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[186766_at]

Description ZK1248.10 /REP_DB=WormBase Gene ID /WP=CE02894 /TR=Q23419 /GB=AAC71091.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 94      6grp_high1_10_10 > 69      4grp_highest_8_8 > 51      4grp_high_8_8 > 32      6grp_highest_nonorm > 82      6grp_total > 58      4grp_total > 47      6grp_highest_sub > Cu      6grp_high1_sub > Cu      6grp_total_sub > Cup      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 277
1 2 3 4 range
A 493.2
(3)
P 		266.1
(-3)
P 		279.9
(-2.6)
P 		267
(-3)
P 		227
B 484.5
(3)
P 		288.4
(-1.4)
P 		216.3
(-3)
P 		249
(-2.3)
P 		268
C 447
(3)
P 		234.9
(-3)
P 		246.2
(-2.7)
P 		257.5
(-2.4)
P 		212
avr 474.9
(3) 		263.1
(-2.6) 		247.5
(-3) 		257.8
(-2.7) 		227

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 211
1 2 3 4 5 6 range
A 359.1
(0.4)
P 		410
(2)
P 		248.7
(-3)
P 		351.9
(0.2)
P 		332.1
(-0.4)
P 		443
(3)
P 		194
B 318.3
(0.1)
P 		336.2
(0.8)
P 		232
(-3)
P 		346
(1.2)
P 		307.3
(-0.3)
P 		396.5
(3)
P 		165
C 375.6
(1)
P 		367.2
(0.4)
P 		319.4
(-3)
P 		319.2
(-3)
P 		390.5
(2.1)
P 		403.9
(3)
P 		85
avr 351
(0.4) 		371.1
(1.2) 		266.7
(-3) 		339
(-0.1) 		343.3
(0.1) 		414.5
(3) 		148
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 141
1 2 3 4 range
A 179.6
(3)
P 		57.8
(-2.2)
P 		73.2
(-1.5)
P 		39.1
(-3)
P 		141
B 154.5
(3)
P 		71.2
(-1.8)
P 		50.1
(-3)
P 		53.1
(-2.8)
P 		104
C 148
(3)
P 		67.5
(-1.6)
P 		85.8
(-0.6)
P 		43.4
(-3)
P 		105
avr 160.7
(3) 		65.5
(-1.9) 		69.7
(-1.7) 		45.2
(-3) 		116

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 94
1 2 3 4 5 6 range
A 66.2
(-2.2)
P 		145.8
(3)
P 		54.2
(-3)
P 		89.3
(-0.7)
P 		100.2
(0)
P 		107.8
(0.5)
P 		92
B 110.8
(0.6)
P 		111.9
(0.6)
P 		56.3
(-3)
P 		91.6
(-0.7)
P 		124.9
(1.5)
P 		147.8
(3)
P 		92
C 139.2
(3)
P 		112
(0.8)
P 		81.3
(-1.6)
P 		64.2
(-3)
P 		126.4
(2)
P 		135.2
(2.7)
P 		75
avr 105.4
(0.8) 		123.2
(2.4) 		63.9
(-3) 		81.7
(-1.4) 		117.2
(1.8) 		130.3
(3) 		66
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 186766_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.4685
Sequence Type Exemplar sequence
Representative Public ID ZK1248.10 NCBI
Target Description ZK1248.10 /REP_DB=WormBase Gene ID /WP=CE02894 /TR=Q23419 /GB=AAC71091.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_062755(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_062755 NCBI Caenorhabditis elegans ZK1248.10 (ZK1248.10) mRNA, complete cds. 11/11 A 
SNAP00000041376 ENSEMBL cdna:SNAP chromosome:CEL140:II:5824051:5827391:-1 11/11 None
GENEFINDER00000041389 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:5824022:5827391:-1 11/11 None
ZK1248.10 ENSEMBL cdna:known chromosome:CEL140:II:5823388:5827408:-1 gene:ZK1248.10 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:5824047-5827388(-) 100.0 100.0
Public Domain and Genome References
Gene Title
Ensembl ZK1248.10
Entrez Gene 173986 Entrez gene
SwissProt Q23419 EMBL-EBI
WormBase CE29155 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.21845.1.S1_AT similar to ZK1248.10 cfa
CHICKEN:GGAAFFX.2074.1.S1_AT similar to mKIAA1055 protein gga
HG-U133_PLUS_2:215640_AT KIAA1055 protein hs
HG-U133A_2:215640_AT KIAA1055 protein hs
HG-U133A:215640_AT KIAA1055 protein hs
HU35KSUBD:RC_R26293_AT KIAA1055 protein hs
HU35KSUBD:RC_H28210_AT KIAA1055 protein hs
HU35KSUBD:RC_AA447707_S_AT KIAA1055 protein hs
U133_X3P:HS.306386.0.S1_3P_AT KIAA1055 protein hs
U133_X3P:HS.126084.0.A1_3P_A_AT KIAA1055 protein hs
HG-U133A_2:212796_S_AT KIAA1055 protein hs
HG-U133_PLUS_2:212796_S_AT KIAA1055 protein hs
HG-U133A:212796_S_AT KIAA1055 protein hs
HG-U95AV2:39400_AT KIAA1055 protein hs
HG-U95E:68481_AT KIAA1055 protein hs
HG-U133_PLUS_2:215951_AT KIAA1055 protein hs
HG-U133A_2:215951_AT KIAA1055 protein hs
HG-U133A:215951_AT KIAA1055 protein hs
HG-U133_PLUS_2:230377_S_AT KIAA1055 protein hs
HG-U133B:230377_S_AT KIAA1055 protein hs
HG-U95D:91796_AT KIAA1055 protein hs
U133_X3P:HS.126084.1.A1_3P_AT KIAA1055 protein hs
MG-U74BV2:113749_AT RIKEN cDNA 1810061M12 gene mm
MG-U74BV2:107521_AT RIKEN cDNA 1810061M12 gene mm
MG-U74CV2:167050_R_AT RIKEN cDNA 1810061M12 gene mm
MG-U74CV2:167019_I_AT RIKEN cDNA 1810061M12 gene mm
MOE430B:1428508_AT RIKEN cDNA 1810061M12 gene mm
MOUSE430_2:1428508_AT RIKEN cDNA 1810061M12 gene mm
MU19KSUBB:TC31995_AT RIKEN cDNA 1810061M12 gene mm
MOUSE430_2:1444493_AT RIKEN cDNA 1810061M12 gene, mRNA (cDNA clone IMAGE:4039019) mm
MOE430B:1444493_AT RIKEN cDNA 1810061M12 gene, mRNA (cDNA clone IMAGE:4039019) mm
MU19KSUBA:TC19188_AT RIKEN cDNA 1810061M12 gene, mRNA (cDNA clone IMAGE:4039019) mm
MU19KSUBB:TC30945_AT RIKEN cDNA 1810061M12 gene, mRNA (cDNA clone IMAGE:4039019) mm
RAE230A:1372748_AT similar to KIAA1055 protein (predicted) rn
RAT230_2:1372748_AT similar to KIAA1055 protein (predicted) rn
RG-U34A:RC_AA799507_AT similar to KIAA1055 protein (predicted) rn
RG-U34B:RC_AI059020_AT Similar to KIAA1055 protein (predicted) rn
RG-U34C:RC_AI228491_AT Similar to KIAA1055 protein (predicted) rn
Protein Similarities
Method ID Description E-Value
blast AAC71091 Hypothetical protein ZK1248.10 [Caenorhabditis elegans] ref|NP_495156.1| ZK1248.10 [Caenorhabditis elegans] 0.0
blast CAE59197 Hypothetical protein CBG02508 [Caenorhabditis briggsae] 0.0
blast XP_693084 PREDICTED: similar to mKIAA1055 protein [Danio rerio] 1.0E-76
Protein Domains
Database ID Description E-Value
Pfam IPR000195 EMBL-EBI RabGAP/TBC domain 1.3E-47
Pfam IPR001849 EMBL-EBI Pleckstrin-like 1.1E-21
Sequence
Target Sequence 
>C. ELEGANS:186766_AT
aaacagattgatcttgacctcgctcgaactctgcccacgaataaacttttcgacgagcca
gattctgctaacatagaaaaactacgaaacgtactctacgccttccgataccataactct
cacgtcggctactgccaaggactcaatcgtcttgctgcaattgctctgttaaacctggat
gagcaggattcgttctggttccttgtagcatgtgtggaacatctccaacctgaaggatat
tacactagctcactgatcggagcggttgccgatcagaaagttctccgcgatcttgtagca
gaaaagcttccaaaattggctgcacatttgagagctcttgaagttgatctttcacttttc
gcgc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAACAGATTGATCTTGACCTCGCTC 448 129 2053 Antisense
CGAACTCTGCCCACGAATAAACTTT 329 251 2077 Antisense
AACTTTTCGACGAGCCAGATTCTGC 554 137 2096 Antisense
TTCCGATACCATAACTCTCACGTCG 99 697 2155 Antisense
TCACGTCGGCTACTGCCAAGGACTC 485 625 2172 Antisense
AAGGACTCAATCGTCTTGCTGCAAT 179 161 2189 Antisense
GCTGCAATTGCTCTGTTAAACCTGG 41 297 2206 Antisense
ATTCGTTCTGGTTCCTTGTAGCATG 535 9 2240 Antisense
ATATTACACTAGCTCACTGATCGGA 479 19 2289 Antisense
AGTTCTCCGCGATCTTGTAGCAGAA 8 65 2331 Antisense
GAAGTTGATCTTTCACTTTTCGCGC 453 337 2392 Antisense
Sequence Source Affymetrix Proprietary Database