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[186594_at]

Description F45C12.16 /REP_DB=WormBase Gene ID /WP=CE10466 /TR=O16750 /GB=AAB66213.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation
Cluster 4grp_high_8_8 > 13      6grp_total > 03      4grp_total > 02      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 80
1 2 3 4 range
A 56.1
(-1.1)
P 		31.5
(-3)
A 		47.5
(-1.8)
P 		111
(3)
P 		80
B 61.8
(-1.8)
P 		59.4
(-2.3)
A 		56
(-3)
A 		85.1
(3)
P 		29
C 48.7
(-3)
P 		54.8
(-2.3)
P 		56.2
(-2.2)
P 		102.5
(3)
P 		54
avr 55.5
(-2.2) 		48.6
(-3) 		53.2
(-2.5) 		99.5
(3) 		51

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 54
1 2 3 4 5 6 range
A 43.9
(1.1)
A 		44.2
(1.1)
P 		39.9
(0.4)
P 		55.3
(3)
P 		37.3
(-0)
P 		19.6
(-3)
A 		36
B 73.1
(3)
P 		60
(1.4)
P 		40.6
(-1.1)
P 		43.9
(-0.7)
A 		50.1
(0.1)
P 		25.1
(-3)
A 		48
C 43
(-0.1)
P 		55.8
(3)
P 		46.6
(0.8)
P 		45.5
(0.5)
P 		53
(2.3)
A 		31.1
(-3)
M 		25
avr 53.3
(3) 		53.3
(3) 		42.4
(0.7) 		48.2
(1.9) 		46.8
(1.6) 		25.3
(-3) 		28
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 14
1 2 3 4 range
A 20.4
(3)
P 		6.8
(-3)
A 		12.4
(-0.5)
P 		16.2
(1.1)
P 		14
B 19.7
(3)
P 		14.7
(-1.5)
A 		13
(-3)
A 		18.1
(1.6)
P 		7
C 16.1
(-2.5)
P 		15.8
(-3)
P 		19.6
(3)
P 		17.3
(-0.6)
P 		4
avr 18.7
(3) 		12.4
(-3) 		15
(-0.5) 		17.2
(1.6) 		6

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 21
1 2 3 4 5 6 range
A 8.1
(-1.2)
A 		15.7
(3)
P 		8.7
(-0.9)
P 		14
(2.1)
P 		11.3
(0.6)
P 		4.8
(-3)
A 		11
B 25.4
(3)
P 		20
(1)
P 		9.9
(-2.8)
P 		11.6
(-2.2)
A 		20.3
(1.1)
P 		9.4
(-3)
A 		16
C 15.9
(2)
P 		17
(2.9)
P 		11.9
(-1)
P 		9.2
(-3)
P 		17.2
(3)
A 		10.4
(-2.1)
M 		8
avr 16.5
(2.3) 		17.6
(3) 		10.2
(-1.7) 		11.6
(-0.8) 		16.3
(2.2) 		8.2
(-3) 		9
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 186594_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.4356
Sequence Type Exemplar sequence
Representative Public ID F45C12.16 NCBI
Target Description F45C12.16 /REP_DB=WormBase Gene ID /WP=CE10466 /TR=O16750 /GB=AAB66213.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_061662(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_061662 NCBI Caenorhabditis elegans F45C12.16 (F45C12.16) mRNA, complete cds. 11/11 None
SNAP00000033198 ENSEMBL cdna:SNAP chromosome:CEL140:II:1736869:1738826:-1 11/11 None
GENEFINDER00000033201 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:1736962:1738947:-1 10/11 None
F45C12.16 ENSEMBL cdna:known chromosome:CEL140:II:1736869:1738947:-1 gene:F45C12.16 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:1736867-1738946(-) 100.0 100.0
Public Domain and Genome References
Gene Title
Ensembl F45C12.16
Entrez Gene 185777 Entrez gene
SwissProt O16750 EMBL-EBI
WormBase CE10466 Wormbase
Functional Annotations
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4714 transmembrane receptor protein tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5006 epidermal growth factor receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB66213 Hypothetical protein F45C12.16 [Caenorhabditis elegans] ref|NP_494063.1| F45C12.16 [Caenorhabditis elegans] 0.0
blast AAC67482 Hypothetical protein F58E1.4 [Caenorhabditis elegans] ref|NP_494038.1| F58E1.4 [Caenorhabditis elegans] 1.0E-158
blast AAC67482 Hypothetical protein F58E1.4 [Caenorhabditis elegans] ref|NP_494038.1| F58E1.4 [Caenorhabditis elegans] 1.0E-157
blast AAC67482 Hypothetical protein F58E1.4 [Caenorhabditis elegans] ref|NP_494038.1| F58E1.4 [Caenorhabditis elegans] 1.0E-144
blast AAF40000 Hypothetical protein ZK355.6 [Caenorhabditis elegans] ref|NP_494405.1| ZK355.6 [Caenorhabditis elegans] 4.0E-98
blast AAF39998 Hypothetical protein ZK355.1 [Caenorhabditis elegans] ref|NP_494403.1| ZK355.1 [Caenorhabditis elegans] 1.0E-97
Protein Domains
Database ID Description E-Value
Pfam IPR000494 EMBL-EBI Epidermal growth-factor receptor (EGFR), L domain 8.2E-13
Pfam IPR000494 EMBL-EBI Epidermal growth-factor receptor (EGFR), L domain 9.8E-32
Pfam IPR000494 EMBL-EBI Epidermal growth-factor receptor (EGFR), L domain 8.2E-13
Pfam IPR000494 EMBL-EBI Epidermal growth-factor receptor (EGFR), L domain 9.8E-32
Sequence
Target Sequence 
>C. ELEGANS:186594_AT
gagaacttgcactctaacttctgtgtaacctaccaggaaatgttcatttttatgacccaa
gatgtttactttaaaaacttgcatgcgaactattgcgagggcaaagaacaatacgttaaa
caggcactggatatgtatgaaatttgttggctcaccactctgagagcattaaaaccaaat
tgcaaaattatcggcggtgatttgaagattcagagtggagatgaagcgtatgtattcaaa
ttggaaaatgtgcagtatttattcgggtcggtttcgattcacaacactaatttgaagaat
attgattttttggccaatttacggagcatggcagttttgaatgatgaacctgctataaag
attgtgtctaatcaaaaccttaagtatgcctatttgcccgtactttcgactataatcaca
aagcaccagcggacagttgtagttcacaataaccctctattgcccagtgattcatttttc
ctatacccaatgcgttattcaacgaatgcaaagtttgttggtgatcaatttgaaaatgga
acgccatcaggaatactaagctt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAGAACTTGCACTCTAACTTCTGTG 623 391 925 Antisense
CTAACTTCTGTGTAACCTACCAGGA 250 225 938 Antisense
GTTGGCTCACCACTCTGAGAGCATT 480 435 1070 Antisense
GTGCAGTATTTATTCGGGTCGGTTT 278 455 1174 Antisense
GGTCGGTTTCGATTCACAACACTAA 161 501 1190 Antisense
TAAGTATGCCTATTTGCCCGTACTT 385 637 1305 Antisense
TTGCCCGTACTTTCGACTATAATCA 333 699 1318 Antisense
TCACAATAACCCTCTATTGCCCAGT 7 629 1368 Antisense
ATTGCCCAGTGATTCATTTTTCCTA 495 7 1383 Antisense
ATTTTTCCTATACCCAATGCGTTAT 138 15 1398 Antisense
GAACGCCATCAGGAATACTAAGCTT 300 347 1463 Antisense
Sequence Source Affymetrix Proprietary Database