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[186742_at] 7TM chemoreceptor, sre family

Description C50E10.10 /REP_DB=WormBase Gene ID /WP=CE19764 /TR=Q9TZJ3 /GB=AAC67440.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation
Cluster 6grp_total > 30      4grp_total > 02      6grp_cgc > 73      6grp_cgc_sub > 02_03      6grp_total_sub > Hat      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 98
1 2 3 4 range
A 25.6
(-1.4)
A 		26.6
(-1.3)
A 		6.6
(-3)
A 		78.5
(3)
M 		72
B 30.1
(-3)
A 		42.5
(-1.6)
A 		56.5
(0)
A 		82.1
(3)
M 		52
C 24.9
(-1.9)
A 		6.1
(-3)
A 		6.5
(-3)
A 		104.4
(3)
M 		98
avr 26.9
(-2.7) 		25.1
(-2.8) 		23.2
(-3) 		88.3
(3) 		65

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 51
1 2 3 4 5 6 range
A 10.9
(-3)
A 		27.1
(2.2)
A 		29.5
(3)
A 		26.4
(2)
A 		19.3
(-0.3)
A 		21.8
(0.5)
A 		19
B 31.8
(0)
A 		56.8
(3)
A 		48.8
(2)
A 		38.8
(0.8)
A 		20.9
(-1.3)
A 		6.6
(-3)
A 		50
C 6.2
(-3)
A 		26.9
(-0)
A 		21.9
(-0.8)
A 		42
(2.1)
A 		10.8
(-2.3)
A 		48.2
(3)
A 		42
avr 16.3
(-3) 		36.9
(3) 		33.4
(2) 		35.7
(2.7) 		17
(-2.8) 		25.5
(-0.3) 		21
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 16
1 2 3 4 range
A 9.3
(1.7)
A 		5.8
(-0.5)
A 		1.7
(-3)
A 		11.5
(3)
M 		10
B 9.6
(-3)
A 		10.5
(-2.3)
A 		13.1
(-0.3)
A 		17.5
(3)
M 		8
C 8.2
(-0.6)
A 		1.8
(-3)
A 		2.3
(-2.8)
A 		17.6
(3)
M 		16
avr 9
(-1) 		6
(-2.8) 		5.7
(-3) 		15.5
(3) 		10

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 17
1 2 3 4 5 6 range
A 2
(-3)
A 		9.6
(3)
A 		6.4
(0.5)
A 		6.7
(0.7)
A 		5.8
(0)
A 		5.3
(-0.4)
A 		8
B 11.1
(0.1)
A 		18.9
(3)
A 		11.9
(0.4)
A 		10.3
(-0.1)
A 		8.5
(-0.8)
A 		2.5
(-3)
A 		16
C 2.3
(-3)
A 		8.2
(-0.4)
A 		5.6
(-1.6)
A 		8.5
(-0.3)
A 		3.5
(-2.5)
A 		16.1
(3)
A 		14
avr 5.1
(-3) 		12.2
(3) 		8
(-0.5) 		8.5
(-0.1) 		5.9
(-2.3) 		8
(-0.5) 		7
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 186742_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3793
Sequence Type Exemplar sequence
Representative Public ID C50E10.10 NCBI
Target Description C50E10.10 /REP_DB=WormBase Gene ID /WP=CE19764 /TR=Q9TZJ3 /GB=AAC67440.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064213(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_064213 NCBI Caenorhabditis elegans Serpentine Receptor, class E (epsilon) family member (sre-51) (sre-51) mRNA, complete cds. 11/11 None
GENEFINDER00000034847 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:12311763:12320973:1 10/11 None
C50E10.10 ENSEMBL cdna:known chromosome:CEL140:II:12311775:12313563:1 gene:C50E10.10 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:12311771-12313972(+) 87.7 100.0
Public Domain and Genome References
Gene Title 7TM chemoreceptor, sre family
Gene Symbol sre-51
Ensembl C50E10.10
Entrez Gene 183671 Entrez gene
SwissProt Q965I0 EMBL-EBI
WormBase CE38164 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast NP_496614 Serpentine Receptor, class E (epsilon) family member (sre-51) [Caenorhabditis elegans] gb|AAK73859.5| Serpentine receptor, class e (epsilon) protein 51 [Caenorhabditis elegans] 0.0
blast T33505 hypothetical protein C50E10.10 - Caenorhabditis elegans 0.0
blast CAE73490 Hypothetical protein CBG20945 [Caenorhabditis briggsae] 1.0E-138
blast CAE73490 Hypothetical protein CBG20945 [Caenorhabditis briggsae] 1.0E-132
Protein Domains
Database ID Description E-Value
Pfam IPR004151 EMBL-EBI C. elegans Sre G protein-coupled chemoreceptor 1.1E-83
Pfam IPR004151 EMBL-EBI C. elegans Sre G protein-coupled chemoreceptor 3.6E-78
Pfam IPR004151 EMBL-EBI C. elegans Sre G protein-coupled chemoreceptor 7.7E-29
Pfam IPR004151 EMBL-EBI C. elegans Sre G protein-coupled chemoreceptor 1.7E-79
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_496614.3 6 27-46,58-77,122-144,165-187,192-214,251-273
C50E10.10 6 20-42,54-73,118-140,161-183,188-210,247-269
GENEFINDER00000034847 13 27-46,58-77,122-144,165-187,192-214,252-274,289-308,380-402,417-435,493-515,520-542,580-602,612-634
Sequence
Target Sequence 
>C. ELEGANS:186742_AT
gagctgtttgtgttgtctacctaattttatggctggtcaacgagcgacatcgcaaaaatc
tcacagctcgcggagcatatcatttggctcagcaatttcaagtcaaggagaatattcgac
atataatgctggctcgaaatataataagttgtgccacgttctttgtagcagtcacatgtg
ggttattaatgacaatagtacttgatttaataccaatttggctcaaaaatccaatggctc
agtgtattgagaattgcatatttttgaatccgctccttatctgctccgtgacattattca
gtgtgcctgcgtggaagaacgagttttgtcagagcattcctatttttcgaaaatttcgga
acgaatcaataaccgttcgaaaatcattgggccctgatagtgatacgaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAGCTGTTTGTGTTGTCTACCTAAT 496 387 611 Antisense
ATGGCTGGTCAACGAGCGACATCGC 591 53 639 Antisense
GCAAAAATCTCACAGCTCGCGGAGC 588 317 662 Antisense
AGCTCGCGGAGCATATCATTTGGCT 166 81 675 Antisense
GTGCCACGTTCTTTGTAGCAGTCAC 144 479 761 Antisense
TTGCATATTTTTGAATCCGCTCCTT 376 703 864 Antisense
CTTATCTGCTCCGTGACATTATTCA 211 223 886 Antisense
GACATTATTCAGTGTGCCTGCGTGG 313 369 900 Antisense
TTGTCAGAGCATTCCTATTTTTCGA 548 707 936 Antisense
ACCGTTCGAAAATCATTGGGCCCTG 29 81 982 Antisense
CATTGGGCCCTGATAGTGATACGAA 613 217 995 Antisense
Sequence Source Affymetrix Proprietary Database