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[186767_s_at]

Description ZK1248.10 /REP_DB=WormBase Gene ID /WP=CE02894 /TR=Q23419 /GB=AAC71091.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 95      6grp_high1_10_10 > 68      4grp_highest_8_8 > 43      4grp_high_8_8 > 24      6grp_highest_nonorm > 83      6grp_total > 69      4grp_total > 47      6grp_highest_sub > Cu      6grp_high1_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 293
1 2 3 4 range
A 578.7
(3)
P 		290.6
(-3)
P 		359.5
(-1.6)
P 		405.8
(-0.6)
P 		288
B 583.1
(3)
P 		350.5
(-2.9)
P 		391.2
(-1.9)
P 		348.4
(-3)
P 		235
C 500.6
(3)
P 		304.5
(-3)
P 		341.4
(-1.9)
P 		322
(-2.5)
P 		196
avr 554.1
(3) 		315.2
(-3) 		364
(-1.8) 		358.7
(-1.9) 		239

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 477
1 2 3 4 5 6 range
A 410.6
(-0.6)
P 		421.4
(-0.4)
P 		417.5
(-0.5)
P 		285.2
(-3)
P 		470.3
(0.5)
P 		604.5
(3)
P 		319
B 516.4
(0.4)
P 		525.6
(0.5)
P 		244.7
(-3)
P 		267.3
(-2.7)
P 		394.6
(-1.1)
P 		722.1
(3)
P 		477
C 448.6
(0.1)
P 		419.6
(-0.8)
P 		366.2
(-2.5)
P 		429.2
(-0.5)
P 		350.2
(-3)
P 		540
(3)
P 		190
avr 458.5
(-0.3) 		455.5
(-0.4) 		342.8
(-2.7) 		327.2
(-3) 		405
(-1.4) 		622.2
(3) 		295
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 156
1 2 3 4 range
A 210.7
(3)
P 		63.1
(-2.9)
P 		94
(-1.6)
P 		59.4
(-3)
P 		151
B 185.9
(3)
P 		86.6
(-2.3)
P 		90.6
(-2.1)
P 		74.3
(-3)
P 		112
C 165.7
(3)
P 		87.5
(-1.2)
P 		119
(0.5)
P 		54.3
(-3)
P 		111
avr 187.4
(3) 		79.1
(-2.2) 		101.2
(-1.1) 		62.7
(-3) 		125

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 210
1 2 3 4 5 6 range
A 75.7
(-2.7)
P 		149.9
(3)
P 		90.9
(-1.6)
P 		72.3
(-3)
P 		141.9
(2.4)
P 		147.2
(2.8)
P 		78
B 179.7
(0.4)
P 		175
(0.3)
P 		59.4
(-3)
P 		70.8
(-2.7)
P 		160.3
(-0.1)
P 		269.3
(3)
P 		210
C 166.3
(2.1)
P 		128
(-0.4)
P 		93.2
(-2.6)
P 		86.3
(-3)
P 		113.3
(-1.3)
P 		180.8
(3)
P 		95
avr 140.6
(0.1) 		151
(0.6) 		81.2
(-2.8) 		76.5
(-3) 		138.5
(0) 		199.1
(3) 		123
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 186767_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.4685
Sequence Type Exemplar sequence
Representative Public ID ZK1248.10 NCBI
Target Description ZK1248.10 /REP_DB=WormBase Gene ID /WP=CE02894 /TR=Q23419 /GB=AAC71091.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_062755(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_062755 NCBI Caenorhabditis elegans ZK1248.10 (ZK1248.10) mRNA, complete cds. 11/11 A 
SNAP00000041376 ENSEMBL cdna:SNAP chromosome:CEL140:II:5824051:5827391:-1 11/11 None
GENEFINDER00000041389 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:5824022:5827391:-1 11/11 None
ZK1248.10 ENSEMBL cdna:known chromosome:CEL140:II:5823388:5827408:-1 gene:ZK1248.10 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:5824047-5827388(-) 100.0 100.0
Public Domain and Genome References
Gene Title
Ensembl ZK1248.10
Entrez Gene 173986 Entrez gene
SwissProt Q23419 EMBL-EBI
WormBase CE29155 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.21845.1.S1_AT similar to ZK1248.10 cfa
CHICKEN:GGAAFFX.2074.1.S1_AT similar to mKIAA1055 protein gga
HG-U133_PLUS_2:215640_AT KIAA1055 protein hs
HG-U133A_2:215640_AT KIAA1055 protein hs
HG-U133A:215640_AT KIAA1055 protein hs
HU35KSUBD:RC_R26293_AT KIAA1055 protein hs
HU35KSUBD:RC_H28210_AT KIAA1055 protein hs
HU35KSUBD:RC_AA447707_S_AT KIAA1055 protein hs
U133_X3P:HS.306386.0.S1_3P_AT KIAA1055 protein hs
U133_X3P:HS.126084.0.A1_3P_A_AT KIAA1055 protein hs
HG-U133A_2:212796_S_AT KIAA1055 protein hs
HG-U133_PLUS_2:212796_S_AT KIAA1055 protein hs
HG-U133A:212796_S_AT KIAA1055 protein hs
HG-U95AV2:39400_AT KIAA1055 protein hs
HG-U95E:68481_AT KIAA1055 protein hs
HG-U133_PLUS_2:215951_AT KIAA1055 protein hs
HG-U133A_2:215951_AT KIAA1055 protein hs
HG-U133A:215951_AT KIAA1055 protein hs
HG-U133_PLUS_2:230377_S_AT KIAA1055 protein hs
HG-U133B:230377_S_AT KIAA1055 protein hs
HG-U95D:91796_AT KIAA1055 protein hs
U133_X3P:HS.126084.1.A1_3P_AT KIAA1055 protein hs
MG-U74BV2:113749_AT RIKEN cDNA 1810061M12 gene mm
MG-U74BV2:107521_AT RIKEN cDNA 1810061M12 gene mm
MG-U74CV2:167050_R_AT RIKEN cDNA 1810061M12 gene mm
MG-U74CV2:167019_I_AT RIKEN cDNA 1810061M12 gene mm
MOE430B:1428508_AT RIKEN cDNA 1810061M12 gene mm
MOUSE430_2:1428508_AT RIKEN cDNA 1810061M12 gene mm
MU19KSUBB:TC31995_AT RIKEN cDNA 1810061M12 gene mm
MOUSE430_2:1444493_AT RIKEN cDNA 1810061M12 gene, mRNA (cDNA clone IMAGE:4039019) mm
MOE430B:1444493_AT RIKEN cDNA 1810061M12 gene, mRNA (cDNA clone IMAGE:4039019) mm
MU19KSUBA:TC19188_AT RIKEN cDNA 1810061M12 gene, mRNA (cDNA clone IMAGE:4039019) mm
MU19KSUBB:TC30945_AT RIKEN cDNA 1810061M12 gene, mRNA (cDNA clone IMAGE:4039019) mm
RAE230A:1372748_AT similar to KIAA1055 protein (predicted) rn
RAT230_2:1372748_AT similar to KIAA1055 protein (predicted) rn
RG-U34A:RC_AA799507_AT similar to KIAA1055 protein (predicted) rn
RG-U34B:RC_AI059020_AT Similar to KIAA1055 protein (predicted) rn
RG-U34C:RC_AI228491_AT Similar to KIAA1055 protein (predicted) rn
Protein Similarities
Method ID Description E-Value
blast AAC71091 Hypothetical protein ZK1248.10 [Caenorhabditis elegans] ref|NP_495156.1| ZK1248.10 [Caenorhabditis elegans] 0.0
blast CAE59197 Hypothetical protein CBG02508 [Caenorhabditis briggsae] 0.0
blast XP_693084 PREDICTED: similar to mKIAA1055 protein [Danio rerio] 1.0E-76
Protein Domains
Database ID Description E-Value
Pfam IPR000195 EMBL-EBI RabGAP/TBC domain 1.3E-47
Pfam IPR001849 EMBL-EBI Pleckstrin-like 1.1E-21
Sequence
Target Sequence 
>C. ELEGANS:186767_S_AT
agttcatcaatgtctcagcaaagctcaagaacatatcattgacttcaagtcgctagctca
agtggcattcaacgaactgaatccgttccctcagaagactatagaaactaaacgacaact
ctatttgaca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AGTTCATCAATGTCTCAGCAAAGCT 152 65 2424 Antisense
TCATCAATGTCTCAGCAAAGCTCAA 257 621 2427 Antisense
TCAGCAAAGCTCAAGAACATATCAT 6 625 2438 Antisense
GAACATATCATTGACTTCAAGTCGC 162 351 2452 Antisense
TTGACTTCAAGTCGCTAGCTCAAGT 177 703 2462 Antisense
AAGTCGCTAGCTCAAGTGGCATTCA 204 159 2470 Antisense
CTCAAGTGGCATTCAACGAACTGAA 258 227 2480 Antisense
TCAACGAACTGAATCCGTTCCCTCA 403 631 2492 Antisense
GAATCCGTTCCCTCAGAAGACTATA 431 327 2502 Antisense
TCCGTTCCCTCAGAAGACTATAGAA 58 595 2505 Antisense
AACTAAACGACAACTCTATTTGACA 13 141 2529 Antisense
Sequence Source Affymetrix Proprietary Database