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[186473_at]

Description C01B12.3 /REP_DB=WormBase Gene ID /WP=CE07791 /TR=O17206 /GB=AAB70976.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 37      6grp_high1_10_10 > 72      4grp_highest_8_8 > 46      4grp_high_8_8 > 02      6grp_highest_nonorm > 72      6grp_total > 70      4grp_total > 14      6grp_highest_sub > 03_04      6grp_high1_sub > 04      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 421
1 2 3 4 range
A 410.6
(1.5)
P 		149.3
(-3)
P 		201.2
(-2.1)
P 		499.3
(3)
P 		350
B 351.8
(-0.2)
P 		204.6
(-2.3)
P 		157.7
(-3)
P 		570.2
(3)
P 		413
C 403.7
(2.3)
P 		187.5
(-3)
P 		207.7
(-2.5)
P 		432.9
(3)
P 		245
avr 388.7
(0.9) 		180.5
(-3) 		188.9
(-2.8) 		500.8
(3) 		320

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 398
1 2 3 4 5 6 range
A 494.8
(1.7)
P 		348
(-2.8)
P 		536.8
(3)
P 		499
(1.8)
P 		342.4
(-3)
P 		407.9
(-1)
P 		194
B 351.7
(-3)
P 		412.8
(-0.8)
P 		491.3
(2.1)
P 		517.1
(3)
P 		470.6
(1.3)
P 		396
(-1.4)
P 		165
C 283.8
(-3)
P 		499.6
(0.3)
P 		407.8
(-1.1)
P 		681.6
(3)
P 		294.2
(-2.8)
P 		442.6
(-0.6)
P 		398
avr 376.8
(-2.8) 		420.1
(-1.4) 		478.6
(0.3) 		565.9
(3) 		369.1
(-3) 		415.5
(-1.6) 		197
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 117
1 2 3 4 range
A 149.5
(3)
P 		32.4
(-3)
P 		52.6
(-2)
P 		73.1
(-0.9)
P 		117
B 112.2
(2.3)
P 		50.5
(-2)
P 		36.5
(-3)
P 		121.5
(3)
P 		85
C 133.6
(3)
P 		53.9
(-3)
P 		72.4
(-1.6)
P 		73
(-1.6)
P 		80
avr 131.8
(3) 		45.6
(-3) 		53.8
(-2.4) 		89.2
(0) 		86

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 100
1 2 3 4 5 6 range
A 91.2
(-3)
P 		123.8
(2.5)
P 		116.9
(1.4)
P 		126.6
(3)
P 		103.3
(-0.9)
P 		99.3
(-1.6)
P 		35
B 122.4
(-2.7)
P 		137.4
(-1.5)
P 		119.3
(-3)
P 		136.9
(-1.5)
P 		191.2
(3)
P 		147.7
(-0.6)
P 		72
C 105.2
(-2)
P 		152.4
(3)
P 		103.8
(-2.1)
P 		137.1
(1.4)
P 		95.2
(-3)
P 		148.2
(2.6)
P 		57
avr 106.3
(-3) 		137.9
(3) 		113.3
(-1.7) 		133.5
(2.2) 		129.9
(1.5) 		131.7
(1.8) 		32
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 186473_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.4186
Sequence Type Exemplar sequence
Representative Public ID C01B12.3 NCBI
Target Description C01B12.3 /REP_DB=WormBase Gene ID /WP=CE07791 /TR=O17206 /GB=AAB70976.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_061231(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_061231 NCBI Caenorhabditis elegans C01B12.3 (C01B12.3) mRNA, complete cds. 11/11 None
SNAP00000043175 ENSEMBL cdna:SNAP chromosome:CEL140:II:12986:15858:1 11/11 None
GENEFINDER00000043182 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:12986:15858:1 11/11 None
C01B12.3 ENSEMBL cdna:known chromosome:CEL140:II:12985:15998:1 gene:C01B12.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:12985-15858(+) 100.0 100.0
Public Domain and Genome References
Gene Title
Ensembl C01B12.3
Entrez Gene 173379 Entrez gene
SwissProt O17206 EMBL-EBI
WormBase CE07791 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.24387.1.S1_AT similar to bestrophin cfa
CHICKEN:GGAAFFX.4522.1.S1_AT similar to bestrophin gga
CHICKEN:GGAAFFX.4522.2.S1_AT similar to bestrophin gga
HG-U133_PLUS_2:207671_S_AT vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
HG-U133A:207671_S_AT vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
HG-FOCUS:207671_S_AT vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
HG-U133A_2:207671_S_AT vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
HU35KSUBA:HUM_ALU_AT vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
HU35KSUBB:HUM_ALU_AT vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
HU35KSUBC:HUM_ALU_AT vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
HU35KSUBD:HUM_ALU_AT vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
HUGENEFL:HUM_ALU_AT vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
HC-G110:HUM_ALU_AT vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
U133_X3P:G4759309_3P_A_AT vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
U133_X3P:HS2.182771.3.S1_3P_S_AT vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
U133_X3P:HS2.182771.3.S1_3P_AT vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
U133_X3P:1554442_3P_AT vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
HG-U133_PLUS_2:1554442_AT vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
HG-U133_PLUS_2:1554443_S_AT vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
HG-U95AV2:38601_AT vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
HG-U133_PLUS_2:215488_AT Vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
HG-U133A_2:215488_AT Vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
HG-U133A:215488_AT Vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
U133_X3P:HS.181686.0.A1_3P_AT Vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
U133_X3P:HS.167344.0.S1_3P_X_AT Vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
U133_X3P:HS.167344.0.S1_3P_AT Vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
U133_X3P:215488_3P_AT Vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
HG-U133_PLUS_2:243702_AT Vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
HG-U133B:243702_AT Vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
HG-U95AV2:36428_AT Vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
HG-U95E:67160_AT Vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
HG-U133_PLUS_2:237293_AT Vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
HG-U133B:237293_AT Vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
HG-U95E:74755_AT Vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
U133_X3P:HS.132319.0.A1_3P_AT Vitelliform macular dystrophy 2 (Best disease, bestrophin) hs
MG-U74CV2:165647_F_AT vitelliform macular dystrophy 2 homolog (human) mm
MOE430B:1428841_AT vitelliform macular dystrophy 2 homolog (human) mm
MOUSE430_2:1428841_AT vitelliform macular dystrophy 2 homolog (human) mm
Protein Similarities
Method ID Description E-Value
blast AAB70976 Hypothetical protein C01B12.3 [Caenorhabditis elegans] ref|NP_493632.1| C01B12.3 [Caenorhabditis elegans] 0.0
blast CAE62861 Hypothetical protein CBG07044 [Caenorhabditis briggsae] 0.0
blast CAE62860 Hypothetical protein CBG07043 [Caenorhabditis briggsae] 1.0E-139
Protein Domains
Database ID Description E-Value
Pfam IPR000615 EMBL-EBI Bestrophin 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_493632.1 4 32-54,74-96,232-254,274-291
C01B12.3 4 32-54,74-96,232-254,274-291
SNAP00000043175 4 32-54,74-96,232-254,274-291
GENEFINDER00000043182 4 32-54,74-96,232-254,274-291
Sequence
Target Sequence 
>C. ELEGANS:186473_AT
gtgggtctgaaacacacgcgtgataatagtaattatgcttctggcgaatctctagcattt
tcgaatagctttgccaatggtggtaggaaactgagtgagatgtttcgaagaatgagagct
gggagcagaattggtgataggtataggaaacgcaactcgtcagcacaagactttgaaaat
ggaatggcaaaaaaaaacagtattgatgaaaatgcagatattcacagtaataggctcgat
caagcatccggtacaccaaaatcaggaaggctttggagttcgatgcctcaaacacaattg
gaagaaatgcttaagaataaaaactttaactctcctgtcaaatacaacactgatgggatg
aaagaccgagagcttcaaaatccaacaccaatcactgatcacattgatttgcctttgcat
gtggcgagtagtcaatcatggtttaacgaaagtttaccagtaatcaaagaggaggaagaa
gctaaaagaaaatccaacacggatacagagtctccaaagtctagtaagcatt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTGGGTCTGAAACACACGCGTGATA 568 487 1222 Antisense
GCTTCTGGCGAATCTCTAGCATTTT 145 307 1258 Antisense
AGCATTTTCGAATAGCTTTGCCAAT 329 77 1275 Antisense
GAAACGCAACTCGTCAGCACAAGAC 532 357 1368 Antisense
TAGGCTCGATCAAGCATCCGGTACA 619 163 1452 Antisense
GGCTTTGGAGTTCGATGCCTCAAAC 485 537 1490 Antisense
AACTTTAACTCTCCTGTCAAATACA 684 137 1543 Antisense
AATCCAACACCAATCACTGATCACA 444 167 1600 Antisense
GATCACATTGATTTGCCTTTGCATG 415 421 1618 Antisense
GCCTTTGCATGTGGCGAGTAGTCAA 647 281 1632 Antisense
GAGTCTCCAAAGTCTAGTAAGCATT 8 401 1729 Antisense
Sequence Source Affymetrix Proprietary Database