AT actin related protein 2/3 complex, subunit 3, 21kDa hs
HG-FOCUS:208736_AT actin related protein 2/3 complex, subunit 3, 21kDa hs
HU35KSUBA:AF006086_AT actin related protein 2/3 complex, subunit 3, 21kDa hs
HU35KSUBC:RC_C14083_F_AT actin related protein 2/3 complex, subunit 3, 21kDa hs
HU35KSUBD:RC_H73961_F_AT actin related protein 2/3 complex, subunit 3, 21kDa hs
U133_X3P:G2209346_3P_S_AT actin related protein 2/3 complex, subunit 3, 21kDa hs
MU11KSUBA:AA408672_RC_S_AT actin related protein 2/3 complex, subunit 3 mm
MG-U74AV2:95434_AT actin related protein 2/3 complex, subunit 3 mm
MOE430A:1448279_AT actin related protein 2/3 complex, subunit 3 mm
MOUSE430A_2:1448279_AT actin related protein 2/3 complex, subunit 3 mm
MOUSE430_2:1448279_AT actin related protein 2/3 complex, subunit 3 mm
RG-U34B:RC_AA946275_AT actin related protein 2/3 complex, subunit 3 (predicted) rn
RAE230A:1371977_AT actin related protein 2/3 complex, subunit 3 (predicted) rn
RAT230_2:1371977_AT actin related protein 2/3 complex, subunit 3 (predicted) rn
YEAST_2:1775523_AT Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
30833 regulation of actin filament polymerization inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5856 cytoskeleton inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA21538 Hypothetical protein Y37D8A.1 [Caenorhabditis elegans] ref|NP_499667.1| ARp2/3 compleX component family member (arx-5) [Caenorhabditis elegans] sp|Q9XWV3|ARPC3_CAEEL Probable actin-related protein 2/3 complex subunit 3 (ARP2/3 complex 21 kDa subunit) (p21-ARC) 1.0E-105
blast CAE69537 Hypothetical protein CBG15746 [Caenorhabditis briggsae] 1.0E-101
blast CAE68892 Hypothetical protein CBG14863 [Caenorhabditis briggsae] 2.0E-92
blast CAA21538 Hypothetical protein Y37D8A.1 [Caenorhabditis elegans] ref|NP_499667.1| ARp2/3 compleX component family member (arx-5) [Caenorhabditis elegans] sp|Q9XWV3|ARPC3_CAEEL Probable actin-related protein 2/3 complex subunit 3 (ARP2/3 complex 21 kDa subunit) (p21-ARC) 6.0E-45
Protein Domains
Database ID Description E-Value
Pfam IPR007204 EMBL-EBI ARP2/3 complex, 21 kDa p21-Arc subunit 1.0E-126
Pfam IPR007204 EMBL-EBI ARP2/3 complex, 21 kDa p21-Arc subunit 2.1E-70
Sequence
Target Sequence 
>C. ELEGANS:187442_S_AT
ggcataccactcaaaattcgacactgaactcaaagttttgccattgggcaacacaaatat
gggaaaacttccgattcgaaccaatttcaagggtccagcgcctcaaaccaatcaggatga
catcatcgacgaagcgctcacctacttcaagccgaacatctttttccgcgaatttgagat
caaaggtcccgcggaccgtacaatgatctatctcatcttctacatcaccgagtgcctcag
aaaattgcaaaaaagcccaaacaagatagccggccaaaaggatcttcacgccttggctct
cagtcatttgcttccaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGCATACCACTCAAAATTCGACACT 231 535 18 Antisense
GAACCAATTTCAAGGGTCCAGCGCC 495 345 95 Antisense
GGATGACATCATCGACGAAGCGCTC 288 513 132 Antisense
CACCTACTTCAAGCCGAACATCTTT 504 201 156 Antisense
GAACATCTTTTTCCGCGAATTTGAG 301 351 171 Antisense
TTTGAGATCAAAGGTCCCGCGGACC 277 663 190 Antisense
CGCGGACCGTACAATGATCTATCTC 221 255 207 Antisense
TGATCTATCTCATCTTCTACATCAC 383 565 221 Antisense
TCTACATCACCGAGTGCCTCAGAAA 304 613 236 Antisense
CAAAAGGATCTTCACGCCTTGGCTC 227 191 292 Antisense
TTGGCTCTCAGTCATTTGCTTCCAA 409 709 310 Antisense
Sequence Source Affymetrix Proprietary Database